Page last updated: 2024-10-27

furosemide and Pulmonary Disease, Chronic Obstructive

furosemide has been researched along with Pulmonary Disease, Chronic Obstructive in 21 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.

Research Excerpts

ExcerptRelevanceReference
"Aerosol furosemide may be an option to treat refractory dyspnea, though doses, methods of delivery, and outcomes have been variable."9.34Controlled Delivery of 80 mg Aerosol Furosemide Does Not Achieve Consistent Dyspnea Relief in Patients. ( Banzett, RB; Hallowell, RW; O'Donnell, CR; Schwartzstein, R; Sheridan, A, 2020)
"The aim of this study is to investigate the effects of inhaled furosemide on the sensation of dyspnea produced during exercise in patients with stable chronic obstructive pulmonary disease (COPD)."9.11Effects of inhaled furosemide on exertional dyspnea in chronic obstructive pulmonary disease. ( Chong, WF; Earnest, A; Kor, AC; Ong, KC; Wang, YT, 2004)
"Aerosol furosemide may be an option to treat refractory dyspnea, though doses, methods of delivery, and outcomes have been variable."5.34Controlled Delivery of 80 mg Aerosol Furosemide Does Not Achieve Consistent Dyspnea Relief in Patients. ( Banzett, RB; Hallowell, RW; O'Donnell, CR; Schwartzstein, R; Sheridan, A, 2020)
"The aim of this study is to investigate the effects of inhaled furosemide on the sensation of dyspnea produced during exercise in patients with stable chronic obstructive pulmonary disease (COPD)."5.11Effects of inhaled furosemide on exertional dyspnea in chronic obstructive pulmonary disease. ( Chong, WF; Earnest, A; Kor, AC; Ong, KC; Wang, YT, 2004)
"Furosemide is widely prescribed in patients with COPD for the treatment of peripheral edema."5.10Discontinuation of furosemide decreases PaCO(2) in patients with COPD. ( Brijker, F; Folgering, HT; Heijdra, YF; van den Elshout, FJ, 2002)
"The effective management of dyspnea in COPD remains a significant challenge for caregivers but recent treatment innovations such as helium-oxygen, inhaled furosemide and breathing feedback techniques have yielded early positive results."4.86Exertional dyspnea in chronic obstructive pulmonary disease: mechanisms and treatment approaches. ( Jensen, D; O'Donnell, DE; Ora, J, 2010)
"We will identify all experimental studies using nebulised/inhaled furosemide in patients with asthma or chronic obstructive pulmonary disease that report any outcome."4.31Nebulised furosemide for the treatment of patients with obstructive lung disease: a systematic review protocol. ( Muscedere, J; Veldhoen, R, 2023)
"Forty patients with an AECOPD and high plasma BNP levels, but without any clinical evidence of cor pulmonale, were selected."2.77Intravenous diuretic and vasodilator therapy reduce plasma brain natriuretic peptide levels in acute exacerbation of chronic obstructive pulmonary disease. ( Pan, X; Yu, X; Zhang, J; Zhao, G, 2012)
" Optimal dosing of opioids is being refined."2.44Pharmacological management of dyspnoea. ( Abernethy, AP; Currow, DC, 2007)
"Dyspnea in chronic obstructive pulmonary disease is clearly related to hyperinflation, and lung volumes are valuable for characterizing disease."2.44Mechanisms of dyspnea in chronic lung disease. ( Rock, LK; Schwartzstein, RM, 2007)
" This patient's case highlights the need of further studies evaluating efficacy of repeated dosing of CCP."1.62Sequential dosing of convalescent COVID-19 plasma with significant temporal clinical improvements in a persistently SARS-COV-2 positive patient. ( Bloch, EM; Chua, F; Goel, R; Katz, LM; Mirihagalle, N; Parajuli, P; Prakash, V; Saha, D; Shah, A; Sundareshan, V; Tobian, AAR; Waqar, S, 2021)
"Normocapnic and chronic hypercapnic COPD patients have the same ventilatory and cerebrovascular carbon dioxide responsiveness irrespective of induced metabolic state."1.31Effects of acetazolamide and furosemide on ventilation and cerebral blood volume in normocapnic and hypercapnic patients with COPD. ( Colier, WN; Folgering, H; Oeseburg, B; van de Ven, MJ; van der Sluijs, MC; Vis, P, 2002)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (38.10)29.6817
2010's8 (38.10)24.3611
2020's5 (23.81)2.80

Authors

AuthorsStudies
Veldhoen, R1
Muscedere, J1
Hallowell, RW1
Schwartzstein, R1
O'Donnell, CR1
Sheridan, A1
Banzett, RB1
Syed, MP1
Doshi, A1
Pandey, D1
Kate, Y1
Harizi, R1
Stingo, FE1
Sallam, T1
Govindu, R1
Ammar, H1
Mirihagalle, N1
Parajuli, P1
Sundareshan, V1
Saha, D1
Shah, A1
Chua, F1
Waqar, S1
Prakash, V1
Tobian, AAR1
Bloch, EM1
Katz, LM1
Goel, R1
Lee, G1
Pickstone, N1
Facultad, J1
Titchener, K1
Dotan, Y1
Marchetti, N1
Criner, GJ1
Sheikh Motahar Vahedi, H2
Mahshidfar, B2
Rabiee, H2
Saadat, S2
Shokoohi, H2
Chardoli, M2
Rahimi-Movaghar, V2
Hadda, V1
Madan, K1
Mohan, A1
Ayub, II1
Currow, DC1
Abernethy, AP1
Rock, LK1
Schwartzstein, RM1
Ora, J1
Jensen, D2
O'Donnell, DE2
Prieto de Paula, JM1
Franco Hidalgo, S1
Borge Gallardo, L1
Mayor Toranzo, E1
Zhang, J1
Zhao, G1
Yu, X1
Pan, X1
Ong, KC1
Kor, AC1
Chong, WF1
Earnest, A1
Wang, YT1
Kallet, RH1
Amjadi, K1
Harris-McAllister, V1
Webb, KA1
Cachia, E1
Ahmedzai, SH1
Brijker, F1
Heijdra, YF1
van den Elshout, FJ1
Folgering, HT1
van de Ven, MJ1
Colier, WN1
van der Sluijs, MC1
Oeseburg, B1
Vis, P1
Folgering, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Outgoing Lung Team - a Cross-sectorial and Preventive Intervention in Patients at Risk of Hospitalisation Due to Exacerbation of COPD[NCT04119856]144 participants (Actual)Interventional2017-09-25Completed
Brain During Effort : Effects of Hypoxia With Respiratory Patients[NCT02854280]33 participants (Actual)Interventional2013-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for furosemide and Pulmonary Disease, Chronic Obstructive

ArticleYear
Pharmacological management of dyspnoea.
    Current opinion in supportive and palliative care, 2007, Volume: 1, Issue:2

    Topics: Analgesics, Opioid; Benzodiazepines; Drug Administration Routes; Dyspnea; Forced Expiratory Volume;

2007
Mechanisms of dyspnea in chronic lung disease.
    Current opinion in supportive and palliative care, 2007, Volume: 1, Issue:2

    Topics: Clinical Trials as Topic; Dyspnea; Exercise Tolerance; Furosemide; Humans; Pulmonary Disease, Chroni

2007
Exertional dyspnea in chronic obstructive pulmonary disease: mechanisms and treatment approaches.
    Current opinion in pulmonary medicine, 2010, Volume: 16, Issue:2

    Topics: Analgesics, Opioid; Dyspnea; Feedback, Physiological; Furosemide; Humans; Physical Exertion; Pulmona

2010
The role of inhaled opioids and furosemide for the treatment of dyspnea.
    Respiratory care, 2007, Volume: 52, Issue:7

    Topics: Administration, Inhalation; Analgesics, Opioid; Dyspnea; Female; Furosemide; Humans; Male; Palliativ

2007

Trials

6 trials available for furosemide and Pulmonary Disease, Chronic Obstructive

ArticleYear
Controlled Delivery of 80 mg Aerosol Furosemide Does Not Achieve Consistent Dyspnea Relief in Patients.
    Lung, 2020, Volume: 198, Issue:1

    Topics: Administration, Inhalation; Adult; Aerosols; Aged; Aged, 80 and over; Asthma; Chronic Disease; Cross

2020
The adjunctive effect of nebulized furosemide in COPD exacerbation: a randomized controlled clinical trial.
    Respiratory care, 2013, Volume: 58, Issue:11

    Topics: Administration, Inhalation; Aged; Blood Pressure; Bronchoconstriction; Diuretics; Dose-Response Rela

2013
Intravenous diuretic and vasodilator therapy reduce plasma brain natriuretic peptide levels in acute exacerbation of chronic obstructive pulmonary disease.
    Respirology (Carlton, Vic.), 2012, Volume: 17, Issue:4

    Topics: Aged; Aminophylline; Bronchodilator Agents; Disease Progression; Drug Combinations; Female; Furosemi

2012
Effects of inhaled furosemide on exertional dyspnea in chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2004, May-01, Volume: 169, Issue:9

    Topics: Administration, Inhalation; Aged; Anthropometry; Attitude to Health; Cross-Over Studies; Diuretics;

2004
Mechanisms of dyspnoea relief and improved exercise endurance after furosemide inhalation in COPD.
    Thorax, 2008, Volume: 63, Issue:7

    Topics: Administration, Inhalation; Adult; Aged; Cross-Over Studies; Double-Blind Method; Dyspnea; Exercise

2008
Discontinuation of furosemide decreases PaCO(2) in patients with COPD.
    Chest, 2002, Volume: 121, Issue:2

    Topics: Aged; Aged, 80 and over; Body Fluids; Carbon Monoxide; Cross-Over Studies; Diuretics; Double-Blind M

2002

Other Studies

11 other studies available for furosemide and Pulmonary Disease, Chronic Obstructive

ArticleYear
Nebulised furosemide for the treatment of patients with obstructive lung disease: a systematic review protocol.
    BMJ open, 2023, Nov-23, Volume: 13, Issue:11

    Topics: Asthma; Bronchodilator Agents; Furosemide; Humans; Pulmonary Disease, Chronic Obstructive; Systemati

2023
A rare case of biventricular non-compaction.
    BMJ case reports, 2020, May-13, Volume: 13, Issue:5

    Topics: Cardiomyopathies; Carvedilol; Coronary Artery Disease; Dyspnea; Furosemide; Heart Failure; Heart Ven

2020
It Is Not Pneumonia! A Case of Unilateral Pulmonary Edema.
    The American journal of medicine, 2021, Volume: 134, Issue:1

    Topics: Aged; Diagnosis, Differential; Female; Furosemide; Humans; Natriuretic Peptide, Brain; Peptide Fragm

2021
Sequential dosing of convalescent COVID-19 plasma with significant temporal clinical improvements in a persistently SARS-COV-2 positive patient.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2021, Volume: 60, Issue:5

    Topics: Anti-Bacterial Agents; Combined Modality Therapy; COVID-19; COVID-19 Serotherapy; Diabetes Mellitus,

2021
The future of community nursing: Hospital in the Home.
    British journal of community nursing, 2017, Apr-02, Volume: 22, Issue:4

    Topics: Acute Disease; Aged; Anti-Bacterial Agents; Bronchodilator Agents; Clergy; Community Health Nursing;

2017
Reexpansion Pulmonary Edema as a Complication of Endobronchial Valve Placement.
    Journal of bronchology & interventional pulmonology, 2017, Volume: 24, Issue:4

    Topics: Aged; Bronchoscopy; Diuretics; Emphysema; Female; Furosemide; Humans; Oxyhemoglobins; Pulmonary Atel

2017
Furosemide nebulization in patients with COPD exacerbation--reply.
    Respiratory care, 2014, Volume: 59, Issue:3

    Topics: Bronchoconstriction; Female; Furosemide; Humans; Male; Pulmonary Disease, Chronic Obstructive

2014
Furosemide Nebulization in Patients With COPD Exacerbation.
    Respiratory care, 2014, Volume: 59, Issue:3

    Topics: Bronchoconstriction; Female; Furosemide; Humans; Male; Pulmonary Disease, Chronic Obstructive

2014
The importance of identifying the association between metabolic alkalosis and respiratory acidosis.
    Archivos de bronconeumologia, 2012, Volume: 48, Issue:2

    Topics: Acetazolamide; Acidosis, Respiratory; Alkalosis; Bicarbonates; Furosemide; Humans; Obesity Hypoventi

2012
Breathlessness in cancer patients.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:8

    Topics: Administration, Inhalation; Analgesics, Opioid; Benzodiazepines; Bronchodilator Agents; Chemorecepto

2008
Effects of acetazolamide and furosemide on ventilation and cerebral blood volume in normocapnic and hypercapnic patients with COPD.
    Chest, 2002, Volume: 121, Issue:2

    Topics: Acetazolamide; Administration, Oral; Alkalosis; Blood Volume; Carbon Dioxide; Cerebrovascular Circul

2002