fusafungin and Pleural-Effusion

Gorham-Stout disease is a rare disease characterized by osteolysis, angiomatosis, and soft-tissue swelling. It is a diagnosis of exclusion and has an unknown etiology. Chylothorax is a common complication of the disease that is associated with a high mortality rate. There is no standard of treatment. We report a case of a 16-year-old female with Gorham-Stout disease and recurrent pleural effusions who was successfully treated with concurrent zoledronic acid and peg-interferon α-2b.

Topics: Adolescent; Bone Density Conservation Agents; Depsipeptides; Diphosphonates; Drug Therapy, Combination; Female; Fusarium; Humans; Imidazoles; Interferon alpha-2; Interferon-alpha; Osteolysis, Essential; Pleural Effusion; Polyethylene Glycols; Recombinant Proteins; Zoledronic Acid