fusaric acid has been researched along with Bipolar Disorder in 4 studies
Fusaric Acid: A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pandey, RS | 1 |
| Sreenivas, KN | 1 |
| Patil, NM | 1 |
| Swamy, HS | 1 |
| Luchins, D | 1 |
| Kopin, IJ | 1 |
| Kaufman, S | 1 |
| Viveros, H | 1 |
| Jacobowitz, D | 1 |
| Lake, CR | 1 |
| Ziegler, MG | 1 |
| Lovenberg, W | 1 |
| Goodwin, FK | 2 |
| Sack, RL | 1 |
2 reviews available for fusaric acid and Bipolar Disorder
| Article | Year |
|---|---|
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar | 1976 |
NIH conference. Dopamine- -hydroxylase. Basic and clinical studies.
Topics: Adolescent; Adrenal Medulla; Adult; Animals; Bipolar Disorder; Chemical Phenomena; Chemistry; Child; | 1976 |
2 trials available for fusaric acid and Bipolar Disorder
| Article | Year |
|---|---|
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar | 1976 |
Behavioral effects of a new dopamine-beta-hydroxylase inhibitor (fusaric acid) in man.
Topics: Administration, Oral; Bipolar Disorder; Clinical Trials as Topic; Depression; Dopamine beta-Hydroxyl | 1974 |
1 other study available for fusaric acid and Bipolar Disorder
| Article | Year |
|---|---|
Dopamine beta-hydroxylase inhibition in a patient with Wilson's disease and manic symptoms.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Dopamine beta-Hydroxylase; Fusaric Acid; He | 1981 |