gabapentin has been researched along with Acute Brain Injuries in 13 studies
Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.
gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gabapentin treatment significantly improved the behavioral scores, decreased levels of phosphorylated IκB-α and cleaved caspase3, apoptosis rate, and serum IL-6 level in ICH rats." | 5.72 | Gabapentin Alleviates Brain Injury in Intracerebral Hemorrhage Through Suppressing Neuroinflammation and Apoptosis. ( Guo, L; Li, X; Nan, C; Sun, Z; Wang, B; Yang, L; Yu, N; Zhao, Z, 2022) |
| "Acquired brain injury can cause eye movement disorders which may include: strabismus, gaze deficits and nystagmus, causing visual symptoms of double, blurred or 'juddery' vision and reading difficulties." | 2.58 | Interventions for eye movement disorders due to acquired brain injury. ( Dodridge, CS; Evans, JR; Garcia-Finana, M; Hanna, K; Howard, C; Jarvis, KA; Maan, T; MacDiarmid, SL; Noonan, CP; North, L; Rodgers, H; Rowe, FJ, 2018) |
| "Gabapentin treatment significantly improved the behavioral scores, decreased levels of phosphorylated IκB-α and cleaved caspase3, apoptosis rate, and serum IL-6 level in ICH rats." | 1.72 | Gabapentin Alleviates Brain Injury in Intracerebral Hemorrhage Through Suppressing Neuroinflammation and Apoptosis. ( Guo, L; Li, X; Nan, C; Sun, Z; Wang, B; Yang, L; Yu, N; Zhao, Z, 2022) |
| "Macroglossia has been reported in patients undergoing posterior fossa neurosurgical procedures and is thought to be as a result of venous engorgement from intubation or mechanical positioning during these prolonged procedures." | 1.40 | Macroglossia associated with brainstem injury. ( Ardelt, A; Cueva, W; Frank, J; Goldenberg, F; Iwuchukwu, I; Reshi, R, 2014) |
| "Early treatment of epilepsy is warranted to avoid possible severe consequences." | 1.39 | Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle. ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013) |
| "Intracranial stab wounds are low-velocity, penetrating injuries to the brain and fatality and outcome significantly depend on route, depth and location of cranial penetration." | 1.39 | Self-inflicted trans-oral intracranial stab wound. ( Han, ZA; Kim, JH; Kim, SW, 2013) |
| "Gabapentin (GBP) is an anticonvulsant that acts at the α2δ-1 submit of the L-type calcium channel." | 1.38 | Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma. ( Barres, BA; Graber, KD; Jin, S; Li, H; McDonald, W; Prince, DA, 2012) |
| "Paroxysmal autonomic instability with dystonia, an under-recognized and poorly understood phenomenon of episodic central dysautonomia is associated with various cerebral insults." | 1.34 | Paroxysmal autonomic instability with dystonia. ( Lim, CC; Srinivasan, S; Thirugnanam, U, 2007) |
| "The severe burning pain, deep pressure-like pain, and deep mechanical allodynia, which presented over the contralateral side to the TBI, were successfully relieved with motor cortex stimulation (MCS)." | 1.33 | Motor cortex stimulation for central pain following a traumatic brain injury. ( Choi, ES; Hong, JT; Lee, SW; Son, BC; Sung, JH, 2006) |
| "Nonconvulsive seizures (NCSs) after traumatic and ischemic brain injury are often refractory to antiepileptic drug therapy and are associated with a decline in patient outcome." | 1.32 | Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. ( Hartings, JA; Lu, XM; Moreton, JE; Tortella, FC; Williams, AJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 1 |
| Wang, B | 1 |
| Yu, N | 1 |
| Yang, L | 1 |
| Nan, C | 1 |
| Sun, Z | 1 |
| Guo, L | 1 |
| Zhao, Z | 1 |
| Rowe, FJ | 1 |
| Hanna, K | 1 |
| Evans, JR | 1 |
| Noonan, CP | 1 |
| Garcia-Finana, M | 1 |
| Dodridge, CS | 1 |
| Howard, C | 1 |
| Jarvis, KA | 1 |
| MacDiarmid, SL | 1 |
| Maan, T | 1 |
| North, L | 1 |
| Rodgers, H | 1 |
| Yamada, H | 1 |
| Kikuchi, R | 1 |
| Katayama, J | 1 |
| Nakamura, A | 1 |
| Miyazaki, H | 1 |
| Belozertsev, IuA | 1 |
| Zapol'skaia, IuA | 1 |
| Belozertsev, FIu | 1 |
| Iuntsev, SV | 1 |
| Rapinesi, C | 1 |
| Del Casale, A | 1 |
| Serata, D | 1 |
| Kotzalidis, GD | 1 |
| Scatena, P | 1 |
| Muzi, A | 1 |
| Lazanio, S | 1 |
| Savoja, V | 1 |
| Carbonetti, P | 1 |
| Fensore, C | 1 |
| Ferracuti, S | 1 |
| Angeletti, G | 1 |
| Tatarelli, R | 1 |
| Girardi, P | 1 |
| Kim, SW | 1 |
| Kim, JH | 1 |
| Han, ZA | 1 |
| Iwuchukwu, I | 1 |
| Ardelt, A | 1 |
| Cueva, W | 1 |
| Reshi, R | 1 |
| Goldenberg, F | 1 |
| Frank, J | 1 |
| Li, H | 1 |
| Graber, KD | 1 |
| Jin, S | 1 |
| McDonald, W | 1 |
| Barres, BA | 1 |
| Prince, DA | 1 |
| Williams, AJ | 1 |
| Tortella, FC | 1 |
| Lu, XM | 1 |
| Moreton, JE | 1 |
| Hartings, JA | 1 |
| Son, BC | 1 |
| Lee, SW | 1 |
| Choi, ES | 1 |
| Sung, JH | 1 |
| Hong, JT | 1 |
| Baguley, IJ | 1 |
| Heriseanu, RE | 1 |
| Gurka, JA | 1 |
| Nordenbo, A | 1 |
| Cameron, ID | 1 |
| Srinivasan, S | 1 |
| Lim, CC | 1 |
| Thirugnanam, U | 1 |
| Childers, MK | 1 |
| Holland, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment and Its Impact on Occupational Performance[NCT06067607] | 10 participants (Anticipated) | Interventional | 2023-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for gabapentin and Acute Brain Injuries
| Article | Year |
|---|---|
Interventions for eye movement disorders due to acquired brain injury.
Topics: 4-Aminopyridine; Abducens Nerve Diseases; Amifampridine; Amines; Baclofen; Botulinum Toxins; Brain I | 2018 |
12 other studies available for gabapentin and Acute Brain Injuries
| Article | Year |
|---|---|
Gabapentin Alleviates Brain Injury in Intracerebral Hemorrhage Through Suppressing Neuroinflammation and Apoptosis.
Topics: Animals; Apoptosis; Brain; Brain Injuries; Cerebral Hemorrhage; Gabapentin; Hemin; Inflammation; Int | 2022 |
Paroxysmal Sympathetic Hyperactivity after Surgery for Cerebral Hemorrhagic Arteriovenous Malformation: A Case Report.
Topics: Adolescent; Adrenergic beta-Antagonists; Amines; Autonomic Nervous System Diseases; Brain Injuries; | 2018 |
[Comparison of neuroprotective effects of anticonvulsant drugs in brain injury therapy].
Topics: Amines; Animals; Animals, Outbred Strains; Anticonvulsants; Brain; Brain Injuries; Brain Ischemia; C | 2012 |
Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle.
Topics: Accidents, Traffic; Aggression; Amines; Anterior Temporal Lobectomy; Anticonvulsants; Brain Injuries | 2013 |
Self-inflicted trans-oral intracranial stab wound.
Topics: Amines; Analgesics; Antidepressive Agents; Brain Injuries; Cerebellum; Citalopram; Cyclohexanecarbox | 2013 |
Macroglossia associated with brainstem injury.
Topics: Adolescent; Adrenergic beta-Antagonists; Aged; Amines; Anti-Inflammatory Agents; Brain Injuries; Bra | 2014 |
Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma.
Topics: Amines; Animals; Anticonvulsants; Blotting, Western; Brain Injuries; Cyclohexanecarboxylic Acids; Di | 2012 |
Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia.
Topics: Amines; Animals; Anticonvulsants; Brain Infarction; Brain Injuries; Brain Ischemia; Cyclohexanecarbo | 2004 |
Motor cortex stimulation for central pain following a traumatic brain injury.
Topics: Accidental Falls; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Aphasia, Broca; Brain Inju | 2006 |
Gabapentin in the management of dysautonomia following severe traumatic brain injury: a case series.
Topics: Adolescent; Adult; Amines; Anticonvulsants; Autonomic Nervous System Diseases; Brain Injuries; Cyclo | 2007 |
Paroxysmal autonomic instability with dystonia.
Topics: Adult; Amines; Autonomic Nervous System Diseases; Benzodiazepines; Brain Injuries; Cyclohexanecarbox | 2007 |
Psychomotor agitation following gabapentin use in brain injury.
Topics: Acetates; Adult; Akathisia, Drug-Induced; Amines; Analgesics; Brain Injuries; Cyclohexanecarboxylic | 1997 |