Page last updated: 2024-10-27

furosemide and Glioma

furosemide has been researched along with Glioma in 11 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"A perifusion technique for microscopy with computerized detection of early changes in cell morphology during continuous perifusion was used to show that the geometry of cultured glioma cells (MG-251) changes rapidly when they are exposed to estramustine phosphate (EMP)."7.69Computerized detection of morphological changes to glioma cells during estramustine and ion-channel blocker perifusion. ( Behnam-Motlagh, P; Engström, KG; Grankvist, K; Henriksson, R; Jonsson, O, 1997)
" Although bumetanide inhibition of Na-K-2Cl cotransport activity did not affect cell motility, treatment of glioma cells with furosemide to inhibit K-Cl cotransport activity prevented ~75% of wound closure in a reversible reaction."3.78High-grade glioma motility reduced by genetic knockdown of KCC3. ( Gagnon, KB, 2012)
"A perifusion technique for microscopy with computerized detection of early changes in cell morphology during continuous perifusion was used to show that the geometry of cultured glioma cells (MG-251) changes rapidly when they are exposed to estramustine phosphate (EMP)."3.69Computerized detection of morphological changes to glioma cells during estramustine and ion-channel blocker perifusion. ( Behnam-Motlagh, P; Engström, KG; Grankvist, K; Henriksson, R; Jonsson, O, 1997)
" We describe the clinical course and management of each patient, including the long-term use of furosemide taken orally once a day."1.27Chronic syndrome of inappropriate secretion of antidiuretic hormone in childhood. ( David, R; Fertig, A; Sklar, C, 1985)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gagnon, KB1
Johnson, JH1
Dunn, DP1
Rosenberg, RN1
Wolpaw, EW1
Martin, DL1
Pinegin, LE1
Dolzhenko, DA1
Meinig, G1
Sandström, PE1
Jonsson, O2
Grankvist, K2
Henriksson, R2
Behnam-Motlagh, P1
Engström, KG1
Sklar, C1
Fertig, A1
David, R1
Chassande, O1
Frelin, C1
Farahifar, D1
Jean, T1
Lazdunski, M1
Hayakawa, I1
Kim, CS1
Subedi, L1
Park, KJ1
Kim, SY1
Choi, SU1
Kim, KH1
Lee, KR1

Trials

1 trial available for furosemide and Glioma

ArticleYear
[Assessment of anti-oedematous therapy in brain tumour patients (author's transl)].
    Neurochirurgia, 1980, Volume: 23, Issue:6

    Topics: Brain Edema; Brain Neoplasms; Dexamethasone; Drug Therapy, Combination; Furosemide; Glioma; Humans;

1980

Other Studies

10 other studies available for furosemide and Glioma

ArticleYear
High-grade glioma motility reduced by genetic knockdown of KCC3.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 30, Issue:2

    Topics: Animals; Astrocytes; Cell Movement; Cells, Cultured; Furosemide; Gene Knockdown Techniques; Glioma;

2012
Furosemide-sensitive K+ channel in glioma cells but not neuroblastoma cells in culture.
    Biochemical and biophysical research communications, 1982, Nov-16, Volume: 109, Issue:1

    Topics: Animals; Biological Transport, Active; Cations, Monovalent; Cell Line; Furosemide; Glioma; Ion Chann

1982
Cl- transport in a glioma cell line: evidence for two transport mechanisms.
    Brain research, 1984, Apr-16, Volume: 297, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Astrocytes; Bicarbonates; Cell

1984
[Effect of furosemide on intracranial pressure in patients with intracranial hypertension].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:5

    Topics: Brain Diseases; Brain Neoplasms; Chlorides; Diuresis; Furosemide; Glioma; Humans; Intracranial Press

1983
Identification of potassium flux pathways and their role in the cytotoxicity of estramustine in human malignant glioma, prostatic carcinoma and pulmonary carcinoma cell lines.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:12

    Topics: Bumetanide; Cell Division; Estramustine; Furosemide; Glioma; Humans; Ion Transport; Lung Neoplasms;

1994
Computerized detection of morphological changes to glioma cells during estramustine and ion-channel blocker perifusion.
    British journal of cancer, 1997, Volume: 76, Issue:3

    Topics: Bumetanide; Cell Size; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estramustine; Furosemide

1997
Chronic syndrome of inappropriate secretion of antidiuretic hormone in childhood.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:7

    Topics: Child, Preschool; Female; Furosemide; Glioma; Humans; Inappropriate ADH Syndrome; Infant, Newborn; M

1985
The Na+/K+/Cl- cotransport in C6 glioma cells. Properties and role in volume regulation.
    European journal of biochemistry, 1988, Feb-01, Volume: 171, Issue:3

    Topics: Biological Transport; Bumetanide; Carrier Proteins; Cells, Cultured; Chlorides; Flow Cytometry; Furo

1988
[Clinical studies on a new intracranial pressure reducing agent].
    Zentralblatt fur Neurochirurgie, 1967, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Diseases; Brain Injuries; Brain Neoplasms; Craniopharyng

1967
Salicin derivatives from Salix glandulosa and their biological activities.
    Fitoterapia, 2015, Volume: 106

    Topics: Animals; Benzyl Alcohols; Cell Line, Tumor; Cell Survival; Glioma; Glucosides; Mice; Microglia; Mole

2015