furosemide and Diabetes Insipidus studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Diabetes Insipidus: A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.

Research Excerpts

Excerpt	Relevance	Reference
" The present study examines the effect of acetazolamide, hydrochlorothiazide, furosemide, and amiloride on the distal reabsorption of lithium in conscious rats with hereditary diabetes insipidus fed standard diets with medium (300 mmol Na/kg) and low (5 mmol Na/kg) sodium contents, respectively."	3.67	Acute effects of various diuretics on lithium clearance. Studies in rats on medium and low sodium diet. ( Leyssac, PP; Thomsen, K, 1986)
"Brattleboro rats homozygous for hypothalamic hereditary diabetes insipidus (DI rats) were used to investigate the following questions: a) Do exogenous and endogenous angiotensin II (AII) have an antidiuretic effect in diabetes insipidus? b) Does AII mediate the antidiuresis induced by furosemide? The following results were obtained: 1."	3.66	Inhibition of the renin-angiotensin-system in Brattleboro rats with hereditary hypothalamic diabetes insipidus. ( Dietz, R; Mann, JF; Rascher, W; Schömig, A, 1978)
"The effect of furanthril after an acute (24 hours) and chronic administration (7 days), and the effect of 7-days sodium loading was followed on control Long Evans (LE) and Brattleboro rats with inherited hypothalamic diabetes insipidus (DI)."	1.27	Hormonal regulation of sodium-fluid balance and some hemodynamic parameters in the rat. II. The effect of sodium depletion and sodium loading on rats with inherited diabetes insipidus (Brattleboro strain). ( Somova, L, 1987)
"Patients suffering from liver cirrhosis with ascites showed significantly higher arginine vasopressin levels, approaching normal values, when ascites was under control."	1.26	Improved method and its clinical application of a radioimmunoassay of arginine vasopressin in human serum. ( Franz, HE; Maier, V; Wagner, H, 1977)

Timeframe	Studies, this research(%)	All Research%
pre-1990	46 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Torretti, J	2
Zanzi, I	2
Fraser, AG	1
Cowie, JF	1
Lambie, AT	1
Robson, JS	1
Fossati, C	1
Stamoutsos, BA	1
Carpenter, RG	1
Grossman, SP	1
Moses, AM	1
Notman, DD	1
Mann, JF	1
Rascher, W	1
Schömig, A	1
Dietz, R	1
De Groot, CA	1
Tijssen, AM	1
Wagner, H	1
Maier, V	1
Franz, HE	1
Werning, C	1
Peter, ST	1
Möhring, J	1
Krumlovsky, FA	1
del Greco, F	1
Jaisser, F	1
Blot-Chabaud, M	1
Pradelles, P	1
Bonvalet, JP	1
Farman, N	1
Somova, L	1
Thomsen, K	1
Leyssac, PP	1
Brown, JJ	2
Lever, AF	2
Robertson, JI	2
Reimold, EW	1
Senft, G	1
Munske, K	1
Schultz, G	1
Hoffmann, M	1
Chinn, RH	1
Dusterdieck, GO	1
Salvetti, A	1
Arzilli, P	1
Russo, R	1
Hepp, KD	1
Loew, D	1
Meng, K	1
Radò, JP	9
Juhos, E	1
Szende, L	5
Marosi, J	3
Takò, J	8
Salamon, F	1
Frazier, HS	1
Yager, H	1
Martinez-Maldonado, M	1
Eknoyan, G	1
Suki, WN	1
Irtel von Brenndorff, A	1
Hagge, W	1
Szabó, T	2
Dévényi, I	1
Hutás, I	1
Gartner, P	1
Gergely, R	1
Kirkendall, WM	1
Stein, JH	1
Szám, I	2
Borbély, L	4
Szigeti, L	2
Anderton, JL	1
Kincaid-Smith, P	1
Harrington, AR	1
Tozyo, S	1
Ueno, M	1
Ullrich, KJ	1
Baumann, K	1
Loeschke, K	1
Rumrich, G	1
Stolte, H	1
Relkin, R	1
Bános, C	3
Radó, J	1
Mazaré, Y	1
Micoud, M	1
Cordonnier, J	1
Soto, I	1
Onen, K	1
Obek, A	1
Branciari, C	1
Lauro, G	1
Menghini, G	1
Baba, WI	1
Lant, AF	1
Wilson, GM	1
Plöchl, E	1
Stur, O	1

Article	Year
[Diuretics. II]. La Clinica terapeutica, 1981, Nov-30, Volume: 99, Issue:4 Topics: Acetazolamide; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antihypertensive Agents; Cardiac Glyc	1981
Diabetes insipidus and syndrome of inappropriate antidiuretic hormone secretion (SIADH). Advances in internal medicine, 1982, Volume: 27 Topics: Anti-Inflammatory Agents; Chlorpropamide; Diabetes Insipidus; Female; Furosemide; Humans; Inappropri	1982
The clinical use of diuretics. 2. The New England journal of medicine, 1973, Mar-01, Volume: 288, Issue:9 Topics: Acute Kidney Injury; Diabetes Insipidus; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypertensio	1973
Diuretics in nonedematous states. Physiological basis for the clinical use. Archives of internal medicine, 1973, Volume: 131, Issue:6 Topics: Acidosis, Renal Tubular; Barbiturates; Calcium; Chlorothiazide; Cystinuria; Diabetes Insipidus; Diab	1973
Clinical pharmacology of furosemide and ethacrynic acid. The American journal of cardiology, 1968, Volume: 22, Issue:2 Topics: Anuria; Diabetes Insipidus; Edema; Ethacrynic Acid; Furosemide; Heart Failure; Hemodynamics; Humans;	1968
Diuretics. II. Clinical considerations. Drugs, 1971, Volume: 1, Issue:2 Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I	1971

Article	Year
Intravenous furosemide in diabetes insipidus. Metabolism: clinical and experimental, 1967, Volume: 16, Issue:6 Topics: Creatine; Diabetes Insipidus; Diuresis; Female; Furosemide; Humans; Kidney Tubules; Male; Natriuresi	1967
The effects of furosemide on the osmolality of the urine and the composition of renal tissue. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:3 Topics: Adult; Animals; Biological Transport; Cell Membrane Permeability; Creatinine; Dehydration; Diabetes	1967
Role of angiotensin-II in the polydipsia of diabetes insipidus in the Brattleboro rat. Physiology & behavior, 1981, Volume: 26, Issue:4 Topics: Angiotensin II; Animals; Captopril; Diabetes Insipidus; Drinking; Furosemide; Male; Quinine; Rats; R	1981
Inhibition of the renin-angiotensin-system in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Klinische Wochenschrift, 1978, Volume: 56 Suppl 1 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Insipidus; Diuresis; Fur	1978
The effects of long-term oral treatment with chlorothiazide or furosemide on hereditary diabetes insipidus in rats. Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 237, Issue:1 Topics: Animals; Chlorothiazide; Diabetes Insipidus; Diuresis; Electrolytes; Female; Furosemide; Natriuresis	1979
Improved method and its clinical application of a radioimmunoassay of arginine vasopressin in human serum. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1977, Volume: 9, Issue:3 Topics: Arginine Vasopressin; Diabetes Insipidus; Evaluation Studies as Topic; Furosemide; Humans; Liver Cir	1977
[The therapy of edematous diseases]. Fortschritte der Medizin, 1977, Aug-18, Volume: 95, Issue:31 Topics: Antihypertensive Agents; Bed Rest; Diabetes Insipidus; Diuretics; Diuretics, Osmotic; Edema; Ethacry	1977
[Dynamics of epithelioid cells in juxtaglomerular apparatus]. Verhandlungen der Anatomischen Gesellschaft, 1976, Issue:70 Pt 1 Topics: Diabetes Insipidus; Epithelial Cells; Epithelium; Furosemide; Juxtaglomerular Apparatus; Water Depri	1976
Diuretic agents. Mechanisms of action and clinical uses. Postgraduate medicine, 1976, Volume: 59, Issue:4 Topics: Acute Kidney Injury; Benzothiadiazines; Carbonic Anhydrase Inhibitors; Diabetes Insipidus; Diuretics	1976
Antidiuretic hormone reduces the high PGE2 synthesis in papillary collecting duct of DI rats. Pflugers Archiv : European journal of physiology, 1989, Volume: 414, Issue:4 Topics: Animals; Deamino Arginine Vasopressin; Diabetes Insipidus; Dinoprostone; Diuresis; Female; Furosemid	1989
Hormonal regulation of sodium-fluid balance and some hemodynamic parameters in the rat. II. The effect of sodium depletion and sodium loading on rats with inherited diabetes insipidus (Brattleboro strain). Acta physiologica et pharmacologica Bulgarica, 1987, Volume: 13, Issue:3 Topics: Animals; Benzothiadiazines; Diabetes Insipidus; Diuretics; Furosemide; Male; Prostaglandins; Rats; R	1987
Acute effects of various diuretics on lithium clearance. Studies in rats on medium and low sodium diet. Renal physiology, 1986, Volume: 9, Issue:1-2 Topics: Acetazolamide; Amiloride; Animals; Diabetes Insipidus; Diet, Sodium-Restricted; Diuretics; Furosemid	1986
Renin in diabetes insipidus. Lancet (London, England), 1965, Dec-25, Volume: 2, Issue:7426 Topics: Angiotensin II; Diabetes Insipidus; Diuresis; Furosemide; Humans; Infusions, Parenteral; Renin; Spir	1965
[Angiotensin and saluretics in nephrogenic diabetes insipidus of early infancy]. Zeitschrift fur Kinderheilkunde, 1967, Volume: 101, Issue:1 Topics: Angiotensin II; Body Temperature; Chlorthalidone; Diabetes Insipidus; Electrolytes; Female; Furosemi	1967
[Influence of hydrochlorothiazide and other sulfamoyl diuretics on the activity of 3',5'-AMP phosphodiesterase in rat kidney]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:4 Topics: Adenine Nucleotides; Animals; Cyclic AMP; Diabetes Insipidus; Furosemide; Hydrochlorothiazide; Kidne	1968
Plasma angiotension II concentrations and antidiuresis in diabetes insipidus. Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:10 Topics: Angiotensin II; Diabetes Insipidus; Diuresis; Furosemide; Humans; Radioimmunoassay; Urine	1971
[On the antidiuretic action of angiotensin II and of furosemide in a case of renal diabetes insipidus]. Minerva pediatrica, 1973, Aug-14, Volume: 25, Issue:27 Topics: Angiotensin II; Diabetes Insipidus; Diuresis; Furosemide; Humans; Water-Electrolyte Balance	1973
[Letter: Effect of diuretics in diabetes insipidus]. Medizinische Klinik, 1974, Sep-06, Volume: 69, Issue:36 Topics: Angiotensin II; Benzothiadiazines; Diabetes Insipidus; Diuresis; Diuretics; Ethacrynic Acid; Furosem	1974
[Acute renal failure after scalding of the rat (author's transl)]. Langenbecks Archiv fur Chirurgie, 1974, Volume: 335, Issue:4 Topics: Acute Kidney Injury; Aldosterone; Animals; Anuria; Burns; Diabetes Insipidus; Disease Models, Animal	1974
Acute renal effects of high doses of furosemide administered intravenously in patients with advanced chronic renal insufficiency. Journal of medicine, 1973, Volume: 4, Issue:4 Topics: Acidosis, Renal Tubular; Blood; Creatinine; Dehydration; Diabetes Insipidus; Electrolytes; Furosemid	1973
[Furosemide therapy of diabetes insipidus renalis in identical twins]. Monatsschrift fur Kinderheilkunde, 1973, Volume: 121, Issue:7 Topics: Diabetes Insipidus; Diseases in Twins; Furosemide; Humans; Hypernatremia; Infant	1973
Excessive decrease in free water clearance induced by furosemide and ethacrynic acid in nephrogenic diabetes insipidus associated with renal tubular acidosis. Endokrinologie, 1973, Volume: 61, Issue:3 Topics: Acidosis, Renal Tubular; Adult; Chlorpropamide; Diabetes Insipidus; Ethacrynic Acid; Female; Furosem	1973
Hyponatremia due to sodium depletion in the absence of vasopressin. The American journal of physiology, 1972, Volume: 222, Issue:3 Topics: Animals; Body Weight; Depression, Chemical; Diabetes Insipidus; Diet; Feeding Behavior; Female; Furo	1972
[Use of diuretics and anti-diuretics]. Horumon to rinsho. Clinical endocrinology, 1971, Volume: 19, Issue:4 Topics: Adult; Chlorpropamide; Diabetes Insipidus; Diuretics; Female; Furosemide; Humans; Male; Nephrotic Sy	1971
Micropuncture experiments with saluretic sulfonamides. Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2 Topics: Animals; Chlorthalidone; Diabetes Insipidus; Furosemide; Hypotonic Solutions; Kidney Tubules; Natriu	1966
Inherited forms of diabetes insipidus and diagnostic drug applications. Annals of the New York Academy of Sciences, 1968, Jul-31, Volume: 151, Issue:2 Topics: Blood Volume; Cell Membrane Permeability; Chlorothiazide; Chlorpropamide; Diabetes Insipidus; Diabet	1968
Diuretic and antidiuretic effects of furosemide before and during the early period of pitressin therapy in diabetes insipidus. Endokrinologie, 1969, Volume: 54, Issue:1 Topics: Diabetes Insipidus; Diuresis; Female; Furosemide; Glomerular Filtration Rate; Humans; Hypertonic Sol	1969
[Clinical and pharmacologic studies in diabetes insipidus complicated by diabetes mellitus]. Orvosi hetilap, 1970, Feb-22, Volume: 111, Issue:8 Topics: Chlorpropamide; Diabetes Complications; Diabetes Insipidus; Diuresis; Furosemide; Humans; Male; Midd	1970
Concentrating power of the kidney after five years of pitressin-tannate therapy in a patient with diabetes insipidus untreated for 13 years. (Investigations during intravenous administration of hypertonic sodium chloride, lysine-vasopressin, clopamide and Endokrinologie, 1970, Volume: 55, Issue:5 Topics: Clopamide; Diabetes Insipidus; Diuresis; Female; Furosemide; Humans; Hypertonic Solutions; Kidney Co	1970
Investigation of the antidiuretic effect of high doses of intravenous chlorpropamide during excessive solute excretion induced by the combination of furosemide and clopamide in patients with diabetes insipidus. Endokrinologie, 1970, Volume: 56, Issue:2 Topics: Amides; Chlorpropamide; Clopamide; Diabetes Insipidus; Diuresis; Diuretics; Drug Synergism; Furosemi	1970
[Study on furosemide and its special application to the study of the diagnosis of diabetes insipidus]. Semaine therapeutique, 1967, Volume: 43, Issue:2 Topics: Diabetes Insipidus; Furosemide; Humans	1967
[Mechanism of the antidiuretic effect of furosemide in diabetes insipidus]. Revista medica de Chile, 1967, Volume: 95, Issue:11 Topics: Diabetes Insipidus; Female; Furosemide; Humans; Male	1967
Investigation of diuretic and antidiuretic properties of furosemide in diabetes insipidus. Endokrinologie, 1968, Volume: 53, Issue:3 Topics: Depression, Chemical; Diabetes Insipidus; Diuresis; Furosemide; Glomerular Filtration Rate; Humans;	1968
[A clinical study with 4-chloro-N-(furylmethyl) 5-sulfamoyl-anthranilic acid (Lasix)]. Tip Fakultesi mecmuasi, 1968, Volume: 31, Issue:2 Topics: Diabetes Insipidus; Diuresis; Furosemide; Glomerular Filtration Rate; Humans; Injections, Intravenou	1968
Use of hypertonic saline, clopamide and furosemide for evaluation of the concentrating defect in pitressin-treated diabetes insipidus. Medicina experimentalis : International journal of experimental medicine, 1968, Volume: 18, Issue:3 Topics: Amides; Clopamide; Diabetes Insipidus; Diuretics; Female; Furosemide; Humans; Hypertonic Solutions;	1968
Renographic studies during furosemide diuresis in partial ureteral obstruction. Radiologia clinica et biologica, 1969, Volume: 38, Issue:2 Topics: Diabetes Insipidus; Diagnosis, Differential; Diuresis; Furosemide; Humans; Iodine Isotopes; Kidney F	1969
[Clinical observations on the efficacy of a new diuretic: furosemide]. Gazzetta internazionale di medicina e chirurgia, 1965, Jul-31, Volume: 69, Issue:14 Topics: Adult; Aged; Ascites; Diabetes Insipidus; Diuretics; Furosemide; Heart Failure; Humans; Liver Cirrho	1965
The action of oral diuretics in diabetes insipidus. Proceedings of the Royal Society of Medicine, 1965, Volume: 58, Issue:11 Part 1 Topics: Adult; Diabetes Insipidus; Diuretics; Female; Furosemide; Humans; Hydroflumethiazide; Middle Aged; S	1965
[Sweat studies in renal diabetes insipidus during treatment with saluretics]. Helvetica paediatrica acta, 1965, Volume: 20, Issue:4 Topics: Chlorides; Chlorthalidone; Diabetes Insipidus; Diuretics; Furosemide; Humans; Infant, Newborn; Infan	1965

furosemide and Diabetes Insipidus

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