Page last updated: 2024-10-27

gabapentin and Acute Pain

gabapentin has been researched along with Acute Pain in 22 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.

Research Excerpts

ExcerptRelevanceReference
" Gabapentin was used as an adjunct for the management of acute pain in approximately half of enhanced recovery programs."8.95Gabapentin can decrease acute pain and morphine consumption in spinal surgery patients: A meta-analysis of randomized controlled trials. ( Li, C; Peng, C; Qu, J; Wu, D, 2017)
" Further studies should determine the optimal dose and whether pregabalin is superior to gabapentin in controlling acute pain after spine surgery."8.95A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery. ( Liu, B; Liu, R; Wang, L, 2017)
"Widely used for acute pain management, the clinical benefit from perioperative use of gabapentinoids is uncertain."7.96Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis. ( Cossi, MJ; Lauzier, F; Leblanc, G; Neveu, X; Perron, C; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2020)
"Our study will provide the best level of evidence to inform the effect of gabapentinoids in the management of postoperative acute pain."7.91Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis. ( Cossi, MJ; Lauzier, F; Leblanc, G; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2019)
"The aim of the present study was to investigate the possible antinociceptive effects of systemic administration of tramadol and gabapentin either alone or in combination on acute pain models in mice."7.78The antinociceptive effects of systemic administration of tramadol, gabapentin and their combination on mice model of acute pain. ( Alaçam, B; Aydin, ON; Ek, RO; Şen, S; Temoçin, S; Uğur, B, 2012)
"Gabapentinoid use has increased substantially in the past several years after initial promising data with regard to acute perioperative pain control."6.61The role of gabapentinoids in acute and chronic pain after surgery. ( Habib, AS; Kumar, AH, 2019)
"It is a novel drug used for the treatment of postoperative pain with antihyperalgesic properties and a unique mechanism of action."6.50Gabapentin in acute postoperative pain management. ( Challa, CK; Chang, CY; Eloy, JD; Shah, J, 2014)
"Paclitaxel can cause an acute pain syndrome (P-APS), considered to be an acute form of neuropathy and chronic chemotherapy-induced peripheral neuropathy (CIPN)."5.22Can pregabalin prevent paclitaxel-associated neuropathy?--An ACCRU pilot trial. ( Atherton, PJ; Lafky, J; Loprinzi, CL; Pachman, DR; Ruddy, KJ; Seisler, D; Shinde, SS; Soori, G, 2016)
" Gabapentin was used as an adjunct for the management of acute pain in approximately half of enhanced recovery programs."4.95Gabapentin can decrease acute pain and morphine consumption in spinal surgery patients: A meta-analysis of randomized controlled trials. ( Li, C; Peng, C; Qu, J; Wu, D, 2017)
" Further studies should determine the optimal dose and whether pregabalin is superior to gabapentin in controlling acute pain after spine surgery."4.95A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery. ( Liu, B; Liu, R; Wang, L, 2017)
"Widely used for acute pain management, the clinical benefit from perioperative use of gabapentinoids is uncertain."3.96Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis. ( Cossi, MJ; Lauzier, F; Leblanc, G; Neveu, X; Perron, C; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2020)
"Our study will provide the best level of evidence to inform the effect of gabapentinoids in the management of postoperative acute pain."3.91Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis. ( Cossi, MJ; Lauzier, F; Leblanc, G; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2019)
"The aim of the present study was to investigate the possible antinociceptive effects of systemic administration of tramadol and gabapentin either alone or in combination on acute pain models in mice."3.78The antinociceptive effects of systemic administration of tramadol, gabapentin and their combination on mice model of acute pain. ( Alaçam, B; Aydin, ON; Ek, RO; Şen, S; Temoçin, S; Uğur, B, 2012)
"Acute postoperative pain is associated with the development of persistent postsurgical pain, but it is unclear which aspect is most estimable."2.90Factors Associated With Acute Pain Estimation, Postoperative Pain Resolution, Opioid Cessation, and Recovery: Secondary Analysis of a Randomized Clinical Trial. ( Carroll, I; Clay, D; Costouros, JG; Cramer, E; Curtin, C; Dirbas, FM; Goodman, S; Hah, JM; Hilmoe, H; Huddleston, J; Mackey, SC; Maloney, WJ; McCue, R; Ruchelli, G; Schmidt, P; Sharifzadeh, Y; Shrager, J; Trafton, J, 2019)
"Trials of acute pain are complicated by the need to obtain consent, to randomize participants expeditiously while optimally treating pain."2.82Addressing challenges of clinical trials in acute pain: The Pain Management of Vaso-occlusive Crisis in Children and Young Adults with Sickle Cell Disease Study. ( Anghelescu, DL; Cancio, MI; Christensen, R; Faughnan, LG; Hankins, JS; James, DM; Kang, G; Nottage, KA; Richardson, J; Smeltzer, M; Wang, WC, 2016)
"Gabapentinoid use has increased substantially in the past several years after initial promising data with regard to acute perioperative pain control."2.61The role of gabapentinoids in acute and chronic pain after surgery. ( Habib, AS; Kumar, AH, 2019)
"It is a novel drug used for the treatment of postoperative pain with antihyperalgesic properties and a unique mechanism of action."2.50Gabapentin in acute postoperative pain management. ( Challa, CK; Chang, CY; Eloy, JD; Shah, J, 2014)
"Recent awareness that chronic pain may occur after childbirth has prompted clinicians and researchers to investigate this topic."2.49Chronic pain after childbirth. ( Bollag, L; Landau, R; Ortner, C, 2013)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's15 (68.18)24.3611
2020's7 (31.82)2.80

Authors

AuthorsStudies
Zhang, J1
Chen, SR1
Zhou, MH1
Jin, D1
Chen, H1
Wang, L2
DePinho, RA1
Pan, HL1
Fowler, C1
Chu, AW1
Guo, N1
Ansari, JR1
Shafer, SL1
Flood, PD1
Iturri, F1
Valencia, L1
Honorato, C1
Martínez, A1
Valero, R1
Fàbregas, N1
Verret, M3
Lauzier, F3
Zarychanski, R3
Perron, C1
Savard, X2
Pinard, AM2
Leblanc, G2
Cossi, MJ2
Neveu, X1
Turgeon, AF3
Araujo, BLC1
Su, PP1
Guan, Z1
Peng, C1
Li, C1
Qu, J1
Wu, D1
Liu, B1
Liu, R1
Kendall, MC1
Castro-Alves, LJ1
Sanders, J1
Cameron, C1
Dawes, P1
Hah, JM1
Cramer, E1
Hilmoe, H1
Schmidt, P1
McCue, R1
Trafton, J1
Clay, D1
Sharifzadeh, Y1
Ruchelli, G1
Goodman, S1
Huddleston, J1
Maloney, WJ1
Dirbas, FM1
Shrager, J1
Costouros, JG1
Curtin, C1
Mackey, SC1
Carroll, I1
Davison, SN1
Kumar, AH1
Habib, AS1
Landau, R1
Bollag, L1
Ortner, C1
Chang, CY1
Challa, CK1
Shah, J1
Eloy, JD1
Shinde, SS1
Seisler, D1
Soori, G1
Atherton, PJ1
Pachman, DR1
Lafky, J1
Ruddy, KJ1
Loprinzi, CL1
Nottage, KA1
Hankins, JS1
Faughnan, LG1
James, DM1
Richardson, J1
Christensen, R1
Kang, G1
Smeltzer, M1
Cancio, MI1
Wang, WC1
Anghelescu, DL1
Badiola, IJ1
Zhu, CZ1
Mills, CD1
Hsieh, GC1
Zhong, C1
Mikusa, J1
Lewis, LG1
Gauvin, D1
Lee, CH1
Decker, MW1
Bannon, AW1
Rueter, LE1
Joshi, SK1
Aydin, ON1
Ek, RO1
Temoçin, S1
Uğur, B1
Alaçam, B1
Şen, S1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind Randomized Placebo-Controlled Clinical Trial of Preoperative Gabapentin Prior to Vaginal Apical Suspension Prolapse Procedures[NCT05658887]Phase 4110 participants (Anticipated)Interventional2023-01-01Enrolling by invitation
Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia With Isobaric Bupivacaine in Patients Undergoing Surgery to Treat Skin and Soft Tissue Tumors of the Lower Limbs[NCT04741880]Phase 2/Phase 366 participants (Anticipated)Interventional2021-06-17Recruiting
"Preoperative Gabapentin and Its Effects on Postoperative Analgesia in Patients Undergoing Cosmetic Breast Surgery"[NCT05997355]100 participants (Anticipated)Interventional2023-09-01Not yet recruiting
Use of Oral Pregabalin as Preemptive Analgesia in Abdominal Hysterectomy: Evaluation of Postoperative Pain and Opioid Consumption[NCT04495374]Phase 458 participants (Actual)Interventional2019-09-02Terminated (stopped due to Due to an atypical health scenario caused by the COVID-19 pandemic)
Stanford Accelerated Recovery Trial (START)[NCT01067144]Phase 3422 participants (Actual)Interventional2010-05-31Terminated (stopped due to Trial met futility stopping point)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Doses of Opioids Used as Analgesic Rescue in the Postoperative Period

Evaluation of the number of intravenous opioid doses used within 24 hours of postoperative abdominal hysterectomy surgery in patients who used pregabalin 300mg or not as preemptive analgesia (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)

Interventionnumber of doses (Median)
Group P(0) - Placebo4
Group P(1) - Pregabalin 300mg2

Number of Participants With Dizziness Between the Intervention and Control Groups

• Assess the presence of adverse effects such as nausea and vomiting, itching and dizziness, comparing the intervention group that used pregabalin with the placebo group (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery) and also immediately in the post-anesthetic recovery room

InterventionParticipants (Count of Participants)
Group P(0) - Placebo7
Group P(1) - Pregabalin 300mg16

Postoperative Pain Assessed 24 Hours After Abdominal Hysterectomy Surgery, Using the McGill Pain Questionnaire

Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single 300mg dose of pregabalin or placebo as preemptive analgesia, using the McGill pain questionnaire, which consists of 20 word groups , and each group can contain from 2 to 6 descriptive words, these descriptors are placed in an increasing order of magnitude in relation to the intensity. The left of each word has a numerical value in an attempt to represent the intensity of the descriptor. For the analysis of the answers, the total number of words chosen in each subgroup by the patient was used to qualify his pain, the minimum value being equal to 0 (zero), if the patient chose not to choose any descriptor, and the maximum value would be 20, as the patient can choose only one descriptor for each subgroup. The quantitative pain index was also evaluated, which represents the sum of the values of each descriptor chosen by the patient, with a minimum value of 0 and a maximum of 78. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)

Interventionscore on a scale (Median)
Group P(0) - Placebo28.5
Group P(1) - Pregabalin 300mg12

Postoperative Pain in Active Movement Assessed 24 Hours After Abdominal Hysterectomy Surgery Using the Visual Analog Scale (VAS)

Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single dose of pregabalin 300mg or placebo as preemptive analgesia, using the visual analog scale (VAS) consisting of a 10 cm (cm) line ) graduated in natural number intervals, starting at 0 (zero) until reaching 10 (ten), associated with the numbers, drawings related to the pain presented by the patient at the moment, in which the absence of pain (0 ) there is a happy face, and as the numerical value increases, the drawn face will represent the intensity of pain, up to the value of 10, where a face with crying characteristics is found, indicating greater pain. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)

Interventionscore on a scale (Mean)
Group P(0) - Placebo7
Group P(1) - Pregabalin 300mg4

Postoperative Pain in Rest Assessed 24 Hours After Abdominal Hysterectomy Surgery Using the Visual Analog Scale (VAS)

Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single dose of pregabalin 300mg or placebo as preemptive analgesia, using the visual analog scale (VAS) consisting of a 10 cm (cm) line ) graduated in natural number intervals, starting at 0 (zero) until reaching 10 (ten), associated with the numbers, drawings related to the pain presented by the patient at the moment, in which the absence of pain (0 ) there is a happy face, and as the numerical value increases, the drawn face will represent the intensity of pain, up to the value of 10, where a face with crying characteristics is found, indicating greater pain. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)

Interventionscore on a scale (Mean)
Group P(0) - Placebo5
Group P(1) - Pregabalin 300mg2

Time Required for the Use of the First Dose of Opioid as an Analgesic Rescue in the Postoperative Period

• Evaluation of the time between the end of abdominal hysterectomy surgery and the patient's request for the use of the first dose of intravenous opioid as an analgesic rescue, comparing between patients who used or not pregabalin 300mg as preemptive analgesia (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)

InterventionTime in minutes (Median)
Group P(0) - Placebo170
Group P(1) - Pregabalin 300mg106

Count of Participants With Continued Opioid Use at 1 Year

Continued opioid use was defined as any report of any continued opioid use at Year 1. (NCT01067144)
Timeframe: Year 1

InterventionParticipants (Count of Participants)
Control3
Gabapentin4

Count of Participants With Continued Opioid Use at 6 Months

Continued opioid use was defined as any report of any continued opioid use at Month 6. (NCT01067144)
Timeframe: Month 6

InterventionParticipants (Count of Participants)
Control4
Gabapentin5

Count of Participants With Continued Pain at 1 Year

"Continued pain was defined as a report of at least 1 average pain at the surgical site (as reported by the patient on a scale of 0-10, with lower scores corresponding to less pain (0 = no pain) and higher scores corresponding to more pain)." (NCT01067144)
Timeframe: Year 1

InterventionParticipants (Count of Participants)
Control18
Gabapentin21

Count of Participants With Continued Pain at 6 Months

"Continued pain was defined as a report of at least 1 average pain at the surgical site (as reported by the patient on a scale of 0-10, with lower scores corresponding to less pain (0 = no pain) and higher scores corresponding to more pain)." (NCT01067144)
Timeframe: Month 6

InterventionParticipants (Count of Participants)
Control37
Gabapentin42

Time to Opioid Cessation

Time to opioid cessation was defined as 5 consecutive reports of no opioid use. Planned call frequency was daily for 3 months, weekly thereafter up to 6 months, and monthly thereafter up to 2 years after surgery. (NCT01067144)
Timeframe: Up to 2 years

Interventiondays (Median)
Control32
Gabapentin25

Time to Pain Resolution

"Time to pain resolution was defined as 5 consecutive reports of 0 average pain at the surgical site (as reported by the patient on a scale of 0-10, with lower scores corresponding to less pain (0 = no pain) and higher scores corresponding to more pain). Planned call frequency was daily for 3 months, weekly thereafter up to 6 months, and monthly thereafter up to 2 years after surgery." (NCT01067144)
Timeframe: Up to 2 years

Interventiondays (Median)
Control73
Gabapentin84

Reviews

7 reviews available for gabapentin and Acute Pain

ArticleYear
Narrative review of acute post-craniotomy pain. Concept and strategies for prevention and treatment of pain.
    Revista espanola de anestesiologia y reanimacion, 2020, Volume: 67, Issue:2

    Topics: Acupuncture Analgesia; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory A

2020
Gabapentin can decrease acute pain and morphine consumption in spinal surgery patients: A meta-analysis of randomized controlled trials.
    Medicine, 2017, Volume: 96, Issue:15

    Topics: Acute Pain; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabap

2017
A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery.
    Medicine, 2017, Volume: 96, Issue:37

    Topics: Acute Pain; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hu

2017
The role of gabapentinoids in acute and chronic pain after surgery.
    Current opinion in anaesthesiology, 2019, Volume: 32, Issue:5

    Topics: Acute Pain; Analgesia; Analgesics; Chronic Pain; Enhanced Recovery After Surgery; Gabapentin; Humans

2019
Chronic pain after childbirth.
    International journal of obstetric anesthesia, 2013, Volume: 22, Issue:2

    Topics: Acute Pain; Adrenergic alpha-Agonists; Adult; Amines; Analgesics; Anesthetics, Dissociative; Cesarea

2013
Gabapentin in acute postoperative pain management.
    BioMed research international, 2014, Volume: 2014

    Topics: Acute Pain; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric

2014
Can Chronic Pain Be Prevented?
    Anesthesiology clinics, 2016, Volume: 34, Issue:2

    Topics: Acute Pain; Amines; Anesthesia, Conduction; Chronic Pain; Cyclohexanecarboxylic Acids; Epigenesis, G

2016

Trials

4 trials available for gabapentin and Acute Pain

ArticleYear
Outpatient Treatment With Gabapentin in Women With Severe Acute Pain After Cesarean Delivery Is Ineffective: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Anesthesia and analgesia, 2023, 06-01, Volume: 136, Issue:6

    Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Double-Blind Method; Female; Gabapentin; Humans; Ibup

2023
Factors Associated With Acute Pain Estimation, Postoperative Pain Resolution, Opioid Cessation, and Recovery: Secondary Analysis of a Randomized Clinical Trial.
    JAMA network open, 2019, 03-01, Volume: 2, Issue:3

    Topics: Acute Pain; Aged; Analgesics; Analgesics, Opioid; Double-Blind Method; Female; Gabapentin; Humans; M

2019
Can pregabalin prevent paclitaxel-associated neuropathy?--An ACCRU pilot trial.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016, Volume: 24, Issue:2

    Topics: Acute Pain; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric

2016
Addressing challenges of clinical trials in acute pain: The Pain Management of Vaso-occlusive Crisis in Children and Young Adults with Sickle Cell Disease Study.
    Clinical trials (London, England), 2016, Volume: 13, Issue:4

    Topics: Acute Disease; Acute Pain; Adolescent; Adult; Amines; Analgesics; Anemia, Sickle Cell; Child; Child,

2016

Other Studies

11 other studies available for gabapentin and Acute Pain

ArticleYear
HDAC2 in Primary Sensory Neurons Constitutively Restrains Chronic Pain by Repressing α2δ-1 Expression and Associated NMDA Receptor Activity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022, 11-30, Volume: 42, Issue:48

    Topics: Acute Pain; Animals; Chronic Pain; Female; Gabapentin; Ganglia, Spinal; Histone Deacetylase 2; Histo

2022
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
    Anesthesiology, 2020, Volume: 133, Issue:2

    Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin

2020
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
    Anesthesiology, 2020, Volume: 133, Issue:2

    Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin

2020
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
    Anesthesiology, 2020, Volume: 133, Issue:2

    Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin

2020
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
    Anesthesiology, 2020, Volume: 133, Issue:2

    Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin

2020
Perioperative Use of Gabapentinoids: Comment.
    Anesthesiology, 2021, 04-01, Volume: 134, Issue:4

    Topics: Acute Pain; Gabapentin; Humans; Pain, Postoperative

2021
Perioperative Use of Gabapentinoids: Reply.
    Anesthesiology, 2021, 04-01, Volume: 134, Issue:4

    Topics: Acute Pain; Gabapentin; Humans; Pain, Postoperative

2021
Perioperative Use of Gabapentinoids: Comment.
    Anesthesiology, 2021, 04-01, Volume: 134, Issue:4

    Topics: Acute Pain; Gabapentin; Humans; Pain, Postoperative

2021
Gabapentin to Prevent Acute Pain after Tonsillectomy.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2018, Volume: 158, Issue:5

    Topics: Acute Pain; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; Humans; Tonsillectomy

2018
Response to "Gabapentin to Prevent Acute Pain after Tonsillectomy".
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2018, Volume: 158, Issue:5

    Topics: Acute Pain; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; Humans; Tonsillectomy

2018
Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis.
    Systematic reviews, 2019, 01-16, Volume: 8, Issue:1

    Topics: Acute Pain; Analgesics; Gabapentin; Humans; Meta-Analysis as Topic; Pain, Postoperative; Perioperati

2019
Clinical Pharmacology Considerations in Pain Management in Patients with Advanced Kidney Failure.
    Clinical journal of the American Society of Nephrology : CJASN, 2019, 06-07, Volume: 14, Issue:6

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Chronic Pain

2019
Assessing carrageenan-induced locomotor activity impairment in rats: comparison with evoked endpoint of acute inflammatory pain.
    European journal of pain (London, England), 2012, Volume: 16, Issue:6

    Topics: Acute Pain; Adrenergic Uptake Inhibitors; Amines; Amphetamine; Analgesics; Analgesics, Opioid; Anima

2012
The antinociceptive effects of systemic administration of tramadol, gabapentin and their combination on mice model of acute pain.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2012, Volume: 24, Issue:2

    Topics: Acute Pain; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Mo

2012