Page last updated: 2024-10-27

gabapentin and Acute Disease

gabapentin has been researched along with Acute Disease in 57 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"Topiramate appears to show promise as an addition to the agents available to treat bipolar disorder."10.19The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder. ( Chengappa, KN; Gershon, S; Levine, J, 2001)
"This randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster."9.11A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster. ( Berry, JD; Petersen, KL, 2005)
"There is evidence to show that gabapentin is effective in neuropathic pain."8.82Gabapentin for acute and chronic pain. ( Edwards, JE; McQuay, HJ; Moore, RA; Wiffen, PJ, 2005)
"To evaluate the efficacy of treatment with gabapentin plus valacyclovir hydrochloride for the prevention of postherpetic neuralgia in patients with acute herpes zoster."7.77Incidence of postherpetic neuralgia after combination treatment with gabapentin and valacyclovir in patients with acute herpes zoster: open-label study. ( Digiorgio, C; Grady, J; Haitz, K; Lapolla, W; Lu, W; Magel, G; Mendoza, N; Tyring, S, 2011)
"The anticonvulsant gabapentin (GBP) has been shown effective for the treatment of neuropathic pain, although its mechanism of action remains unclear."7.73Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action. ( Aiyar, J; Anker, N; Belley, M; Bristow, L; Campbell, B; Cohen, C; Park, KT; Ren, K; Stearns, B; Urban, MO, 2005)
"Combined spinal administration of gabapentin and low doses of morphine significantly reduces pain-related behaviors in this acute rat pancreatitis model, whereas these agents were ineffective when used alone in this dose range."7.72Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model. ( Lu, Y; Smiley, MM; Vera-Portocarrero, LP; Westlund, KN; Zidan, A, 2004)
"To present two years of experience in the use of gabapentin for the alleviation of neuropathic pain in spinal cord injury patients."7.71Gabapentin for neuropathic pain following spinal cord injury. ( Brown, DJ; Cooper, N; Frauman, AG; Hill, ST; Kirsa, SW; Lim, TC; To, TP, 2002)
"This report describes the results of maintenance treatment with gabapentin in 18 previously refractory Bipolar Disorder patients who initially responded to augmentation with gabapentin during the acute phase of their therapy."7.70Open maintenance treatment of bipolar disorder spectrum patients who responded to gabapentin augmentation in the acute phase of treatment. ( Schaffer, CB; Schaffer, LC, 1999)
"Gabapentin was well tolerated by all patients, with the most common side-effect being sedation."6.69Gabapentin in the acute treatment of refractory bipolar disorder. ( Altshuler, LL; Brown, ES; Denicoff, K; Frye, M; Gitlin, M; Goodman, R; Hwang, S; Keck, PE; Kupka, R; Leverich, G; McElroy, SL; Nolen, W; Post, R; Suppes, T, 1999)
"Its efficacy in treating established acute postoperative pain has not been demonstrated."6.46Single dose oral gabapentin for established acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA; Straube, S; Wiffen, PJ, 2010)
"Topiramate appears to show promise as an addition to the agents available to treat bipolar disorder."6.19The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder. ( Chengappa, KN; Gershon, S; Levine, J, 2001)
"Seizures were detected by continuous electroencephalographic monitoring for 24 h following permanent middle cerebral artery occlusion (MCAo)."5.33Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats. ( Bautista, CC; Chen, RW; Dave, JR; Hartings, JA; Lu, XC; Tortella, FC; Williams, AJ, 2006)
"In this clinical trial, we studied the effects of adjunctive treatment with gabapentin in controlling the symptoms of acute mania in patients admitted with bipolar disorder."5.16Adjunctive treatment with gabapentin in bipolar patients during acute mania. ( Astaneh, AN; Rezaei, O, 2012)
"The purpose of this study was to evaluate the analgesic effects of perioperative gabapentin on postoperative acute and chronic pain after coronary artery bypass graft (CABG) surgery with median sternotomy and internal mammary artery harvesting."5.15The effects of gabapentin on acute and chronic postoperative pain after coronary artery bypass graft surgery. ( Onan, B; Selcuk, I; Sen, H; Turan, A; Ucak, A; Yilmaz, AT, 2011)
" Up to estimated 336 patients (interim analyses) with acute herpes zoster pain (VAS > 30 mm) will be randomised to one of three groups (a) semi-standardised acupuncture (168 patients); (b) gabapentine with individualised dosage between 900-3600 mg/d (84 patients); (c) sham laser acupuncture."5.14Acupuncture in acute herpes zoster pain therapy (ACUZoster) - design and protocol of a randomised controlled trial. ( Fleckenstein, J; Hoffrogge, P; Irnich, D; Kramer, S; Lang, PM; Lehmeyer, L; Mansmann, U; Pfab, F; Ring, J; Schober, GM; Schotten, KJ; Thoma, S; Weisenseel, P, 2009)
"This randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster."5.11A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster. ( Berry, JD; Petersen, KL, 2005)
" Fifty patients scheduled for breast cancer surgery were blindly randomized to receive gabapentin, eutectic mixture of local anesthetics cream, and ropivacaine in the wound or three placebos."5.11Multimodal analgesia with gabapentin and local anesthetics prevents acute and chronic pain after breast surgery for cancer. ( Fassoulaki, A; Melemeni, A; Sarantopoulos, C; Triga, A, 2005)
"There is evidence to show that gabapentin is effective in neuropathic pain."4.82Gabapentin for acute and chronic pain. ( Edwards, JE; McQuay, HJ; Moore, RA; Wiffen, PJ, 2005)
"To evaluate the efficacy of treatment with gabapentin plus valacyclovir hydrochloride for the prevention of postherpetic neuralgia in patients with acute herpes zoster."3.77Incidence of postherpetic neuralgia after combination treatment with gabapentin and valacyclovir in patients with acute herpes zoster: open-label study. ( Digiorgio, C; Grady, J; Haitz, K; Lapolla, W; Lu, W; Magel, G; Mendoza, N; Tyring, S, 2011)
"The anticonvulsant gabapentin (GBP) has been shown effective for the treatment of neuropathic pain, although its mechanism of action remains unclear."3.73Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action. ( Aiyar, J; Anker, N; Belley, M; Bristow, L; Campbell, B; Cohen, C; Park, KT; Ren, K; Stearns, B; Urban, MO, 2005)
"Combined spinal administration of gabapentin and low doses of morphine significantly reduces pain-related behaviors in this acute rat pancreatitis model, whereas these agents were ineffective when used alone in this dose range."3.72Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model. ( Lu, Y; Smiley, MM; Vera-Portocarrero, LP; Westlund, KN; Zidan, A, 2004)
"To present two years of experience in the use of gabapentin for the alleviation of neuropathic pain in spinal cord injury patients."3.71Gabapentin for neuropathic pain following spinal cord injury. ( Brown, DJ; Cooper, N; Frauman, AG; Hill, ST; Kirsa, SW; Lim, TC; To, TP, 2002)
"This report describes the results of maintenance treatment with gabapentin in 18 previously refractory Bipolar Disorder patients who initially responded to augmentation with gabapentin during the acute phase of their therapy."3.70Open maintenance treatment of bipolar disorder spectrum patients who responded to gabapentin augmentation in the acute phase of treatment. ( Schaffer, CB; Schaffer, LC, 1999)
"The novel anti-epileptic drugs lamotrigine, felbamate and gabapentin were compared in rat experimental models of acute (tail flick) and chronic pain: the chronic constriction injury and spinal nerve ligation models."3.69The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain. ( Fontana, DJ; Gogas, KR; Hedley, LR; Hunter, JC; Jacobson, LO; Kassotakis, L; Thompson, J, 1997)
"Trials of acute pain are complicated by the need to obtain consent, to randomize participants expeditiously while optimally treating pain."2.82Addressing challenges of clinical trials in acute pain: The Pain Management of Vaso-occlusive Crisis in Children and Young Adults with Sickle Cell Disease Study. ( Anghelescu, DL; Cancio, MI; Christensen, R; Faughnan, LG; Hankins, JS; James, DM; Kang, G; Nottage, KA; Richardson, J; Smeltzer, M; Wang, WC, 2016)
"Gabapentin has opioid-sparing effects in adult surgical patients, but no reported studies have involved children and adolescents."2.75Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial. ( Berens, RJ; Czarnecki, ML; Hainsworth, KR; Lyon, RM; Nelson, TJ; Rusy, LM; Tassone, JC; Thometz, JG; Weisman, SJ, 2010)
"Gabapentin was effective in the treatment of mania and hypomania in patients with bipolar and schizoaffective disorders."2.69Clinical experience with gabapentin in patients with bipolar or schizoaffective disorder: results of an open-label study. ( Cabras, PL; Carta, MG; Hardoy, MC; Hardoy, MJ, 1999)
"Gabapentin was well tolerated by all patients, with the most common side-effect being sedation."2.69Gabapentin in the acute treatment of refractory bipolar disorder. ( Altshuler, LL; Brown, ES; Denicoff, K; Frye, M; Gitlin, M; Goodman, R; Hwang, S; Keck, PE; Kupka, R; Leverich, G; McElroy, SL; Nolen, W; Post, R; Suppes, T, 1999)
"Its efficacy in treating established acute postoperative pain has not been demonstrated."2.46Single dose oral gabapentin for established acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA; Straube, S; Wiffen, PJ, 2010)
"There is a general agreement now that migraine is not only a vascular phenomenon but also a genetically determined heterogenic ion-channelopathy resulting in cortical-spreading-depression-like events, the temporary impairment of antinociceptive structures of the brainstem and the activation of the trigeminal-vascular system."2.44GABAergic drugs for the treatment of migraine. ( Limmroth, V; Puppe, A, 2007)
"When gabapentin was administered at doses less than 1200 mg, pain intensity was also lower at 6 h (WMD, -22."2.43Gabapentin and postoperative pain--a systematic review of randomized controlled trials. ( Gan, TJ; Habib, AS; Ho, KY, 2006)
"Migraine and headache studies are excluded in this revision."2.43Anticonvulsant drugs for acute and chronic pain. ( Carroll, D; Collins, S; Jadad, A; McQuay, H; Moore, A; Wiffen, P, 2005)
"Inhibition of herpetic allodynia by repeated oral administration of gabapentin (100 mg/kg) alleviated the overexpression of mRNA of pronociceptin, as well as the severity of postherpetic allodynia."1.35Nociceptin-receptor deficiency prevents postherpetic pain without effects on acute herpetic pain in mice. ( Andoh, T; Kuraishi, Y; Sasaki, A; Shiraki, K; Takahata, H; Takasaki, I; Takeshima, H, 2008)
"Transverse myelitis is a group of disorders characterized by focal inflammation of the spinal cord and results in loss of motor and sensory function below the level of injury."1.34Transverse myelitis caused by varicella zoster: case reports. ( Köseolu, HK; Yücel, E; Yýlmaz, S, 2007)
"Acute chest pain is a common presentation in emergency."1.34Role of Stellate ganglion block in post CABG sympathetically mediated chest pain. ( Ahmed, I; Khan, MU, 2007)
"Seizures were detected by continuous electroencephalographic monitoring for 24 h following permanent middle cerebral artery occlusion (MCAo)."1.33Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats. ( Bautista, CC; Chen, RW; Dave, JR; Hartings, JA; Lu, XC; Tortella, FC; Williams, AJ, 2006)
"Acyclovir treatment healed all skin lesions by day 15 after inoculation."1.31Effects of analgesics on delayed postherpetic pain in mice. ( Andoh, T; Kuraishi, Y; Nojima, H; Sasaki, A; Shiraki, K; Takasaki, I, 2002)

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (14.04)18.2507
2000's34 (59.65)29.6817
2010's15 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Simancas-Racines, D1
Arevalo-Rodriguez, I1
Osorio, D1
Franco, JV1
Xu, Y1
Hidalgo, R1
Morrison, M1
Udeh, E1
Burak, M1
Sadler, KE1
Langer, SN1
Menzel, AD1
Moehring, F1
Erb, AN1
Brandow, AM1
Stucky, CL1
Browne, MJ1
Zakrzewski, H1
Carleton, B1
Etminan, M1
Mikelberg, FS1
Rohman, L1
Hebron, A1
Zhao, M1
Nakamura, S1
Miyake, T1
So, K1
Shirakawa, H1
Tokuyama, S1
Narita, M1
Nakagawa, T1
Kaneko, S1
Dias, JM1
de Brito, TV1
de Aguiar Magalhães, D1
da Silva Santos, PW1
Batista, JA1
do Nascimento Dias, EG1
de Barros Fernandes, H1
Damasceno, SR1
Silva, RO1
Aragão, KS1
Souza, MH1
Medeiros, JV1
Barbosa, AL1
Matsumura, S1
Taniguchi, W1
Nishida, K1
Nakatsuka, T1
Ito, S1
Nottage, KA1
Hankins, JS1
Faughnan, LG1
James, DM1
Richardson, J1
Christensen, R1
Kang, G1
Smeltzer, M1
Cancio, MI1
Wang, WC1
Anghelescu, DL1
Dworkin, RH1
Barbano, RL1
Tyring, SK1
Betts, RF1
McDermott, MP1
Pennella-Vaughan, J1
Bennett, GJ1
Berber, E1
Gnann, JW1
Irvine, C1
Kamp, C1
Kieburtz, K1
Max, MB1
Schmader, KE1
Clarke, H1
Pereira, S1
Kennedy, D1
Andrion, J1
Mitsakakis, N1
Gollish, J1
Katz, J1
Kay, J1
Fleckenstein, J1
Kramer, S1
Hoffrogge, P1
Thoma, S1
Lang, PM1
Lehmeyer, L1
Schober, GM1
Pfab, F1
Ring, J1
Weisenseel, P1
Schotten, KJ1
Mansmann, U1
Irnich, D1
Sen, H2
Sizlan, A1
Yanarates, O1
Emirkadi, H1
Ozkan, S1
Dagli, G1
Turan, A3
Rusy, LM1
Hainsworth, KR1
Nelson, TJ1
Czarnecki, ML1
Tassone, JC1
Thometz, JG1
Lyon, RM1
Berens, RJ1
Weisman, SJ1
Straube, S1
Derry, S2
Moore, RA3
Wiffen, PJ2
McQuay, HJ3
Amr, YM1
Yousef, AA1
Ucak, A1
Onan, B1
Selcuk, I1
Yilmaz, AT1
Lapolla, W1
Digiorgio, C1
Haitz, K1
Magel, G1
Mendoza, N1
Grady, J1
Lu, W1
Tyring, S1
Astaneh, AN1
Rezaei, O1
Laughlin, TM1
Tram, KV1
Wilcox, GL1
Birnbaum, AK1
Bureau, C1
Poirson, H1
Péron, JM1
Vinel, JP1
Dost, R1
Rostock, A1
Rundfeldt, C1
Karamanlioğlu, B1
Memiş, D1
Hamamcioglu, MK1
Tükenmez, B1
Pamukçu, Z1
Kurt, I1
French, JA1
Kanner, AM1
Bautista, J1
Abou-Khalil, B1
Browne, T1
Harden, CL1
Theodore, WH1
Bazil, C1
Stern, J1
Schachter, SC1
Bergen, D1
Hirtz, D1
Montouris, GD1
Nespeca, M1
Gidal, B1
Marks, WJ1
Turk, WR1
Fischer, JH1
Bourgeois, B1
Wilner, A1
Faught, RE1
Sachdeo, RC1
Beydoun, A1
Glauser, TA1
Iyengar, S1
Webster, AA1
Hemrick-Luecke, SK1
Xu, JY1
Simmons, RM1
Smiley, MM1
Lu, Y1
Vera-Portocarrero, LP1
Zidan, A1
Westlund, KN1
Urban, MO1
Ren, K1
Park, KT1
Campbell, B1
Anker, N1
Stearns, B1
Aiyar, J1
Belley, M1
Cohen, C1
Bristow, L1
Muzina, DJ1
Elhaj, O1
Gajwani, P1
Gao, K1
Calabrese, JR1
Wiffen, P1
Collins, S1
McQuay, H1
Carroll, D1
Jadad, A1
Moore, A1
Edwards, JE1
Berry, JD1
Petersen, KL1
Fassoulaki, A1
Triga, A1
Melemeni, A1
Sarantopoulos, C1
Williams, AJ1
Bautista, CC1
Chen, RW1
Dave, JR1
Lu, XC1
Tortella, FC1
Hartings, JA1
Ho, KY1
Gan, TJ1
Habib, AS1
Moulin, D1
Yýlmaz, S1
Köseolu, HK1
Yücel, E1
Striano, P1
Coppola, A1
Madia, F1
Pezzella, M1
Ciampa, C1
Zara, F1
Striano, S1
Puppe, A1
Limmroth, V1
Niscola, P1
Perrotti, AP1
del Poeta, G1
Romani, C1
Palombi, M1
Piccioni, D1
Scaramucci, L1
Tolu, B1
Tendas, A1
Cupelli, L1
Abruzzese, E1
D'Elia, GM1
Brunetti, GA1
Maurillo, L1
Giovannini, M1
Cartoni, C1
de Fabritiis, P1
Khan, MU1
Ahmed, I1
Ketz, AK1
Sasaki, A2
Takasaki, I2
Andoh, T2
Shiraki, K2
Takeshima, H1
Takahata, H1
Kuraishi, Y2
Poon, KH1
Stanton, SP1
Keck, PE2
McElroy, SL2
Hunter, JC1
Gogas, KR1
Hedley, LR1
Jacobson, LO1
Kassotakis, L1
Thompson, J1
Fontana, DJ1
Young, LT1
Robb, JC1
Patelis-Siotis, I1
MacDonald, C1
Joffe, RT1
Elger, CE1
Bauer, J1
Scherrmann, J1
Widman, G1
Hatzimanolis, J1
Lykouras, L1
Oulis, P1
Christodoulou, GN1
Cabras, PL1
Hardoy, MJ1
Hardoy, MC1
Carta, MG1
Schaffer, CB1
Schaffer, LC1
Porta-Etessam, J1
García-Morales, I1
Martínez-Salio, A1
Berbel, A1
Benito-León, J1
Gallay, BJ1
de Mattos, AM1
Norman, DJ1
Carver, A1
Payne, R1
Foley, K1
Altshuler, LL1
Suppes, T1
Brown, ES1
Denicoff, K1
Frye, M1
Gitlin, M1
Hwang, S1
Goodman, R1
Leverich, G1
Nolen, W1
Kupka, R1
Post, R1
Chengappa, KN1
Gershon, S1
Levine, J1
Nojima, H1
To, TP1
Lim, TC1
Hill, ST1
Frauman, AG1
Cooper, N1
Kirsa, SW1
Brown, DJ1

Clinical Trials (22)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Early Use of Oxycodone During the Acute Phase of Herpes Zoster on Preventing Postherpetic Neuralgia[NCT03120962]140 participants (Anticipated)Interventional2017-05-31Not yet recruiting
Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain: A Multicenter Prospective Study[NCT04798573]10,000 participants (Anticipated)Observational2012-08-03Active, not recruiting
Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543]90 participants (Actual)Interventional2014-06-30Completed
Analgetic Effectiveness of Acupuncture When Compared to a Standardised Analgesic Regimen in the Treatment of Herpes Zoster Neuralgia[NCT00885586]Phase 468 participants (Actual)Interventional2008-11-30Completed
The Efficacy and Safety of Intradermal Acupuncture for Acute Herpes Zoster: Study Protocol for a Randomized Controlled Trial[NCT05348382]72 participants (Anticipated)Interventional2022-07-04Recruiting
The Effect of Intravenous Infusions of Lidocaine and Magnesium Versus Lidocaine and Ketamine Versus Lidocaine Alone on Recovery Profile and Postoperative Pain After Elective Gynecological Surgery[NCT04622904]90 participants (Anticipated)Interventional2020-11-14Recruiting
Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia[NCT03066739]Phase 2105 participants (Anticipated)Interventional2023-02-25Recruiting
Use of Gabapentin as Preanesthetic Medication in Oncologic Children Undergoing in Fast Procedures With Sevofluran[NCT03681574]Phase 4135 participants (Actual)Interventional2017-07-01Completed
Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients[NCT02558010]Phase 358 participants (Actual)Interventional2016-02-01Completed
Placebo Controlled, Randomized,Gabapentin as Adjuvant for Postoperative Pain in Pediatric Orthopedic Surgery[NCT03005483]Phase 440 participants (Actual)Interventional2014-01-31Completed
Gabapentin Regimens and Their Effects on Opioid Consumption[NCT03334903]Phase 477 participants (Actual)Interventional2018-05-15Completed
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin on Post-operative Opioid Use and Patient Satisfaction[NCT01977937]Phase 455 participants (Actual)Interventional2013-11-30Completed
Efficacy of Gabapentin as Adjuvant for Postoperative Pain in Pediatric Thoracic Surgery - a Randomized Quadruple Blind Study[NCT03393702]Phase 4104 participants (Actual)Interventional2017-05-09Completed
Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management[NCT02703259]Phase 4137 participants (Actual)Interventional2016-06-30Completed
The Effect of Lidocaine to Prevent the Development of Chronic Post-Surgical Pain[NCT01619852]148 participants (Actual)Interventional2012-06-30Completed
[NCT01250561]133 participants (Actual)Interventional2002-02-28Completed
Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187]8 participants (Actual)Interventional2009-11-30Terminated (stopped due to PI left institution)
Randomized Controlled Pilot Trial of Adjunct Group Acupuncture vs Usual Care Among Patients With Painful Diabetic Neuropathy[NCT02104466]40 participants (Actual)Interventional2015-03-31Completed
Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients[NCT02160301]Phase 40 participants (Actual)Interventional2017-11-30Withdrawn (stopped due to Insufficient infrastructure/funding for enrollment)
The Effect of Gabapentin on Acute Pain and PONV in Bariatric Surgical Patients[NCT00886236]62 participants (Actual)Interventional2008-02-29Completed
Comparison of Oral Lamotrigine Versus Pregabalin for Control of Acute and Chronic Pain Following Modified Radical Mastectomy: Controlled Double-blind Study[NCT03419949]0 participants Expanded AccessAvailable
Pilot Evaluation of Levetiracetam (Keppra® (Registered Trademark)) in Bipolar Illness[NCT00015769]Phase 230 participants Interventional2001-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Post-operative Opioid Consumption (mg/kg)

Total amount of opioids consumed during the first 72 hours after surgery. (NCT02558010)
Timeframe: 72 hours

Interventionmg/kg (Median)
Methadone Group0.267
Control Group0.340

"VAS Score 1: How Much Pain do You Feel in Your Operative Site When Resting?"

Surgical site pain. Scale 0-10, with 0 best and 10 worst (NCT03334903)
Timeframe: 2-3 months after surgery (at 2nd postoperative appointment)

Interventionscore on 10-point scale (Mean)
Standard of Care2.26
Postoperative Gabapentin Regimen2.46

"VAS Score 2: How Much Pain do You Feel in Your Operative Site When Moving?"

Surgical site pain. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care3.84
Postoperative Gabapentin Regimen3.54

"VAS Score 3: How Well Are You Sleeping?"

Sleep quality. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care5.73
Postoperative Gabapentin Regimen6.38

"VAS Score 4: How Bad is Your Nausea?"

Nausea. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care0.36
Postoperative Gabapentin Regimen0.17

"VAS Score 5: How Satisfied Are You With Your Pain Management?"

Satisfaction. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventionscore on a 10-point scale (Mean)
Standard of Care7.83
Postoperative Gabapentin Regimen8.48

Days Taking Opioids

Number of days until patients are finished consuming opioid medications after discharge. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).

Interventiondays (Mean)
Standard of Care14.8
Postoperative Gabapentin Regimen18.7

Opioid Consumption

Mean opioid consumption, measured in mg of morphine equivalents. (NCT03334903)
Timeframe: 2-3 months following surgery (total amount measured at second postoperative appointment; means assessed afterwards).

Interventionmorphine equivalents (Mean)
Standard of Care287.0
Postoperative Gabapentin Regimen281.1

Difference in Pain Control When Adding Gabapentin to a Multimodal Pain Management Protocol in Pediatric Post-operative Posterior Spinal Fusion Patients.

"Patients will rate their pain using the Visual Analog Pain Scale (VAS). The VAS is a 10 cm line with anchors of no pain and worst pain imaginable. Patients rate their pain by marking on the 10 cm line where they feel their pain is at the time. The mark is then measured according to where it is along the 10 cm line and reported (range is 0.0 at the no pain end on the left up to 10.0 at the worst pain imaginable on the right). Lower pain scores on the VAS scale are considered a better outcome. The numbers seen in the outcome measure data table below represent an average of the total postoperative VAS scores recorded for each patient from each arm for the duration of their hospital stay." (NCT01977937)
Timeframe: five days

Interventionpain score on a scale (Mean)
Gabapentin2.46
Simple Syrup3.46

Opiate Usage in the Gabapentin Group Versus Control.

Total the amount of Hydromorphone and Oxycodone used in milligrams per kilogram in each patient post-operatively, convert this amount to morphine equivalents, and determine if there is a significant difference between the Gabapentin versus Placebo group. (NCT01977937)
Timeframe: Five Days

Interventionmorphine equivalents mg per kg (Mean)
Gabapentin3.58
Simple Syrup5.33

Narcotic Use at 2 Weeks Postop

Assessment of the amount of narcotic use postoperatively at 2 weeks. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents (NCT02703259)
Timeframe: 2 weeks

Interventionmorphine milligram equivalents (Mean)
Gabapentin167.2
Control187.3

Narcotic Use at 24 Hours Postop

Assessment of the amount of narcotic use postoperatively at 24 hours. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents (NCT02703259)
Timeframe: 24 hours

Interventionmorphine milligram equivalents (Mean)
Gabapentin158.8
Control175.0

Subjective Pain at 2 Weeks Postop

"Assessment of the subject pain score postoperatively at 2 weeks. will use a numeric analog scale from 0-10.~The pain scale ranging from 0-10 with 0 representing No Pain and 10 representing the Worst Pain Possible" (NCT02703259)
Timeframe: 2 weeks

Interventionscore on a scale (Mean)
Gabapentin1.3
Control1.4

Subjective Pain at 24 Hours Postoperative

Pain score assesses patient subjective pain via patient reported numeric analogue scale, range 0-10 with 0 being no pain and 10 being severe pain. (NCT02703259)
Timeframe: 24 hours

Interventionscore on a scale (Mean)
Gabapentin3.4
Control3.4

Number of Patient With Gabapentin Adverse Effects at 2 Weeks Postoperatively

Will assess for known symptoms of gabapentin postoperatively at 2 weeks. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction (NCT02703259)
Timeframe: 2 weeks

,
InterventionParticipants (Count of Participants)
DizzinessBlurred visionSomnolenceDifficulty walkingTremulousnessNauseaVomiting
Control83215271
Gabapentin1241854120

Number of Patient With Gabapentin Adverse Effects at 24 Hours Postoperatively

Will assess for known symptoms of gabapentin postoperatively at 24 hours. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction (NCT02703259)
Timeframe: 24 hours

,
InterventionParticipants (Count of Participants)
DizzinessBlurred VisionSomnolenceDifficulty walkingTremulousnessNauseaVomiting
Control84231162515
Gabapentin177201311249

Number of Participants With Chronic Persistent Pain 3 Months After Surgery as Determined by Character Severity (Yes/no).

The participants development of chronic persistent pain 3 months after surgery as determined by character severity (yes/no). (NCT01619852)
Timeframe: 3 months

Interventionparticipants (Number)
Group L2
.9% Normal Saline Placebo6

Opioid Consumption

The amount of opioid analgesics consumed was converted to an equivalent dose of intravenous morphine. (NCT01619852)
Timeframe: 24 hours

Interventionequivalent dose of intravenous morphine (Median)
Group L34
.9% Normal Saline Placebo39

Postoperative Pain

Postoperative pain within the first 24 hours. Area under the numeric rating scale for pain versus time curve during the first 24 hours after surgery (score * hr). Numeric rating scale for pain on a scale of 0-10 (0 is no pain and 10 is high pain) versus time curve during the first 24 hours ( score * hr). The pain scores were collected upon arrival to recovery area, 30 minutes, 1 hour and every 6 hours up to 24 hours following the procedure. Minimum score is 60, Maximum score is 170. A higher value indicates more pain. (NCT01619852)
Timeframe: 24 hours

Interventionscore on a scale (Median)
Group L116
.9% Normal Saline Placebo119

Quality of Recovery

Quality of recovery (QoR-40 instrument) is a 40-item questionnaire that provides a global score and sub-scores across five dimensions: patient support, comfort, emotions, physical independence, and pain. Score range: 40 to 200. A score of 40 demonstrates poor recovery and a maximum score of 200 represents good recovery. The higher the score the better recovery after surgery. (NCT01619852)
Timeframe: 24 hours post operative

Interventionunits on a scale (Median)
Lidocaine (Group L)158
.9% Normal Saline Placebo169

Post-surgical Persistent Pain Using Validated Questionnaires (S-LANNS Questionnaire, McGill Questionnaire, Brief Pain Inventory) to Assess Pain Qualities in Accordance With IMMPACT Recommendations.

The development of chronic pain 3 months after surgery determined by the Leads Assessment of Neuropathic Symptoms and Signs (LANSS) scale, a valid 7-item tool for identifying patients whose pain is dominated by neuropathic mechanisms. Each item is a binary response (yes or no) to the presence of symptoms (5 items) or clinical signs (2 items), range 0-24 points. A score ≥ 12, neuropathic mechanisms are likely to be contributing to the patient's pain. A score < 12 is unlikely to be contributing. McGill questionnaire (Sensory domain) - 11 descriptors rated on an intensity scale as 0=none, 1=mild, 2=moderate, 3=severe. The higher the score, greater the pain (range 0-33). McGill questionnaire (Motivational-affective) 4 affect descriptors rated on an intensity scale as 0=none, 1=mild, 2=moderate, 3=severe.The higher the score the greater the pain (range 0-12) Brief pain inventory - pain severity (0, no pain, 10 excruciating pain); Greater the score; greater the pain (range 0-10). (NCT01619852)
Timeframe: 3 months

,
Interventionunits on a scale (Median)
S-LANNSMcGill Questionaire-Sensory DiscrimationMcGill Questionaire-Motivational-affectiveBrief Pain Inventory
.9% Normal Saline Placebo3301
Group L3401

Evaluate Incidence of Respiratory Depression as Evidenced by Pulse Oximetry Data

(NCT00886236)
Timeframe: 48 hours

Intervention% oxygen saturation (Mean)
1 Preoperative Gabapentin Liquid93
2 Preoperative and Postoperative Gabapentin Liquid94
3 Preoperative and Postoperative Placebo Liquid95

Evaluate the Amount of Diluadid Given Postoperatively

The amount of intraoperative and postoperative opioids used will be collected and analyzed for the three different arms. (NCT00886236)
Timeframe: 120 hours

Interventionml (Mean)
1 Preoperative Gabapentin Liquid11.035
2 Preoperative and Postoperative Gabapentin Liquid8.7
3 Preoperative and Postoperative Placebo Liquid12.4

Number of Participants Who Experience Incidence of Postoperative Nausea.

(NCT00886236)
Timeframe: 120 hours

InterventionParticipants (Count of Participants)
1 Preoperative Gabapentin Liquid12
2 Preoperative and Postoperative Gabapentin Liquid11
3 Preoperative and Postoperative Placebo Liquid12

Reviews

12 reviews available for gabapentin and Acute Disease

ArticleYear
Interventions for treating acute high altitude illness.
    The Cochrane database of systematic reviews, 2018, 06-30, Volume: 6

    Topics: Acetazolamide; Acute Disease; Adolescent; Adult; Altitude Sickness; Amines; Anticonvulsants; Atmosph

2018
Single dose oral gabapentin for established acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2010, May-12, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapen

2010
Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epileps
    Neurology, 2004, Apr-27, Volume: 62, Issue:8

    Topics: Acetates; Acute Disease; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Controlle

2004
Lamotrigine and antiepileptic drugs as mood stabilizers in bipolar disorder.
    Acta psychiatrica Scandinavica. Supplementum, 2005, Issue:426

    Topics: Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexa

2005
Anticonvulsant drugs for acute and chronic pain.
    The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3

    Topics: Acute Disease; Amines; Anticonvulsants; Chronic Disease; Controlled Clinical Trials as Topic; Cycloh

2005
Gabapentin for acute and chronic pain.
    The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3

    Topics: Acute Disease; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Ga

2005
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2006
GABAergic drugs for the treatment of migraine.
    CNS & neurological disorders drug targets, 2007, Volume: 6, Issue:4

    Topics: Acute Disease; Amines; Animals; Cyclohexanecarboxylic Acids; Fructose; GABA Agents; GABA Antagonists

2007
Pain management in the traumatic amputee.
    Critical care nursing clinics of North America, 2008, Volume: 20, Issue:1

    Topics: Acute Disease; Afghanistan; Amines; Amputation, Traumatic; Analgesia; Analgesics; Benchmarking; Caus

2008
Acute pain: combination treatments and how we measure their efficacy.
    British journal of anaesthesia, 2008, Volume: 101, Issue:1

    Topics: Acute Disease; Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Drug Administration Sc

2008
Aggravation of focal epileptic seizures by antiepileptic drugs.
    Epilepsia, 1998, Volume: 39 Suppl 3

    Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarbox

1998
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
    Bipolar disorders, 2001, Volume: 3, Issue:5

    Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine;

2001

Trials

15 trials available for gabapentin and Acute Disease

ArticleYear
Addressing challenges of clinical trials in acute pain: The Pain Management of Vaso-occlusive Crisis in Children and Young Adults with Sickle Cell Disease Study.
    Clinical trials (London, England), 2016, Volume: 13, Issue:4

    Topics: Acute Disease; Acute Pain; Adolescent; Adult; Amines; Analgesics; Anemia, Sickle Cell; Child; Child,

2016
A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster.
    Pain, 2009, Volume: 142, Issue:3

    Topics: Acute Disease; Aged; Amines; Analgesics, Opioid; Clinical Trials as Topic; Cyclohexanecarboxylic Aci

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Repla

2009
Acupuncture in acute herpes zoster pain therapy (ACUZoster) - design and protocol of a randomised controlled trial.
    BMC complementary and alternative medicine, 2009, Aug-12, Volume: 9

    Topics: Acupuncture Therapy; Acute Disease; Adult; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxyli

2009
Acupuncture in acute herpes zoster pain therapy (ACUZoster) - design and protocol of a randomised controlled trial.
    BMC complementary and alternative medicine, 2009, Aug-12, Volume: 9

    Topics: Acupuncture Therapy; Acute Disease; Adult; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxyli

2009
Acupuncture in acute herpes zoster pain therapy (ACUZoster) - design and protocol of a randomised controlled trial.
    BMC complementary and alternative medicine, 2009, Aug-12, Volume: 9

    Topics: Acupuncture Therapy; Acute Disease; Adult; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxyli

2009
Acupuncture in acute herpes zoster pain therapy (ACUZoster) - design and protocol of a randomised controlled trial.
    BMC complementary and alternative medicine, 2009, Aug-12, Volume: 9

    Topics: Acupuncture Therapy; Acute Disease; Adult; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxyli

2009
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analg

2009
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analg

2009
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analg

2009
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analg

2009
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ch

2010
Evaluation of efficacy of the perioperative administration of Venlafaxine or gabapentin on acute and chronic postmastectomy pain.
    The Clinical journal of pain, 2010, Volume: 26, Issue:5

    Topics: Acute Disease; Adult; Amines; Analgesics; Breast Neoplasms; Chronic Disease; Cyclohexanecarboxylic A

2010
The effects of gabapentin on acute and chronic postoperative pain after coronary artery bypass graft surgery.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:5

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Chronic Disease; Chronic Pain; Coronary

2011
Adjunctive treatment with gabapentin in bipolar patients during acute mania.
    International journal of psychiatry in medicine, 2012, Volume: 43, Issue:3

    Topics: Acute Disease; Age Distribution; Amines; Analysis of Variance; Antimanic Agents; Bipolar Disorder; C

2012
Analgesic effects of gabapentin after spinal surgery.
    Anesthesiology, 2004, Volume: 100, Issue:4

    Topics: Acetates; Acute Disease; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method

2004
A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster.
    Neurology, 2005, Aug-09, Volume: 65, Issue:3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anticonvulsants; Cross-Over Studi

2005
Multimodal analgesia with gabapentin and local anesthetics prevents acute and chronic pain after breast surgery for cancer.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:5

    Topics: Acute Disease; Adult; Amines; Analgesia; Anesthetics, Local; Breast Neoplasms; Chronic Disease; Cycl

2005
Clinical experience with gabapentin in patients with bipolar or schizoaffective disorder: results of an open-label study.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:4

    Topics: Acetates; Acute Disease; Adult; Aged; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agent

1999
Gabapentin in the acute treatment of refractory bipolar disorder.
    Bipolar disorders, 1999, Volume: 1, Issue:1

    Topics: Acetates; Acute Disease; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Ac

1999
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
    Bipolar disorders, 2001, Volume: 3, Issue:5

    Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine;

2001

Other Studies

31 other studies available for gabapentin and Acute Disease

ArticleYear
Retrospective analysis of a gabapentin high dose taper compared to lorazepam in acute inpatient alcohol withdrawal.
    The American journal of drug and alcohol abuse, 2019, Volume: 45, Issue:4

    Topics: Acute Disease; Adult; Alcoholism; Electronic Health Records; Endpoint Determination; Female; GABA Ag

2019
Gabapentin alleviates chronic spontaneous pain and acute hypoxia-related pain in a mouse model of sickle cell disease.
    British journal of haematology, 2019, Volume: 187, Issue:2

    Topics: Acute Disease; Anemia, Sickle Cell; Animals; Calcium Channels, L-Type; Chronic Pain; Disease Models,

2019
Association of Gabapentin or Pregabalin Use and Incidence of Acute Angle-closure Glaucoma.
    Journal of glaucoma, 2019, Volume: 28, Issue:9

    Topics: Acute Disease; Adult; Analgesics; Case-Control Studies; Female; Gabapentin; Glaucoma, Angle-Closure;

2019
Acute dystonic reaction caused by gabapentin.
    The Journal of emergency medicine, 2014, Volume: 46, Issue:3

    Topics: Acute Disease; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Dystonia; Gabapentin

2014
Pharmacological characterization of standard analgesics on oxaliplatin-induced acute cold hypersensitivity in mice.
    Journal of pharmacological sciences, 2014, Volume: 124, Issue:4

    Topics: Acute Disease; Amines; Analgesics; Animals; Antineoplastic Agents; Calcium Gluconate; Cryopyrin-Asso

2014
Gabapentin, a synthetic analogue of gamma aminobutyric acid, reverses systemic acute inflammation and oxidative stress in mice.
    Inflammation, 2014, Volume: 37, Issue:5

    Topics: Acute Disease; Amines; Animals; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Edema; Gabape

2014
In vivo two-photon imaging of structural dynamics in the spinal dorsal horn in an inflammatory pain model.
    The European journal of neuroscience, 2015, Volume: 41, Issue:7

    Topics: Acute Disease; Amines; Animals; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Ac

2015
Incidence of postherpetic neuralgia after combination treatment with gabapentin and valacyclovir in patients with acute herpes zoster: open-label study.
    Archives of dermatology, 2011, Volume: 147, Issue:8

    Topics: Acute Disease; Acyclovir; Aged; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; D

2011
Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: Acetates; Acute Disease; Adrenergic alpha-Agonists; Amines; Analgesics, Non-Narcotic; Analgesics, Op

2002
[Gabapentine-induced acute hepatitis].
    Gastroenterologie clinique et biologique, 2003, Volume: 27, Issue:12

    Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cyclohexan

2003
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:4

    Topics: Acute Disease; Amines; Analgesics, Opioid; Animals; Carbamates; Cyclohexanecarboxylic Acids; Disease

2004
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cycl

2004
Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Acetates; Acute Disease; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bradykin

2004
Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:3

    Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Benzylamines; Chronic Disease; Cyclohexanecarb

2005
Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:3

    Topics: Acute Disease; Amines; Animals; Brain Ischemia; Cyclohexanecarboxylic Acids; Dose-Response Relations

2006
Does acute pain associated with herpes zoster respond to treatment with gabapentin?
    Nature clinical practice. Neurology, 2006, Volume: 2, Issue:6

    Topics: Acute Disease; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Met

2006
Transverse myelitis caused by varicella zoster: case reports.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2007, Volume: 11, Issue:1

    Topics: Acute Disease; Amines; Amitriptyline; Analgesics, Non-Narcotic; Chickenpox; Cyclohexanecarboxylic Ac

2007
Life-threatening status epilepticus following gabapentin administration in a patient with benign adult familial myoclonic epilepsy.
    Epilepsia, 2007, Volume: 48, Issue:10

    Topics: Acute Disease; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Drug Resistanc

2007
Case reports: zoster pain in haematological malignancies: effective pain relief with oxycodone in patients unresponsive to other analgesic measures.
    Herpes : the journal of the IHMF, 2007, Volume: 14, Issue:2

    Topics: Acute Disease; Aged; Aged, 80 and over; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic

2007
Role of Stellate ganglion block in post CABG sympathetically mediated chest pain.
    JPMA. The Journal of the Pakistan Medical Association, 2007, Volume: 57, Issue:9

    Topics: Acute Disease; Amines; Antidepressive Agents, Tricyclic; Chest Pain; Coronary Artery Bypass; Cyclohe

2007
Nociceptin-receptor deficiency prevents postherpetic pain without effects on acute herpetic pain in mice.
    Neuroreport, 2008, Jan-08, Volume: 19, Issue:1

    Topics: Acute Disease; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gab

2008
Treatment of acute mania with gabapentin.
    The American journal of psychiatry, 1997, Volume: 154, Issue:2

    Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Aci

1997
The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain.
    European journal of pharmacology, 1997, Apr-18, Volume: 324, Issue:2-3

    Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Anticonvulsants; Chronic Disease; Cyclohexanec

1997
Acute treatment of bipolar depression with gabapentin.
    Biological psychiatry, 1997, Nov-01, Volume: 42, Issue:9

    Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Aci

1997
Gabapentin as monotherapy in the treatment of acute mania.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:3

    Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Aci

1999
Open maintenance treatment of bipolar disorder spectrum patients who responded to gabapentin augmentation in the acute phase of treatment.
    Journal of affective disorders, 1999, Volume: 55, Issue:2-3

    Topics: Acetates; Acute Disease; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Ac

1999
Gabapentin in acute painful diabetic neuropathy.
    European journal of neurology, 2000, Volume: 7, Issue:3

    Topics: Acetates; Acute Disease; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathie

2000
Reversible acute renal allograft dysfunction due to gabapentin.
    Transplantation, 2000, Jul-15, Volume: 70, Issue:1

    Topics: Acetates; Acute Disease; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin;

2000
Herpes zoster.
    The New England journal of medicine, 2000, Jul-20, Volume: 343, Issue:3

    Topics: Acetates; Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobut

2000
Effects of analgesics on delayed postherpetic pain in mice.
    Anesthesiology, 2002, Volume: 96, Issue:5

    Topics: Acetates; Acute Disease; Acyclovir; Amines; Analgesics; Analgesics, Opioid; Animals; Antiviral Agent

2002
Gabapentin for neuropathic pain following spinal cord injury.
    Spinal cord, 2002, Volume: 40, Issue:6

    Topics: Acetates; Acute Disease; Adolescent; Adult; Aged; Amines; Chronic Disease; Cyclohexanecarboxylic Aci

2002