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furosemide and Insulin Resistance

furosemide has been researched along with Insulin Resistance in 6 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"Spironolactone, not furosemide, improved insulin resistance in CHF patients probably by the inhibition of inflammatory cytokines and MMPs."9.19Spironolactone, not furosemide, improved insulin resistance in patients with chronic heart failure. ( Anker, SD; Doehner, W; Hisatome, I; Kato, M; Kinugasa, Y; Ogino, K; Yamamoto, K, 2014)
" We conducted a well-controlled study in 12 insulin-resistant nondiabetic participants, who received treatment for 9 weeks with either rosiglitazone at a dosage of 4 mg b."6.76Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover study. ( Deen, PM; Li, Y; Masereeuw, R; Rennings, AJ; Russel, FG; Smits, P; Tack, CJ, 2011)
"Spironolactone, not furosemide, improved insulin resistance in CHF patients probably by the inhibition of inflammatory cytokines and MMPs."5.19Spironolactone, not furosemide, improved insulin resistance in patients with chronic heart failure. ( Anker, SD; Doehner, W; Hisatome, I; Kato, M; Kinugasa, Y; Ogino, K; Yamamoto, K, 2014)
" HF-fed rats had impaired glucose tolerance, increased urine excretion of 8-isoprostane (a marker of oxidative stress), increased protein levels for NKCC2 (50-125%) and the renal outer medullary potassium channel (106%), as well as increased natriuretic response to furosemide (20-40%)."3.75Abundance of the Na-K-2Cl cotransporter NKCC2 is increased by high-fat feeding in Fischer 344 X Brown Norway (F1) rats. ( Ecelbarger, CM; Rash, A; Riazi, S; Sharma, N; Tiwari, S, 2009)
" It is possible that these factors may play a role in changes in insulin sensitivity in vivo produced by such diverse conditions as treatment with furosemide, thyroid status or catecholamine status."3.68Some experiments on factors that can change insulin sensitivity. ( Newsholme, EA, 1990)
" We conducted a well-controlled study in 12 insulin-resistant nondiabetic participants, who received treatment for 9 weeks with either rosiglitazone at a dosage of 4 mg b."2.76Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover study. ( Deen, PM; Li, Y; Masereeuw, R; Rennings, AJ; Russel, FG; Smits, P; Tack, CJ, 2011)
"Only clonidine treatment totally prevented the development of insulin resistance, and high-dose aspirin, known to prevent insulin resistance by inhibition of the activity of IkappaB kinase-beta, decreased the degree of insulin resistance by almost 70%."1.32Hypertension and insulin resistance are not directly related in obese dogs. ( Gokee, A; Rocchini, AP; Yang, JQ, 2004)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ogino, K1
Kinugasa, Y1
Kato, M1
Yamamoto, K1
Hisatome, I1
Anker, SD1
Doehner, W1
Riazi, S1
Tiwari, S1
Sharma, N1
Rash, A1
Ecelbarger, CM1
Rennings, AJ1
Russel, FG1
Li, Y1
Deen, PM1
Masereeuw, R1
Tack, CJ1
Smits, P1
Rocchini, AP1
Yang, JQ1
Gokee, A1
Newsholme, EA1
Schwarzbach, W1
Haas, W1

Trials

2 trials available for furosemide and Insulin Resistance

ArticleYear
Spironolactone, not furosemide, improved insulin resistance in patients with chronic heart failure.
    International journal of cardiology, 2014, Feb-15, Volume: 171, Issue:3

    Topics: Aged; Blood Glucose; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Furosemide; H

2014
Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover study.
    Clinical pharmacology and therapeutics, 2011, Volume: 89, Issue:4

    Topics: Adult; Amiloride; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Interactions; Epithelial

2011

Other Studies

4 other studies available for furosemide and Insulin Resistance

ArticleYear
Abundance of the Na-K-2Cl cotransporter NKCC2 is increased by high-fat feeding in Fischer 344 X Brown Norway (F1) rats.
    American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:4

    Topics: Animals; Antioxidants; Biomarkers; Blood Pressure; Blotting, Western; Crosses, Genetic; Cyclic N-Oxi

2009
Hypertension and insulin resistance are not directly related in obese dogs.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Rest

2004
Some experiments on factors that can change insulin sensitivity.
    Annals of medicine, 1990, Volume: 22, Issue:3

    Topics: Adenosine; Animals; Body Temperature Regulation; Catecholamines; Furosemide; Glucose; Humans; Insuli

1990
[Saluretic therapy and insulin resistance in diabetes mellitus].
    Medizinische Klinik, 1966, Dec-23, Volume: 61, Issue:51

    Topics: Aged; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Female; Furosemide; Humans; Hyponatr

1966