Page last updated: 2024-10-27

furosemide and Diabetes, Phosphate

furosemide has been researched along with Diabetes, Phosphate in 1 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alon, US1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention of Post-Cardiac Surgery Vitamin D Deficiency in Children With Congenital Heart Disease: A Pilot Dose Evaluation Randomized Controlled Trial[NCT01838447]Phase 246 participants (Actual)Interventional2013-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Blood 25 Hydroxyvitamin D (25OHD) Concentrations

Blood 25OHD will be measured to determine vitamin D deficiency, with a concentration below 50 nmol/L used to define deficiency. A PICU admission blood sample could not be obtained for one patient in the Usual Care Group and one patient in the High Dose Group, thus the total number analyzed differs from the full sample size. (NCT01838447)
Timeframe: 1 day (On admission to the pediatric intensive care unit (PICU) following CHD surgery)

Interventionnmol/L (Mean)
Usual Care Group34.8
High Dose Group52.0

Number of Participants With Hypercalcemia as a Vitamin D Related Adverse Event

Hypercalcemia will be defined as an ionized calcium level above 1.40 mmol/L; or above 1.45 mmol/L for children under 8 weeks. Hypercalcemia will be evaluated in blood collected immediately before CHD surgery and throughout the post-operative course (measurements are standard of care). (NCT01838447)
Timeframe: Immediately before surgery, on admission to the PICU following CHD surgery, and on post-operative days 1,3,5 & 10

InterventionNo. participants with hypercalcemia (Number)
Usual Care Group0
High Dose Group0

Post-operative PICU Catecholamine Requirements

Primarily, post-operative catecholamine requirements during the PICU admission will be evaluated as a dichotomous variable (yes/no). If a difference is noted in the primary analysis, inotrope requirements will be determined using the inotrope score, evaluated as the maximum score and in a time to event approach (off all inotropes, score of zero) (NCT01838447)
Timeframe: At any point between PICU admission and discharge, an average length of 5-7 days and not longer than 60 days

InterventionParticipants (Count of Participants)
Usual Care Group15
High Dose Group11

Number of Participants With Hypercalciuria

Hypercalciuria will be identified using calcium:creatinine ratios defined using age-specific norms and thresholds. (NCT01838447)
Timeframe: Immediately before surgery, on admission to the PICU following CHD surgery, and on the first post-operative day

,
InterventionParticipants (Count of Participants)
EnrolmentIntra-operativePost-Operative Day 1
High Dose Group041
Usual Care Group132

Reviews

1 review available for furosemide and Diabetes, Phosphate

ArticleYear
Nephrocalcinosis.
    Current opinion in pediatrics, 1997, Volume: 9, Issue:2

    Topics: Furosemide; Humans; Hypophosphatemia, Familial; Infant; Nephrocalcinosis

1997