Page last updated: 2024-10-27

furosemide and Inappropriate ADH Syndrome

furosemide has been researched along with Inappropriate ADH Syndrome in 46 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.

Research Excerpts

ExcerptRelevanceReference
" The experimental SIADH rat model was developed by means of continuous administration of arginine vasopressin (AVP) via a subcutaneously implanted osmotic mini pump, and hyponatremia was induced by additional water loading."7.74A novel vasopressin dual V1A/V2 receptor antagonist, conivaptan hydrochloride, improves hyponatremia in rats with syndrome of inappropriate secretion of antidiuretic hormone (SIADH). ( Arai, Y; Fujimori, A; Matsukawa, U; Miyata, K; Sasamata, M; Sudoh, K; Wada, K, 2007)
" Followed by hydration with saline, pamidronate is effective for the control of symptomatic hypercalcemia."4.79[Paraneoplastic syndrome]. ( Hara, N; Nakanishi, Y; Takayama, K, 1997)
" The experimental SIADH rat model was developed by means of continuous administration of arginine vasopressin (AVP) via a subcutaneously implanted osmotic mini pump, and hyponatremia was induced by additional water loading."3.74A novel vasopressin dual V1A/V2 receptor antagonist, conivaptan hydrochloride, improves hyponatremia in rats with syndrome of inappropriate secretion of antidiuretic hormone (SIADH). ( Arai, Y; Fujimori, A; Matsukawa, U; Miyata, K; Sasamata, M; Sudoh, K; Wada, K, 2007)
"We report a case of lateral medullary syndrome showing syndrome of inappropriate secretion of antidiuretic hormone and analyze the pathomechanism underlying its clinical features."2.53Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with lateral medullary syndrome: case report and literature review. ( Nakano, H; Yamada, M; Yanase, D, 2016)
"SIADH is underdiagnosed, and hospitalization often worsens the clinical situation, due to an iatrogenic excess in the use of oral and i."2.46[Current considerations in syndrome of inappropriate secretion of antidiuretic hormone/syndrome of inappropriate antidiuresis]. ( Runkle de la Vega, I; Velasco Cano, MV, 2010)
"Hyponatremia is the most common electrolyte abnormality."2.44[Etiology, diagnostics and therapy of hyponatremias]. ( Laczi, F, 2008)
"Although, pharmacological intervention with a selective arginine vasopressin (AVP) V(2) receptor antagonist has been demonstrated to be effective for syndrome of inappropriate secretion of antidiuretic hormone (SIADH), its long-term administration has some therapeutic limitations."1.34Lithium effectively complements vasopressin V2 receptor antagonist in the treatment of hyponatraemia of SIADH rats. ( Arata, T; Ejima, Y; Hatano, R; Kazama, I; Matsubara, M; Michimata, M; Miyama, N; Sanada, S; Sasaki, S; Sato, A; Satomi, S; Suzuki, M, 2007)
"Severe hyponatremia is most frequently caused by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)."1.33BSC1 inhibition complements effects of vasopressin V2 receptor antagonist on hyponatremia in SIADH rats. ( Arata, T; Ejima, Y; Hatano, R; Kazama, I; Matsubara, M; Michimata, M; Miyama, N; Sasaki, S; Sato, A; Satomi, S; Suzuki, K; Suzuki, M, 2005)
"We report a case of hyponatremic seizures in a 7-year old boy with spina bifida following cystoscopy and suprapubic catheter placement."1.33Hyponatremic seizures after suprapubic catheter placement in 7-year-old child. ( Camporesi, EM; Puskas, F; Sweeney, DM; Szolnoki, JM; Upadhyay, J, 2006)
"Oliguria is common in critically ill patients and may result from prerenal, renal, and postrenal causes."1.28Oliguria in patients with normal renal function. ( Hughes, SS; Zaloga, GP, 1990)
"Hyponatremia should be considered when seizures or mental changes occur in patients treated with DDP."1.27Cis-dichlorodiammineplatinum II-induced syndrome of inappropriate secretion of antidiuretic hormone. ( Ritch, PS, 1988)
" We describe the clinical course and management of each patient, including the long-term use of furosemide taken orally once a day."1.27Chronic syndrome of inappropriate secretion of antidiuretic hormone in childhood. ( David, R; Fertig, A; Sklar, C, 1985)
"Because hyponatremia is frequently associated with preceding diuretic treatment and unrestricted fluid intake--conditions which have not been addressed sufficiently in published literature--we studied the pathophysiology and the clinical setting of such hyponatremia in a large group of internal medicine patients."1.27Role of diuretics, hormonal derangements, and clinical setting of hyponatremia in medical patients. ( Gross, P; Hackenthal, E; Hausmann, C; Ketteler, M; Rascher, W; Reinhard, C; Ritz, E; Schömig, A, 1988)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199018 (39.13)18.7374
1990's6 (13.04)18.2507
2000's12 (26.09)29.6817
2010's8 (17.39)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Garrahy, A1
Sherlock, M1
Thompson, CJ1
Noppakun, K1
Pin-On, P1
Ruengorn, C1
Runkle, I1
Villabona, C1
Navarro, A1
Pose, A1
Formiga, F1
Tejedor, A1
Poch, E1
Cil, O1
Esteva-Font, C1
Tas, ST1
Su, T1
Lee, S1
Anderson, MO1
Ertunc, M1
Verkman, AS1
Filippatos, TD1
Liamis, G1
Elisaf, MS1
Genoni, T1
Tenconi, R1
Bertolozzi, G1
Laicini, EA1
Tardini, G1
Vianello, F1
Leva, E1
Milani, GP1
Fossali, EF1
Nakano, H1
Yanase, D1
Yamada, M1
Laczi, F1
Alilou, M1
Awab, A1
Zarouf, M1
Moussaoui, RE1
Hijri, AE1
Azzouzi, A1
Slaoui, A1
Velasco Cano, MV1
Runkle de la Vega, I1
Varsavsky, M1
Quesada Charneco, M1
Rozas Moreno, P1
Vandergheynst, F1
Brachet, C1
Heinrichs, C1
Decaux, G5
Prasad, NK1
Balkiran, V1
Kumar, BS1
Agrawal, R1
Babu, BK1
Kumar, VS1
López Montes, A1
Lorenzo, I1
Pérez Martínez, J1
Kazama, I2
Hatano, R2
Michimata, M2
Suzuki, K1
Arata, T2
Suzuki, M2
Miyama, N2
Sato, A2
Satomi, S2
Ejima, Y2
Sasaki, S2
Matsubara, M2
Szolnoki, JM1
Puskas, F1
Sweeney, DM1
Camporesi, EM1
Upadhyay, J1
Sanada, S1
Mukoyama, M1
Nakao, K1
Wada, K1
Matsukawa, U1
Fujimori, A1
Arai, Y1
Sudoh, K1
Sasamata, M1
Miyata, K1
Abramow, M2
Cogan, E2
Iwasa, H1
Yamada, T1
Nakahara, N1
Shimabukuro, H1
Shinoda, S1
Indei, I1
Yamada, N1
Sato, F1
Saito, T1
Hsieh, BS1
Frontera Izquierdo, P1
Cabezuelo Huerta, G1
Carles Genovés, C1
Waterlot, Y2
Genette, F2
Hallemans, R1
Demanet, JC1
Gross, P2
Handelman, W1
Schrier, RW1
Moses, AM1
Notman, DD1
Weizman, Z1
Goitein, K1
Amit, Y1
Wald, U1
Landau, H1
Espí, F1
Fernández, MI1
Tebar, J1
Soriano, J1
Ascaso, JF1
Carmena, R1
Dratwa, M1
Mockel, J1
Miller, M1
Elisaf, M1
Siamopoulos, KC1
Nakanishi, Y1
Takayama, K1
Hara, N1
Hartung, TK1
Fredlund, VG1
Abdel Samie, A1
Theilmann, L1
Friedman, AL1
Segar, WE1
Shalev, O1
Naparstek, Y1
Brezis, M1
Ben-Yishai, D1
Wachsberg, RH1
Kurtz, AB1
Putterman, C1
Almog, Y1
Caraco, Y1
Gross, DJ1
Ben-Chetrit, E1
Zaloga, GP1
Hughes, SS1
Ritch, PS1
Sklar, C1
Fertig, A1
David, R1
Ketteler, M1
Hausmann, C1
Reinhard, C1
Schömig, A1
Hackenthal, E1
Ritz, E1
Rascher, W1
Okada, Y1
Minematsu, K1
Miyashita, T1
Yamaguchi, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Urea for Chronic Hyponatremia: A Pilot Study[NCT04588207]Phase 22 participants (Actual)Interventional2021-12-28Terminated (stopped due to Unable to recruit participants)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for furosemide and Inappropriate ADH Syndrome

ArticleYear
Ten pitfalls in the proper management of patients with hyponatremia.
    Postgraduate medicine, 2016, Volume: 128, Issue:5

    Topics: Acute Disease; Antidiuretic Hormone Receptor Antagonists; Chronic Disease; Diuretics; Drug Dosage Ca

2016
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with lateral medullary syndrome: case report and literature review.
    BMC neurology, 2016, Jul-27, Volume: 16

    Topics: Aged; Antipyrine; Arginine; Clopidogrel; Diffusion Magnetic Resonance Imaging; Diuretics; Edaravone;

2016
[Etiology, diagnostics and therapy of hyponatremias].
    Orvosi hetilap, 2008, Jul-20, Volume: 149, Issue:29

    Topics: Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Benzazepines; Blood Volume; Brain D

2008
[Current considerations in syndrome of inappropriate secretion of antidiuretic hormone/syndrome of inappropriate antidiuresis].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2010, Volume: 57 Suppl 2

    Topics: Aging; Aquaporin 2; Arginine Vasopressin; Blood Volume; Brain Edema; Combined Modality Therapy; Diag

2010
Long-term treatment of hyponatremic patients with nephrogenic syndrome of inappropriate antidiuresis: personal experience and review of published case reports.
    Nephron. Clinical practice, 2012, Volume: 120, Issue:3

    Topics: Adult; Aged; Diuretics; Furosemide; Genetic Diseases, X-Linked; Humans; Hyponatremia; Inappropriate

2012
[Syndrome of inappropriate secretion of antidiuretic hormone].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1

    Topics: Central Nervous System Diseases; Chlorpropamide; Diagnosis, Differential; Furosemide; Humans; Inappr

2006
Clinical aspects and pathophysiology of diuretic-induced hyponatremia.
    Advances in nephrology from the Necker Hospital, 1984, Volume: 13

    Topics: Age Factors; Aged; Benzothiadiazines; Body Water; Body Weight; Diuretics; Female; Furosemide; Humans

1984
[Evaluation and treatment of hyponatremia (author's transl)].
    Klinische Wochenschrift, 1980, Feb-15, Volume: 58, Issue:4

    Topics: Furosemide; Heart Failure; Humans; Hypertonic Solutions; Hyponatremia; Inappropriate ADH Syndrome; I

1980
Diabetes insipidus and syndrome of inappropriate antidiuretic hormone secretion (SIADH).
    Advances in internal medicine, 1982, Volume: 27

    Topics: Anti-Inflammatory Agents; Chlorpropamide; Diabetes Insipidus; Female; Furosemide; Humans; Inappropri

1982
[Paraneoplastic syndrome].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24 Suppl 3

    Topics: Alendronate; Anticoagulants; Cushing Syndrome; Diagnosis, Differential; Diphosphonates; Disseminated

1997

Other Studies

36 other studies available for furosemide and Inappropriate ADH Syndrome

ArticleYear
Treatment Outcomes in Syndrome of Inappropriate Antidiuresis: Improvements in Hyponatremia May Reflect Successful Treatment or Resolution of the Underlying Cause.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020, Volume: 76, Issue:4

    Topics: Furosemide; Humans; Hyponatremia; Inappropriate ADH Syndrome; Sodium Chloride; Treatment Outcome

2020
In Reply to 'Treatment Outcomes in Syndrome of Inappropriate Antidiuresis: Improvements in Hyponatremia May Reflect Successful Treatment or Resolution of the Underlying Cause'.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020, Volume: 76, Issue:4

    Topics: Furosemide; Humans; Hyponatremia; Inappropriate ADH Syndrome; Sodium Chloride; Treatment Outcome

2020
[The treament of hyponatremia secundary to the syndrome of inappropriate antidiuretic hormone secretion].
    Medicina clinica, 2013, Dec-07, Volume: 141, Issue:11

    Topics: Acute Disease; Algorithms; Benzazepines; Combined Modality Therapy; Decision Support Techniques; Flu

2013
Salt-sparing diuretic action of a water-soluble urea analog inhibitor of urea transporters UT-A and UT-B in rats.
    Kidney international, 2015, Volume: 88, Issue:2

    Topics: Animals; Binding Sites; Disease Models, Animal; Diuresis; Diuretics; Dogs; Drug Evaluation, Preclini

2015
Treatment of Severe Hypervolemic Hyponatremia in a Child With Pneumonia.
    Pediatric emergency care, 2016, Volume: 32, Issue:6

    Topics: Diagnosis, Differential; Diuretics; Fluid Therapy; Furosemide; Humans; Hyponatremia; Inappropriate A

2016
[Severe hyponatraemia secondary to cure of cyclophosphamide (about three cases)].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Behcet Syndrome; Cyclophosphamide; Diuretics; Female; Furo

2009
[Urea as therapeutic option for the treatment of the syndrome of inappropriate antidiuretic hormone secretion].
    Medicina clinica, 2011, Jul-23, Volume: 137, Issue:5

    Topics: Amitriptyline; Carbamazepine; Comorbidity; Demeclocycline; Diabetic Neuropathies; Diuretics; Furosem

2011
"Euvolemic hyponatremia"--3 case reports and approach to management.
    Indian journal of medical sciences, 2002, Volume: 56, Issue:3

    Topics: Aged; Aged, 80 and over; Diuretics; Female; Furosemide; Humans; Hyponatremia; Inappropriate ADH Synd

2002
[Porphyria and inappropriate antidiuretic hormone syndrome].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24 Suppl 3

    Topics: Abdominal Pain; Adult; Aminolevulinic Acid; Coproporphyrins; Diuretics; Endometriosis; Female; Furos

2004
BSC1 inhibition complements effects of vasopressin V2 receptor antagonist on hyponatremia in SIADH rats.
    Kidney international, 2005, Volume: 67, Issue:5

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aquaporin 2; Aquaporins; Benzazepines; Deamino A

2005
Hyponatremic seizures after suprapubic catheter placement in 7-year-old child.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:2

    Topics: Abdominal Wall; Anticonvulsants; Catheterization; Child; Cystoscopy; Diuretics; Furosemide; Glucose;

2006
Lithium effectively complements vasopressin V2 receptor antagonist in the treatment of hyponatraemia of SIADH rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:1

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aquaporin 2; Benzazepines; Diabetes Insipidus, N

2007
A novel vasopressin dual V1A/V2 receptor antagonist, conivaptan hydrochloride, improves hyponatremia in rats with syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Disease Mode

2007
[Marked effect of furosemide and hypertonic saline in the treatment of SIAD after head injury].
    No shinkei geka. Neurological surgery, 1984, Volume: 12, Issue:5

    Topics: Adult; Brain Neoplasms; Combined Modality Therapy; Furosemide; Humans; Hyponatremia; Inappropriate A

1984
Prostaglandin E--vasopressin interrelation in the syndrome of inappropriate secretion of antidiuretic hormone.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1983, Volume: 82, Issue:4

    Topics: Adult; Aged; Arginine Vasopressin; Body Water; Female; Furosemide; Humans; Inappropriate ADH Syndrom

1983
Treatment of the syndrome of inappropriate secretion of antidiuretic hormone by long loop diuretics.
    Nephron, 1983, Volume: 35, Issue:2

    Topics: Adolescent; Aged; Diuresis; Ethacrynic Acid; Female; Furosemide; Humans; Inappropriate ADH Syndrome;

1983
[Syndrome of inappropriate secretion of antidiuretic hormone in children (author's transl)].
    Anales espanoles de pediatria, 1981, Volume: 15, Issue:3

    Topics: Child; Furosemide; Hormones, Ectopic; Humans; Hypothalamus; Inappropriate ADH Syndrome; Lithium; Lit

1981
Inappropriate secretion of antidiuretic hormone treated with frusemide.
    British medical journal (Clinical research ed.), 1982, Jul-10, Volume: 285, Issue:6335

    Topics: Chronic Disease; Furosemide; Humans; Inappropriate ADH Syndrome; Sodium Chloride

1982
Combined treatment of severe hyponatremia due to inappropriate antidiuretic hormone secretion.
    Pediatrics, 1982, Volume: 69, Issue:5

    Topics: Child; Desoxycorticosterone; Drug Therapy, Combination; Female; Furosemide; Humans; Hyponatremia; In

1982
[Inappropriate anti-diuretic hormone secretion syndrome associated with acute pneumonia].
    Revista clinica espanola, 1982, Apr-30, Volume: 165, Issue:2

    Topics: Acute Disease; Aged; Furosemide; Humans; Inappropriate ADH Syndrome; Male; Pneumonia; Sodium Chlorid

1982
Furosemide in inappropriate secretion of antidiuretic hormone.
    The New England journal of medicine, 1981, Jun-11, Volume: 304, Issue:24

    Topics: Ethacrynic Acid; Furosemide; Humans; Inappropriate ADH Syndrome; Kidney Tubules

1981
Treatment of the syndrome of inappropriate secretion of antidiuretic hormone with furosemide.
    The New England journal of medicine, 1981, Feb-05, Volume: 304, Issue:6

    Topics: Aged; Body Weight; Furosemide; Humans; Inappropriate ADH Syndrome; Male

1981
Inappropriate antidiuretic hormone secretion.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Acute Disease; Butorphanol; Chronic Disease; Demeclocycline; Drinking Behavior; Furosemide; Humans;

1994
Diagnosis and treatment of hyponatraemia in SIAD.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:5

    Topics: Diuretics; Furosemide; Humans; Hyponatremia; Inappropriate ADH Syndrome; Saline Solution, Hypertonic

1997
Falciparum malaria: a case report of severe hyponatraemia.
    Annals of tropical medicine and parasitology, 2000, Volume: 94, Issue:2

    Topics: Adult; Animals; Antiemetics; Antimalarials; Diuretics; Fatal Outcome; Furosemide; Humans; Hyponatrem

2000
Long-term treatment of patients with inappropriate secretion of antidiuretic hormone by the vasopressin receptor antagonist conivaptan, urea, or furosemide.
    The American journal of medicine, 2001, Volume: 110, Issue:7

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Diuretics; Female; Furosemide; Humans; Inap

2001
[Acute symptomatic hyponatremia in a 70-year-old patient. Insufficient ADH secretion syndrome].
    Medizinische Klinik (Munich, Germany : 1983), 2002, May-15, Volume: 97, Issue:5

    Topics: Aged; Diagnosis, Differential; Furosemide; Hematoma, Subdural; Humans; Hyponatremia; Inappropriate A

2002
Antidiuretic hormone excess.
    The Journal of pediatrics, 1979, Volume: 94, Issue:4

    Topics: Blood; Demeclocycline; Furosemide; Humans; Hyponatremia; Inappropriate ADH Syndrome; Lithium; Osmola

1979
Hyponatremia in myxedema: a suggested therapeutic approach.
    Israel journal of medical sciences, 1979, Volume: 15, Issue:11

    Topics: Aged; Female; Furosemide; Humans; Hyponatremia; Inappropriate ADH Syndrome; Myxedema; Saline Solutio

1979
Use of furosemide in patients with syndrome of inappropriate antidiuretic hormone secretion.
    Radiology, 1992, Volume: 182, Issue:3

    Topics: Furosemide; Humans; Inappropriate ADH Syndrome

1992
Inappropriate secretion of antidiuretic hormone in Sheehan's syndrome: a rare cause of postpartum hyponatremia.
    American journal of obstetrics and gynecology, 1991, Volume: 165, Issue:5 Pt 1

    Topics: Adult; Estrogens; Female; Follicle Stimulating Hormone; Furosemide; Growth Hormone; Humans; Hydrocor

1991
Oliguria in patients with normal renal function.
    Anesthesiology, 1990, Volume: 72, Issue:4

    Topics: Anuria; Blood Volume; Diuresis; Furosemide; Humans; Inappropriate ADH Syndrome; Kidney; Oliguria; Os

1990
Cis-dichlorodiammineplatinum II-induced syndrome of inappropriate secretion of antidiuretic hormone.
    Cancer, 1988, Feb-01, Volume: 61, Issue:3

    Topics: Cisplatin; Furosemide; Glioblastoma; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Mental

1988
Chronic syndrome of inappropriate secretion of antidiuretic hormone in childhood.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:7

    Topics: Child, Preschool; Female; Furosemide; Glioma; Humans; Inappropriate ADH Syndrome; Infant, Newborn; M

1985
Role of diuretics, hormonal derangements, and clinical setting of hyponatremia in medical patients.
    Klinische Wochenschrift, 1988, Aug-01, Volume: 66, Issue:15

    Topics: Aldosterone; Arginine Vasopressin; Diuretics; Electrolytes; Epinephrine; Furosemide; Heart Failure;

1988
[Effect of sodium load and furosemide administration on the chronic type of the syndrome of inappropriate secretion of antidiuretic hormone].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1987, Volume: 76, Issue:6

    Topics: Administration, Oral; Chronic Disease; Furosemide; Humans; Inappropriate ADH Syndrome; Male; Middle

1987