Page last updated: 2024-10-27

furosemide and Muscle Relaxation

furosemide has been researched along with Muscle Relaxation in 13 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"In principal ponies with airway obstruction, furosemide administration significantly decreased pulmonary resistance and increased dynamic compliance, but had no effect on PaO2 or PaCO2."5.28Effects of furosemide on ponies with recurrent airway obstruction. ( Broadstone, RV; Derksen, FJ; Gray, PR; Robinson, NE; Woods, PS, 1991)
"Amiloride treatment reduced the increase in epithelial ion content but had no effect on shrinkage or SNP-induced relaxation."1.33Effects of hyperosmolarity and airway epithelial ion transport inhibitors on sodium nitroprusside-induced relaxation of guinea pig trachea. ( Hedenstierna, G; Hjoberg, J; Högman, M; Ljung, L; Roomans, GM, 2005)
"Furosemide was unable to reduce 86Rb uptake at 10 mM [Cl-], although relaxation was still observed in 10 mM [Cl-]."1.30Furosemide-induced airway relaxation in guinea pigs: relation to Na-K-2Cl cotransporter function. ( Claybaugh, JR; Dressel, MV; Iwamoto, LM; Lavallee, SL; Nakamura, KT; Sato, AK, 1997)
"Pretreatment with furosemide diminished relaxation response to salbutamol [87 +/- 3% (n = 11) vs."1.30Cross-desensitization to furosemide and salbutamol in isolated neonatal guinea pig airways. ( Christ, MJ; Fujiwara, N; Gelber, RP; Iwamoto, LM; Marinkovich, GA; Nakamura, KT, 1999)
"Furosemide has recently been shown to be effective in inhibiting various indirect challenges in asthmatic patients, but its mode of action is not yet clear."1.29Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro. ( Demedts, MG; Pype, JL; Verleden, GM, 1994)
"In principal ponies with airway obstruction, furosemide administration significantly decreased pulmonary resistance and increased dynamic compliance, but had no effect on PaO2 or PaCO2."1.28Effects of furosemide on ponies with recurrent airway obstruction. ( Broadstone, RV; Derksen, FJ; Gray, PR; Robinson, NE; Woods, PS, 1991)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's9 (69.23)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hjoberg, J1
Högman, M1
Hedenstierna, G1
Ljung, L1
Roomans, GM1
Sugiyama, M1
Fukumi, H1
Grammer, RT1
Misono, KS1
Yabe, Y1
Morisawa, Y1
Inagami, T1
Greenberg, S1
McGowan, C1
Xie, J1
Summer, WR1
Verleden, GM1
Pype, JL1
Demedts, MG1
Souhrada, M1
Souhrada, JF1
Greenwood, IA1
Hogg, RC1
Large, WA1
Almirall, JJ1
Dolman, CS1
Eidelman, DH1
Lavallee, SL1
Iwamoto, LM3
Claybaugh, JR1
Dressel, MV1
Sato, AK1
Nakamura, KT3
Gelber, RP1
Christ, MJ1
Marinkovich, GA1
Fujiwara, N1
Gries, DM1
Lonigro, AJ1
Hagemann, MH1
Stephenson, AH1
Merle, CL1
Broadstone, RV1
Robinson, NE1
Gray, PR1
Woods, PS1
Derksen, FJ1
Tian, R1
Aalkjaer, C1
Andreasen, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Retrospective Chart Review Evaluating the Impact of Steroid, Diuretic, and Fluid Use Practice Trends in Extreme Premature Infants at Risk for Bronchopulmonary Dysplasia (BPD) at a Single Center Neonatal Intensive Care Unit[NCT04971694]175 participants (Anticipated)Observational2021-09-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

13 other studies available for furosemide and Muscle Relaxation

ArticleYear
Effects of hyperosmolarity and airway epithelial ion transport inhibitors on sodium nitroprusside-induced relaxation of guinea pig trachea.
    Respiratory physiology & neurobiology, 2005, Apr-15, Volume: 146, Issue:2-3

    Topics: Amiloride; Analysis of Variance; Animals; Connective Tissue; Drug Interactions; Endothelium-Dependen

2005
Synthesis of atrial natriuretic peptides and studies on structural factors in tissue specificity.
    Biochemical and biophysical research communications, 1984, Aug-30, Volume: 123, Issue:1

    Topics: Animals; Aorta; Atrial Natriuretic Factor; Carbachol; Chickens; Chromatography, High Pressure Liquid

1984
Selective pulmonary and venous smooth muscle relaxation by furosemide: a comparison with morphine.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: Animals; Arteries; Biological Transport; Chlorides; Dogs; Endothelium, Vascular; Female; Furosemide;

1994
Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Animals; Arginine; Atropine; Bumetanide; Chymotrypsin; Drug Therapy, Combination; Electric Stimulati

1994
Inhibitory effect of staurosporine on protein kinase C stimulation of airway smooth muscle cells.
    The American review of respiratory disease, 1993, Volume: 148, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Alkaloids; Amiloride; Animals; Car

1993
Effect of frusemide, ethacrynic acid and indanyloxyacetic acid on spontaneous Ca-activated currents in rabbit portal vein smooth muscle cells.
    British journal of pharmacology, 1995, Volume: 115, Issue:5

    Topics: Animals; Calcium; Chloride Channels; Diuretics; Ethacrynic Acid; Female; Furosemide; Glycolates; In

1995
Furosemide-induced bronchodilation in the rat bronchus: evidence of a role for prostaglandins.
    Lung, 1997, Volume: 175, Issue:3

    Topics: Animals; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Diuretics;

1997
Furosemide-induced airway relaxation in guinea pigs: relation to Na-K-2Cl cotransporter function.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Animals; Animals, Newborn; Biological Transport; Bumetanide; Carrier Proteins; Chlorides; Epithelium

1997
Cross-desensitization to furosemide and salbutamol in isolated neonatal guinea pig airways.
    Biology of the neonate, 1999, Volume: 76, Issue:2

    Topics: Acetylcholine; Albuterol; Animals; Animals, Newborn; Bronchodilator Agents; Cyclic AMP; Drug Toleran

1999
Loop diuretics and in vitro relaxation of human fetal and newborn mouse airways.
    Pediatric research, 2001, Volume: 50, Issue:2

    Topics: Animals; Animals, Newborn; Bronchi; Bumetanide; Diuretics; Fetus; Furosemide; Humans; In Vitro Techn

2001
Furosemide exhibits physicochemical properties similar to prostaglandins and interferes with their bioassay.
    Prostaglandins, 1978, Volume: 16, Issue:2

    Topics: Animals; Biological Assay; Chromatography, Thin Layer; Colon; Dogs; Dose-Response Relationship, Drug

1978
Effects of furosemide on ponies with recurrent airway obstruction.
    Pulmonary pharmacology, 1991, Volume: 4, Issue:4

    Topics: Aerosols; Airway Obstruction; Airway Resistance; Animals; Furosemide; Horse Diseases; Horses; Inject

1991
Mechanisms behind the relaxing effect of furosemide on the isolated rabbit ear artery.
    Pharmacology & toxicology, 1990, Volume: 67, Issue:5

    Topics: Animals; Arteries; Calcium; Cell Membrane; Ear, External; Electric Stimulation; Endothelium, Vascula

1990