Page last updated: 2024-10-27

gabapentin and Acute Confusional Senile Dementia

gabapentin has been researched along with Acute Confusional Senile Dementia in 19 studies

Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.

Research Excerpts

ExcerptRelevanceReference
"Following PRISMA guidelines, we systematically reviewed evidence for gabapentin and pregabalin against BPSD symptoms of agitation or aggression in any dementia, using six databases (Pubmed, CINHL, PsychINFO, HealthStar, Embase, and Web of Science)."5.01Gabapentin and pregabalin to treat aggressivity in dementia: a systematic review and illustrative case report. ( Abdool, PS; Asmer, S; Bolea-Alamanac, BM; Davies, SJC; Supasitthumrong, T; Woo, VL, 2019)
" In the New Drug Application for gabapentin, data from two adequate and well-controlled clinical trials was submitted to the Food and Drug Administration (FDA) in support of the approval of the indication for the treatment of post-herpetic neuralgia."4.82How modeling and simulation have enhanced decision making in new drug development. ( Corrigan, BW; Donevan, S; El-Kattan, A; Ewy, W; Feltner, DE; Hermann, D; Koup, JR; Kowalski, KG; Lalonde, RL; Li, CS; Lockwood, P; Miller, R; Ouellet, D; Werth, JL, 2005)
" Examining antiepileptic prescribing to residents with ADRD who had disruptive behaviors and/or reported pain suggests that two of the most common antiepileptics, valproic acid and gabapentin, are being used in clinically distinct ways."4.31Antiepileptic prescribing to persons living with dementia residing in nursing homes: A tale of two indications. ( Candon, M; Gerlach, LB; Maust, DT; Strominger, J, 2023)
"Gabapentin has been administered to several geriatric patients with bipolar disorder and patients with dementia."2.44Use of gabapentin in the treatment of behavioural and psychological symptoms of dementia: a review of the evidence. ( Kim, Y; Tampi, RR; Wilkins, KM, 2008)
" Through molecular screening targeting the C terminal region of Aβ, a region involved in the toxic properties of the peptide, we detected an FDA approved compound, gabapentin (GBP), with neuroprotective effects against Aβ toxicity."1.56Gabapentin Inhibits Multiple Steps in the Amyloid Beta Toxicity Cascade. ( Aguayo, LG; Bascuñán, D; Bobadilla-Azócar, C; Boopathi, S; Burgos, CF; Fernández-Pérez, A; Fernández-Pérez, EJ; Figueroa, M; González, W; González-Sanmiguel, J; Riffo-Lepe, N; Vicente, B, 2020)
" Chronic administration of the synthetic gonadotropin (luteinising hormone) releasing hormone analogue, goserelin, reduces testosterone activity."1.33Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report. ( Raskind, MA; Rosin, RA, 2005)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's10 (52.63)29.6817
2010's3 (15.79)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Boopathi, S2
Poma, AB1
Garduño-Juárez, R1
Oh, GY1
Moga, DC1
Abner, EL1
Candon, M1
Strominger, J1
Gerlach, LB1
Maust, DT1
González-Sanmiguel, J1
Burgos, CF1
Bascuñán, D1
Fernández-Pérez, EJ1
Riffo-Lepe, N1
Fernández-Pérez, A1
Bobadilla-Azócar, C1
González, W1
Figueroa, M1
Vicente, B1
Aguayo, LG1
Aman, Y1
Pitcher, T1
Ballard, C1
Malcangio, M1
Supasitthumrong, T1
Bolea-Alamanac, BM1
Asmer, S1
Woo, VL1
Abdool, PS1
Davies, SJC1
Cooney, C1
Murphy, S1
Tessema, H1
Freyne, A1
Biselx, S1
Büla, C1
Ghika, J1
Alkhalil, C1
Hahar, N1
Alkhalil, B1
Zavros, G1
Lowenthal, DT1
Raudino, F1
Mascalzi, MG1
Zagami, A1
Rosin, RA1
Raskind, MA1
Miller, R2
Ewy, W2
Corrigan, BW2
Ouellet, D1
Hermann, D1
Kowalski, KG2
Lockwood, P1
Koup, JR1
Donevan, S1
El-Kattan, A1
Li, CS1
Werth, JL1
Feltner, DE1
Lalonde, RL2
Hutmacher, MM1
Nichols, DJ1
Milligan, PA1
Lockwood, PA1
Marshall, SA1
Benincosa, LJ1
Tensfeldt, TG1
Parivar, K1
Amantea, M1
Glue, P1
Koide, H1
Kim, Y1
Wilkins, KM1
Tampi, RR1
Regan, WM1
Gordon, SM1
Sheldon, LJ1
Ancill, RJ1
Holliday, SG1
Roane, DM1
Feinberg, TE1
Meckler, L1
Miner, CR1
Scicutella, A1
Rosenthal, RN1
Dallocchio, C1
Buffa, C1
Mazzarello, P1
Moretti, R1
Torre, P1
Antonello, RM1
Cazzato, G1

Reviews

5 reviews available for gabapentin and Acute Confusional Senile Dementia

ArticleYear
An Overview of Several Inhibitors for Alzheimer's Disease: Characterization and Failure.
    International journal of molecular sciences, 2021, Oct-06, Volume: 22, Issue:19

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Anxiety Agents; Gabapentin; Humans; Hydroxyq

2021
Gabapentin and pregabalin to treat aggressivity in dementia: a systematic review and illustrative case report.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:4

    Topics: Aged; Aggression; Alzheimer Disease; Calcium Channel Blockers; Dose-Response Relationship, Drug; Gab

2019
How modeling and simulation have enhanced decision making in new drug development.
    Journal of pharmacokinetics and pharmacodynamics, 2005, Volume: 32, Issue:2

    Topics: Alzheimer Disease; Amines; Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III a

2005
Model-based drug development.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:1

    Topics: Alzheimer Disease; Amines; Analgesics; Animals; Anticholesteremic Agents; Bridged Bicyclo Compounds,

2007
Use of gabapentin in the treatment of behavioural and psychological symptoms of dementia: a review of the evidence.
    Drugs & aging, 2008, Volume: 25, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amines; Behavior; Cyclohexanecarboxylic Acids; Dementia,

2008

Trials

1 trial available for gabapentin and Acute Confusional Senile Dementia

ArticleYear
Gabapentin as a possible treatment of behavioral alterations in Alzheimer disease (AD) patients.
    European journal of neurology, 2001, Volume: 8, Issue:5

    Topics: Acetates; Aged; Alzheimer Disease; Amines; Behavior; Cyclohexanecarboxylic Acids; Excitatory Amino A

2001

Other Studies

13 other studies available for gabapentin and Acute Confusional Senile Dementia

ArticleYear
Gabapentin utilization among older adults with different cognitive statuses enrolled in the National Alzheimer's Coordinating Center (2006-2019).
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:1

    Topics: Aged; Alzheimer Disease; Analgesics, Opioid; Antidepressive Agents; Antipsychotic Agents; Benzodiaze

2023
Antiepileptic prescribing to persons living with dementia residing in nursing homes: A tale of two indications.
    Journal of the American Geriatrics Society, 2023, Volume: 71, Issue:1

    Topics: Aged; Alzheimer Disease; Analgesics, Opioid; Anticonvulsants; Antipsychotic Agents; Gabapentin; Huma

2023
Gabapentin Inhibits Multiple Steps in the Amyloid Beta Toxicity Cascade.
    ACS chemical neuroscience, 2020, 10-07, Volume: 11, Issue:19

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Gabapentin; Hippocampus; Humans; Neurons; Peptide

2020
Impaired chronic pain-like behaviour and altered opioidergic system in the TASTPM mouse model of Alzheimer's disease.
    European journal of pain (London, England), 2019, Volume: 23, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analgesics; Analgesics, Opioid; Animals; Arthralg

2019
Use of low-dose gabapentin for aggressive behavior in vascular and Mixed Vascular/Alzheimer Dementia.
    The Journal of neuropsychiatry and clinical neurosciences, 2013,Spring, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Dementi

2013
[Restless legs syndrome in the elderly: an unrecognized disorder].
    Revue medicale suisse, 2008, Nov-05, Volume: 4, Issue:178

    Topics: Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxyli

2008
Can gabapentin be a safe alternative to hormonal therapy in the treatment of inappropriate sexual behavior in demented patients?
    International urology and nephrology, 2003, Volume: 35, Issue:2

    Topics: Acetates; Aged; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyr

2003
Gabapentin and behavioral disorders in severe Alzheimer disease.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:4

    Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Female; F

2004
Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report.
    International psychogeriatrics, 2005, Volume: 17, Issue:2

    Topics: Aged; Aggression; Alzheimer Disease; Amines; Antipsychotic Agents; Benzodiazepines; Cyclohexanecarbo

2005
Gabapentin for behavioral agitation in Alzheimer's disease.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:1

    Topics: Acetates; Aged; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Admini

1997
Gabapentin in geriatric psychiatry patients.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:4

    Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Bipolar Disorder; Cyc

1998
Treatment of dementia-associated agitation with gabapentin.
    The Journal of neuropsychiatry and clinical neurosciences, 2000,Winter, Volume: 12, Issue:1

    Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic

2000
Combination of donepezil and gabapentin for behavioral disorders in Alzheimer's disease.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:1

    Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cholinesterase Inhibi

2000