furosemide has been researched along with Ductus Arteriosus, Patent in 43 studies
Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
Ductus Arteriosus, Patent: A congenital heart defect characterized by the persistent opening of fetal DUCTUS ARTERIOSUS that connects the PULMONARY ARTERY to the descending aorta (AORTA, DESCENDING) allowing unoxygenated blood to bypass the lung and flow to the PLACENTA. Normally, the ductus is closed shortly after birth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Twelve risk factors for dTSH were identified on univariate analysis: cesarean section, mechanical ventilation, patent ductus arteriosus (PDA), pneumothorax, and administration of cefotaxime, vancomycin, fluconazole, dopamine, ibuprofen, furosemide, insulin, and packed red blood cells." | 3.85 | Risk Factors for the Development of Delayed TSH Elevation in Neonatal Intensive Care Unit Newborns. ( Almashanu, S; Bier Palmon, R; Eventov-Friedman, S; Flidel-Rimon, O; Golan, A; Kats, N; Keidar, R; Marom, R; Troitzky, M; Zung, A, 2017) |
| " Four had severe hyaline membrane disease and one had chronic bronchopulmonary dysplasia; all received furosemide." | 3.66 | Urinary excretion of prostaglandin E following the administration of furosemide and indomethacin to sick low-birth-weight infants. ( Demers, LM; Friedman, Z; Maisels, MJ; Marks, KH; Uhrmann, S, 1978) |
| "Furosemide is known to increase renal prostaglandin synthesis." | 2.75 | Effect of furosemide on ductal closure and renal function in indomethacin-treated preterm infants during the early neonatal period. ( Byun, SY; Chang, JY; Chung, ML; Kim, EA; Kim, HY; Kim, KS; Lee, BS; Pi, SY, 2010) |
| "Pulmonary edema has been demonstrated in the early stages of respiratory distress syndrome in premature infants." | 2.65 | Early furosemide therapy in premature infants (less than or equal to 2000 gm) with respiratory distress syndrome: a randomized controlled trial. ( Leu, ST; Pildes, RS; Raval, D; Shibli, A; Yeh, TF, 1984) |
| "During the study, the incidence of patent ductus arteriosus was significantly higher (P less than 0." | 2.65 | Furosemide promotes patent ductus arteriosus in premature infants with the respiratory-distress syndrome. ( Green, TP; Johnson, DE; Lock, JE; Thompson, TR, 1983) |
| " Dosing regimens of frusemide, and acetaminophen, and the sizes of ductus arteriosus following treatment, were evaluated." | 1.62 | Intravenous frusemide does not interact pharmacodynamically with acetaminophen in critically ill preterm neonates with patent ductus arteriosus. ( Al Ansari, E; Al Jufairi, M; Al Madhoob, A; Al Marzooq, R; Sridharan, K, 2021) |
| "Furosemide was prescribed to 4055 (9%) infants." | 1.48 | Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight. ( Bell, N; Clark, RH; Crowell, A; Greenberg, RG; Harrison, L; Hornik, CP; Kumar, K; Laughon, M; Scales, G; Shaw, L; Smith, PB; Thompson, EJ, 2018) |
| "All VLBW infants examined for hearing impairment were included and data were retrieved retrospectively and analyzed for neonatal risk factors using logistic regression." | 1.46 | Prevalence and independent risk factors for hearing impairment among very low birth weight infants. ( Chiang, MC; Chu, SM; Fu, RH; Hsu, JF; Lien, R; Wang, CH; Yang, CY, 2017) |
| "Furosemide was also s." | 1.36 | In vivo dilatation of the ductus arteriosus induced by furosemide in the rat. ( Momma, K; Nakanishi, T; Toyoshima, K, 2010) |
| "Symptomatic patent ductus arteriosus (sPDA) may occur in up to 50% of very-low-birth-weight (VLBW, less than or equal to 1500 g) infants." | 1.28 | Symptomatic patent ductus arteriosus in very-low-birth-weight infants: 1987-1989. ( Mouzinho, AI; Risser, R; Rosenfeld, CR, 1991) |
| "Furosemide is a known stimulant of the renal release of prostaglandin E2, a potent dilator of the ductus arteriosus." | 1.26 | Furosemide use in premature infants and appearance of patent ductus arteriosus. ( Green, TP; Johnson, D; Lock, JE; Thompson, TR, 1981) |
| "An infant with Ebstein's malformation of the tricuspid valve and severe pulmonic stenosis underwent a 39-day course of prostaglandin E1 infusion, and a histologic study of the ductus arteriosus was undertaken after autopsy." | 1.26 | Prolonged prostaglandin E1 infusion: histologic effects on the patent ductus arteriosus. ( Abman, S; Aziz, KU; Bharati, S; Cole, RB; Lev, M, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (53.49) | 18.7374 |
| 1990's | 4 (9.30) | 18.2507 |
| 2000's | 3 (6.98) | 29.6817 |
| 2010's | 10 (23.26) | 24.3611 |
| 2020's | 3 (6.98) | 2.80 |
| Authors | Studies |
|---|---|
| Dudley, S | 1 |
| Sen, S | 1 |
| Hanson, A | 1 |
| El Khuffash, A | 1 |
| Levy, PT | 1 |
| Iacobelli, S | 1 |
| Lorrain, S | 1 |
| Gouyon, B | 1 |
| Gambacorta, S | 1 |
| Laforgia, N | 1 |
| Gouyon, JB | 1 |
| Bonsante, F | 1 |
| Sridharan, K | 1 |
| Al Madhoob, A | 1 |
| Al Jufairi, M | 1 |
| Al Ansari, E | 1 |
| Al Marzooq, R | 1 |
| Zung, A | 1 |
| Bier Palmon, R | 1 |
| Golan, A | 1 |
| Troitzky, M | 1 |
| Eventov-Friedman, S | 1 |
| Marom, R | 1 |
| Keidar, R | 1 |
| Kats, N | 1 |
| Almashanu, S | 1 |
| Flidel-Rimon, O | 1 |
| Thompson, EJ | 1 |
| Greenberg, RG | 1 |
| Kumar, K | 1 |
| Laughon, M | 1 |
| Smith, PB | 1 |
| Clark, RH | 1 |
| Crowell, A | 1 |
| Shaw, L | 1 |
| Harrison, L | 1 |
| Scales, G | 1 |
| Bell, N | 1 |
| Hornik, CP | 1 |
| Seaton, R | 1 |
| Williams, C | 1 |
| Peredo, J | 1 |
| Arcinue, R | 1 |
| Kantak, A | 1 |
| Elkhwad, M | 1 |
| Wang, CH | 1 |
| Yang, CY | 1 |
| Lien, R | 1 |
| Chu, SM | 1 |
| Hsu, JF | 1 |
| Fu, RH | 1 |
| Chiang, MC | 1 |
| Andriessen, P | 1 |
| Struis, NC | 1 |
| Niemarkt, H | 1 |
| Oetomo, SB | 1 |
| Tanke, RB | 1 |
| Van Overmeire, B | 1 |
| Toyoshima, K | 1 |
| Momma, K | 1 |
| Nakanishi, T | 1 |
| Lee, BS | 1 |
| Byun, SY | 1 |
| Chung, ML | 1 |
| Chang, JY | 1 |
| Kim, HY | 1 |
| Kim, EA | 1 |
| Kim, KS | 1 |
| Pi, SY | 1 |
| Segar, JL | 1 |
| Pacifici, GM | 1 |
| Caivano, D | 1 |
| Birettoni, F | 1 |
| Fruganti, A | 1 |
| Rishniw, M | 1 |
| Knafelz, P | 1 |
| Moïse, NS | 1 |
| Porciello, F | 1 |
| Green, TP | 3 |
| Thompson, TR | 3 |
| Johnson, DE | 2 |
| Lock, JE | 3 |
| Yee, WF | 1 |
| Cataletto, M | 1 |
| Scarpelli, EM | 1 |
| Yeh, TF | 3 |
| Shibli, A | 1 |
| Leu, ST | 1 |
| Raval, D | 1 |
| Pildes, RS | 3 |
| de Sarasqueta, P | 1 |
| Segura-Roldán, MA | 1 |
| Valls, M | 1 |
| Lozano-González, CH | 1 |
| Russo, EA | 1 |
| Yu, VY | 1 |
| Knight, DB | 1 |
| Obeyesekere, HI | 1 |
| Mitvalsky, J | 1 |
| Goldsmith, MA | 1 |
| Bhatia, SS | 1 |
| Kanto, WP | 1 |
| Kutner, MH | 1 |
| Rudman, D | 1 |
| Cohen, JI | 1 |
| Wilks, A | 2 |
| Singh, J | 1 |
| Betkerur, M | 1 |
| Lilien, L | 1 |
| Hufnagle, KG | 1 |
| Khan, SN | 1 |
| Penn, D | 1 |
| Cacciarelli, A | 1 |
| Williams, P | 1 |
| Jaso, E | 1 |
| Tejedor, JC | 1 |
| Quero, J | 1 |
| Pérez Rodríguez, J | 1 |
| Agustí, B | 1 |
| Castro, J | 1 |
| García Frías, E | 1 |
| Johnson, D | 1 |
| Cole, RB | 1 |
| Abman, S | 1 |
| Aziz, KU | 1 |
| Bharati, S | 1 |
| Lev, M | 1 |
| van den Anker, JN | 1 |
| Romagnoli, C | 1 |
| Zecca, E | 1 |
| Papacci, P | 1 |
| De Carolis, MP | 1 |
| Giannini, R | 1 |
| Gallini, F | 1 |
| Tortorolo, G | 1 |
| Brion, LP | 3 |
| Campbell, DE | 3 |
| Cotton, RB | 2 |
| Stahlman, MT | 2 |
| Kovar, I | 2 |
| Catterton, WZ | 2 |
| Friedman, Z | 1 |
| Demers, LM | 1 |
| Marks, KH | 1 |
| Uhrmann, S | 1 |
| Maisels, MJ | 1 |
| Bender, HW | 1 |
| Graham, TP | 1 |
| Hall, GS | 1 |
| Helmsworth, JA | 1 |
| Schreiber, JT | 1 |
| Rosenkrantz, JG | 1 |
| Martin, LW | 1 |
| Baylen, BG | 1 |
| Kaplan, S | 1 |
| Mouzinho, AI | 1 |
| Rosenfeld, CR | 1 |
| Risser, R | 1 |
| Aranda, JV | 1 |
| Chemtob, S | 1 |
| Laudignon, N | 1 |
| Sasyniuk, BI | 1 |
| Vargas-Origel, A | 1 |
| Cruz-Anguiano, V | 1 |
| López-Montaño, E | 1 |
| Luken, J | 1 |
| Robertson, NR | 1 |
| Richardson, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease[NCT01721655] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2012-10-31 | Recruiting | ||
| A Retrospective Chart Review Evaluating the Impact of Steroid, Diuretic, and Fluid Use Practice Trends in Extreme Premature Infants at Risk for Bronchopulmonary Dysplasia (BPD) at a Single Center Neonatal Intensive Care Unit[NCT04971694] | 175 participants (Anticipated) | Observational | 2021-09-08 | Recruiting | |||
| Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis[NCT02469597] | Phase 2 | 46 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02469597)
Timeframe: Participants will be followed for the duration of hospital stay up to 1 week
| Intervention | Days (Least Squares Mean) |
|---|---|
| Single Dose of Furosemide | 3.1 |
| Placebo | 3.0 |
(NCT02469597)
Timeframe: 2 hours after medication adminstration
| Intervention | Percentage change in oxygen saturation (Least Squares Mean) |
|---|---|
| Single Dose of Furosemide | -0.14 |
| Placebo | 0.2 |
(NCT02469597)
Timeframe: 4 hours after medication adminstration
| Intervention | Percentage change in oxygen saturation (Least Squares Mean) |
|---|---|
| Single Dose of Furosemide | -0.19 |
| Placebo | 0.29 |
(NCT02469597)
Timeframe: Within 72 hours of medication administration
| Intervention | participants (Number) |
|---|---|
| Single Dose of Furosemide | 0 |
| Placebo | 0 |
(NCT02469597)
Timeframe: 2 hours after medication adminstration
| Intervention | Percentage change in respiratory rate (Least Squares Mean) |
|---|---|
| Single Dose of Furosemide | -3.7 |
| Placebo | -1.7 |
(NCT02469597)
Timeframe: 4 hours after medication adminstration
| Intervention | Percentage change in respiratory rate (Least Squares Mean) |
|---|---|
| Single Dose of Furosemide | -2.8 |
| Placebo | -5.4 |
8 reviews available for furosemide and Ductus Arteriosus, Patent
| Article | Year |
|---|---|
The role of furosemide and fluid management for a hemodynamically significant patent ductus arteriosus in premature infants.
Topics: Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Pr | 2022 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants.
Topics: Acetazolamide; Bumetanide; Drug Therapy, Combination; Ductus Arteriosus, Patent; Extracorporeal Memb | 2012 |
Pharmacokinetics and renal function in preterm infants.
Topics: Betamethasone; Diuretics; Dopamine; Ductus Arteriosus, Patent; Furosemide; Gestational Age; Glomerul | 1996 |
Furosemide in indomethacin-treated infants--systematic review and meta-analysis.
Topics: Blood Urea Nitrogen; Body Water; Drug Therapy, Combination; Ductus Arteriosus, Patent; Furosemide; G | 1999 |
Furosemide for symptomatic patent ductus arteriosus in indomethacin-treated infants.
Topics: Cyclooxygenase Inhibitors; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; I | 2000 |
Furosemide for symptomatic patent ductus arteriosus in indomethacin-treated infants.
Topics: Cyclooxygenase Inhibitors; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; I | 2001 |
Furosemide and vitamin E. Two problem drugs in neonatology.
Topics: Acid-Base Imbalance; Anemia; Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Diuresis; Ductus Arter | 1986 |
7 trials available for furosemide and Ductus Arteriosus, Patent
| Article | Year |
|---|---|
Effect of furosemide on ductal closure and renal function in indomethacin-treated preterm infants during the early neonatal period.
Topics: Acute Kidney Injury; Creatinine; Cyclooxygenase Inhibitors; Drug Interactions; Ductus Arteriosus, Pa | 2010 |
Diuresis and pulmonary function in premature infants with respiratory distress syndrome.
Topics: Chlorothiazide; Clinical Trials as Topic; Diuresis; Ductus Arteriosus, Patent; Furosemide; Humans; I | 1983 |
Early furosemide therapy in premature infants (less than or equal to 2000 gm) with respiratory distress syndrome: a randomized controlled trial.
Topics: Bronchopulmonary Dysplasia; Clinical Trials as Topic; Ductus Arteriosus, Patent; Furosemide; Humans; | 1984 |
Furosemide promotes patent ductus arteriosus in premature infants with the respiratory-distress syndrome.
Topics: Chlorothiazide; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newborn; Kidney; Prostaglandi | 1983 |
Furosemide prevents the renal side effects of indomethacin therapy in premature infants with patent ductus arteriosus.
Topics: Drug Therapy, Combination; Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; Infant, Newb | 1982 |
Furosemide does not prevent indomethacin-induced renal side effects in preterm infants.
Topics: Body Weight; Cyclooxygenase Inhibitors; Diuretics; Ductus Arteriosus, Patent; Female; Furosemide; Ge | 1997 |
Randomized trial of early closure of symptomatic patent ductus arteriosus in small preterm infants.
Topics: Digoxin; Ductus Arteriosus, Patent; Economics, Medical; Furosemide; Humans; Infant, Newborn; Infant, | 1978 |
28 other studies available for furosemide and Ductus Arteriosus, Patent
| Article | Year |
|---|---|
Drug exposure for PDA closure in France: a prospective, cohort-based, analysis.
Topics: Acetaminophen; Administration, Oral; Drug Resistance; Drug Utilization; Ductus Arteriosus, Patent; F | 2020 |
Intravenous frusemide does not interact pharmacodynamically with acetaminophen in critically ill preterm neonates with patent ductus arteriosus.
Topics: Acetaminophen; Administration, Intravenous; Critical Illness; Ductus Arteriosus, Patent; Female; Fur | 2021 |
Risk Factors for the Development of Delayed TSH Elevation in Neonatal Intensive Care Unit Newborns.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Cefotaxime; Cesar | 2017 |
Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight.
Topics: Ductus Arteriosus, Patent; Female; Furosemide; Hospitalization; Humans; Infant, Newborn; Infant, Pre | 2018 |
Comparative case studies: PDAs treated with medication, surgical ligation, and transcatheter device closure.
Topics: Cardiac Catheterization; Cardiac Surgical Procedures; Cyclooxygenase Inhibitors; Diuretics; Ductus A | 2019 |
Acute kidney injury in ELBW infants (< 750 grams) and its associated risk factors.
Topics: Abruptio Placentae; Acute Kidney Injury; Adult; Amphotericin B; Anti-Bacterial Agents; Case-Control | 2015 |
Prevalence and independent risk factors for hearing impairment among very low birth weight infants.
Topics: Anti-Bacterial Agents; Craniofacial Abnormalities; Diuretics; Ductus Arteriosus, Patent; Evoked Pote | 2017 |
Furosemide in preterm infants treated with indomethacin for patent ductus arteriosus.
Topics: Cohort Studies; Creatinine; Cyclooxygenase Inhibitors; Diuretics; Ductus Arteriosus, Patent; Female; | 2009 |
In vivo dilatation of the ductus arteriosus induced by furosemide in the rat.
Topics: Animals; Animals, Newborn; Cesarean Section; Cyclooxygenase Inhibitors; Dilatation, Pathologic; Dise | 2010 |
Transthoracic echocardiographically-guided interventional cardiac procedures in the dog.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Balloon Valvuloplasty; Benzazepines; Cardiotonic | 2012 |
New concepts in neonatal respiratory distress syndrome.
Topics: Ductus Arteriosus, Patent; Female; Fetal Organ Maturity; Fluid Therapy; Furosemide; Humans; Infant, | 1984 |
[Echocardiographic study of the persistence of the ductus arteriosus in premature newborn infants].
Topics: Digoxin; Ductus Arteriosus, Patent; Echocardiography; Furosemide; Humans; Infant, Newborn; Infant, P | 1984 |
Iatrogenic metabolic alkalosis with respiratory alkalosis in a dog with patent ductus arteriosus.
Topics: Alkalosis; Alkalosis, Respiratory; Animals; Dog Diseases; Dogs; Ductus Arteriosus, Patent; Female; F | 1983 |
The management of patient ductus arteriosus in very low birthweight infants.
Topics: Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; Infant; Infant, Low Birth Weight; Infan | 1983 |
Gluconate calcium therapy and neonatal hypercalciuria.
Topics: Calcium; Calcium Gluconate; Creatinine; Ductus Arteriosus, Patent; Furosemide; Gluconates; Humans; I | 1981 |
Promotion of patent ductus arteriosus by furosemide.
Topics: Ductus Arteriosus, Patent; Female; Fetus; Furosemide; Humans; Infant, Newborn; Maternal-Fetal Exchan | 1983 |
Renal calcifications: a complication of long-term furosemide therapy in preterm infants.
Topics: Ductus Arteriosus, Patent; Furosemide; Heart Failure; Humans; Infant; Infant, Newborn; Infant, Prema | 1982 |
[Treatment of patent ductus arteriosus in preterm infants].
Topics: Digoxin; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Indomethacin; Infant, Low Birth Weig | 1982 |
Furosemide use in premature infants and appearance of patent ductus arteriosus.
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Fluid Therapy; Furosemide; Humans; Infant, Newborn; Re | 1981 |
Prolonged prostaglandin E1 infusion: histologic effects on the patent ductus arteriosus.
Topics: Cardiac Catheterization; Digoxin; Ductus Arteriosus; Ductus Arteriosus, Patent; Ebstein Anomaly; Fem | 1981 |
Medical management of small preterm infants with symptomatic patent ductus arteriosus.
Topics: Blood Transfusion; Digoxin; Ductus Arteriosus, Patent; Furosemide; Heart Failure; Hematocrit; Humans | 1978 |
Urinary excretion of prostaglandin E following the administration of furosemide and indomethacin to sick low-birth-weight infants.
Topics: Calcium; Drug Antagonism; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Hyaline Membrane Di | 1978 |
Premature infants with patent ductus arteriosus and respiratory distress: selection for ductal ligation.
Topics: Digitalis Glycosides; Ductus Arteriosus, Patent; Echocardiography; Female; Furosemide; Heart Failure | 1976 |
Symptomatic patent ductus arteriosus in very-low-birth-weight infants: 1987-1989.
Topics: Analysis of Variance; Cardiac Surgical Procedures; Colloids; Ductus Arteriosus, Patent; Female; Flui | 1991 |
[Indomethacin and furosemide in closure of ductus arteriosus].
Topics: Drug Evaluation; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Indomethacin; Infant, Newbor | 1986 |
Indomethacin therapy in premature infants with patent ductus arteriosus and oliguria.
Topics: Anuria; Drug Therapy, Combination; Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; Infa | 1986 |
Prolonged continuous positive airways pressure for pulmonary oedema due to persistent ductus arteriosus in the newborn.
Topics: Carbon Dioxide; Cardiac Catheterization; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Infa | 1974 |
Frusemide in heart failure of infancy.
Topics: Administration, Oral; Aortic Coarctation; Body Weight; Chlorides; Ductus Arteriosus, Patent; Female; | 1971 |