Page last updated: 2024-10-27

furosemide and Reperfusion Injury

furosemide has been researched along with Reperfusion Injury in 7 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to determine whether the loop diuretics furosemide, bumetanide and ethacrynic acid, which block the KCC1 potassium-chloride transporter in the kidney loop of Henle and the KCC2 potassium-chloride transporter in neuronal membranes, would prevent sound-triggered seizures in post-ischemic audiogenic seizure-prone rats."3.70Agents which block potassium-chloride cotransport prevent sound-triggered seizures in post-ischemic audiogenic seizure-prone rats. ( Guo, SZ; Iyer, VG; Reid, KH, 2000)
"L-carnitine or furosemide was administered, and serial blood samples were collected and analyzed to assess the effects of hydronephrosis on the pharmacokinetic parameters."1.56Rats with congenital hydronephrosis show increased susceptibility to renal ischemia-reperfusion injury. ( Cirule, H; Dambrova, M; Liepinsh, E; Sevostjanovs, E; Videja, M; Vilks, K; Vilskersts, R; Zharkova-Malkova, O, 2020)
"Treatment with furosemide significantly (p < 0."1.34Furosemide prevents apoptosis and associated gene expression in a rat model of surgical ischemic acute renal failure. ( Aravindan, N; Aravindan, S; Riedel, BJ; Shaw, AD; Weng, HR, 2007)
" Animals were divided into four groups (n = 6 each): (1) sham-operated group infused with saline; (2) sham-operated group infused with 30 microg/kg/hr furosemide (equivalent to a human dosage of 2 mg/hr); (3) unilateral renal ischemia (1 hr, left renal artery cross-clamping) followed by 6 hr of reperfusion; and (4) renal ischemia/ reperfusion (I/R) with furosemide."1.33Effect of furosemide infusion on renal hemodynamics and angiogenesis gene expression in acute renal ischemia/reperfusion. ( Aravindan, N; Shaw, A, 2006)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Vilskersts, R1
Vilks, K1
Videja, M1
Cirule, H1
Zharkova-Malkova, O1
Sevostjanovs, E1
Dambrova, M1
Liepinsh, E1
Zhang, J1
Chen, J2
Chen, Q1
Luo, K1
Pan, L1
Zhang, Y1
Dou, W1
Xing, W1
Bando, Y1
Tsukamoto, Y1
Katayama, T1
Ozawa, K1
Kitao, Y1
Hori, O1
Stern, DM1
Yamauchi, A1
Ogawa, S1
Aravindan, N2
Shaw, A1
Aravindan, S1
Riedel, BJ1
Weng, HR1
Shaw, AD1
Reid, KH1
Guo, SZ1
Iyer, VG1
Schettini, A1
Lippman, RH1
Walsh, EK1

Other Studies

7 other studies available for furosemide and Reperfusion Injury

ArticleYear
Rats with congenital hydronephrosis show increased susceptibility to renal ischemia-reperfusion injury.
    Physiological reports, 2020, Volume: 8, Issue:22

    Topics: Acute Kidney Injury; Animals; Carnitine; Cell Adhesion Molecules; Disease Susceptibility; Diuretics;

2020
Can R
    Magnetic resonance in medicine, 2021, Volume: 86, Issue:2

    Topics: Animals; Furosemide; Hypoxia; Ischemia; Kidney; Rabbits; Reperfusion Injury

2021
ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell death.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:12

    Topics: Animals; Caspase 3; Caspase Inhibitors; Caspases; Cell Death; Cell Line; Cell Survival; Dogs; Epithe

2004
Effect of furosemide infusion on renal hemodynamics and angiogenesis gene expression in acute renal ischemia/reperfusion.
    Renal failure, 2006, Volume: 28, Issue:1

    Topics: Acute Disease; Animals; Diuretics; Furosemide; Gene Expression Regulation; Hemodynamics; Kidney; Mal

2006
Furosemide prevents apoptosis and associated gene expression in a rat model of surgical ischemic acute renal failure.
    Renal failure, 2007, Volume: 29, Issue:4

    Topics: Acute Kidney Injury; Animals; Apoptosis; Disease Models, Animal; Diuretics; DNA Fragmentation; Furos

2007
Agents which block potassium-chloride cotransport prevent sound-triggered seizures in post-ischemic audiogenic seizure-prone rats.
    Brain research, 2000, May-02, Volume: 864, Issue:1

    Topics: Acoustic Stimulation; Animals; Auditory Pathways; Brain; Bumetanide; Carrier Proteins; Diuretics; Ep

2000
Attenuation of decompressive hypoperfusion and cerebral edema by superoxide dismutase.
    Journal of neurosurgery, 1989, Volume: 71, Issue:4

    Topics: Animals; Blood Pressure; Blood-Brain Barrier; Body Water; Brain; Brain Edema; Carbon Dioxide; Cerebr

1989