furosemide has been researched along with Puerperal Disorders in 12 studies
Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
Puerperal Disorders: Disorders or diseases associated with PUERPERIUM, the six-to-eight-week period immediately after PARTURITION in humans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness of furosemide in accelerating blood pressure recovery among women with severe preeclampsia." | 5.20 | Diuretics vs. placebo for postpartum blood pressure control in preeclampsia (DIUPRE): a randomized clinical trial. ( Amorim, M; Coutinho, I; Cursino, T; Katz, L, 2015) |
| " She was treated because of low left ventricular ejection fraction and impression of postpartum cardiomyopathy, and her severe dyspnea improved by intravenous furosemide." | 4.02 | Severe acute respiratory syndrome coronavirus-2- or pregnancy-related cardiomyopathy, a differential to be considered in the current pandemic: a case report. ( Hajizadeh, R; Kavandi, H; Khademolhosseini, S; Nejadrahim, R, 2021) |
| "Echocardiography showed 73% dilated cardiomyopathy; 83% showed moderate to severe LV systolic dysfunction (mean EF 36." | 1.43 | Clinical and echocardiographic characteristics and outcomes in congestive heart failure at the Hospital of The State University of Haiti. ( Malebranche, R; Morisset, PH; Raphael, NA; Tabou Moyo, C; Wilentz, JR, 2016) |
| "Anemia, hypertension and rheumatic fever were the causes of heart failure in these 3 patients, but they were not apparent when the initial diagnosis was made." | 1.31 | [Peripartum heart failure: the underestimated role of frequent diseases in the Sudan-Sahelian area]. ( Ba, SA; Dia, AA; Diop, IB; Diouf, SM; Kane, A; Sarr, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Nejadrahim, R | 1 |
| Khademolhosseini, S | 1 |
| Kavandi, H | 1 |
| Hajizadeh, R | 1 |
| Cursino, T | 1 |
| Katz, L | 1 |
| Coutinho, I | 1 |
| Amorim, M | 1 |
| Malebranche, R | 1 |
| Tabou Moyo, C | 1 |
| Morisset, PH | 1 |
| Raphael, NA | 1 |
| Wilentz, JR | 1 |
| Veena, P | 1 |
| Perivela, L | 1 |
| Raghavan, SS | 1 |
| Kim, DY | 1 |
| Islam, S | 1 |
| Mondal, NT | 1 |
| Mussell, F | 1 |
| Rauchholz, M | 1 |
| Kane, A | 1 |
| Dia, AA | 1 |
| Diop, IB | 1 |
| Sarr, M | 1 |
| Ba, SA | 1 |
| Diouf, SM | 1 |
| Marcovici, I | 1 |
| Gerhardt, S | 1 |
| Turpin, S | 1 |
| Lambert, R | 1 |
| Querin, S | 1 |
| Soulez, G | 1 |
| Leveille, J | 1 |
| Taillefer, R | 1 |
| Sullivan, JM | 1 |
| Palmer, ET | 1 |
| Schoeneberger, AA | 1 |
| Jennings, JC | 1 |
| Morrison, JC | 1 |
| Ratts, TE | 1 |
| Neill, P | 1 |
| Donadio, JV | 1 |
| Holley, KE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Postpartum Furosemide on Recovery Blood Pressure in Puerperal Women With Severe Preeclampsia: a Randomized Clinical Trial[NCT02163655] | Phase 4 | 120 participants (Actual) | Interventional | 2014-03-31 | Completed | ||
| Lasix for the Prevention of De Novo Postpartum Hypertension: A Randomized Controlled Trial (LAPP Trial)[NCT04752475] | Phase 3 | 82 participants (Actual) | Interventional | 2021-10-20 | Completed | ||
| Postpartum Management of Gestational Hypertensive Disorders Using Furosemide: A Randomized Controlled Trial[NCT04343235] | Phase 4 | 13 participants (Actual) | Interventional | 2020-05-01 | Terminated (stopped due to Challenges with enrollment; primary investigator left the institution) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Difference in MAP averaged over the 24 hours prior to discharge or the 24 hours prior to antihypertensive therapy initiation (whichever occurs first) (NCT04752475)
Timeframe: 24 hours prior to discharge through discharge, up to 7 days
| Intervention | mmHg (Mean) |
|---|---|
| Lasix (Furosemide) | 88.9 |
| Placebo | 86.8 |
breastfeeding continuation after discharge (NCT04343235)
Timeframe: at 1 week postpartum visit
| Intervention | Participants (Count of Participants) |
|---|---|
| Labetalol + Furosemide | 1 |
| Labetalol Only | 3 |
number of patients who require a change in the dose of labetalol to control BP (NCT04343235)
Timeframe: Change in dose of hypertensive therapy from randomization until hospital discharge (up to 7 days)
| Intervention | Participants (Count of Participants) |
|---|---|
| Labetalol + Furosemide | 3 |
| Labetalol Only | 0 |
days in hospital after delivery (NCT04343235)
Timeframe: Number of days of hospital stay from randomization to discharge
| Intervention | days (Mean) |
|---|---|
| Labetalol + Furosemide | 3.5 |
| Labetalol Only | 4.3 |
readmission for hypertension management (NCT04343235)
Timeframe: up to 14 days after discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Labetalol + Furosemide | 1 |
| Labetalol Only | 2 |
average diastolic blood pressure reading on Day 0, Day 1, and Day 2 (NCT04343235)
Timeframe: Average diastolic blood pressure on Day 0, Day 1, and Day 2
| Intervention | mm of mercury (Mean) | ||
|---|---|---|---|
| Day 0 | Day 1 | Day 2 | |
| Labetalol + Furosemide | 84.1 | 81.8 | 78.8 |
| Labetalol Only | 80.1 | 80.7 | 75.5 |
average mean arterial pressure reading on Day 0, Day 1, and Day 2 (NCT04343235)
Timeframe: Average mean arterial pressure on Day 0, Day 1, and Day 2
| Intervention | mm of mercury (Mean) | ||
|---|---|---|---|
| Day 0 | Day 1 | Day 2 | |
| Labetalol + Furosemide | 102.4 | 99.5 | 98.0 |
| Labetalol Only | 100.0 | 100.1 | 96.0 |
average systolic blood pressure reading on Day 0, Day 1, and Day 2 (NCT04343235)
Timeframe: Average systolic blood pressure for Day 0, Day 1, and Day 2
| Intervention | mm of mercury (Mean) | ||
|---|---|---|---|
| Day 0 | Day 1 | Day 2 | |
| Labetalol + Furosemide | 138.4 | 134.9 | 135.2 |
| Labetalol Only | 138.1 | 138.2 | 136.7 |
2 trials available for furosemide and Puerperal Disorders
| Article | Year |
|---|---|
Diuretics vs. placebo for postpartum blood pressure control in preeclampsia (DIUPRE): a randomized clinical trial.
Topics: Blood Pressure; Diuretics; Eclampsia; Female; Furosemide; Humans; Hypertension; Length of Stay; Magn | 2015 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Ni | 2017 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Ni | 2017 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Ni | 2017 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Ni | 2017 |
10 other studies available for furosemide and Puerperal Disorders
| Article | Year |
|---|---|
Severe acute respiratory syndrome coronavirus-2- or pregnancy-related cardiomyopathy, a differential to be considered in the current pandemic: a case report.
Topics: Adult; Anti-Bacterial Agents; Antiviral Agents; Azithromycin; Cardiomyopathies; Cesarean Section; Co | 2021 |
Clinical and echocardiographic characteristics and outcomes in congestive heart failure at the Hospital of The State University of Haiti.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Age Distribution; Aged; Aged, 80 and over; Angiotens | 2016 |
Biventricular thrombi associated with peripartum cardiomyopathy.
Topics: Bangladesh; Cardiomyopathies; Drug Combinations; Echocardiography; Enalapril; Female; Furosemide; Hu | 2011 |
[Peripartum heart failure: the underestimated role of frequent diseases in the Sudan-Sahelian area].
Topics: Adult; Africa, Northern; Anemia; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiotonic Ag | 2000 |
Postpartum preeclampsia management with furosemide: a randomized clinical trial.
Topics: Diuretics; Female; Furosemide; Humans; Pancreatitis; Postpartum Period; Pre-Eclampsia; Pregnancy; Pu | 2005 |
[Genesis and therapy of postpartum carpal tunnel syndrome].
Topics: Adult; Carpal Tunnel Syndrome; Edema; Female; Furosemide; Humans; Lactation; Pregnancy; Puerperal Di | 1984 |
Radionuclide captopril renography in postpartum renal artery aneurysms.
Topics: Adult; Aneurysm; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Female; Furosemide; | 1996 |
SQ 20,881: effect on eclamptic--pre-eclamptic women with postpartum hypertension.
Topics: Adolescent; Adult; Angiotensin II; Eclampsia; Female; Furosemide; Hemodynamics; Humans; Hypertension | 1978 |
Axillary vein thrombosis complicating peripartum congestive cardiomyopathy.
Topics: Adult; Axillary Vein; Cardiomyopathy, Dilated; Female; Follow-Up Studies; Furosemide; Heparin; Human | 1987 |
Postpartum acute renal failure: recovery after heparin therapy.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Biopsy; Cesarean Section; Creatinine; Disseminated In | 1974 |