Page last updated: 2024-10-27

furosemide and Infant, Newborn, Diseases

furosemide has been researched along with Infant, Newborn, Diseases in 27 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.

Research Excerpts

ExcerptRelevanceReference
"In an attempt to explore the possible role of prolactin (PRL) in the control of neonatal electrolyte homeostasis, this study has been carried out to compare plasma electrolyte concentrations, urine volume and urinary electrolyte excretion as well as plasma PRL levels in healthy full-term neonates with idiopathic edema prior to and after furosemide treatment."7.67Plasma prolactin levels in full-term newborn infants with idiopathic edema: response to furosemide. ( Bódis, J; Csaba, IF; Ertl, T; Sulyok, E, 1986)
"In an attempt to explore the possible role of prolactin (PRL) in the control of neonatal electrolyte homeostasis, this study has been carried out to compare plasma electrolyte concentrations, urine volume and urinary electrolyte excretion as well as plasma PRL levels in healthy full-term neonates with idiopathic edema prior to and after furosemide treatment."3.67Plasma prolactin levels in full-term newborn infants with idiopathic edema: response to furosemide. ( Bódis, J; Csaba, IF; Ertl, T; Sulyok, E, 1986)
"Subcutaneous fat necrosis of the newborn is an uncommon, self-limiting panniculitis that usually occurs in full-term infants as a consequence of perinatal asphyxia."1.33Subcutaneous fat necrosis of the newborn: be aware of hypercalcaemia. ( Borgia, F; Cacace, C; Cannavo, SP; De Pasquale, L; Guarneri, C; Meo, P, 2006)
"Symptomatic patent ductus arteriosus (sPDA) may occur in up to 50% of very-low-birth-weight (VLBW, less than or equal to 1500 g) infants."1.28Symptomatic patent ductus arteriosus in very-low-birth-weight infants: 1987-1989. ( Mouzinho, AI; Risser, R; Rosenfeld, CR, 1991)
" for therapeutic reasons, the elimination kinetics appeared to follow a two-compartment open model, with a significant difference in the therminal plasma half-life between premature (26."1.26Pharmacokinetics of furosemide in neonates. ( Broquaire, M; Legagneur, M; Morselli, PL; Vert, P, 1982)
"Furosemide is an effective diuretic, the onset of pharmacologic action was within one hour, the peak action was sustained for three hours, and the duration of action was six hours."1.26The pharmacologic effects of furosemide therapy in the low-birth-weight infant. ( Oh, W; Pollak, A; Ross, BS, 1978)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199021 (77.78)18.7374
1990's3 (11.11)18.2507
2000's1 (3.70)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Capozza, M1
Chinellato, I1
Guarnieri, V1
Di Lorgi, N1
Accadia, M1
Traggiai, C1
Mattioli, G1
Di Mauro, A1
Laforgia, N1
Segar, JL1
Borgia, F1
De Pasquale, L1
Cacace, C1
Meo, P1
Guarneri, C1
Cannavo, SP1
Kassner, EG1
Tuck, S1
Morselli, P1
Broquaire, M2
Vert, P2
Zenk, KE1
Legagneur, M1
Morselli, PL1
Oh, W2
Guignard, JP2
Dubourg, L1
Gouyon, JB2
Scales, JW1
Krowchuk, DP1
Schwartz, RP1
Jorizzo, JL1
Ross, BS1
Pollak, A1
Woo, WC1
Dupont, C1
Collinge, J1
Aranda, JV3
Cohen, S1
Neims, AH1
Cowan, RH1
Waldo, AL1
Harris, HB1
Cassady, G1
Brans, YW1
Loggie, JM1
Kleinman, LI1
Van Maanen, EF1
Mouzinho, AI1
Rosenfeld, CR1
Risser, R1
Chemtob, S1
Laudignon, N1
Sasyniuk, BI1
Ertl, T1
Sulyok, E1
Bódis, J1
Csaba, IF1
Nouaille, J1
Solc, J1
Knorr, D1
Robertson, NR1
Guerricchio, G1
Van der Horst, RL1
Richardson, H1
Sacrez, R1
Geisert, J1
Willard, D1
Plöchl, E1
Stur, O1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease[NCT01721655]Phase 2/Phase 340 participants (Anticipated)Interventional2012-10-31Recruiting
A Retrospective Chart Review Evaluating the Impact of Steroid, Diuretic, and Fluid Use Practice Trends in Extreme Premature Infants at Risk for Bronchopulmonary Dysplasia (BPD) at a Single Center Neonatal Intensive Care Unit[NCT04971694]175 participants (Anticipated)Observational2021-09-08Recruiting
Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis[NCT02469597]Phase 246 participants (Actual)Interventional2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Length of Hospital Stay

(NCT02469597)
Timeframe: Participants will be followed for the duration of hospital stay up to 1 week

InterventionDays (Least Squares Mean)
Single Dose of Furosemide3.1
Placebo3.0

Oxygen Saturation

(NCT02469597)
Timeframe: 2 hours after medication adminstration

InterventionPercentage change in oxygen saturation (Least Squares Mean)
Single Dose of Furosemide-0.14
Placebo0.2

Oxygen Saturation

(NCT02469597)
Timeframe: 4 hours after medication adminstration

InterventionPercentage change in oxygen saturation (Least Squares Mean)
Single Dose of Furosemide-0.19
Placebo0.29

Patient Needing Endotracheal Intubation

(NCT02469597)
Timeframe: Within 72 hours of medication administration

Interventionparticipants (Number)
Single Dose of Furosemide0
Placebo0

Respiratory Rate

(NCT02469597)
Timeframe: 2 hours after medication adminstration

InterventionPercentage change in respiratory rate (Least Squares Mean)
Single Dose of Furosemide-3.7
Placebo-1.7

Respiratory Rate

(NCT02469597)
Timeframe: 4 hours after medication adminstration

InterventionPercentage change in respiratory rate (Least Squares Mean)
Single Dose of Furosemide-2.8
Placebo-5.4

Reviews

5 reviews available for furosemide and Infant, Newborn, Diseases

ArticleYear
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
    Clinics in perinatology, 2012, Volume: 39, Issue:1

    Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor

2012
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
    Clinics in perinatology, 2012, Volume: 39, Issue:1

    Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor

2012
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
    Clinics in perinatology, 2012, Volume: 39, Issue:1

    Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor

2012
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
    Clinics in perinatology, 2012, Volume: 39, Issue:1

    Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor

2012
An overview of perinatal clinical pharmacology.
    Clinics in laboratory medicine, 1981, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digo

1981
[Diuretics in the neonatal period].
    Revue medicale de la Suisse romande, 1995, Volume: 115, Issue:8

    Topics: Benzothiadiazines; Bronchopulmonary Dysplasia; Diuretics; Furosemide; Heart Failure; Humans; Infant,

1995
Adverse effects of drugs on the immature kidney.
    Biology of the neonate, 1988, Volume: 53, Issue:4

    Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Female; Fetus; Furosemide; Glome

1988
Furosemide and vitamin E. Two problem drugs in neonatology.
    Pediatric clinics of North America, 1986, Volume: 33, Issue:3

    Topics: Acid-Base Imbalance; Anemia; Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Diuresis; Ductus Arter

1986

Other Studies

22 other studies available for furosemide and Infant, Newborn, Diseases

ArticleYear
Case report: acute clinical presentation and neonatal management of primary hyperparathyroidism due to a novel CaSR mutation.
    BMC pediatrics, 2018, 10-30, Volume: 18, Issue:1

    Topics: Bone Density Conservation Agents; Calcimimetic Agents; Cinacalcet; Clodronic Acid; Diphosphonates; F

2018
Subcutaneous fat necrosis of the newborn: be aware of hypercalcaemia.
    Journal of paediatrics and child health, 2006, Volume: 42, Issue:5

    Topics: Asphyxia Neonatorum; Fat Necrosis; Female; Furosemide; Humans; Hypercalcemia; Infant, Newborn; Infan

2006
New drugs, more complications--old drugs, new complications: drug-related sequelae of neonatal intensive care.
    Bulletin of the New York Academy of Medicine, 1984, Volume: 60, Issue:5

    Topics: Bezoars; Critical Care; Drug-Related Side Effects and Adverse Reactions; Furosemide; Humans; Hyperte

1984
Plasma and urinary kinetics of furosemide in newborn infants.
    The Journal of pediatrics, 1983, Volume: 103, Issue:3

    Topics: Furosemide; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kinetics; Water-Electroly

1983
Pharmacokinetics of furosemide in neonates.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Female; Furosemide; Gestational Age; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases;

1982
Renal functions and clinical disorders in the neonate.
    Clinics in perinatology, 1981, Volume: 8, Issue:2

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Asphyxia Neonatorum; Furosemide; Humans; Indomethacin; I

1981
An infant with firm, fixed plaques.
    Archives of dermatology, 1998, Volume: 134, Issue:4

    Topics: Failure to Thrive; Fat Necrosis; Female; Fluid Therapy; Furosemide; Glucocorticoids; Humans; Hyperca

1998
The pharmacologic effects of furosemide therapy in the low-birth-weight infant.
    The Journal of pediatrics, 1978, Volume: 92, Issue:1

    Topics: Furosemide; Heart Failure; Humans; Hydrogen-Ion Concentration; Infant; Infant, Low Birth Weight; Inf

1978
Effects of furosemide in the newborn.
    Clinical pharmacology and therapeutics, 1978, Volume: 23, Issue:3

    Topics: Body Water; Chlorides; Diuresis; Electrolytes; Furosemide; Humans; Infant; Infant, Newborn; Infant,

1978
Drug utilization in a newborn intensive care unit.
    The Journal of pediatrics, 1976, Volume: 89, Issue:2

    Topics: Ampicillin; Bicarbonates; Birth Weight; Canada; Chloramphenicol; Drug Therapy, Combination; Drug Uti

1976
Neonatal paroxysmal supraventricular tachycardia with hydrops.
    Pediatrics, 1975, Volume: 55, Issue:3

    Topics: Digoxin; Edema; Electrocardiography; Female; Fetal Diseases; Furosemide; Heart Ventricles; Humans; I

1975
Renal function and diuretic therapy in infants and children. Part III.
    The Journal of pediatrics, 1975, Volume: 86, Issue:6

    Topics: Adolescent; Calcium; Child; Child, Preschool; Diuresis; Diuretics; Edema; Ethacrynic Acid; Female; F

1975
Symptomatic patent ductus arteriosus in very-low-birth-weight infants: 1987-1989.
    Early human development, 1991, Volume: 27, Issue:1-2

    Topics: Analysis of Variance; Cardiac Surgical Procedures; Colloids; Ductus Arteriosus, Patent; Female; Flui

1991
Plasma prolactin levels in full-term newborn infants with idiopathic edema: response to furosemide.
    Biology of the neonate, 1986, Volume: 49, Issue:1

    Topics: Diuresis; Edema; Furosemide; Humans; Infant, Newborn; Infant, Newborn, Diseases; Potassium; Prolacti

1986
[Medical treatment of heart failure in infants and young children].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Jan-20, Volume: 45, Issue:4

    Topics: Anti-Bacterial Agents; Anticoagulants; Aortic Coarctation; Bradycardia; Chlorothiazide; Diet, Sodium

1969
[Investigation on tetrahydroaldosterone excretion in childhood using gas chromatography with an electron capture detector].
    Acta endocrinologica, 1972, Volume: 70, Issue:3

    Topics: Addison Disease; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Age Factors; Aldosterone; Ang

1972
Prolonged continuous positive airways pressure for pulmonary oedema due to persistent ductus arteriosus in the newborn.
    Archives of disease in childhood, 1974, Volume: 49, Issue:7

    Topics: Carbon Dioxide; Cardiac Catheterization; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Infa

1974
[Wolff-Parkinson-White syndrome and paroxysmal tachycardia in infants. (Apropos of a case)].
    Minerva cardioangiologica, 1972, Volume: 20, Issue:1

    Topics: Ajmaline; Digoxin; Electrocardiography; Furosemide; Humans; Infant, Newborn; Infant, Newborn, Diseas

1972
Congenital atrial flutter and cardiac failure presenting as hydrops foetalis at birth.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Sep-12, Volume: 44, Issue:36

    Topics: Atrial Flutter; Birth Weight; Body Weight; Digoxin; Edema; Electrocardiography; Female; Fetal Diseas

1970
Frusemide in heart failure of infancy.
    Archives of disease in childhood, 1971, Volume: 46, Issue:248

    Topics: Administration, Oral; Aortic Coarctation; Body Weight; Chlorides; Ductus Arteriosus, Patent; Female;

1971
[Place of new diuretics in the treatment of some neonatal diseases].
    Annales de pediatrie, 1969, Jan-02, Volume: 16, Issue:1

    Topics: Brain Edema; Diuresis; Edema; Ethacrynic Acid; Furosemide; Humans; Infant, Newborn; Infant, Newborn,

1969
[Sweat studies in renal diabetes insipidus during treatment with saluretics].
    Helvetica paediatrica acta, 1965, Volume: 20, Issue:4

    Topics: Chlorides; Chlorthalidone; Diabetes Insipidus; Diuretics; Furosemide; Humans; Infant, Newborn; Infan

1965