Page last updated: 2024-10-27

furosemide and Coronary Disease

furosemide has been researched along with Coronary Disease in 39 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"This is a prospective randomized controlled trial to study the efficacy and safety of Shenfu injection combined with furosemide in the treatment of coronary heart disease and chronic heart failure."9.41Shenfu injection combined with furosemide in the treatment of chronic heart failure in patients with coronary heart disease: A protocol of randomized controlled trial. ( Gao, Y; Tan, X; Zhu, R, 2021)
"Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates."7.66Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978)
"Ibopamine is a novel oral dopamine analogue with positive inotropy and diuretic effects."6.67[Renal effects of ibopamine in comparison with furosemide in patients with mild heart failure]. ( Gerzer, R; Theisen, K; Wehling, M; Weil, J; Zimmermann, J, 1990)
"This is a prospective randomized controlled trial to study the efficacy and safety of Shenfu injection combined with furosemide in the treatment of coronary heart disease and chronic heart failure."5.41Shenfu injection combined with furosemide in the treatment of chronic heart failure in patients with coronary heart disease: A protocol of randomized controlled trial. ( Gao, Y; Tan, X; Zhu, R, 2021)
"Severe tachycardia, ventricular ectopy, and sodium retention manifested by hemodynamic deterioration developed with hydralazine hydrochloride therapy in chronic coronary heart disease with congestive failure refractory to digitalis, diuretics, and nitrates."3.66Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy. ( Amsterdam, EA; DeMaria, AN; Laslett, LJ; Mason, DT, 1978)
" On long term evaluation in an open design (Phase II), wherein Phase I participants continued Terminalia Arjuna in fixed dosage (500 mg 8-hourly) in addition to flexible diuretic, vasodilator and digitalis dosage for 20-28 months (mean 24 months) on outpatient basis, patients showed continued improvement in symptoms, signs, effort tolerance and NYHA Class, with improvement in quality of life."2.68Salutary effect of Terminalia Arjuna in patients with severe refractory heart failure. ( Bharani, A; Bhargava, KD; Ganguly, A, 1995)
"Ibopamine is a novel oral dopamine analogue with positive inotropy and diuretic effects."2.67[Renal effects of ibopamine in comparison with furosemide in patients with mild heart failure]. ( Gerzer, R; Theisen, K; Wehling, M; Weil, J; Zimmermann, J, 1990)
"In 50 patients with chronic congestive heart failure (CCHF, III or IV class), aged 62."2.67[Effect of vasodilator agents on the character and incidence of cardiac arrhythmia in chronic heart failure]. ( Bechler-Lisińska, J; Cholewa, M; Górski, L; Markiewicz, K, 1990)
"The treatment of acute cardiogenic pulmonary edema is associated with the return of hypo-oncotic fluid from the interstitial compartment back into the intravascular compartment with expansion of plasma volume and reduction of colloid osmotic pressure and hemoglobin concentration."1.26Effect of afterload reduction on plasma volume during acute heart failure. ( Henning, RJ; Weil, MH, 1978)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199030 (76.92)18.7374
1990's5 (12.82)18.2507
2000's3 (7.69)29.6817
2010's0 (0.00)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Gao, Y2
Zhu, R1
Tan, X1
POLETTI, T1
BELLARDO, G1
MASCARELLO, M1
Norris, W1
Kunzelman, KS1
Bussell, S1
Rohweder, L1
Cochran, RP1
Brunckhorst, CB1
Bazhenov, AN1
Kol'tsova, IV1
Iaroshenko, GA1
Bart, BIa1
Pashkova, TL1
Stepanov, NG1
Orlova, TV1
Kalmanova, EN1
Rumeau, M1
Pourrat, J1
Chambeu, Y1
Livshits, IB1
Morgan, DB1
Davidson, C1
Nechwatal, W1
Sigel, H1
Bitter, F1
Geffers, H1
Kress, P1
Adam, WE1
Stauch, M1
Bharani, A1
Ganguly, A1
Bhargava, KD1
Stevens, MA1
McCullough, PA1
Tobin, KJ1
Speck, JP1
Westveer, DC1
Guido-Allen, DA1
Timmis, GC1
O'Neill, WW1
Wilhelmsen, L1
Berglund, G1
Sannerstedt, R1
Hansson, L1
Andersson, O1
Sievertsson, R1
Wikstrand, J1
Houston, CS1
Dickinson, J1
Swartz, C1
Kim, KE1
Laslett, LJ1
DeMaria, AN1
Amsterdam, EA1
Mason, DT1
Henning, RJ1
Weil, MH1
Schenk, KE2
Biamino, G2
Schröder, R2
Leitner, ER1
Perchikova, GE1
Tsibekmakher, TD1
Somova, LV1
Mitani, A1
Shattock, MJ1
Wehling, M1
Zimmermann, J1
Weil, J1
Gerzer, R1
Theisen, K1
Bechler-Lisińska, J1
Cholewa, M1
Górski, L1
Markiewicz, K1
Nemirovskaia, MA1
Zharov, EI1
Vertkin, AL1
Borchgrevink, PC1
Jynge, P1
Houston, MC1
Johnston, PE1
Weser, C1
Scheidler, K1
Teichmann, G1
Löper, W1
Kolff, J1
Cheanvechai, C1
Viljoen, JF1
Sidorenko, BA2
Kharchenko, VI2
Titov, VN1
Lotova, EV1
Mel'nichenko, GA2
Cohen, H1
Langendorf, R1
Pick, A1
Rotsztain, A1
Shugoll, GI1
Lloyd, RA1
Simon, H1
Schweikert, U1
Trübestein, G1
Esser, H1
Fricke, G1
Croxson, MS1
Neutze, JM1
John, MB1
Tolstykh, AN1
Sanna, GP1
Kliachko, VR1
Shaginova, EM1
Tirkina, TN1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Renal Insufficiency Following Contrast Media Administration Trial III (REMEDIAL III): Renalguard System Versus Left-ventricular End-diastolic Pressure-guided Hydration in High-risk Patients for Contrast-induced Acute Kidney Injury[NCT02489669]700 participants (Anticipated)Interventional2015-07-15Enrolling by invitation
Renal Insufficiency Following Contrast Media Administration Trial II (Remedial II): The RenalGuard System in High-Risk Patients for Contrast-Induced Acute Kidney Injury[NCT01098032]Phase 3294 participants (Actual)Interventional2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Contrast-induced Acute Kidney Injury

The primary outcome measure will be the rate of development of CI-AKI in the 2 study arms (number of participants). CI-AKI is defined as an increase in the serum creatinine concentration >=0.3 mg/dL from the baseline value at 48 hours after administration of the contrast media or the need for dialysis. (NCT01098032)
Timeframe: at 48 hours following contrast exposure

Interventionparticipants (Number)
Systemic Alone Therapy Group146
RenalGuard System Group146

Reviews

1 review available for furosemide and Coronary Disease

ArticleYear
Essential hypertension: new insights and controversies in treatment with diuretics.
    Southern medical journal, 1986, Volume: 79, Issue:8

    Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Coronary Disease; Diuretics; Dose-Response Relat

1986

Trials

9 trials available for furosemide and Coronary Disease

ArticleYear
Shenfu injection combined with furosemide in the treatment of chronic heart failure in patients with coronary heart disease: A protocol of randomized controlled trial.
    Medicine, 2021, Jan-22, Volume: 100, Issue:3

    Topics: Chronic Disease; Coronary Disease; Diuretics; Drug Therapy, Combination; Drugs, Chinese Herbal; Furo

2021
Potassium supplementation, diet vs pills: a randomized trial in postoperative cardiac surgery patients.
    Chest, 2004, Volume: 125, Issue:2

    Topics: Administration, Oral; Aged; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Disease; D

2004
Salutary effect of Terminalia Arjuna in patients with severe refractory heart failure.
    International journal of cardiology, 1995, Volume: 49, Issue:3

    Topics: Adult; Aged; Cardiomyopathy, Dilated; Chemotherapy, Adjuvant; Chronic Disease; Coronary Disease; Cro

1995
A prospective randomized trial of prevention measures in patients at high risk for contrast nephropathy: results of the P.R.I.N.C.E. Study. Prevention of Radiocontrast Induced Nephropathy Clinical Evaluation.
    Journal of the American College of Cardiology, 1999, Volume: 33, Issue:2

    Topics: Aged; Cardiotonic Agents; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Crysta

1999
A prospective randomized trial of prevention measures in patients at high risk for contrast nephropathy: results of the P.R.I.N.C.E. Study. Prevention of Radiocontrast Induced Nephropathy Clinical Evaluation.
    Journal of the American College of Cardiology, 1999, Volume: 33, Issue:2

    Topics: Aged; Cardiotonic Agents; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Crysta

1999
A prospective randomized trial of prevention measures in patients at high risk for contrast nephropathy: results of the P.R.I.N.C.E. Study. Prevention of Radiocontrast Induced Nephropathy Clinical Evaluation.
    Journal of the American College of Cardiology, 1999, Volume: 33, Issue:2

    Topics: Aged; Cardiotonic Agents; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Crysta

1999
A prospective randomized trial of prevention measures in patients at high risk for contrast nephropathy: results of the P.R.I.N.C.E. Study. Prevention of Radiocontrast Induced Nephropathy Clinical Evaluation.
    Journal of the American College of Cardiology, 1999, Volume: 33, Issue:2

    Topics: Aged; Cardiotonic Agents; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Crysta

1999
[Haemodynamic effects of furosemide and ethacrynic acid (author's transl)].
    Klinische Wochenschrift, 1975, Dec-01, Volume: 53, Issue:23

    Topics: Acute Disease; Blood Pressure; Blood Vessels; Coronary Disease; Ethacrynic Acid; Furosemide; Heart;

1975
[Nitroglycerin, furosemide and ethacrynic acid effect on hemodynamics in rest and during ergometric load in coronary disease patients].
    Zeitschrift fur Kardiologie, 1976, Volume: 65, Issue:1

    Topics: Blood Pressure; Blood Volume; Cardiac Output; Coronary Disease; Ethacrynic Acid; Exercise Test; Furo

1976
[Renal effects of ibopamine in comparison with furosemide in patients with mild heart failure].
    Zeitschrift fur Kardiologie, 1990, Volume: 79, Issue:2

    Topics: Atrial Natriuretic Factor; Blood Pressure; Cardiomyopathy, Dilated; Coronary Disease; Cyclic GMP; De

1990
[Effect of vasodilator agents on the character and incidence of cardiac arrhythmia in chronic heart failure].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1990, Mar-01, Volume: 45, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Atrial Fibrillation; Captopril; Cardiac Output

1990
[Effect of vasodilator agents on the effectiveness of the complex treatment of patients with ischemic heart disease and congestive heart failure].
    Kardiologiia, 1989, Volume: 29, Issue:4

    Topics: Aged; Cardiomyopathy, Dilated; Clinical Trials as Topic; Coronary Disease; Digoxin; Drug Synergism;

1989

Other Studies

29 other studies available for furosemide and Coronary Disease

ArticleYear
[CLINICAL EXPERIENCES WITH FUROSEMIDE].
    Minerva medica, 1965, May-19, Volume: 56

    Topics: Coronary Disease; Diuretics; Furosemide; Geriatrics; Heart Diseases; Humans

1965
[CME-EKG 17. Coronary heart disease and arrhythmia].
    Praxis, 2007, Jun-20, Volume: 96, Issue:25-26

    Topics: Aged; Coronary Disease; Diagnosis, Differential; Electrocardiography; Erythromycin; Furosemide; Hear

2007
[Interaction of calcium drug and vitamin D3 with some medicines used in coronary heart disease therapy].
    Klinicheskaia meditsina, 2008, Volume: 86, Issue:3

    Topics: Calcium; Cholecalciferol; Coronary Disease; Diuretics; Drug Interactions; Female; Furosemide; Humans

2008
[Dilatation (congestive) cardiomyopathy: clinical aspects, diagnosis and treatment].
    Kardiologiia, 1984, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Cardiomegaly; Cardiomyopathy, Dilated; Coronary Disease; Diagnosis, Differential;

1984
[Effects of the PETN-piridoxylate combination in the long-term treatment of cardiac failure in the aged patient].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, May-12, Volume: 59, Issue:19

    Topics: Aged; Coronary Disease; Digoxin; Drug Combinations; Drug Therapy, Combination; Furosemide; Heart Fai

1983
[Effect of acute furosemide and sodium chloride load on the hormone level of the blood of ischemic heart disease patients].
    Kardiologiia, 1982, Volume: 22, Issue:3

    Topics: Adult; Coronary Disease; Female; Furosemide; Homeostasis; Hormones; Humans; Hyperlipoproteinemia Typ

1982
Hypokalaemia and diuretics: an analysis of publications.
    British medical journal, 1980, Mar-29, Volume: 280, Issue:6218

    Topics: Chlorothiazide; Chlorthalidone; Coronary Disease; Diuretics; Dose-Response Relationship, Drug; Furos

1980
[Global and regional left ventricular function in coronary heart disease after beta-blockade and furosemide (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Nov-28, Volume: 105, Issue:48

    Topics: Adult; Coronary Disease; Furosemide; Heart; Heart Ventricles; Humans; Middle Aged; Penbutolol; Physi

1980
Effect of treatment of hypertension in the primary preventive trial, Göteborg, Sweden.
    British journal of clinical pharmacology, 1979, Volume: 7 Suppl 2

    Topics: Adrenergic beta-Antagonists; Bethanidine; Cardiovascular Diseases; Cerebrovascular Disorders; Corona

1979
Cerebral form of high-altitude illness.
    Lancet (London, England), 1975, Oct-18, Volume: 2, Issue:7938

    Topics: Adult; Altitude Sickness; Betamethasone; Brain Edema; Bronchopneumonia; Coronary Disease; Dexamethas

1975
Treatment of complicated hypertension.
    New York state journal of medicine, 1977, Volume: 77, Issue:6

    Topics: Acute Disease; Cerebral Hemorrhage; Cerebrovascular Disorders; Chronic Disease; Coronary Disease; Di

1977
Hydralazine-induced tachycardia and sodium retention in heart failure. Hemodynamic and symptomatic correction by prazosin therapy.
    Archives of internal medicine, 1978, Volume: 138, Issue:5

    Topics: Aged; Coronary Disease; Digitalis Glycosides; Female; Furosemide; Heart Failure; Humans; Hydralazine

1978
Effect of afterload reduction on plasma volume during acute heart failure.
    The American journal of cardiology, 1978, Volume: 42, Issue:5

    Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Coronary Disease; Diastole; Drug Evaluation; Fe

1978
Diazoxide therapy: use and risks.
    Annals of internal medicine, 1976, Volume: 85, Issue:4

    Topics: Angina Pectoris; Blood Pressure; Coronary Disease; Diazoxide; Dose-Response Relationship, Drug; Drug

1976
[Treatment of refractory chronic circulatory insufficiency].
    Kardiologiia, 1976, Volume: 16, Issue:8

    Topics: Adult; Aged; Benzothiadiazines; Cardiac Glycosides; Cardiomyopathies; Chronic Disease; Coronary Dise

1976
[Treatment of resistant forms of cardiac insufficiency with a combination of diuretics].
    Kardiologiia, 1975, Volume: 15, Issue:10

    Topics: Chlorine; Circadian Rhythm; Clopamide; Coronary Disease; Diuresis; Diuretics; Drug Synergism; Drug T

1975
Role of Na-activated K channel, Na-K-Cl cotransport, and Na-K pump in [K]e changes during ischemia in rat heart.
    The American journal of physiology, 1992, Volume: 263, Issue:2 Pt 2

    Topics: Animals; Carrier Proteins; Coronary Disease; Diastole; Extracellular Space; Furosemide; Heart; Heart

1992
Prolonged diuretic administration and myocardial tolerance to ischaemia.
    Pharmacology & toxicology, 1987, Volume: 61, Issue:4

    Topics: Adenosine Triphosphate; Amiloride; Animals; Coronary Circulation; Coronary Disease; Diuretics; Elect

1987
[Differential treatment of coronary heart disease].
    Zeitschrift fur arztliche Fortbildung, 1974, Jul-01, Volume: 68, Issue:13

    Topics: Angina Pectoris; Aspirin; Cardiac Glycosides; Coronary Disease; Dipyridamole; Furosemide; Heparin; H

1974
[Use, association and contraindications of hypotensive drugs].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Jun-15, Volume: 24, Issue:12

    Topics: Antihypertensive Agents; Blood Pressure; Coronary Disease; Diuretics; Furosemide; Ganglionic Blocker

1969
Effective use of positive end expiratory pressure.
    American journal of surgery, 1974, Volume: 127, Issue:5

    Topics: Adult; Angina Pectoris; Coronary Artery Bypass; Coronary Disease; Female; Furosemide; Humans; Hypoxi

1974
[Comparison of the effectiveness and mechanism of action of the saluretic preparations triamterene and hypothiazide and their combination (triampur) in circulatory insufficiency].
    Kardiologiia, 1973, Volume: 13, Issue:4

    Topics: Acid-Base Equilibrium; Adult; Aged; Arteriosclerosis; Circadian Rhythm; Coronary Disease; Creatinine

1973
Intermittent parasystole--mechanism of protection.
    Circulation, 1973, Volume: 48, Issue:4

    Topics: Aged; Aminosalicylic Acids; Arrhythmias, Cardiac; Arteriosclerosis; Cerebrovascular Disorders; Coron

1973
Hypoxemia in acute myocardial infarction and in coronary insufficiency.
    The American journal of the medical sciences, 1973, Volume: 266, Issue:4

    Topics: Adult; Aged; Arteries; Coronary Disease; Furosemide; Humans; Hypoxia; Male; Middle Aged; Myocardial

1973
[Serum magnesium in patients with myocardial insufficiency under treatment with glycosides and furosemide].
    Klinische Wochenschrift, 1972, Mar-01, Volume: 50, Issue:5

    Topics: Adult; Colorimetry; Coronary Disease; Furosemide; Glycosides; Humans; Magnesium; Male; Potassium

1972
Exchangeable potassium in heart disease: long-term effects of potassium supplements and amiloride.
    American heart journal, 1972, Volume: 84, Issue:1

    Topics: Adult; Aged; Amiloride; Coronary Disease; Diuretics; Erythrocytes; Female; Furosemide; Heart Disease

1972
[Comparison of the effectiveness and mechanism of action of the saluretics lasix, ethacrynic acid, brinaldix and triamterene in congestive cardiac insufficiency].
    Kardiologiia, 1971, Volume: 11, Issue:9

    Topics: Adolescent; Adult; Aged; Arteriosclerosis; Coronary Disease; Diuretics; Ethacrynic Acid; Female; Fur

1971
[Modern and rational use of diuretics in cardiology].
    Cardiologia pratica, 1969, Volume: 20, Issue:6

    Topics: Coronary Disease; Diuretics; Ethacrynic Acid; Furosemide; Glucocorticoids; Heart Diseases; Humans; K

1969
[Effect of saluretics on carbohydrate metabolism].
    Kardiologiia, 1970, Volume: 10, Issue:9

    Topics: Adolescent; Adult; Carbohydrate Metabolism; Coronary Disease; Diabetes Mellitus; Diuretics; Furosemi

1970