gabapentin has been researched along with Acute Liver Injury, Drug-Induced in 13 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
Excerpt | Relevance | Reference |
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"Gabapentin is an anticonvulsant medication used as an adjuvant in the treatment of neuropathic pain; few cases have been reported in which it causes acute liver injury." | 1.62 | [Hepatotoxicity probably associated with gabapentin]. ( Contreras-Mota, M; Rosales-Cortés, V, 2021) |
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (38.46) | 29.6817 |
2010's | 6 (46.15) | 24.3611 |
2020's | 2 (15.38) | 2.80 |
Authors | Studies |
---|---|
Greene, N | 1 |
Fisk, L | 1 |
Naven, RT | 1 |
Note, RR | 1 |
Patel, ML | 1 |
Pelletier, DJ | 1 |
Ekins, S | 1 |
Williams, AJ | 1 |
Xu, JJ | 1 |
Liu, Z | 1 |
Shi, Q | 1 |
Ding, D | 1 |
Kelly, R | 1 |
Fang, H | 1 |
Tong, W | 2 |
Warner, DJ | 1 |
Chen, H | 1 |
Cantin, LD | 1 |
Kenna, JG | 1 |
Stahl, S | 1 |
Walker, CL | 1 |
Noeske, T | 1 |
Chen, M | 1 |
Suzuki, A | 1 |
Thakkar, S | 1 |
Yu, K | 1 |
Hu, C | 1 |
Chalasani, N | 1 |
Bonkovsky, HL | 1 |
Stine, JG | 1 |
Gu, J | 1 |
Barnhart, H | 1 |
Jacobsen, E | 1 |
Björnsson, E | 1 |
Fontana, RJ | 1 |
Kleiner, DE | 1 |
Hoofnagle, JH | 1 |
Contreras-Mota, M | 1 |
Rosales-Cortés, V | 1 |
Crespo Pérez, L | 1 |
Moreira Vicente, V | 1 |
Cano Ruiz, A | 1 |
Gobernado Serrano, JM | 1 |
Cobo Ibañez, N | 1 |
Milicua Salamero, JM | 1 |
Hauben, M | 1 |
Bureau, C | 1 |
Poirson, H | 1 |
Péron, JM | 1 |
Vinel, JP | 1 |
Himmerich, H | 1 |
Nickel, T | 1 |
Dalal, MA | 1 |
Müller, MB | 1 |
Lasso-de-la-Vega, MC | 1 |
Zapater, P | 1 |
Such, J | 1 |
Pérez-Mateo, M | 1 |
Horga, JF | 1 |
2 reviews available for gabapentin and Acute Liver Injury, Drug-Induced
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; | 2009 |
11 other studies available for gabapentin and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Clinical characteristics of antiepileptic-induced liver injury in patients from the DILIN prospective study.
Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Chemical and Drug Ind | 2022 |
[Hepatotoxicity probably associated with gabapentin].
Topics: Amines; Analgesics; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Gabapentin; | 2021 |
Gabapentin and pregabalin: hepatic and haematological toxicity.
Topics: Amines; Analgesics; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; France; Gab | 2014 |
Re: Lasso-de-la-Vega et al. gabapentin as a probable cause of hepatotoxicity and eosinophilia.
Topics: Acetates; Amines; Analgesics; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Ciprofl | 2002 |
[Gabapentine-induced acute hepatitis].
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cyclohexan | 2003 |
[Gabapentin treatment in a female patient with panic disorder and adverse effects under carbamazepine during benzodiazepine withdrawal].
Topics: Aged; Alprazolam; Amines; Antimanic Agents; Benzodiazepines; Carbamazepine; Chemical and Drug Induce | 2007 |
Gabapentin-associated hepatotoxicity.
Topics: Acetates; Amines; Analgesics; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; G | 2001 |