Page last updated: 2024-10-27

furosemide and Deafness

furosemide has been researched along with Deafness in 41 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Deafness: A general term for the complete loss of the ability to hear from both ears.

Research Excerpts

ExcerptRelevanceReference
"Ototoxicity was produced by the combinations of a constant dose of AMI (500 mg/kg; i."5.91N-Acetyl-L-cysteine Affects Ototoxicity Evoked by Amikacin and Furosemide Either Alone or in Combination in a Mouse Model of Hearing Threshold Decrease. ( Szymański, M; Zadrożniak, M; Łuszczki, JJ, 2023)
"A patient with Hodgkin's disease and renal insufficiency became deaf while being treated with high dose oral furosemide."5.26Deafness associated with oral furosemide. ( de Quesada, AM; Pickering, MJ; Rifkin, SI; Shires, DL, 1978)
"Children with hearing loss had lower birth weight for gestational age, more severe neonatal illness, with increased exposure to inotrope, steroid, gentamicin, vancomycin and furosemide, and more frequent physiological risk, elevated bilirubin and creatinine levels and acidosis, but no index child was found to have the m."4.31Cumulative risk factors contributing to hearing loss in preterm infants. ( Bitner-Glindzicz, M; Chant, K; Marlow, N, 2023)
"Kanamycin (500 mg/kg) and furosemide (50 mg/kg) were given to the healthy adult guinea pigs intramuscularly and intravenously to establish the deafness model."3.79[Math1 gene therapy for kanamycin and furosemide-induced deaf guinea pigs]. ( Gao, J; Guo, WW; Han, DY; Li, Z; Sun, AL; Sun, DX; Sun, JH; Wei, XN; Yang, SM; Zhang, XF, 2013)
" The present work reports the consequences on high- vs low-level DPOAEs of three types of cochlear impairments involving OHCs: progressive OHC degeneration of genetic origin in CD1 mice, complete cochlear ischemia in gerbils, and furosemide injection vs ischemia-reperfusion in gerbils."3.72Physiopathological significance of distortion-product otoacoustic emissions at 2f1-f2 produced by high- versus low-level stimuli. ( Avan, P; Bonfils, P; Gilain, L; Mom, T, 2003)
"Ototoxicity was produced by the combinations of a constant dose of AMI (500 mg/kg; i."1.91N-Acetyl-L-cysteine Affects Ototoxicity Evoked by Amikacin and Furosemide Either Alone or in Combination in a Mouse Model of Hearing Threshold Decrease. ( Szymański, M; Zadrożniak, M; Łuszczki, JJ, 2023)
" Therefore, a reproducible and safe model for hearing-impaired animals is essential."1.72The ototoxic effect of locally applied kanamycin and furosemide in guinea pigs. ( Bako, P; Gerlinger, I; Löwenheim, H; Müller, M; Wolpert, S, 2022)
"Thirty-five neonates with sensorineural hearing loss (SNHL), identified by brainstem auditory evoked response (BAER), and 70 matched controls with normal BAERs were studied."1.28Neonatal sensorineural hearing loss associated with furosemide: a case-control study. ( Brown, DR; Sabo, D; Watchko, JF, 1991)
"A patient with Hodgkin's disease and renal insufficiency became deaf while being treated with high dose oral furosemide."1.26Deafness associated with oral furosemide. ( de Quesada, AM; Pickering, MJ; Rifkin, SI; Shires, DL, 1978)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199017 (41.46)18.7374
1990's3 (7.32)18.2507
2000's11 (26.83)29.6817
2010's5 (12.20)24.3611
2020's5 (12.20)2.80

Authors

AuthorsStudies
Bako, P1
Gerlinger, I1
Wolpert, S1
Müller, M1
Löwenheim, H1
Chant, K1
Bitner-Glindzicz, M1
Marlow, N1
Zadrożniak, M1
Szymański, M1
Łuszczki, JJ1
Chen, J1
Liu, Z1
Yan, H1
Xing, W1
Mi, W1
Wang, R1
Li, W1
Chen, F1
Qiu, J1
Zha, D1
Ramekers, D3
Klis, SFL1
Versnel, H5
Waaijer, L1
Klis, SF5
Van Deurzen, MH1
Hendriksen, FG1
Grolman, W3
Mesbahzadeh, B1
Ajalloueyan, M1
Kaka, GR1
Askari, A1
Hasanalifard, M1
Zhang, XF1
Yang, SM1
Han, DY1
Guo, WW1
Sun, JH1
Gao, J1
Sun, DX1
Sun, AL1
Li, Z1
Wei, XN1
Havenith, S1
Song, BN1
Li, YX1
Han, DM1
Agterberg, MJ3
van Dijk, LM1
de Groot, JC3
Oesterle, EC1
Campbell, S1
van Loon, MC1
Avan, P1
Bonfils, P1
Gilain, L1
Mom, T1
Rais-Bahrami, K1
Majd, M1
Veszelovszky, E1
Short, BL1
Wise, AK1
Richardson, R1
Hardman, J1
Clark, G1
O'leary, S1
Smoorenburg, GF1
Nourski, KV1
Abbas, PJ1
Miller, CA1
Robinson, BK1
Jeng, FC1
Hurley, PA1
Crook, JM1
Shepherd, RK1
Arnold, W1
Nadol, JB1
Weidauer, H1
Aso, S1
Watanabe, Y1
Lima da Costa, D1
Erre, JP1
Charlet de Sauvage, R1
Popelar, J1
Aran, JM1
Konrad-Martin, D1
Norton , SJ1
Mascher, KE1
Tempel, BL1
Cook, DJ1
Tudball, CF1
Iaroshevich, VI1
Bourke, E1
Laitakari, K1
Rifkin, SI1
de Quesada, AM1
Pickering, MJ1
Shires, DL1
Brown, DR1
Watchko, JF1
Sabo, D1
Lynn, AM1
Redding, GJ1
Morray, JP1
Tyler, DC1
Lloyd-Mostyn, RH1
Lord, IJ1
Siciński, A1
Brown, CB1
Ogg, CS1
Cameron, JS1
Bewick, M1
Stenbaek, O1
Venkateswaran, PS1
Schwartz, GH1
David, DS2
Riggio, RR1
Stenzel, KH1
Rubin, AL1
Vargish, T1
Benjamin, R1
Shenkman, L1
Heidland, A2
Wigand, ME2
Hitzig, P1
Klockhoff, I1
Lindblom, U1

Reviews

1 review available for furosemide and Deafness

ArticleYear
[Advances in nephrology. Chronic renal failure].
    Polskie Archiwum Medycyny Wewnetrznej, 1974, Volume: 52, Issue:2

    Topics: Bone and Bones; Cataract; Deafness; Female; Furosemide; Gastrointestinal Diseases; Humans; Hypercalc

1974

Trials

1 trial available for furosemide and Deafness

ArticleYear
High dose frusemide in acute reversible intrinsic renal failure. A preliminary communication.
    Scottish medical journal, 1974, Volume: 19 Suppl 1

    Topics: Acute Kidney Injury; Adult; Clinical Trials as Topic; Deafness; Furosemide; Gentamicins; Humans; Kan

1974

Other Studies

39 other studies available for furosemide and Deafness

ArticleYear
The ototoxic effect of locally applied kanamycin and furosemide in guinea pigs.
    Journal of neuroscience methods, 2022, Apr-15, Volume: 372

    Topics: Animals; Cochlea; Deafness; Furosemide; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Spiral Ganglio

2022
Cumulative risk factors contributing to hearing loss in preterm infants.
    Archives of disease in childhood. Fetal and neonatal edition, 2023, Volume: 108, Issue:5

    Topics: Case-Control Studies; Child; Deafness; Furosemide; Gentamicins; Hearing Loss; Humans; Infant; Infant

2023
N-Acetyl-L-cysteine Affects Ototoxicity Evoked by Amikacin and Furosemide Either Alone or in Combination in a Mouse Model of Hearing Threshold Decrease.
    International journal of molecular sciences, 2023, Apr-20, Volume: 24, Issue:8

    Topics: Acetylcysteine; Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Auditory Threshold; Deafn

2023
miR-182 prevented ototoxic deafness induced by co-administration of kanamycin and furosemide in rats.
    Neuroscience letters, 2020, 04-01, Volume: 723

    Topics: Animals; Anti-Bacterial Agents; Deafness; Drug Combinations; Female; Furosemide; Kanamycin; MicroRNA

2020
Simultaneous rather than retrograde spiral ganglion cell degeneration following ototoxically induced hair cell loss in the guinea pig cochlea.
    Hearing research, 2020, Volume: 390

    Topics: Animals; Auditory Threshold; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, Brain St

2020
The peripheral processes of spiral ganglion cells after intracochlear application of brain-derived neurotrophic factor in deafened guinea pigs.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2013, Volume: 34, Issue:3

    Topics: Animals; Brain-Derived Neurotrophic Factor; Deafness; Furosemide; Guinea Pigs; Hair Cells, Auditory;

2013
A model portraying experimental loss of hair cell: the use of distortion product otoacoustic emission in the assessment of rat's ear.
    Pakistan journal of pharmaceutical sciences, 2013, Volume: 26, Issue:4

    Topics: Amikacin; Animals; Deafness; Disease Models, Animal; Furosemide; Hair Cells, Auditory; Male; Otoacou

2013
[Math1 gene therapy for kanamycin and furosemide-induced deaf guinea pigs].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2013, Volume: 48, Issue:7

    Topics: Adenoviridae; Animals; Basic Helix-Loop-Helix Transcription Factors; Cochlea; Deafness; Ear, Inner;

2013
Local delivery of brain-derived neurotrophic factor on the perforated round window membrane in Guinea pigs: a possible clinical application.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2015, Volume: 36, Issue:4

    Topics: Animals; Brain-Derived Neurotrophic Factor; Deafness; Disease Models, Animal; Drug Administration Ro

2015
Delayed electrical stimulation and BDNF application following induced deafness in rats.
    Acta oto-laryngologica, 2009, Volume: 129, Issue:2

    Topics: Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Survival; Cochlea; Combined Mod

2009
Enhanced survival of spiral ganglion cells after cessation of treatment with brain-derived neurotrophic factor in deafened guinea pigs.
    Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:3

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cochlear Implants; Deafness; Electric Sti

2009
Supporting cell characteristics in long-deafened aged mouse ears.
    Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:4

    Topics: Aging; Animals; Biomarkers; Calcium-Binding Proteins; Cell Differentiation; Deafness; Diuretics; Fur

2009
Spiral ganglion cell morphology in guinea pigs after deafening and neurotrophic treatment.
    Hearing research, 2013, Volume: 298

    Topics: Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Shape; Cell Size; Cell Survival

2013
Physiopathological significance of distortion-product otoacoustic emissions at 2f1-f2 produced by high- versus low-level stimuli.
    The Journal of the Acoustical Society of America, 2003, Volume: 113, Issue:1

    Topics: Acoustic Stimulation; Animals; Auditory Threshold; Brain Stem; Cochlea; Deafness; Disease Models, An

2003
Use of furosemide and hearing loss in neonatal intensive care survivors.
    American journal of perinatology, 2004, Volume: 21, Issue:6

    Topics: Auditory Threshold; Brain Stem; Deafness; District of Columbia; Diuretics; Female; Furosemide; Heari

2004
Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3.
    The Journal of comparative neurology, 2005, Jun-27, Volume: 487, Issue:2

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Count; Cell Survival; Cochlea; Cochlear Implantatio

2005
Time course of cochlear electrophysiology and morphology after combined administration of kanamycin and furosemide.
    Hearing research, 2007, Volume: 231, Issue:1-2

    Topics: Action Potentials; Animals; Anti-Bacterial Agents; Cell Survival; Cochlea; Deafness; Electrophysiolo

2007
Acoustic-electric interactions in the guinea pig auditory nerve: simultaneous and forward masking of the electrically evoked compound action potential.
    Hearing research, 2007, Volume: 232, Issue:1-2

    Topics: Acoustic Stimulation; Adaptation, Physiological; Animals; Auditory Perception; Cochlear Nerve; Deafn

2007
Schwann cells revert to non-myelinating phenotypes in the deafened rat cochlea.
    The European journal of neuroscience, 2007, Volume: 26, Issue:7

    Topics: Animals; Animals, Newborn; Cochlea; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, B

2007
Temporal bone histopathology in human ototoxicity due to loop diuretics.
    Scandinavian audiology. Supplementum, 1981, Volume: 14 Suppl

    Topics: Cochlea; Deafness; Diuretics; Ethacrynic Acid; Furosemide; Humans; Male; Middle Aged; Temporal Bone

1981
Electrocochleography in the diagnosis of delayed endolymphatic hydrops.
    Acta oto-laryngologica. Supplementum, 1994, Volume: 511

    Topics: Action Potentials; Adolescent; Adult; Aged; Aged, 80 and over; Audiometry, Evoked Response; Child; D

1994
Bioelectrical cochlear noise and its contralateral suppression: relation to background activity of the eighth nerve and effects of sedation and anesthesia.
    Experimental brain research, 1997, Volume: 116, Issue:2

    Topics: Acoustic Stimulation; Aminoglycosides; Anesthesia; Animals; Anti-Bacterial Agents; Body Temperature;

1997
Effects of PMCA2 mutation on DPOAE amplitudes and latencies in deafwaddler mice.
    Hearing research, 2001, Volume: 151, Issue:1-2

    Topics: Animals; Calcium-Transporting ATPases; Cation Transport Proteins; Deafness; Furosemide; Hair Cells,

2001
Potentiators and bolus intravenous furosemide.
    Lancet (London, England), 2001, Oct-20, Volume: 358, Issue:9290

    Topics: Child; Deafness; Diuretics; Dose-Response Relationship, Drug; Furosemide; Humans; Infant, Newborn; R

2001
[Ototoxicity of some drug agents].
    Voenno-meditsinskii zhurnal, 1975, Issue:10

    Topics: Age Factors; Aminoglycosides; Bleomycin; Cochlea; Deafness; Dimethyl Sulfoxide; Dose-Response Relati

1975
Letter: Frusemide, bumetanide, and ototoxicity.
    Lancet (London, England), 1976, Apr-24, Volume: 1, Issue:7965

    Topics: Bumetanide; Deafness; Diuretics; Edema; Female; Furosemide; Humans; Hyperparathyroidism; Male; Middl

1976
Vestibular disorders in medically managed chronic renal insufficiency.
    Acta oto-laryngologica. Supplementum, 1977, Volume: 349

    Topics: Adolescent; Adult; Aged; Audiometry; Caloric Tests; Deafness; Ear; Electronystagmography; Female; Fu

1977
Deafness associated with oral furosemide.
    Southern medical journal, 1978, Volume: 71, Issue:1

    Topics: Aged; Audiometry; Deafness; Furosemide; Hodgkin Disease; Humans; Male; Nephrotic Syndrome; Prednison

1978
Neonatal sensorineural hearing loss associated with furosemide: a case-control study.
    Developmental medicine and child neurology, 1991, Volume: 33, Issue:9

    Topics: Auditory Threshold; Brain Stem; Child, Preschool; Deafness; Evoked Potentials, Auditory, Brain Stem;

1991
Isolated deafness following recovery from neurologic injury and adult respiratory distress syndrome. A sequela of intercurrent aminoglycoside and diuretic use.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:5

    Topics: Aminoglycosides; Anti-Bacterial Agents; Deafness; Diuresis; Furosemide; Hearing Tests; Humans; Infan

1985
Ototoxicity of intravenous frusemide.
    Lancet (London, England), 1971, Nov-20, Volume: 2, Issue:7734

    Topics: Aged; Audiometry; Deafness; Discrimination, Psychological; Furosemide; Hearing Disorders; Humans; In

1971
[Furosemide-induced deafness in decreased kidney function].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Sep-30, Volume: 92, Issue:27

    Topics: Administration, Oral; Deafness; Furosemide; Humans; Infusions, Parenteral; Kidney Diseases

1972
Transient deafness from high doses of frusemide.
    British medical journal, 1971, Oct-09, Volume: 4, Issue:5779

    Topics: Deafness; Female; Furosemide; Humans; Kidney Failure, Chronic; Middle Aged

1971
Ototoxicity induced by furosemide.
    The New England journal of medicine, 1970, Jun-18, Volume: 282, Issue:25

    Topics: Adult; Deafness; Ear Diseases; Female; Furosemide; Humans; Injections, Intravenous; Kidney Diseases;

1970
Deafness from furosemide.
    Annals of internal medicine, 1970, Volume: 72, Issue:5

    Topics: Adult; Deafness; Furosemide; Humans; Kidney Failure, Chronic; Male

1970
Deafness from furosemide.
    Annals of internal medicine, 1970, Volume: 73, Issue:5

    Topics: Deafness; Furosemide; Humans

1970
Diuretics and ototoxicity.
    The New England journal of medicine, 1971, Jun-10, Volume: 284, Issue:23

    Topics: Adult; Deafness; Diuretics; Ethacrynic Acid; Female; Furosemide; Humans

1971
Ototoxic side-effects of high doses of frusemide in patients with uraemia.
    Postgraduate medical journal, 1971, Volume: 47

    Topics: Audiometry; Deafness; Furosemide; Humans; Organ of Corti; Time Factors; Uremia

1971
Glycerol test in Ménière's disease.
    Acta oto-laryngologica, 1966, Jun-27

    Topics: Audiometry; Deafness; Diuretics; Ear, Inner; Furosemide; Glycerol; Humans; Labyrinthine Fluids; Male

1966