g(m3)-ganglioside has been researched along with Diabetes-Mellitus* in 2 studies
2 review(s) available for g(m3)-ganglioside and Diabetes-Mellitus
| Article | Year |
|---|---|
GM3 and diabetes.
We demonstrated the molecular pathogenesis of type 2 diabetes and insulin resistance focusing on the interaction between insulin receptor and GM3 ganglioside in adipocytes and propose a working hypothesis "metabolic disorders, such as type 2 diabetes, are membrane microdomain disorders caused by aberrant expression of gangliosides". It is expected that the development of novel diagnosis of metabolic syndrome by identifying the specific ganglioside species and a therapeutic strategy "membrane microdomain ortho-signaling therapy". Topics: Amino Acid Sequence; Biomarkers; Diabetes Mellitus; G(M3) Ganglioside; Humans; Insulin Resistance; Metabolic Syndrome; Molecular Sequence Data | 2014 |
Inhibition of ganglioside biosynthesis as a novel therapeutic approach in insulin resistance.
A new concept "Life style-related diseases, such as type 2 diabetes, are a membrane microdomain disorder caused by aberrant expression of gangliosides" has arisen. By examining this working hypothesis, we demonstrate the molecular pathogenesis of type 2 diabetes and insulin resistance focusing on the interaction between insulin receptor and gangliosides in microdomains microdomains and propose the new therapeutic strategy "membrane microdomain ortho-signaling therapy". Topics: Animals; Biomarkers; Caveolae; Diabetes Mellitus; Diabetes Mellitus, Type 2; G(M3) Ganglioside; Gangliosides; Humans; Hypoglycemic Agents; Insulin Resistance; Metabolic Syndrome; Signal Transduction | 2011 |