g(m2)-ganglioside and Breast-Neoplasms

g(m2)-ganglioside has been researched along with Breast-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for g(m2)-ganglioside and Breast-Neoplasms

Article	Year
Preparation and evaluation of unimolecular pentavalent and hexavalent antigenic constructs targeting prostate and breast cancer: a synthetic route to anticancer vaccine candidates. Journal of the American Chemical Society, 2006, Mar-01, Volume: 128, Issue:8 Several novel, fully synthetic, carbohydrate-based antitumor vaccines have been assembled. Each construct consists of multiple cancer-related antigens displayed on a single polypeptide backbone. Recent advances in synthetic methodology have allowed for the incorporation of a complex oligosaccharide terminating in a sialic acid residue (i.e., GM2) as one of the carbohydrate antigens. Details of the vaccine synthesis as well as the results of preliminary immunological investigations are described herein. Topics: Amino Acids; Animals; Antigens, Neoplasm; Breast Neoplasms; Cancer Vaccines; Carbohydrate Sequence; Cell Line, Tumor; Female; G(M2) Ganglioside; Glycosides; Hemocyanins; Humans; Male; Mice; Molecular Sequence Data; Oligosaccharides; Peptides; Prostatic Neoplasms; Sialic Acids	2006

Article

Year

Preparation and evaluation of unimolecular pentavalent and hexavalent antigenic constructs targeting prostate and breast cancer: a synthetic route to anticancer vaccine candidates.

Journal of the American Chemical Society, 2006, Mar-01, Volume: 128, Issue:8

Several novel, fully synthetic, carbohydrate-based antitumor vaccines have been assembled. Each construct consists of multiple cancer-related antigens displayed on a single polypeptide backbone. Recent advances in synthetic methodology have allowed for the incorporation of a complex oligosaccharide terminating in a sialic acid residue (i.e., GM2) as one of the carbohydrate antigens. Details of the vaccine synthesis as well as the results of preliminary immunological investigations are described herein.

Topics: Amino Acids; Animals; Antigens, Neoplasm; Breast Neoplasms; Cancer Vaccines; Carbohydrate Sequence; Cell Line, Tumor; Female; G(M2) Ganglioside; Glycosides; Hemocyanins; Humans; Male; Mice; Molecular Sequence Data; Oligosaccharides; Peptides; Prostatic Neoplasms; Sialic Acids

2006