furosemide has been researched along with Cystic Fibrosis in 19 studies
Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacokinetics of furosemide and its diuretic effect were studied in six patients with cystic fibrosis (CF) and in six age-matched healthy volunteers." | 7.67 | Increased nonrenal clearance and increased diuretic efficiency of furosemide in cystic fibrosis. ( Alván, G; Beermann, B; Hjelte, L; Lind, M; Lindholm, A; Strandvik, B, 1988) |
| " The bioavailability of furosemide, its mean absorption rate and the mean plasma and urinary elimination half-lives both of the oral and the intravenous drug were similar to those reported in normal subjects." | 5.28 | Diuretic effect and disposition of furosemide in cystic fibrosis. ( Hilman, BC; Prandota, J; Smith, IJ; Wilson, JT, 1991) |
| "In an attempt to produce an animal model for the disease cystic fibrosis (CF), mice were treated chronically with the diuretics amiloride and furosemide, in order to cause chronic inhibition of transepithelial ion transport." | 3.68 | Effect of chronic treatment with diuretics on mouse liver: a morphological and microanalytical investigation. ( Mörk, AC; Roomans, GM; von Euler, A, 1992) |
| "The pharmacokinetics of furosemide and its diuretic effect were studied in six patients with cystic fibrosis (CF) and in six age-matched healthy volunteers." | 3.67 | Increased nonrenal clearance and increased diuretic efficiency of furosemide in cystic fibrosis. ( Alván, G; Beermann, B; Hjelte, L; Lind, M; Lindholm, A; Strandvik, B, 1988) |
| "Treatment with amiloride or furosemide in utero caused a decrease in cellular sodium and chloride levels, indicative of inhibition of transepithelial ion and fluid transport." | 1.28 | Effects of chronic and in utero treatment with diuretics on mouse exocrine cells studied by X-ray microanalysis. ( Mörk, AC; Roomans, GM; Von Euler, A, 1992) |
| " The bioavailability of furosemide, its mean absorption rate and the mean plasma and urinary elimination half-lives both of the oral and the intravenous drug were similar to those reported in normal subjects." | 1.28 | Diuretic effect and disposition of furosemide in cystic fibrosis. ( Hilman, BC; Prandota, J; Smith, IJ; Wilson, JT, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (31.58) | 18.7374 |
| 1990's | 10 (52.63) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Spinelli, E | 1 |
| Timpano, S | 1 |
| Fogazzi, A | 1 |
| Dester, S | 1 |
| Milianti, S | 1 |
| Padoan, R | 1 |
| Verloo, P | 1 |
| Kocken, CH | 1 |
| Van der Wel, A | 1 |
| Tilly, BC | 1 |
| Hogema, BM | 1 |
| Sinaasappel, M | 1 |
| Thomas, AW | 1 |
| De Jonge, HR | 1 |
| Cuthbert, AW | 4 |
| Halstead, J | 1 |
| Ratcliff, R | 2 |
| Colledge, WH | 3 |
| Evans, MJ | 3 |
| MacVinish, LJ | 3 |
| Hickman, ME | 2 |
| Alton, EW | 1 |
| Kingsleigh-Smith, DJ | 1 |
| Munkonge, FM | 1 |
| Smith, SN | 1 |
| Lindsay, AR | 1 |
| Gruenert, DC | 1 |
| Jeffery, PK | 1 |
| Norris, A | 1 |
| Geddes, DM | 1 |
| Williams, AJ | 1 |
| Manson, AL | 1 |
| Trezise, AE | 1 |
| Kasschau, KD | 1 |
| Birchall, N | 1 |
| Episkopou, V | 1 |
| Vassaux, G | 1 |
| Huxley, C | 1 |
| Mörk, AC | 2 |
| von Euler, A | 2 |
| Roomans, GM | 4 |
| Prandota, J | 1 |
| Smith, IJ | 1 |
| Hilman, BC | 1 |
| Wilson, JT | 1 |
| Mastrocola, T | 1 |
| Rugolo, M | 1 |
| Sagström, S | 2 |
| McMillan, EB | 1 |
| Marijianowski, M | 1 |
| Mulders, H | 1 |
| Liedtke, CM | 1 |
| Szeifert, GT | 1 |
| Varga, E | 1 |
| Damjanovich, L | 1 |
| Gomba, S | 1 |
| Alván, G | 1 |
| Beermann, B | 1 |
| Hjelte, L | 1 |
| Lind, M | 1 |
| Lindholm, A | 1 |
| Strandvik, B | 1 |
| Martinez, JR | 2 |
| Martinez, AM | 1 |
| Scarlett, SM | 1 |
| Sagulin, GB | 1 |
| Cassity, N | 1 |
| Cipolla, D | 1 |
| Zhang, J | 1 |
| Korkmaz, B | 1 |
| Chalmers, JD | 1 |
| Basso, J | 1 |
| Lasala, D | 1 |
| Fernandez, C | 1 |
| Teper, A | 1 |
| Mange, KC | 1 |
| Perkins, WR | 1 |
| Sullivan, EJ | 1 |
1 trial available for furosemide and Cystic Fibrosis
| Article | Year |
|---|---|
Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial.
Topics: Bronchiectasis; Cystic Fibrosis; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Leukocyte | 2023 |
18 other studies available for furosemide and Cystic Fibrosis
| Article | Year |
|---|---|
18q deletion in a cystic fibrosis infant, increased morbidity and challenge for correct treatment choices: a case report.
Topics: Child, Preschool; Chromosome Deletion; Chromosomes, Human, Pair 18; Cystic Fibrosis; Diuretics; Foll | 2011 |
Plasmodium falciparum-activated chloride channels are defective in erythrocytes from cystic fibrosis patients.
Topics: Animals; Chlorides; Chlorine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; | 2004 |
The genetic advantage hypothesis in cystic fibrosis heterozygotes: a murine study.
Topics: Animals; Bacterial Toxins; Calcium; Carbachol; Chloride Channels; Cholera Toxin; Colforsin; Colon; C | 1995 |
Ion-transporting activity in the murine colonic epithelium of normal animals and animals with cystic fibrosis.
Topics: Amiloride; Animals; Biological Transport; Carbachol; Colforsin; Colon; Cystic Fibrosis; Epithelium; | 1994 |
Asthma prophylaxis agents alter the function of an airway epithelial chloride channel.
Topics: Animals; Anti-Asthmatic Agents; Calcium; Cell Line; Chloride Channels; Cromolyn Sodium; Cystic Fibro | 1996 |
Complementation of null CF mice with a human CFTR YAC transgene.
Topics: Animals; Carbachol; Chlorides; Chromosomes, Artificial, Yeast; Colforsin; Cystic Fibrosis; Cystic Fi | 1997 |
Formal analysis of electrogenic sodium, potassium, chloride and bicarbonate transport in mouse colon epithelium.
Topics: Acetazolamide; Amiloride; Animals; Bicarbonates; Biological Transport; Chlorides; Colforsin; Colon; | 1999 |
Effect of chronic treatment with diuretics on mouse liver: a morphological and microanalytical investigation.
Topics: Amiloride; Animals; Cystic Fibrosis; Disease Models, Animal; Electron Probe Microanalysis; Female; F | 1992 |
Effects of chronic and in utero treatment with diuretics on mouse exocrine cells studied by X-ray microanalysis.
Topics: Amiloride; Animals; Animals, Newborn; Anions; Cystic Fibrosis; Disease Models, Animal; Diuretics; El | 1992 |
Diuretic effect and disposition of furosemide in cystic fibrosis.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Child; Cystic Fibrosis; Diuresis; | 1991 |
The response of chloride transport to cyclic AMP, calcium and hypotonic shock in normal and cystic fibrosis fibroblasts.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Calcimycin; Calcium; Cell Line; Cells, Cultured | 1990 |
Changes in rat and mouse salivary glands and pancreas after chronic treatment with diuretics: a potential animal model for cystic fibrosis.
Topics: Acetazolamide; Amiloride; Animals; Biological Transport; Chlorides; Cystic Fibrosis; Disease Models, | 1990 |
Alpha-adrenergic regulation of Na-Cl cotransport in human airway epithelium.
Topics: Carrier Proteins; Chlorides; Cystic Fibrosis; Epinephrine; Epithelium; Furosemide; Humans; Intracell | 1989 |
The chronically furosemide-treated mouse as a possible ultrastructural model for cystic fibrosis.
Topics: Animals; Chlorides; Cystic Fibrosis; Cytoplasmic Granules; Disease Models, Animal; Enzyme Precursors | 1987 |
Increased nonrenal clearance and increased diuretic efficiency of furosemide in cystic fibrosis.
Topics: Adolescent; Adult; Cystic Fibrosis; Diuresis; Electrolytes; Female; Furosemide; Humans; Kidney; Male | 1988 |
The reserpine-treated rat as an experimental animal model for cystic fibrosis: abnormal Cl transport in pancreatic acinar cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1988 |
Effects of chronic furosemide treatment on rat exocrine glands.
Topics: Animals; Biological Transport; Cations; Chlorides; Cystic Fibrosis; Disease Models, Animal; Exocrine | 1988 |
The chronically reserpinized rat as a model for cystic fibrosis: abnormal Cl- transport as the basis for reduced salivary fluid secretion.
Topics: Acetylcholine; Animals; Biological Transport; Chlorides; Cystic Fibrosis; Electrolytes; Furosemide; | 1985 |