gabapentin has been researched along with Acute Pain in 22 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Gabapentin was used as an adjunct for the management of acute pain in approximately half of enhanced recovery programs." | 8.95 | Gabapentin can decrease acute pain and morphine consumption in spinal surgery patients: A meta-analysis of randomized controlled trials. ( Li, C; Peng, C; Qu, J; Wu, D, 2017) |
| " Further studies should determine the optimal dose and whether pregabalin is superior to gabapentin in controlling acute pain after spine surgery." | 8.95 | A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery. ( Liu, B; Liu, R; Wang, L, 2017) |
| "Widely used for acute pain management, the clinical benefit from perioperative use of gabapentinoids is uncertain." | 7.96 | Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis. ( Cossi, MJ; Lauzier, F; Leblanc, G; Neveu, X; Perron, C; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2020) |
| "Our study will provide the best level of evidence to inform the effect of gabapentinoids in the management of postoperative acute pain." | 7.91 | Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis. ( Cossi, MJ; Lauzier, F; Leblanc, G; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2019) |
| "The aim of the present study was to investigate the possible antinociceptive effects of systemic administration of tramadol and gabapentin either alone or in combination on acute pain models in mice." | 7.78 | The antinociceptive effects of systemic administration of tramadol, gabapentin and their combination on mice model of acute pain. ( Alaçam, B; Aydin, ON; Ek, RO; Şen, S; Temoçin, S; Uğur, B, 2012) |
| "Gabapentinoid use has increased substantially in the past several years after initial promising data with regard to acute perioperative pain control." | 6.61 | The role of gabapentinoids in acute and chronic pain after surgery. ( Habib, AS; Kumar, AH, 2019) |
| "It is a novel drug used for the treatment of postoperative pain with antihyperalgesic properties and a unique mechanism of action." | 6.50 | Gabapentin in acute postoperative pain management. ( Challa, CK; Chang, CY; Eloy, JD; Shah, J, 2014) |
| "Paclitaxel can cause an acute pain syndrome (P-APS), considered to be an acute form of neuropathy and chronic chemotherapy-induced peripheral neuropathy (CIPN)." | 5.22 | Can pregabalin prevent paclitaxel-associated neuropathy?--An ACCRU pilot trial. ( Atherton, PJ; Lafky, J; Loprinzi, CL; Pachman, DR; Ruddy, KJ; Seisler, D; Shinde, SS; Soori, G, 2016) |
| " Gabapentin was used as an adjunct for the management of acute pain in approximately half of enhanced recovery programs." | 4.95 | Gabapentin can decrease acute pain and morphine consumption in spinal surgery patients: A meta-analysis of randomized controlled trials. ( Li, C; Peng, C; Qu, J; Wu, D, 2017) |
| " Further studies should determine the optimal dose and whether pregabalin is superior to gabapentin in controlling acute pain after spine surgery." | 4.95 | A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery. ( Liu, B; Liu, R; Wang, L, 2017) |
| "Widely used for acute pain management, the clinical benefit from perioperative use of gabapentinoids is uncertain." | 3.96 | Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis. ( Cossi, MJ; Lauzier, F; Leblanc, G; Neveu, X; Perron, C; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2020) |
| "Our study will provide the best level of evidence to inform the effect of gabapentinoids in the management of postoperative acute pain." | 3.91 | Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis. ( Cossi, MJ; Lauzier, F; Leblanc, G; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2019) |
| "The aim of the present study was to investigate the possible antinociceptive effects of systemic administration of tramadol and gabapentin either alone or in combination on acute pain models in mice." | 3.78 | The antinociceptive effects of systemic administration of tramadol, gabapentin and their combination on mice model of acute pain. ( Alaçam, B; Aydin, ON; Ek, RO; Şen, S; Temoçin, S; Uğur, B, 2012) |
| "Acute postoperative pain is associated with the development of persistent postsurgical pain, but it is unclear which aspect is most estimable." | 2.90 | Factors Associated With Acute Pain Estimation, Postoperative Pain Resolution, Opioid Cessation, and Recovery: Secondary Analysis of a Randomized Clinical Trial. ( Carroll, I; Clay, D; Costouros, JG; Cramer, E; Curtin, C; Dirbas, FM; Goodman, S; Hah, JM; Hilmoe, H; Huddleston, J; Mackey, SC; Maloney, WJ; McCue, R; Ruchelli, G; Schmidt, P; Sharifzadeh, Y; Shrager, J; Trafton, J, 2019) |
| "Trials of acute pain are complicated by the need to obtain consent, to randomize participants expeditiously while optimally treating pain." | 2.82 | Addressing challenges of clinical trials in acute pain: The Pain Management of Vaso-occlusive Crisis in Children and Young Adults with Sickle Cell Disease Study. ( Anghelescu, DL; Cancio, MI; Christensen, R; Faughnan, LG; Hankins, JS; James, DM; Kang, G; Nottage, KA; Richardson, J; Smeltzer, M; Wang, WC, 2016) |
| "Gabapentinoid use has increased substantially in the past several years after initial promising data with regard to acute perioperative pain control." | 2.61 | The role of gabapentinoids in acute and chronic pain after surgery. ( Habib, AS; Kumar, AH, 2019) |
| "It is a novel drug used for the treatment of postoperative pain with antihyperalgesic properties and a unique mechanism of action." | 2.50 | Gabapentin in acute postoperative pain management. ( Challa, CK; Chang, CY; Eloy, JD; Shah, J, 2014) |
| "Recent awareness that chronic pain may occur after childbirth has prompted clinicians and researchers to investigate this topic." | 2.49 | Chronic pain after childbirth. ( Bollag, L; Landau, R; Ortner, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (68.18) | 24.3611 |
| 2020's | 7 (31.82) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Chen, SR | 1 |
| Zhou, MH | 1 |
| Jin, D | 1 |
| Chen, H | 1 |
| Wang, L | 2 |
| DePinho, RA | 1 |
| Pan, HL | 1 |
| Fowler, C | 1 |
| Chu, AW | 1 |
| Guo, N | 1 |
| Ansari, JR | 1 |
| Shafer, SL | 1 |
| Flood, PD | 1 |
| Iturri, F | 1 |
| Valencia, L | 1 |
| Honorato, C | 1 |
| Martínez, A | 1 |
| Valero, R | 1 |
| Fàbregas, N | 1 |
| Verret, M | 3 |
| Lauzier, F | 3 |
| Zarychanski, R | 3 |
| Perron, C | 1 |
| Savard, X | 2 |
| Pinard, AM | 2 |
| Leblanc, G | 2 |
| Cossi, MJ | 2 |
| Neveu, X | 1 |
| Turgeon, AF | 3 |
| Araujo, BLC | 1 |
| Su, PP | 1 |
| Guan, Z | 1 |
| Peng, C | 1 |
| Li, C | 1 |
| Qu, J | 1 |
| Wu, D | 1 |
| Liu, B | 1 |
| Liu, R | 1 |
| Kendall, MC | 1 |
| Castro-Alves, LJ | 1 |
| Sanders, J | 1 |
| Cameron, C | 1 |
| Dawes, P | 1 |
| Hah, JM | 1 |
| Cramer, E | 1 |
| Hilmoe, H | 1 |
| Schmidt, P | 1 |
| McCue, R | 1 |
| Trafton, J | 1 |
| Clay, D | 1 |
| Sharifzadeh, Y | 1 |
| Ruchelli, G | 1 |
| Goodman, S | 1 |
| Huddleston, J | 1 |
| Maloney, WJ | 1 |
| Dirbas, FM | 1 |
| Shrager, J | 1 |
| Costouros, JG | 1 |
| Curtin, C | 1 |
| Mackey, SC | 1 |
| Carroll, I | 1 |
| Davison, SN | 1 |
| Kumar, AH | 1 |
| Habib, AS | 1 |
| Landau, R | 1 |
| Bollag, L | 1 |
| Ortner, C | 1 |
| Chang, CY | 1 |
| Challa, CK | 1 |
| Shah, J | 1 |
| Eloy, JD | 1 |
| Shinde, SS | 1 |
| Seisler, D | 1 |
| Soori, G | 1 |
| Atherton, PJ | 1 |
| Pachman, DR | 1 |
| Lafky, J | 1 |
| Ruddy, KJ | 1 |
| Loprinzi, CL | 1 |
| Nottage, KA | 1 |
| Hankins, JS | 1 |
| Faughnan, LG | 1 |
| James, DM | 1 |
| Richardson, J | 1 |
| Christensen, R | 1 |
| Kang, G | 1 |
| Smeltzer, M | 1 |
| Cancio, MI | 1 |
| Wang, WC | 1 |
| Anghelescu, DL | 1 |
| Badiola, IJ | 1 |
| Zhu, CZ | 1 |
| Mills, CD | 1 |
| Hsieh, GC | 1 |
| Zhong, C | 1 |
| Mikusa, J | 1 |
| Lewis, LG | 1 |
| Gauvin, D | 1 |
| Lee, CH | 1 |
| Decker, MW | 1 |
| Bannon, AW | 1 |
| Rueter, LE | 1 |
| Joshi, SK | 1 |
| Aydin, ON | 1 |
| Ek, RO | 1 |
| Temoçin, S | 1 |
| Uğur, B | 1 |
| Alaçam, B | 1 |
| Şen, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blind Randomized Placebo-Controlled Clinical Trial of Preoperative Gabapentin Prior to Vaginal Apical Suspension Prolapse Procedures[NCT05658887] | Phase 4 | 110 participants (Anticipated) | Interventional | 2023-01-01 | Enrolling by invitation | ||
| Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia With Isobaric Bupivacaine in Patients Undergoing Surgery to Treat Skin and Soft Tissue Tumors of the Lower Limbs[NCT04741880] | Phase 2/Phase 3 | 66 participants (Anticipated) | Interventional | 2021-06-17 | Recruiting | ||
| "Preoperative Gabapentin and Its Effects on Postoperative Analgesia in Patients Undergoing Cosmetic Breast Surgery"[NCT05997355] | 100 participants (Anticipated) | Interventional | 2023-09-01 | Not yet recruiting | |||
| Use of Oral Pregabalin as Preemptive Analgesia in Abdominal Hysterectomy: Evaluation of Postoperative Pain and Opioid Consumption[NCT04495374] | Phase 4 | 58 participants (Actual) | Interventional | 2019-09-02 | Terminated (stopped due to Due to an atypical health scenario caused by the COVID-19 pandemic) | ||
| Stanford Accelerated Recovery Trial (START)[NCT01067144] | Phase 3 | 422 participants (Actual) | Interventional | 2010-05-31 | Terminated (stopped due to Trial met futility stopping point) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Evaluation of the number of intravenous opioid doses used within 24 hours of postoperative abdominal hysterectomy surgery in patients who used pregabalin 300mg or not as preemptive analgesia (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
| Intervention | number of doses (Median) |
|---|---|
| Group P(0) - Placebo | 4 |
| Group P(1) - Pregabalin 300mg | 2 |
• Assess the presence of adverse effects such as nausea and vomiting, itching and dizziness, comparing the intervention group that used pregabalin with the placebo group (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery) and also immediately in the post-anesthetic recovery room
| Intervention | Participants (Count of Participants) |
|---|---|
| Group P(0) - Placebo | 7 |
| Group P(1) - Pregabalin 300mg | 16 |
Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single 300mg dose of pregabalin or placebo as preemptive analgesia, using the McGill pain questionnaire, which consists of 20 word groups , and each group can contain from 2 to 6 descriptive words, these descriptors are placed in an increasing order of magnitude in relation to the intensity. The left of each word has a numerical value in an attempt to represent the intensity of the descriptor. For the analysis of the answers, the total number of words chosen in each subgroup by the patient was used to qualify his pain, the minimum value being equal to 0 (zero), if the patient chose not to choose any descriptor, and the maximum value would be 20, as the patient can choose only one descriptor for each subgroup. The quantitative pain index was also evaluated, which represents the sum of the values of each descriptor chosen by the patient, with a minimum value of 0 and a maximum of 78. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
| Intervention | score on a scale (Median) |
|---|---|
| Group P(0) - Placebo | 28.5 |
| Group P(1) - Pregabalin 300mg | 12 |
Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single dose of pregabalin 300mg or placebo as preemptive analgesia, using the visual analog scale (VAS) consisting of a 10 cm (cm) line ) graduated in natural number intervals, starting at 0 (zero) until reaching 10 (ten), associated with the numbers, drawings related to the pain presented by the patient at the moment, in which the absence of pain (0 ) there is a happy face, and as the numerical value increases, the drawn face will represent the intensity of pain, up to the value of 10, where a face with crying characteristics is found, indicating greater pain. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
| Intervention | score on a scale (Mean) |
|---|---|
| Group P(0) - Placebo | 7 |
| Group P(1) - Pregabalin 300mg | 4 |
Postoperative pain assessment, 24 hours after abdominal hysterectomy surgery, in patients who used a single dose of pregabalin 300mg or placebo as preemptive analgesia, using the visual analog scale (VAS) consisting of a 10 cm (cm) line ) graduated in natural number intervals, starting at 0 (zero) until reaching 10 (ten), associated with the numbers, drawings related to the pain presented by the patient at the moment, in which the absence of pain (0 ) there is a happy face, and as the numerical value increases, the drawn face will represent the intensity of pain, up to the value of 10, where a face with crying characteristics is found, indicating greater pain. (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
| Intervention | score on a scale (Mean) |
|---|---|
| Group P(0) - Placebo | 5 |
| Group P(1) - Pregabalin 300mg | 2 |
• Evaluation of the time between the end of abdominal hysterectomy surgery and the patient's request for the use of the first dose of intravenous opioid as an analgesic rescue, comparing between patients who used or not pregabalin 300mg as preemptive analgesia (NCT04495374)
Timeframe: End of the first postoperative day of abdominal hysterectomy surgery (24 hours after the end of surgery)
| Intervention | Time in minutes (Median) |
|---|---|
| Group P(0) - Placebo | 170 |
| Group P(1) - Pregabalin 300mg | 106 |
Continued opioid use was defined as any report of any continued opioid use at Year 1. (NCT01067144)
Timeframe: Year 1
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 3 |
| Gabapentin | 4 |
Continued opioid use was defined as any report of any continued opioid use at Month 6. (NCT01067144)
Timeframe: Month 6
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 4 |
| Gabapentin | 5 |
"Continued pain was defined as a report of at least 1 average pain at the surgical site (as reported by the patient on a scale of 0-10, with lower scores corresponding to less pain (0 = no pain) and higher scores corresponding to more pain)." (NCT01067144)
Timeframe: Year 1
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 18 |
| Gabapentin | 21 |
"Continued pain was defined as a report of at least 1 average pain at the surgical site (as reported by the patient on a scale of 0-10, with lower scores corresponding to less pain (0 = no pain) and higher scores corresponding to more pain)." (NCT01067144)
Timeframe: Month 6
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 37 |
| Gabapentin | 42 |
Time to opioid cessation was defined as 5 consecutive reports of no opioid use. Planned call frequency was daily for 3 months, weekly thereafter up to 6 months, and monthly thereafter up to 2 years after surgery. (NCT01067144)
Timeframe: Up to 2 years
| Intervention | days (Median) |
|---|---|
| Control | 32 |
| Gabapentin | 25 |
"Time to pain resolution was defined as 5 consecutive reports of 0 average pain at the surgical site (as reported by the patient on a scale of 0-10, with lower scores corresponding to less pain (0 = no pain) and higher scores corresponding to more pain). Planned call frequency was daily for 3 months, weekly thereafter up to 6 months, and monthly thereafter up to 2 years after surgery." (NCT01067144)
Timeframe: Up to 2 years
| Intervention | days (Median) |
|---|---|
| Control | 73 |
| Gabapentin | 84 |
7 reviews available for gabapentin and Acute Pain
| Article | Year |
|---|---|
Narrative review of acute post-craniotomy pain. Concept and strategies for prevention and treatment of pain.
Topics: Acupuncture Analgesia; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory A | 2020 |
Gabapentin can decrease acute pain and morphine consumption in spinal surgery patients: A meta-analysis of randomized controlled trials.
Topics: Acute Pain; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabap | 2017 |
A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery.
Topics: Acute Pain; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hu | 2017 |
The role of gabapentinoids in acute and chronic pain after surgery.
Topics: Acute Pain; Analgesia; Analgesics; Chronic Pain; Enhanced Recovery After Surgery; Gabapentin; Humans | 2019 |
Chronic pain after childbirth.
Topics: Acute Pain; Adrenergic alpha-Agonists; Adult; Amines; Analgesics; Anesthetics, Dissociative; Cesarea | 2013 |
Gabapentin in acute postoperative pain management.
Topics: Acute Pain; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric | 2014 |
Can Chronic Pain Be Prevented?
Topics: Acute Pain; Amines; Anesthesia, Conduction; Chronic Pain; Cyclohexanecarboxylic Acids; Epigenesis, G | 2016 |
4 trials available for gabapentin and Acute Pain
| Article | Year |
|---|---|
Outpatient Treatment With Gabapentin in Women With Severe Acute Pain After Cesarean Delivery Is Ineffective: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Double-Blind Method; Female; Gabapentin; Humans; Ibup | 2023 |
Factors Associated With Acute Pain Estimation, Postoperative Pain Resolution, Opioid Cessation, and Recovery: Secondary Analysis of a Randomized Clinical Trial.
Topics: Acute Pain; Aged; Analgesics; Analgesics, Opioid; Double-Blind Method; Female; Gabapentin; Humans; M | 2019 |
Can pregabalin prevent paclitaxel-associated neuropathy?--An ACCRU pilot trial.
Topics: Acute Pain; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric | 2016 |
Addressing challenges of clinical trials in acute pain: The Pain Management of Vaso-occlusive Crisis in Children and Young Adults with Sickle Cell Disease Study.
Topics: Acute Disease; Acute Pain; Adolescent; Adult; Amines; Analgesics; Anemia, Sickle Cell; Child; Child, | 2016 |
11 other studies available for gabapentin and Acute Pain
| Article | Year |
|---|---|
HDAC2 in Primary Sensory Neurons Constitutively Restrains Chronic Pain by Repressing α2δ-1 Expression and Associated NMDA Receptor Activity.
Topics: Acute Pain; Animals; Chronic Pain; Female; Gabapentin; Ganglia, Spinal; Histone Deacetylase 2; Histo | 2022 |
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin | 2020 |
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin | 2020 |
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin | 2020 |
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin | 2020 |
Perioperative Use of Gabapentinoids: Comment.
Topics: Acute Pain; Gabapentin; Humans; Pain, Postoperative | 2021 |
Perioperative Use of Gabapentinoids: Reply.
Topics: Acute Pain; Gabapentin; Humans; Pain, Postoperative | 2021 |
Perioperative Use of Gabapentinoids: Comment.
Topics: Acute Pain; Gabapentin; Humans; Pain, Postoperative | 2021 |
Gabapentin to Prevent Acute Pain after Tonsillectomy.
Topics: Acute Pain; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; Humans; Tonsillectomy | 2018 |
Response to "Gabapentin to Prevent Acute Pain after Tonsillectomy".
Topics: Acute Pain; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; Humans; Tonsillectomy | 2018 |
Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis.
Topics: Acute Pain; Analgesics; Gabapentin; Humans; Meta-Analysis as Topic; Pain, Postoperative; Perioperati | 2019 |
Clinical Pharmacology Considerations in Pain Management in Patients with Advanced Kidney Failure.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Chronic Pain | 2019 |
Assessing carrageenan-induced locomotor activity impairment in rats: comparison with evoked endpoint of acute inflammatory pain.
Topics: Acute Pain; Adrenergic Uptake Inhibitors; Amines; Amphetamine; Analgesics; Analgesics, Opioid; Anima | 2012 |
The antinociceptive effects of systemic administration of tramadol, gabapentin and their combination on mice model of acute pain.
Topics: Acute Pain; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Mo | 2012 |