gabapentin and ALS - Amyotrophic Lateral Sclerosis

gabapentin has been researched along with ALS - Amyotrophic Lateral Sclerosis in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (62.50)18.2507
2000's6 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Armon, C1
Arnold, DL; Caramanos, Z; Cashman, NR; Genge, A; Kalra, S1
Jackson, CE; Miller, RG; Moore, DH1
Cory, PR; Gidal, Be1
Rothstein, JD; Schielke, GP; Welty, DF1
Romano, JG1
Armon, C; Barohn, RJ; Bromberg, MB; Bryan, WW; Gelinas, DF; Mendoza, MC; Miller, RG; Moore, D; Neville, HE; Parry, GJ; Petajan, JH; Ravits, JM; Ringel, SP; Ross, MA; Young, LA1
Andrus, PK; Cutting, FB; Doble, A; Gurney, ME; Hall, ED; Taylor, CP; Zhai, P1
Miller, RG2
Balzarini, C; Brigatti, M; Comazzi, F; Mazzini, L; Mora, G; Pastore, E; Pirali, I1
Forshew, DA1
Bernardi, G; Caramia, MD; Desiato, MT; Iani, C; Palmieri, MG; Scalise, A; Telera, S1
McDermott, MP; Rowland, LP1
Amato, AA; Barohn, RJ; Bosch, P; Bromberg, M; Bryan, W; Dronsky, V; Gelinas, DF; Graves, M; Jackson, C; Johnson, W; Kelkar, P; Mandler, R; Mendoza, M; Miller, RG; Moore, DH; Neville, H; Olney, R; Parry, G; Petajan, J; Ravits, J; Ringel, S; Ross, M; Smith, B; Sorenson, EJ; Yuen, E1
Brigell, MG; Taylor, CP1

Reviews

4 review(s) available for gabapentin and ALS - Amyotrophic Lateral Sclerosis

ArticleYear
How can physicians and their patients with ALS decide to use the newly-available treatments to slow disease progression?
    Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 1999, Volume: 1, Issue:1

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Neuroprotective Agents; Quality of Life; Riluzole; Sickness Impact Profile

1999
Potential use of gabapentin and lamotrigine.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:11

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drugs, Investigational; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines

1995
Carrell-Krusen Symposium invited lecture. Clinical trials in motor neuron diseases.
    Journal of child neurology, 1999, Volume: 14, Issue:3

    Topics: Acetates; Adolescent; Adult; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Guidelines as Topic; Humans; Infant; Insulin-Like Growth Factor I; Male; Mice; Middle Aged; Motor Neuron Disease; Muscular Atrophy, Spinal; Nerve Growth Factors; Outcome Assessment, Health Care; Postpoliomyelitis Syndrome; Riluzole

1999
Therapeutic advances: new hope for patients with ALS.
    Nursing spectrum (D.C./Baltimore metro ed.), 1998, Dec-14, Volume: 8, Issue:25

    Topics: Acetates; Aged; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Long-Term Care; Neuroprotective Agents; Patient Education as Topic; Riluzole

1998

Trials

4 trial(s) available for gabapentin and ALS - Amyotrophic Lateral Sclerosis

ArticleYear
Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. WALS Study Group. Western Amyotrophic Lateral Sclerosis Study Group.
    Neurology, 1996, Volume: 47, Issue:6

    Topics: Acetates; Adult; Aged; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged

1996
The natural history and the effects of gabapentin in amyotrophic lateral sclerosis.
    Journal of the neurological sciences, 1998, Volume: 160 Suppl 1

    Topics: Acetates; Administration, Oral; Adult; Aged; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Disability Evaluation; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prognosis; Survival Analysis; Survival Rate

1998
Pharmacologic reversal of cortical hyperexcitability in patients with ALS.
    Neurology, 2000, Jan-11, Volume: 54, Issue:1

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cerebral Cortex; Cyclohexanecarboxylic Acids; Diazepam; Drug Therapy, Combination; Evoked Potentials, Motor; Female; GABA Agonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetics; Male; Middle Aged; Neural Inhibition; Neuroprotective Agents; Physical Stimulation; Riluzole; Synaptic Transmission; Treatment Outcome

2000
Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis.
    Neurology, 2001, Apr-10, Volume: 56, Issue:7

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Sample Size; Survival Analysis

2001

Other Studies

8 other study(ies) available for gabapentin and ALS - Amyotrophic Lateral Sclerosis

ArticleYear
Gabapentin therapy for amyotrophic lateral sclerosis: lack of improvement in neuronal integrity shown by MR spectroscopy.
    AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:3

    Topics: Acetates; Aged; Amines; Amyotrophic Lateral Sclerosis; Aspartic Acid; Cell Survival; Creatine; Cyclohexanecarboxylic Acids; Energy Metabolism; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Parietal Lobe; Reference Values; Treatment Outcome

2003
Western ALS Study Group.
    Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 2004, Volume: 5 Suppl 1

    Topics: Amines; Amyotrophic Lateral Sclerosis; Calcium Channel Blockers; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Cooperative Behavior; Cyclohexanecarboxylic Acids; Cyclophosphamide; Gabapentin; gamma-Aminobutyric Acid; Humans; Minocycline; Societies, Medical; Treatment Outcome

2004
Potential treatment of amyotrophic lateral sclerosis with gabapentin: a hypothesis.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:11

    Topics: Acetates; Amines; Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans

1995
Reduction of fasciculations in patients with amyotrophic lateral sclerosis with the use of gabapentin.
    Archives of neurology, 1996, Volume: 53, Issue:8

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Cyclohexanecarboxylic Acids; Fasciculation; Gabapentin; gamma-Aminobutyric Acid; Humans

1996
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis.
    Annals of neurology, 1996, Volume: 39, Issue:2

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain; Cyclohexanecarboxylic Acids; Diet; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Mice, Transgenic; Oxidative Stress; Riluzole; Spinal Cord; Superoxide Dismutase; Survival Analysis; Thiazoles; Vitamin E

1996
New approaches to therapy of amyotrophic lateral sclerosis.
    The Western journal of medicine, 1998, Volume: 168, Issue:4

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Insulin-Like Growth Factor I; Mice; Riluzole

1998
ALS defeats gabapentin: reflections on another failed treatment.
    Neurology, 2001, Apr-10, Volume: 56, Issue:7

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure

2001
ALS defeats gabapentin: reflections on another failed treatment.
    Neurology, 2001, Oct-23, Volume: 57, Issue:8

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure

2001