furosemide has been researched along with Hypercapnia in 16 studies
Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aerosolized furosemide has been shown to relieve dyspnea; nevertheless, all published studies have shown great variability in response." | 9.27 | Aerosol furosemide for dyspnea: Controlled delivery does not improve effectiveness. ( Banzett, RB; Lansing, RW; Morélot-Panzini, C; O'Donnell, CR; Schwartzstein, RM, 2018) |
| "We herein report two cases in which add-on acetazolamide to furosemide was effective for diuretic-resistant volume overload and hypercapnia." | 8.12 | The Effect of Add-on Acetazolamide to Conventional Diuretics for Diuretic-resistant Edema Complicated with Hypercapnia: A Report of Two Cases. ( Hisamichi, M; Ichikawa, D; Inoue, T; Shibagaki, Y; Yazawa, M, 2022) |
| "Aerosolized furosemide has been shown to relieve dyspnea; nevertheless, all published studies have shown great variability in response." | 5.27 | Aerosol furosemide for dyspnea: Controlled delivery does not improve effectiveness. ( Banzett, RB; Lansing, RW; Morélot-Panzini, C; O'Donnell, CR; Schwartzstein, RM, 2018) |
| "We previously showed that inhaled furosemide improves experimentally induced dyspnea." | 5.10 | Effects of inhaled furosemide on CO(2) ventilatory responsiveness in humans. ( Ide, T; Minowa, Y; Nishino, T, 2002) |
| "We herein report two cases in which add-on acetazolamide to furosemide was effective for diuretic-resistant volume overload and hypercapnia." | 4.12 | The Effect of Add-on Acetazolamide to Conventional Diuretics for Diuretic-resistant Edema Complicated with Hypercapnia: A Report of Two Cases. ( Hisamichi, M; Ichikawa, D; Inoue, T; Shibagaki, Y; Yazawa, M, 2022) |
| " Hypovolemia was induced by administration of furosemide, the body temperature (Tb) was gradually elevated to 42 degrees C by body surface heating." | 3.74 | Effects of hypovolemia on hypercapnic ventilatory response in experimental hyperthermia. ( Brozmanova, A; Calkovska, A; Javorka, K; Javorka, M; Zila, I, 2007) |
| "Normocapnic and chronic hypercapnic COPD patients have the same ventilatory and cerebrovascular carbon dioxide responsiveness irrespective of induced metabolic state." | 1.31 | Effects of acetazolamide and furosemide on ventilation and cerebral blood volume in normocapnic and hypercapnic patients with COPD. ( Colier, WN; Folgering, H; Oeseburg, B; van de Ven, MJ; van der Sluijs, MC; Vis, P, 2002) |
| "We quantitatively analyzed the effect of long-term administration of oral furosemide on the PaCO2 - H+ relationship in patients with chronic hypercapnic respiratory failure." | 1.30 | Effect of chronic furosemide administration on acid-base balance in patients with chronic hypercapnic respiratory failure. ( Kondo, T; Kumagai, M; Miyairi, A; Oh-Hori, KI; Ohta, Y; Urano, T, 1998) |
| "In conclusion, only hypercapnia and respiratory acidosis combined with hypoxemia decreases the natriuretic and diuretic effect of furosemide." | 1.27 | Furosemide pharmacodynamics: effect of respiratory and acid-base disturbances. ( Babini, R; du Souich, P, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Inoue, T | 1 |
| Hisamichi, M | 1 |
| Ichikawa, D | 1 |
| Shibagaki, Y | 1 |
| Yazawa, M | 1 |
| Morélot-Panzini, C | 1 |
| O'Donnell, CR | 1 |
| Lansing, RW | 2 |
| Schwartzstein, RM | 2 |
| Banzett, RB | 2 |
| Windsor, R | 1 |
| Petchey, W | 1 |
| Minowa, Y | 1 |
| Ide, T | 1 |
| Nishino, T | 1 |
| Moosavi, SH | 1 |
| Binks, AP | 1 |
| Topulos, GP | 1 |
| Zila, I | 1 |
| Brozmanova, A | 1 |
| Javorka, M | 1 |
| Calkovska, A | 1 |
| Javorka, K | 1 |
| Gaida, A | 1 |
| Mazza, R | 1 |
| Tanigaki, T | 1 |
| Kondo, T | 2 |
| Hayashi, Y | 1 |
| Katoh, H | 1 |
| Kamio, K | 1 |
| Urano, T | 2 |
| Ohta, Y | 2 |
| Oh-Hori, KI | 1 |
| Kumagai, M | 1 |
| Miyairi, A | 1 |
| van de Ven, MJ | 1 |
| Colier, WN | 1 |
| van der Sluijs, MC | 1 |
| Oeseburg, B | 1 |
| Vis, P | 1 |
| Folgering, H | 1 |
| Ullrich, KJ | 1 |
| Rumrich, G | 1 |
| Baumann, K | 1 |
| Heinemann, HO | 1 |
| Babini, R | 1 |
| du Souich, P | 1 |
| Johnson, DC | 1 |
| Singer, S | 1 |
| Hoop, B | 1 |
| Kazemi, H | 1 |
| Penman, RW | 1 |
| Luke, RG | 1 |
| Jarboe, TM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Specificity of Dyspnoea Relief With Inhaled Furosemide[NCT02881866] | Phase 1 | 16 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| Brain During Effort : Effects of Hypoxia With Respiratory Patients[NCT02854280] | 33 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for furosemide and Hypercapnia
| Article | Year |
|---|---|
Aerosol furosemide for dyspnea: Controlled delivery does not improve effectiveness.
Topics: Administration, Inhalation; Aerosols; Cross-Over Studies; Double-Blind Method; Dyspnea; Female; Furo | 2018 |
Effects of inhaled furosemide on CO(2) ventilatory responsiveness in humans.
Topics: Administration, Inhalation; Adult; Carbon Dioxide; Chemoreceptor Cells; Cross-Over Studies; Diuretic | 2002 |
Effect of inhaled furosemide on air hunger induced in healthy humans.
Topics: Administration, Inhalation; Adolescent; Adult; Analysis of Variance; Cross-Over Studies; Double-Blin | 2007 |
13 other studies available for furosemide and Hypercapnia
| Article | Year |
|---|---|
The Effect of Add-on Acetazolamide to Conventional Diuretics for Diuretic-resistant Edema Complicated with Hypercapnia: A Report of Two Cases.
Topics: Acetazolamide; Diuretics; Edema; Female; Furosemide; Humans; Hypercapnia; Male | 2022 |
Metabolic alkalosis in a patient with dyspnoea.
Topics: Acidosis; Asthma; Diuretics; Dyspnea; Female; Furosemide; Humans; Hypercapnia; Middle Aged; Pneumoni | 2013 |
Effects of hypovolemia on hypercapnic ventilatory response in experimental hyperthermia.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Blood Volume; Body Temperature; Diuretics; Female; Feve | 2007 |
[Influence of a sulfonamide diuretic on the pO2 and on the acid-base equilibrium of chronic hypercapnic lung disease patients].
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Aged; Furosemide; Humans; Hypercapnia; Middle Aged; Ox | 1967 |
Rapid response to inhaled frusemide in severe acute asthma with hypercapnia.
Topics: Acute Disease; Administration, Inhalation; Asthma; Blood Gas Analysis; Diuretics; Dose-Response Rela | 1997 |
Effect of chronic furosemide administration on acid-base balance in patients with chronic hypercapnic respiratory failure.
Topics: Acid-Base Equilibrium; Aged; Blood Gas Analysis; Dose-Response Relationship, Drug; Drug Administrati | 1998 |
Effects of acetazolamide and furosemide on ventilation and cerebral blood volume in normocapnic and hypercapnic patients with COPD.
Topics: Acetazolamide; Administration, Oral; Alkalosis; Blood Volume; Carbon Dioxide; Cerebrovascular Circul | 2002 |
Renal proximal tubular buffer-(glycodiazine) transport. Inhomogeneity of local transport rate, dependence on sodium, effect of inhibitors and chronic adaptation.
Topics: Acid-Base Equilibrium; Animals; Biological Transport; Carbonic Anhydrase Inhibitors; Choline; Furose | 1975 |
Right-sided heart failure and the use of diuretics.
Topics: Adaptation, Physiological; Cardiac Output; Diuretics; Ethacrynic Acid; Furosemide; Heart Failure; Hu | 1978 |
Furosemide pharmacodynamics: effect of respiratory and acid-base disturbances.
Topics: Acidosis, Respiratory; Animals; Carbon Dioxide; Furosemide; Hypercapnia; Hypoxia; Kidney; Kinetics; | 1986 |
Chloride flux from blood to CSF: inhibition by furosemide and bumetanide.
Topics: Animals; Bumetanide; Chlorides; Chlorine; Diuretics; Dogs; Furosemide; Hypercapnia; Models, Biologic | 1987 |
The lazy respiratory center--or how to recognize a tired horse. Clinical conference in pulmonary disease from Northwestern University-McGaw Medical Center, Chicago.
Topics: Brain Diseases; Chemoreceptor Cells; Chronic Disease; Diagnosis, Differential; Diazepam; Digoxin; Fu | 1974 |
Respiratory effects of hypochloremic alkalosis and potassium depletion in the dog.
Topics: Acid-Base Equilibrium; Alkalosis; Animals; Bicarbonates; Carbon Dioxide; Chlorides; Desoxycorticoste | 1972 |