g(m3)-ganglioside and Optic-Nerve-Diseases

g(m3)-ganglioside has been researched along with Optic-Nerve-Diseases* in 1 studies

Other Studies

1 other study(ies) available for g(m3)-ganglioside and Optic-Nerve-Diseases

ArticleYear
[Guillain-Barré syndrome with refractory optic neuropathy].
    Rinsho shinkeigaku = Clinical neurology, 2019, Oct-26, Volume: 59, Issue:10

    A 60-year-old woman with a 3-day history of ataxic gait, blurred vision, and upper extremity paresthesia was admitted to our hospital. She presented with severe visual disturbances (finger counting), ophthalmoplegia, neck weakness, and sensory ataxia. Serum anti-GQ1b antibody, anti-GM3 antibody, and anti-GD3 antibody were strongly positive, which might contribute to the pathogenesis. Since we suspected Guillain-Barré syndrome (GBS), intravenous immunoglobulin therapy (IVIg) and high-dose steroid therapy were administered; however, improvements in her visual acuity were minimal. Additional IVIg and high-dose steroid therapy resulted in limited visual acuity improvements. Therapeutic strategies for patients with GBS and refractory optic neuropathy remain controversial.

    Topics: Autoantibodies; Biomarkers; Female; G(M3) Ganglioside; Gangliosides; Guillain-Barre Syndrome; Humans; Immunoglobulins, Intravenous; Methylprednisolone; Middle Aged; Optic Nerve Diseases; Pulse Therapy, Drug

2019