fusarin-c has been researched along with Hyperplasia* in 1 studies
1 other study(ies) available for fusarin-c and Hyperplasia
| Article | Year |
|---|---|
[Fusarin C induced esophageal and forestomach carcinoma in mice and rats].
Fusarium moniliforme, a fungus of established carcinogenic potential, is one of the most common fungal contaminants of maize, millet and other grains in Linxian, China, a high-risk county for human esophageal cancer. Fusarin C, a major product of F. moniliforme grown on corn in the laboratory, is mutagenic in Salmonella tester strains and in V79 cells. Fusarin C treated rat esophageal epithelial cell line showed several characteristics of malignant transformations including the growth in nude mice. The present work demonstrated that Fusarin C can induce esophageal and forestomach carcinoma in DBA mice and Wistar rats thus further substantiating the carcinogenicity of this mycotoxin. Topics: Animals; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Hyperplasia; Mice; Mice, Inbred DBA; Papilloma; Polyenes; Precancerous Conditions; Rats; Rats, Inbred Strains; Stomach Neoplasms | 1992 |