g(m1)-ganglioside and Myasthenia-Gravis

g(m1)-ganglioside has been researched along with Myasthenia-Gravis* in 1 studies

Other Studies

1 other study(ies) available for g(m1)-ganglioside and Myasthenia-Gravis

ArticleYear
Immune-mediated peripheral neuropathies and voltage-gated sodiums channels.
    Muscle & nerve, 1999, Volume: 22, Issue:1

    Antibodies to GM1 ganglioside are found in some patients with the Guillain-Barré syndrome and multifocal motor neuropathy, and may alter neuronal excitability. We measured voltage-gated sodium channel (VGSC) function by 22Na+ influx in a motor neuronal cell line (NSC19) in which we demonstrated GM1 ganglioside and tetrodotoxin-sensitive VGSC function. We were unable to detect any effect of peripheral neuropathy plasmas, with or without complement, on VGSC function in NSC19 cells.

    Topics: Animals; Autoantibodies; Cell Line; Fluorescent Antibody Technique; G(M1) Ganglioside; Humans; Mice; Miller Fisher Syndrome; Motor Neurons; Myasthenia Gravis; Peripheral Nervous System Diseases; Polyradiculoneuropathy; Sodium; Sodium Channels

1999