Page last updated: 2024-10-27

furosemide and Liver Dysfunction

furosemide has been researched along with Liver Dysfunction in 54 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"Combined use of furosemide with albumin is an approved therapy to overcome diuretic resistance in treatment of ascites in decompensated chronic liver disease."9.34Comparative Study of Slow Infusion versus Bolus Doses of Albumin and Furosemide Infusion to Mobilize Refractory Ascites in Decompensated Chronic Liver Disease. ( Jha, A; Kafle, B; Khadga, P; Pathak, R; Thapaliya, S; Yadav, AK, 2020)
"Among 459 patients with hepatic edema enrolled in a retrospective, multicenter collaborative study, we analyzed 407 patients who received tolvaptan."7.96Analysis of factors associated with the prognosis of cirrhotic patients who were treated with tolvaptan for hepatic edema. ( Abe, H; Arai, T; Atsukawa, M; Chuma, M; Fukunishi, S; Hattori, N; Hiraoka, A; Iio, E; Ikegami, T; Itokawa, N; Iwakiri, K; Iwasa, M; Kato, K; Kondo, C; Kumada, T; Michitaka, K; Nakagawa-Iwashita, A; Nozaki, A; Okubo, H; Okubo, T; Senoh, T; Tada, T; Takaguchi, K; Takei, Y; Tanaka, Y; Tani, J; Toyoda, H; Tsubota, A; Tsutsui, A; Uojima, H; Watanabe, T; Yokohama, K; Yoshida, Y, 2020)
" We present the case of a patient with hypoxic hepatitis in the setting of heart failure and dehydration from furosemide as a reminder of an important clinical lesson."7.88Hypoxic hepatitis and furosemide. ( Pizzarossa, AC; Rebella, M, 2018)
"Furosemide occasionally causes azotemia in patients with ascites, independently of induced volume depletion."7.67Immediate effects of furosemide on renal hemodynamics in chronic liver disease with ascites. ( Daskalopoulos, G; Harley, H; Laffi, G; Morgan, T; Pinzani, M; Reynolds, T; Zipser, RD, 1987)
"Combined use of furosemide with albumin is an approved therapy to overcome diuretic resistance in treatment of ascites in decompensated chronic liver disease."5.34Comparative Study of Slow Infusion versus Bolus Doses of Albumin and Furosemide Infusion to Mobilize Refractory Ascites in Decompensated Chronic Liver Disease. ( Jha, A; Kafle, B; Khadga, P; Pathak, R; Thapaliya, S; Yadav, AK, 2020)
"Furosemide (frusemide) is a potent loop diuretic used in the treatment of oedematous states associated with cardiac, renal and hepatic failure, and for the treatment of hypertension."4.78Furosemide (frusemide). A pharmacokinetic/pharmacodynamic review (Part I). ( Ponto, LL; Schoenwald, RD, 1990)
" Some examples such as the modification of furosemide pharmacokinetics in acute renal failure, the impaired metabolism of opiate analgesics in hepatic insufficiency, the alterations of the usual disposition process in salicylic acid intoxication, and the influence of cardiac failure upon some drugs pharmacokinetics, have been chosen to illustrate some of the aspects discussed."4.76Disease-induced modifications of drug pharmacokinetics. ( Barre, J; Bree, F; Brunner, F; Houin, G; Tillement, JP, 1983)
"Among 459 patients with hepatic edema enrolled in a retrospective, multicenter collaborative study, we analyzed 407 patients who received tolvaptan."3.96Analysis of factors associated with the prognosis of cirrhotic patients who were treated with tolvaptan for hepatic edema. ( Abe, H; Arai, T; Atsukawa, M; Chuma, M; Fukunishi, S; Hattori, N; Hiraoka, A; Iio, E; Ikegami, T; Itokawa, N; Iwakiri, K; Iwasa, M; Kato, K; Kondo, C; Kumada, T; Michitaka, K; Nakagawa-Iwashita, A; Nozaki, A; Okubo, H; Okubo, T; Senoh, T; Tada, T; Takaguchi, K; Takei, Y; Tanaka, Y; Tani, J; Toyoda, H; Tsubota, A; Tsutsui, A; Uojima, H; Watanabe, T; Yokohama, K; Yoshida, Y, 2020)
" We present the case of a patient with hypoxic hepatitis in the setting of heart failure and dehydration from furosemide as a reminder of an important clinical lesson."3.88Hypoxic hepatitis and furosemide. ( Pizzarossa, AC; Rebella, M, 2018)
" Kinetic parameters were determined in plasma and urine; further, in patients with liver cirrhosis, renal elimination kinetics of the diuretic were correlated with the concentration of direct plasma bilirubin, as a marker of cholestasis, at the beginning of a treatment with xipamide, 40 mg qd."3.73[Mechanism of action of xipamide and its classification as a "low ceiling diuretic". Pharmacodynamic-pharmacokinetic studies in healthy volunteers and in kidney and liver patients]. ( Knauf, H; Mutschler, E, 2005)
"Furosemide occasionally causes azotemia in patients with ascites, independently of induced volume depletion."3.67Immediate effects of furosemide on renal hemodynamics in chronic liver disease with ascites. ( Daskalopoulos, G; Harley, H; Laffi, G; Morgan, T; Pinzani, M; Reynolds, T; Zipser, RD, 1987)
"Furosemide-induced (400mg/kg ip) hepatotoxicity progressing to centrilobular necrosis was studied by light and electron microscopy in Swiss white mice."3.66Furosemide induced hepatotoxicity. ( McElligott, TF; Walker, RM, 1981)
"The binding of three loop diuretics, piretanide, bumetanide and furosemide, to serum proteins from patients with liver cirrhosis or fulminant hepatitis was investigated using equilibrium dialysis."3.66Further investigations on the binding of loop diuretics to serum proteins from patients with liver disease. ( Fujii, S; Fujiwara, K; Goto, S; Miyamoto, A; Nakayama, T; Yamada, H; Yoshitomi, H, 1981)
"Five patients with hepatorenal syndrome were treated with a LeVeen peritoneovenous shunt and furosemide."3.66Treatment of hepatorenal syndrome. ( Schwartz, ML; Vogel, SB, 1980)
"Drug-induced hepatic encephalopathy was more common in cirrhotics receiving diuretics (13."1.27An intensive drug monitoring study suggesting possible clinical irrelevance of impaired drug disposition in liver disease. ( Busto, U; Janecek, E; Kaplan, K; Naranjo, CA; Roach, CA; Ruiz, I, 1983)
" The dosage of furosemide did not account for the increased frequency of ARs in patients with hepatic disease."1.26Furosemide-induced adverse reactions during hospitalization. ( Busto, U; Cassis, L; Naranjo, CA, 1978)
"Phenformin treatment should be avoided in case of renal and/or liver insufficiency."1.25Phenformin-induced lactic acidosis in diabetic patients. ( Assan, R; Attali, JR; Girard, JR; Heuclin, C; LeMaire, F, 1975)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199044 (81.48)18.7374
1990's2 (3.70)18.2507
2000's4 (7.41)29.6817
2010's2 (3.70)24.3611
2020's2 (3.70)2.80

Authors

AuthorsStudies
Atsukawa, M1
Tsubota, A1
Takaguchi, K1
Toyoda, H1
Iwasa, M1
Ikegami, T1
Chuma, M1
Nozaki, A1
Uojima, H1
Hiraoka, A1
Fukunishi, S1
Yokohama, K1
Tada, T1
Kato, K1
Abe, H1
Tani, J1
Okubo, H1
Watanabe, T1
Hattori, N1
Tsutsui, A1
Senoh, T1
Yoshida, Y1
Okubo, T1
Itokawa, N1
Nakagawa-Iwashita, A1
Kondo, C1
Arai, T1
Michitaka, K1
Iio, E1
Kumada, T1
Tanaka, Y1
Takei, Y1
Iwakiri, K1
Pathak, R1
Yadav, AK1
Thapaliya, S1
Kafle, B1
Jha, A1
Khadga, P1
Pizzarossa, AC1
Rebella, M1
Eshar, D1
Peddle, GD1
Briscoe, JA1
CANTERINANTONINI, S1
CANTERINANTONINI, A1
PAGANO, G1
PISANO, E1
PELLEGRINI, A1
Knauf, H1
Mutschler, E1
Kobayashi, C1
Sasaki, H1
Kosuge, K1
Miyakita, Y1
Hayakawa, M1
Suzuki, A1
Abe, E1
Suzuki, K1
Aizawa, Y1
Di Costanzo, GG1
Ragozzino, A1
Niola, R1
Maglione, F1
Ascione, A1
Arai, A1
Yan, W1
Wakabayashi, S1
Hayashi, S1
Inazawa, J1
Miura, O1
Pupita, F2
Bartoli, E1
Molaschi, M1
Schnitzler, R1
Fritz, KW1
Barre, J1
Houin, G1
Brunner, F1
Bree, F1
Tillement, JP1
Naranjo, CA2
Busto, U2
Janecek, E1
Ruiz, I1
Roach, CA1
Kaplan, K1
Goto, S2
Yoshitomi, H2
Miyamoto, A2
Inoue, K1
Nakano, M1
Walker, RM1
McElligott, TF1
Yamada, H1
Fujii, S1
Nakayama, T1
Fujiwara, K1
Schwartz, ML1
Vogel, SB1
García Puig, J1
Mateos Anton, F1
Anciones, B1
Grande, C1
Gilaquado, A1
Arnalich, F1
Barbado, J1
Vázquez, JJ1
Gisbert, P1
Martin, P1
Casares, M1
Riñón, M1
Ortíz Vázquez, J1
Montero García, A1
Jolobe, OM1
Epstien, M1
Blendis, LM1
Greig, PD1
Langer, B1
Baigrie, RS1
Ruse, J1
Taylor, BR1
Dreux, C1
Passa, P1
Halter, D1
McMurtry, RJ1
Mitchell, JR2
Cassis, L1
Borirakchanyavat, V1
Sitprija, V1
Luke, RG1
Assan, R1
Heuclin, C1
Girard, JR1
LeMaire, F1
Attali, JR1
Spitznagle, LA1
Wirth, PJ1
Boobis, SW1
Thorgeirsson, SS1
Nelson, WL1
Thiele, KG1
Wilmink, JM1
Snodgrass, WR1
Gillette, JR1
Danks, DM1
Ponto, LL1
Schoenwald, RD1
Viani, A1
Carrai, M1
Pacifici, GM1
Huang, Y1
Kamiya, A1
Hayashi, Y1
Inui, K1
Hori, R1
Daskalopoulos, G1
Laffi, G1
Morgan, T1
Pinzani, M1
Harley, H1
Reynolds, T1
Zipser, RD1
Pockros, PJ1
Reynolds, TB1
Campolucci, G1
Pulido, M1
Belogi, M1
Rotatori, P1
Ansuini, R1
Frausini, G1
Barone, A1
Gaggi, S1
Siciński, A1
Horrobin, DF1
Manku, MS1
Nassar, BA1
Dzúriková, V1
Brixová, E1
Niederland, TR1
Reubi, FC1
Klebanoff, G1
Hollander, D1
Cosimi, AB1
Stanford, W1
Kemmerer, WT1
Szende, L1
Radó, J1
Takó, J1
Cohn, JN1
Tristani, FE1
Khatri, IM1
Szám, I1
Gläsel, E1
Gentili, G1
Liberti, R1
Klütsch, K1
Pickert, H1
Müller, K1
Henning, H1
Steigmann, F1
Oz, R1
Dubin, A1
Terrasse, J1
Derycke, C1
Marcheix, JC1
Kuzmanic, A1
Faivovich, A1
Del Rio, R1
Jaruffe, F1
Vera, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bioequivalence Study of Furosemide in Indonesian Healthy Volunteers[NCT04982874]24 participants (Actual)Interventional2019-12-13Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Geometric Mean Ratio of Area Under Curve

The ratio between test drug and reference drug (NCT04982874)
Timeframe: before dosing (0 h) and at 0.25, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, 10, 12, 16 and 24 hours after drug administration

Interventionpercentage (Geometric Mean)
Furosemide 40 mg Tablet101.79

Geometric Mean Ratio of Maximum Concentration

The ratio between test drug and reference drug (NCT04982874)
Timeframe: before dosing (0 h) and at 0.25, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, 10, 12, 16 and 24 hours after drug administration

Interventionpercentage (Geometric Mean)
Furosemide 40 mg Tablet104.51

Pharmacokinetics Parameter

Area Under Curve from 0 to 24 hours (NCT04982874)
Timeframe: before dosing (0 h) and at 0.25, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, 10, 12, 16 and 24 hours after drug administration

Interventionng*h/mL (Mean)
Furosemide 40 mg Tablet4938.79
Lasix® 40 mg Tablet4921.94

Pharmacokinetics Parameter

Maximum plasma concentration (NCT04982874)
Timeframe: before dosing (0 h) and at 0.25, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, 10, 12, 16 and 24 hours after drug administration

Interventionng/mL (Mean)
Furosemide 40 mg Tablet1893.09
Lasix® 40 mg Tablet1907.32

Reviews

7 reviews available for furosemide and Liver Dysfunction

ArticleYear
Successful imatinib treatment of cardiac involvement of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia followed by severe hepatotoxicity.
    International journal of hematology, 2007, Volume: 86, Issue:3

    Topics: Adult; Antineoplastic Agents; Benzamides; Biopsy; Chemical and Drug Induced Liver Injury; Chromosome

2007
Disease-induced modifications of drug pharmacokinetics.
    International journal of clinical pharmacology research, 1983, Volume: 3, Issue:4

    Topics: Acute Kidney Injury; Blood Proteins; Disease; Furosemide; Glomerular Filtration Rate; Heart Failure;

1983
Deranged renal function in liver disease.
    Contributions to nephrology, 1977, Volume: 7

    Topics: Angiotensin II; Diet, Sodium-Restricted; Furosemide; Humans; Hyperaldosteronism; Kidney; Kidney Dise

1977
Diagnostic possibilities in acute renal failure.
    Geriatrics, 1976, Volume: 31, Issue:8

    Topics: Acute Kidney Injury; Blood Circulation; Blood Urea Nitrogen; Blood Volume; Extracellular Space; Furo

1976
Furosemide (frusemide). A pharmacokinetic/pharmacodynamic review (Part I).
    Clinical pharmacokinetics, 1990, Volume: 18, Issue:5

    Topics: Acute Kidney Injury; Furosemide; Heart Failure; Humans; Hypertension; Liver Diseases

1990
[Advances in nephrology. Chronic renal failure].
    Polskie Archiwum Medycyny Wewnetrznej, 1974, Volume: 52, Issue:2

    Topics: Bone and Bones; Cataract; Deafness; Female; Furosemide; Gastrointestinal Diseases; Humans; Hypercalc

1974
Combination diuretic drug therapy.
    Cardiovascular clinics, 1971, Volume: 2, Issue:3

    Topics: Amiloride; Benzothiadiazines; Diet; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Furosemid

1971

Trials

1 trial available for furosemide and Liver Dysfunction

ArticleYear
Comparative Study of Slow Infusion versus Bolus Doses of Albumin and Furosemide Infusion to Mobilize Refractory Ascites in Decompensated Chronic Liver Disease.
    Journal of Nepal Health Research Council, 2020, Sep-07, Volume: 18, Issue:2

    Topics: Albumins; Ascites; Furosemide; Humans; Infusions, Intravenous; Liver Diseases; Nepal

2020

Other Studies

46 other studies available for furosemide and Liver Dysfunction

ArticleYear
Analysis of factors associated with the prognosis of cirrhotic patients who were treated with tolvaptan for hepatic edema.
    Journal of gastroenterology and hepatology, 2020, Volume: 35, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Diuretics; Drug Therapy, Combination; Edema; Female; Furosemide; Hum

2020
Hypoxic hepatitis and furosemide.
    BMJ case reports, 2018, Sep-30, Volume: 2018

    Topics: Chemical and Drug Induced Liver Injury; Dehydration; Diagnosis, Differential; Diuretics; Echocardiog

2018
Diagnosis and treatment of congestive heart failure secondary to hypertrophic cardiomyopathy in a kinkajou (Potos flavus).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2010, Volume: 41, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Infective Agents; Cardiomyopathy, Hypertroph

2010
[FIRST EXPERIENCES WITH A NEW DIURETIC: FUROSEMIDE].
    Minerva medica, 1965, May-19, Volume: 56

    Topics: Diuretics; Furosemide; Heart Diseases; Humans; Liver Diseases

1965
[CLINICAL EXPERIENCES WITH A NEW SYNTHETIC DIURETIC: FUROSEMIDE].
    La Clinica terapeutica, 1965, Jun-30, Volume: 33

    Topics: Diuretics; Furosemide; Heart Diseases; Hypertension; Liver Diseases

1965
[Mechanism of action of xipamide and its classification as a "low ceiling diuretic". Pharmacodynamic-pharmacokinetic studies in healthy volunteers and in kidney and liver patients].
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:1

    Topics: Bilirubin; Cholestasis; Creatinine; Diet, Sodium-Restricted; Diuresis; Diuretics; Furosemide; Glomer

2005
Severe starvation hypoglycemia and congestive heart failure induced by thyroid crisis, with accidentally induced severe liver dysfunction and disseminated intravascular coagulation.
    Internal medicine (Tokyo, Japan), 2005, Volume: 44, Issue:3

    Topics: Aged; Blood Glucose; Blood Pressure; Chemical and Drug Induced Liver Injury; Disseminated Intravascu

2005
A rare cause of diuretic refractory ascites.
    Gut, 2006, Volume: 55, Issue:1

    Topics: Ascites; Constriction, Pathologic; Cysts; Diuretics; Female; Furosemide; Humans; Liver Diseases; Mag

2006
[Recent advances in the physiopathology and therapy of edematogenic states].
    La Clinica terapeutica, 1966, Nov-30, Volume: 39, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Digitalis Glycosides; Diuretics; Edema; Female; Furosemide; Heart Fa

1966
[A comparative clinical investigation of the diuretic furosemide].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:5

    Topics: Acute Kidney Injury; Benzothiadiazines; Chlorides; Diuretics; Eclampsia; Edema; Female; Furosemide;

1966
An intensive drug monitoring study suggesting possible clinical irrelevance of impaired drug disposition in liver disease.
    British journal of clinical pharmacology, 1983, Volume: 15, Issue:4

    Topics: Brain Diseases; Diuretics; Drug Evaluation; Drug-Related Side Effects and Adverse Reactions; Furosem

1983
Binding of several loop diuretics to serum albumin and human serum from patients with renal failure and liver disease.
    Journal of pharmacobio-dynamics, 1980, Volume: 3, Issue:12

    Topics: Adult; Animals; Blood Proteins; Bumetanide; Cattle; Diuretics; Female; Furosemide; Humans; Kidney Fa

1980
Furosemide induced hepatotoxicity.
    The Journal of pathology, 1981, Volume: 135, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Erythrocytes; Furosemide; Liver; Liver Diseases; Ma

1981
Further investigations on the binding of loop diuretics to serum proteins from patients with liver disease.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:11

    Topics: Adult; Bilirubin; Blood Proteins; Bumetanide; Diuretics; Female; Furosemide; Hepatitis; Humans; Live

1981
Treatment of hepatorenal syndrome.
    American journal of surgery, 1980, Volume: 139, Issue:3

    Topics: Adult; Ascites; Ascitic Fluid; Creatine; Furosemide; Humans; Infusions, Parenteral; Kidney Diseases;

1980
[Influence of furosemide on the acidifying dysfunction of renal tubular acidosis].
    Revista clinica espanola, 1980, Mar-31, Volume: 156, Issue:6

    Topics: Acidosis, Renal Tubular; Chronic Disease; Diuresis; Furosemide; Humans; Hydrogen-Ion Concentration;

1980
Efficacy of low-dose captopril in addition to furosemide and spironolactone in patients with decompensated liver disease during blunted diuresis.
    Journal of hepatology, 1993, Volume: 19, Issue:2

    Topics: Aged; Captopril; Diuresis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Furo

1993
The renal and hemodynamic effects of the peritoneovenous shunt for intractable hepatic ascites.
    Gastroenterology, 1979, Volume: 77, Issue:2

    Topics: Adult; Aged; Aldosterone; Ascites; Body Weight; Budd-Chiari Syndrome; Cardiac Output; Diuresis; Drai

1979
Influence of hepatic insufficiency in pharmacokinetics of drugs: example for an anthranilic diuretic.
    Methods and findings in experimental and clinical pharmacology, 1979, Volume: 1, Issue:5

    Topics: Adult; Aged; Furosemide; Humans; Kinetics; Liver Cirrhosis; Liver Diseases; Middle Aged; Pharmaceuti

1979
Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridine.
    Toxicology and applied pharmacology, 1977, Volume: 42, Issue:2

    Topics: Animals; Cephaloridine; Chemical and Drug Induced Liver Injury; Furans; Furosemide; In Vitro Techniq

1977
Furosemide-induced adverse reactions during hospitalization.
    American journal of hospital pharmacy, 1978, Volume: 35, Issue:7

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Child; Chile; Dose-Response Relationship, Drug; Dr

1978
Frusemide in liver diseases with renal failure.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1978, Volume: 61, Issue:9

    Topics: Acute Kidney Injury; Adult; Aged; Furosemide; Hepatitis A; Humans; Liver Cirrhosis; Liver Diseases;

1978
Phenformin-induced lactic acidosis in diabetic patients.
    Diabetes, 1975, Volume: 24, Issue:9

    Topics: Adult; Aged; Bicarbonates; Blood Glucose; Carbon Dioxide; Diabetes Mellitus; Diabetic Ketoacidosis;

1975
The role of biliary excretion in the hepatotoxicity of furosemide in the mouse.
    Toxicology and applied pharmacology, 1977, Volume: 39, Issue:2

    Topics: Animals; Autoradiography; Bile; Blood Proteins; Chemical and Drug Induced Liver Injury; Furosemide;

1977
[Renal disorders in hepatic insufficiency - pathogenesis and therapy (author's transl)].
    Leber, Magen, Darm, 1977, Volume: 7, Issue:4

    Topics: Acute Kidney Injury; Blood Volume; Furosemide; Glomerular Filtration Rate; Humans; Kidney; Kidney Tu

1977
Some clinical aspects of acute renal failure.
    The Netherlands journal of medicine, 1977, Volume: 20, Issue:4-5

    Topics: Acute Kidney Injury; Anuria; Furosemide; Glomerulonephritis; Humans; Liver Diseases; Mannitol; Nephr

1977
The role of biotransformation in chemical-induced liver injury.
    Environmental health perspectives, 1976, Volume: 15

    Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cr

1976
Letter: Diuretic therapy in infants and children.
    The Journal of pediatrics, 1976, Volume: 88, Issue:4

    Topics: Child; Furosemide; Humans; Infant; Liver Diseases; Spironolactone

1976
Plasma protein binding of frusemide in liver disease: effect of hypoalbuminaemia and hyperbilirubinaemia.
    British journal of clinical pharmacology, 1989, Volume: 28, Issue:2

    Topics: Adult; Aged; Blood Proteins; Dialysis; Female; Furosemide; Humans; Hyperbilirubinemia; Liver Disease

1989
Decreased diuretic response to furosemide in rats with acute hepatic failure.
    Journal of pharmacobio-dynamics, 1988, Volume: 11, Issue:8

    Topics: Adrenalectomy; Aldosterone; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; D

1988
Immediate effects of furosemide on renal hemodynamics in chronic liver disease with ascites.
    Gastroenterology, 1987, Volume: 92, Issue:6

    Topics: Ascites; Blood Pressure; Chronic Disease; Furosemide; Hemodynamics; Humans; Inulin; Kidney; Liver Di

1987
Rapid diuresis in patients with ascites from chronic liver disease: the importance of peripheral edema.
    Gastroenterology, 1986, Volume: 90, Issue:6

    Topics: Amiloride; Ascites; Body Weight; Chronic Disease; Diuresis; Edema; Electrolytes; Furosemide; Humans;

1986
[Indications for therapy with diuretics].
    La Clinica terapeutica, 1985, Oct-15, Volume: 115, Issue:1

    Topics: Aldosterone; Blood Volume; Cardiac Output; Diuretics; Edema; Edema, Cardiac; Furosemide; Humans; Kid

1985
Letter: Hepatorenal syndrome and prolactin.
    The New England journal of medicine, 1974, Feb-14, Volume: 290, Issue:7

    Topics: Animals; Furosemide; Humans; Kidney Diseases; Liver Diseases; Prolactin; Rats; Syndrome

1974
[Effect of single administration of furosemide in patients with chronic liver disease].
    Bratislavske lekarske listy, 1974, Volume: 61, Issue:3

    Topics: Chronic Disease; Furosemide; Humans; Hyperglycemia; Liver Diseases

1974
Asanguineous hypothermic total body perfusion (TBW) in the treatment of stage IV hepatic coma.
    The Journal of surgical research, 1972, Volume: 12, Issue:1

    Topics: Autopsy; Biopsy; Blood Chemical Analysis; Blood Gas Analysis; Blood Pressure Determination; Blood Tr

1972
[Clinico-pharmacological studies of furosemide].
    Orvosi hetilap, 1971, Oct-24, Volume: 112, Issue:43

    Topics: Furosemide; Glomerular Filtration Rate; Heart Diseases; Humans; Kidney Diseases; Liver Diseases; Nat

1971
Renal vasodilator therapy in the hepatorenal syndrome.
    The Medical annals of the District of Columbia, 1970, Volume: 39, Issue:1

    Topics: Furosemide; Humans; Kidney Diseases; Liver Diseases; Male; Middle Aged; Vasodilator Agents

1970
[Prevention and therapy of hepatic coma].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1970, Volume: 30, Issue:1

    Topics: Aged; Amides; Ammonia; Aspartic Acid; Chlorothiazide; Clopamide; Depression, Chemical; Diuretics; Fe

1970
[Clinical aspect and therapy of a severe acute dinitroorthocresol poisoning].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Apr-15, Volume: 25, Issue:8

    Topics: Acidosis; Adenosine Triphosphate; Adult; Bicarbonates; Bloodletting; Brain Edema; Carbohydrates; Cre

1970
[Clinical study of the use of "Spirolang" 50].
    Minerva medica, 1971, Feb-28, Volume: 62, Issue:17

    Topics: Adult; Aged; Ascites; Chronic Disease; Digitalis Glycosides; Diuresis; Electrolytes; Ethacrynic Acid

1971
[Treatment of the so-called hepatorenal syndrome].
    Deutsche medizinische Wochenschrift (1946), 1968, Jun-14, Volume: 93, Issue:24

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Diet, Sodium-Restricted; Dietary Carbohydrates; Dietary

1968
[The effect of furosemide on the liver function].
    Therapie der Gegenwart, 1966, Volume: 105, Issue:2

    Topics: Adult; Aged; Female; Furosemide; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Liver Function

1966
Newer diuretics in the treatment of cardiac or hepatic disease in elderly patients.
    Journal of the American Geriatrics Society, 1966, Volume: 14, Issue:12

    Topics: Ascites; Benzothiadiazines; Blood Glucose; Blood Urea Nitrogen; Body Weight; Cardiovascular Diseases

1966
[Study of a diuretic, furosemide, in hospital practice].
    Semaine therapeutique, 1966, Volume: 42, Issue:9

    Topics: Edema; Furosemide; Heart Diseases; Humans; Liver Diseases; Obesity

1966
[Experience with a new diuretic Furosemide].
    Revista medica de Chile, 1966, Volume: 94, Issue:9

    Topics: Edema; Furosemide; Heart Failure; Humans; Kidney Diseases; Liver Diseases

1966