furosemide has been researched along with Deficiency, Thiamine in 19 studies
Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have previously found thiamine (vitamin B1) deficiency in patients with congestive heart failure (CHF) who had received long-term furosemide therapy." | 9.08 | Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy. ( Almog, S; Ezra, D; Halkin, H; Motro, M; Peleg, E; Rosenthal, T; Seligmann, H; Shefi, M; Shimon, I; Vered, Z, 1995) |
| " Most studies assessing body thiamine status have reported variable degrees of thiamine deficiency in patients with heart failure, particularly those treated chronically with high doses of furosemide." | 8.93 | Does Long-Term Furosemide Therapy Cause Thiamine Deficiency in Patients with Heart Failure? A Focused Review. ( Alpert, MA; Balla, S; Katta, N, 2016) |
| "The prevalence of thiamine deficiency in heart failure (HF) patients has been reported to be as high as 50% in outpatient settings and has been found to be as high as 96% in the inpatient setting." | 7.83 | Prevalence of thiamine deficiency in a stable heart failure outpatient cohort on standard loop diuretic therapy. ( Miller, WL; Teigen, LM; Twernbold, DD, 2016) |
| "To assess the presence of thiamine deficiency in congestive heart failure patients receiving furosemide therapy." | 7.72 | Thiamine deficiency in congestive heart failure patients receiving long term furosemide therapy. ( Almalki, Y; Donnelly, J; Healey, J; Smith, S; Vaillancourt, R; Zenuk, C, 2003) |
| "To test the hypothesis that long-term furosemide therapy in patients with congestive heart failure (CHF) is associated with clinically significant thiamine deficiency via urinary loss." | 7.68 | Thiamine deficiency in patients with congestive heart failure receiving long-term furosemide therapy: a pilot study. ( Ezra, D; Halkin, H; Kaufmann, N; Motro, M; Rauchfleisch, S; Seligmann, H; Vered, Z, 1991) |
| "Thiamine levels were determined using the erythrocyte transketolase activity." | 6.73 | Influence of spironolactone therapy on thiamine blood levels in patients with heart failure. ( Albanesi Filho, FM; de Albuquerque, DC; Rocha, RM; Silva, GV; Tura, BR, 2008) |
| " Thus, it is assumed that long-term administration of furosemide could induce a thiamine deficiency." | 5.26 | Furosemide-induced thiamine deficiency. ( Itokawa, Y; Kawai, C; Yui, Y, 1980) |
| "We have previously found thiamine (vitamin B1) deficiency in patients with congestive heart failure (CHF) who had received long-term furosemide therapy." | 5.08 | Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy. ( Almog, S; Ezra, D; Halkin, H; Motro, M; Peleg, E; Rosenthal, T; Seligmann, H; Shefi, M; Shimon, I; Vered, Z, 1995) |
| " Most studies assessing body thiamine status have reported variable degrees of thiamine deficiency in patients with heart failure, particularly those treated chronically with high doses of furosemide." | 4.93 | Does Long-Term Furosemide Therapy Cause Thiamine Deficiency in Patients with Heart Failure? A Focused Review. ( Alpert, MA; Balla, S; Katta, N, 2016) |
| "The prevalence of thiamine deficiency in heart failure (HF) patients has been reported to be as high as 50% in outpatient settings and has been found to be as high as 96% in the inpatient setting." | 3.83 | Prevalence of thiamine deficiency in a stable heart failure outpatient cohort on standard loop diuretic therapy. ( Miller, WL; Teigen, LM; Twernbold, DD, 2016) |
| "Chronic administration of furosemide may induce thiamine deficiency and cause or aggravate myocardial dysfunction." | 3.74 | Cardiac alterations in furosemide-treated thiamine-deprived rats. ( Cunha Bastos, J; Cunha Bastos, VL; da Cunha, S; Mandarim-de-Lacerda, CA; Salles, JB; Silva, MC, 2007) |
| "To assess the presence of thiamine deficiency in congestive heart failure patients receiving furosemide therapy." | 3.72 | Thiamine deficiency in congestive heart failure patients receiving long term furosemide therapy. ( Almalki, Y; Donnelly, J; Healey, J; Smith, S; Vaillancourt, R; Zenuk, C, 2003) |
| "Prolonged furosemide treatment is associated with urinary loss of thiamine and thiamine deficiency in some patients with congestive heart failure and low dietary thiamine intake." | 3.70 | Urinary loss of thiamine is increased by low doses of furosemide in healthy volunteers. ( Almog, S; Ezra, D; Halkin, H; Lubetsky, A; Olchovsky, D; Rieck, J; Seligman, H, 1999) |
| "Thiamine deficiency as a cause for an elevated serum lactate or lactate acidosis with or without cardiovascular failure may not be overlooked." | 3.70 | [Unclear lactate acidosis in a patient with heart failure under long-term diuretic therapy]. ( Duell, T; Hiddemann, W; Mittermüller, J, 2000) |
| "To test the hypothesis that long-term furosemide therapy in patients with congestive heart failure (CHF) is associated with clinically significant thiamine deficiency via urinary loss." | 3.68 | Thiamine deficiency in patients with congestive heart failure receiving long-term furosemide therapy: a pilot study. ( Ezra, D; Halkin, H; Kaufmann, N; Motro, M; Rauchfleisch, S; Seligmann, H; Vered, Z, 1991) |
| "Thiamine levels were determined using the erythrocyte transketolase activity." | 2.73 | Influence of spironolactone therapy on thiamine blood levels in patients with heart failure. ( Albanesi Filho, FM; de Albuquerque, DC; Rocha, RM; Silva, GV; Tura, BR, 2008) |
| " The changes in the ETK (erythrocyte transketolase activity in whole blood) and a-ETK (ETK activity coefficient) during the hospital stay correlated with the cumulative dosage of furosemide adjusted for the duration of the therapy (r = 0." | 1.31 | Diuretic use: a risk for subclinical thiamine deficiency in elderly patients. ( Haller, J; Hany, A; Suter, PM; Vetter, W, 2000) |
| " Thus, it is assumed that long-term administration of furosemide could induce a thiamine deficiency." | 1.26 | Furosemide-induced thiamine deficiency. ( Itokawa, Y; Kawai, C; Yui, Y, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gundogan, K | 1 |
| Akbudak, IH | 1 |
| Bulut, K | 1 |
| Temel, S | 1 |
| Sungur, M | 1 |
| Guven, M | 1 |
| Dave, NJ | 1 |
| Griffith, DP | 1 |
| Ziegler, TR | 1 |
| Nazmi, A | 1 |
| Weatherall, M | 1 |
| Wilkins, B | 1 |
| Robinson, GM | 1 |
| Katta, N | 1 |
| Balla, S | 1 |
| Alpert, MA | 1 |
| Teigen, LM | 1 |
| Twernbold, DD | 1 |
| Miller, WL | 1 |
| Rocha, RM | 1 |
| Silva, GV | 1 |
| de Albuquerque, DC | 1 |
| Tura, BR | 1 |
| Albanesi Filho, FM | 1 |
| Zenuk, C | 1 |
| Healey, J | 1 |
| Donnelly, J | 1 |
| Vaillancourt, R | 1 |
| Almalki, Y | 1 |
| Smith, S | 1 |
| da Cunha, S | 1 |
| Cunha Bastos, J | 1 |
| Salles, JB | 1 |
| Silva, MC | 1 |
| Cunha Bastos, VL | 1 |
| Mandarim-de-Lacerda, CA | 1 |
| Ono, Y | 1 |
| Makita, Z | 1 |
| Nakayama, H | 1 |
| Nakagawa, S | 1 |
| Tashiro, K | 1 |
| Yui, Y | 1 |
| Itokawa, Y | 1 |
| Kawai, C | 1 |
| Brady, JA | 1 |
| Rock, CL | 1 |
| Horneffer, MR | 1 |
| Shimon, I | 1 |
| Almog, S | 3 |
| Vered, Z | 2 |
| Seligmann, H | 3 |
| Shefi, M | 1 |
| Peleg, E | 1 |
| Rosenthal, T | 1 |
| Motro, M | 2 |
| Halkin, H | 4 |
| Ezra, D | 4 |
| Pfitzenmeyer, P | 1 |
| Guilland, JC | 1 |
| d'Athis, P | 1 |
| Petit-Marnier, C | 1 |
| Gaudet, M | 1 |
| Leslie, D | 1 |
| Gheorghiade, M | 1 |
| Rieck, J | 1 |
| Seligman, H | 1 |
| Lubetsky, A | 2 |
| Olchovsky, D | 2 |
| Winaver, J | 1 |
| Suter, PM | 1 |
| Haller, J | 1 |
| Hany, A | 1 |
| Vetter, W | 1 |
| Ali, BH | 1 |
| Al-Qarawi, AA | 1 |
| Duell, T | 1 |
| Mittermüller, J | 1 |
| Hiddemann, W | 1 |
| Rauchfleisch, S | 1 |
| Kaufmann, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs: Randomized Controlled Trial[NCT03989700] | Phase 3 | 60 participants (Anticipated) | Interventional | 2019-07-01 | Not yet recruiting | ||
| Thiamine Supplementation in High Risk Cardiac Surgery Patients[NCT03306732] | Phase 4 | 40 participants (Actual) | Interventional | 2017-10-19 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for furosemide and Deficiency, Thiamine
| Article | Year |
|---|---|
Does Long-Term Furosemide Therapy Cause Thiamine Deficiency in Patients with Heart Failure? A Focused Review.
Topics: Dietary Supplements; Furosemide; Heart Failure; Humans; Sodium Potassium Chloride Symporter Inhibito | 2016 |
Is there a role for thiamine supplementation in the management of heart failure?
Topics: Diuretics; Furosemide; Heart Failure; Humans; Thiamine; Thiamine Deficiency | 1996 |
3 trials available for furosemide and Deficiency, Thiamine
| Article | Year |
|---|---|
Influence of spironolactone therapy on thiamine blood levels in patients with heart failure.
Topics: Aged; Aged, 80 and over; Chi-Square Distribution; Chronic Disease; Cross-Sectional Studies; Diuretic | 2008 |
Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy.
Topics: Aged; Aged, 80 and over; Diuresis; Double-Blind Method; Echocardiography; Erythrocytes; Female; Furo | 1995 |
Thiamine status of elderly patients with cardiac failure including the effects of supplementation.
Topics: Aged; Aged, 80 and over; Female; Furosemide; Heart Diseases; Humans; Male; Nutritional Status; Thiam | 1994 |
14 other studies available for furosemide and Deficiency, Thiamine
| Article | Year |
|---|---|
Thiamin Status in Adults Receiving Chronic Diuretic Therapy Prior to Admission to a Medical Intensive Care Unit: A Pilot Study.
Topics: Adult; Aged; Case-Control Studies; Critical Illness; Diuretics; Female; Furosemide; Hospitalization; | 2019 |
Thiamin concentration in geriatric hospitalized patients using frusemide.
Topics: Aged; Aged, 80 and over; Aging; Diuretics; Female; Furosemide; Glomerular Filtration Rate; Heart Fai | 2014 |
Prevalence of thiamine deficiency in a stable heart failure outpatient cohort on standard loop diuretic therapy.
Topics: Aged; Cross-Sectional Studies; Diuretics; Female; Furosemide; Heart Failure; Humans; Male; Outpatien | 2016 |
Thiamine deficiency in congestive heart failure patients receiving long term furosemide therapy.
Topics: Aged; Diuretics; Female; Furosemide; Heart Failure; Humans; Male; Middle Aged; Prevalence; Thiamine | 2003 |
Cardiac alterations in furosemide-treated thiamine-deprived rats.
Topics: Animals; Cardiomyopathies; Diuretics; Furosemide; Health Status; Male; Myocardium; Nutritional Statu | 2007 |
[Case of probable Wernicke's encephalopathy following administration of a massive dosage of furosemide].
Topics: Furosemide; Humans; Male; Middle Aged; Thiamine Deficiency; Wernicke Encephalopathy | 1983 |
Furosemide-induced thiamine deficiency.
Topics: Animals; Enzyme Activation; Furosemide; Male; Rats; Thiamine; Thiamine Deficiency; Thiamine Pyrophos | 1980 |
Thiamin status, diuretic medications, and the management of congestive heart failure.
Topics: Adult; Aged; Bumetanide; Cross-Sectional Studies; Diet Records; Female; Food-Drug Interactions; Furo | 1995 |
Urinary loss of thiamine is increased by low doses of furosemide in healthy volunteers.
Topics: Adult; Animals; Diuresis; Diuretics; Dose-Response Relationship, Drug; Female; Furosemide; Heart Fai | 1999 |
Urinary thiamine excretion in the rat: effects of furosemide, other diuretics, and volume load.
Topics: Animals; Diuresis; Diuretics; Furosemide; Heart Failure; Humans; Kidney; Male; Mannitol; Natriuresis | 1999 |
Diuretic use: a risk for subclinical thiamine deficiency in elderly patients.
Topics: Aged; Aged, 80 and over; Aging; Diuretics; Dose-Response Relationship, Drug; Erythrocytes; Female; F | 2000 |
Thiamin status in furosemide-treated rats.
Topics: Animals; Diuretics; Dose-Response Relationship, Drug; Furosemide; Male; Rats; Rats, Sprague-Dawley; | 2000 |
[Unclear lactate acidosis in a patient with heart failure under long-term diuretic therapy].
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Diuretics; Dyspnea; Furosemide; Heart Failure; Humans; La | 2000 |
Thiamine deficiency in patients with congestive heart failure receiving long-term furosemide therapy: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Erythrocytes; Female; Furosemide; Heart Failure; Humans; Injections, | 1991 |