Page last updated: 2024-10-27

furosemide and Cochlear Hearing Loss

furosemide has been researched along with Cochlear Hearing Loss in 36 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
" The present study investigated whether hearing loss contributes to dementia in the absence of aging and noise using a mouse model of severe bilateral hearing loss induced by kanamycin (1000 mg/kg) and furosemide (400 mg/kg)."4.02Sensorineural hearing loss may lead to dementia-related pathological changes in hippocampal neurons. ( Fan, C; Hu, H; Shen, Y; Wang, Q; Xiang, M; Ye, B; Zou, T, 2021)
" The risk factors associated with this impairment were higher cumulative doses of furosemide and hypocalcemia."3.79Hearing status in children with frequently relapsing and steroid resistant nephrotic syndrome. ( Batra, VV; Dubey, NK; Gupta, V; Kapoor, K; Lal, P; Saha, A; Sidhu, TS; Upadhyay, AD, 2013)
"Monitoring outcomes of neonates after HLHS surgery revealed unexpected PHL associated with hypoxia and bolus administration of furosemide."3.78Bilateral sensory permanent hearing loss after palliative hypoplastic left heart syndrome operation. ( Alton, GY; Bork, KT; Joffe, AR; Moddemann, DM; Rebeyka, IM; Robertson, CM; Ross, DB; Sauve, RS; Tawfik, GC, 2012)
" The present work reports the consequences on high- vs low-level DPOAEs of three types of cochlear impairments involving OHCs: progressive OHC degeneration of genetic origin in CD1 mice, complete cochlear ischemia in gerbils, and furosemide injection vs ischemia-reperfusion in gerbils."3.72Physiopathological significance of distortion-product otoacoustic emissions at 2f1-f2 produced by high- versus low-level stimuli. ( Avan, P; Bonfils, P; Gilain, L; Mom, T, 2003)
" Dosage or duration of aminoglycosides use did not relate to SNHL."2.72Ototoxic drugs and sensorineural hearing loss following severe neonatal respiratory failure. ( Cheung, PY; Etches, PC; Peliowski, A; Robertson, CM; Tyebkhan, JM, 2006)
"The incidence of sensorineural hearing loss (SNHL) was investigated in 68 patients who reached chronic renal failure (CRF) in childhood with the aim of identifying possible risk factors."2.68Sensorineural hearing loss in patients reaching chronic renal failure in childhood. ( Bianchi, PM; Dello Strologo, L; Mancini, ML; Rizzoni, G; Tieri, L, 1996)
"Furosemide is a very commonly used loop diuretic in current clinical practice."2.36Pathophysiology of furosemide ototoxicity. ( Rybak, LP, 1982)
"We conclude that severe sensorineural hearing loss can be induced in mice."1.39Deafness induction in mice. ( Bremer, HG; Grolman, W; Hendriksen, FG; Jansen, TT; Klis, SF; Topsakal, V, 2013)
" A dose-response study identified 200 mg/kg of furosemide as the optimal dose for disrupting the stria vascularis and opening the blood-ear barrier."1.37Co-administration of cisplatin and furosemide causes rapid and massive loss of cochlear hair cells in mice. ( Ding, D; Fu, Y; Jiang, H; Li, Y; Salvi, R, 2011)
"Furosemide did not cause an additional elevation of the threshold of the auditory nerve brainstem evoked response (ABR) over that induced by the salicylic acid injection."1.36How are the inner hair cells and auditory nerve fibers activated without the mediation of the outer hair cells and the cochlear amplifier? ( Adelman, C; Sohmer, H; Weinberger, JM, 2010)
"(41 vs 43% sensorineural hearing loss respectively)."1.29[Hearing loss resulting from purulent meningitis in the light of adjuvant dexamethasone therapy]. ( Farkas, Z; Hajdi, G; Hirschberg, J; Katona, G; Nyerges, G, 1993)
"The efficacy of L-V therapy for other sensorineural hearing loss was also evaluated."1.28The efficacy of Lasix-vitamin therapy (L-V therapy) for sudden deafness and other sensorineural hearing loss. ( Konishi, K; Nakai, Y; Yamane, H, 1991)
"Thirty-five neonates with sensorineural hearing loss (SNHL), identified by brainstem auditory evoked response (BAER), and 70 matched controls with normal BAERs were studied."1.28Neonatal sensorineural hearing loss associated with furosemide: a case-control study. ( Brown, DR; Sabo, D; Watchko, JF, 1991)
"Sensorineural hearing loss was statistically associated (1) with greater amounts of furosemide administration for longer durations and in combination with aminoglycoside antibiotics and (2) with more episodes of low pH, hypoxemia, or both, higher total bilirubin levels, and substantially lower neonatal status scores."1.28Neonatal status and hearing loss in high-risk infants. ( Eldredge, L; Salamy, A; Tooley, WH, 1989)
"Infants with the diagnosis of persistent fetal circulation were evaluated for hearing loss."1.27Hearing loss in infants with persistent fetal circulation. ( Hendricks-Muñoz, KD; Walton, JP, 1988)
" The systemic and local applications of aminoglycosides and the high dosage of furosemide were the probable ototoxic agents."1.27[Hearing loss, a complication of antibiotic therapy in severely burned patients]. ( Balogh, D; Bauer, M; Rauchegger, H; Zanon, E, 1987)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19907 (19.44)18.7374
1990's8 (22.22)18.2507
2000's6 (16.67)29.6817
2010's13 (36.11)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Behrends, W1
Ahrens, D1
Bankstahl, JP1
Esser, KH1
Paasche, G1
Lenarz, T1
Scheper, V1
Košec, A1
Kruljac, I1
Ajduk, J1
Shen, Y1
Hu, H1
Fan, C1
Wang, Q1
Zou, T1
Ye, B1
Xiang, M1
Henry, KS1
Sayles, M1
Hickox, AE1
Heinz, MG1
Kraft, S1
Hsu, C1
Brough, DE1
Staecker, H1
Jansen, TT1
Bremer, HG1
Topsakal, V1
Hendriksen, FG2
Klis, SF3
Grolman, W3
Rhee, CK1
He, P1
Jung, JY1
Ahn, JC1
Chung, PS1
Lee, MY1
Suh, MW1
Ramekers, D1
Versnel, H1
Strahl, SB1
Wang, Y1
Qiao, L1
Chen, Y1
Wen, L1
Yue, B1
Qiu, J1
Wu, S1
Żak, M1
van der Linden, CA1
Bezdjian, A1
Adelman, C1
Weinberger, JM1
Sohmer, H1
Li, Y1
Ding, D1
Jiang, H1
Fu, Y1
Salvi, R1
Pienkowski, M1
Ulfendahl, M1
Robertson, CM2
Alton, GY1
Bork, KT1
Joffe, AR1
Tawfik, GC1
Sauve, RS1
Moddemann, DM1
Ross, DB1
Rebeyka, IM1
Saha, A1
Gupta, V1
Kapoor, K1
Dubey, NK1
Lal, P1
Sidhu, TS1
Batra, VV1
Upadhyay, AD1
Avan, P1
Bonfils, P1
Gilain, L1
Mom, T1
Rais-Bahrami, K1
Majd, M1
Veszelovszky, E1
Short, BL1
Tyebkhan, JM1
Peliowski, A1
Etches, PC1
Cheung, PY1
Abbasi, AH1
Ramadan, R1
Hoffman, A1
Abassi, Z1
Humes, LE1
Minowa, Y1
Rybak, LP1
Shapiro, MJ1
Purn, JM1
Raskin, C1
Schwaber, MK1
Garraghty, PE1
Kaas, JH1
Katona, G1
Farkas, Z1
Hirschberg, J1
Hajdi, G1
Nyerges, G1
Mancini, ML1
Dello Strologo, L1
Bianchi, PM1
Tieri, L1
Rizzoni, G1
Borradori, C1
Fawer, CL1
Buclin, T1
Calame, A1
Bian, L1
Chertoff, ME1
Bates, DE1
Beaumont, SJ1
Baylis, BW1
Michel, O1
Matthias, R1
Walton, JP2
Hendricks-Munoz, K1
Konishi, K1
Nakai, Y1
Yamane, H1
Brown, DR1
Watchko, JF1
Sabo, D1
Hendricks-Muñoz, KD1
Salamy, A1
Eldredge, L1
Tooley, WH1
Bauer, M1
Zanon, E1
Balogh, D1
Rauchegger, H1

Reviews

2 reviews available for furosemide and Cochlear Hearing Loss

ArticleYear
Kidney-ear axis.
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Branchio-Oto-Renal Syndrome; Carrier Proteins; Cisplatin; Comorbidity; Diuret

2007
Pathophysiology of furosemide ototoxicity.
    The Journal of otolaryngology, 1982, Volume: 11, Issue:2

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Cats; Diuretics; Dogs; Drug Synergism; Furosemide;

1982

Trials

2 trials available for furosemide and Cochlear Hearing Loss

ArticleYear
Ototoxic drugs and sensorineural hearing loss following severe neonatal respiratory failure.
    Acta paediatrica (Oslo, Norway : 1992), 2006, Volume: 95, Issue:2

    Topics: Amikacin; Aminoglycosides; Anti-Infective Agents; Audiometry, Pure-Tone; Auditory Threshold; Diureti

2006
Sensorineural hearing loss in patients reaching chronic renal failure in childhood.
    Pediatric nephrology (Berlin, Germany), 1996, Volume: 10, Issue:1

    Topics: Acoustic Impedance Tests; Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; Audiometry, Pur

1996

Other Studies

32 other studies available for furosemide and Cochlear Hearing Loss

ArticleYear
Refinement of systemic guinea pig deafening in hearing research: Sensorineural hearing loss induced by co-administration of kanamycin and furosemide via the leg veins.
    Laboratory animals, 2023, Volume: 57, Issue:6

    Topics: Animals; Disease Models, Animal; Furosemide; Guinea Pigs; Hair Cells, Auditory; Hearing; Hearing Los

2023
Remission of Recurrent Cochlear Hydrops Associated With Bromocriptine Treatment for Macroprolactinoma.
    American journal of audiology, 2019, Sep-13, Volume: 28, Issue:3

    Topics: Adult; Audiometry, Pure-Tone; Bromocriptine; Cochlear Diseases; Diuretics; Furosemide; Glucocorticoi

2019
Sensorineural hearing loss may lead to dementia-related pathological changes in hippocampal neurons.
    Neurobiology of disease, 2021, Volume: 156

    Topics: Animals; Dementia; Female; Furosemide; Hearing Loss, Sensorineural; Hippocampus; Inflammation Mediat

2021
Divergent Auditory Nerve Encoding Deficits Between Two Common Etiologies of Sensorineural Hearing Loss.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019, 08-28, Volume: 39, Issue:35

    Topics: Animals; Auditory Perception; Auditory Threshold; Chinchilla; Cochlear Nerve; Disease Models, Animal

2019
Atoh1 induces auditory hair cell recovery in mice after ototoxic injury.
    The Laryngoscope, 2013, Volume: 123, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Basic Helix-Loop-Helix Transcription Factors; Cochlear Diseases; Diu

2013
Deafness induction in mice.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2013, Volume: 34, Issue:8

    Topics: Animals; Disease Models, Animal; Diuretics; Furosemide; Hair Cells, Auditory; Hearing Loss, Sensorin

2013
Effect of low-level laser treatment on cochlea hair-cell recovery after ototoxic hearing loss.
    Journal of biomedical optics, 2013, Volume: 18, Issue:12

    Topics: Animals; Ear Canal; Furosemide; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Lase

2013
Recovery characteristics of the electrically stimulated auditory nerve in deafened guinea pigs: relation to neuronal status.
    Hearing research, 2015, Volume: 321

    Topics: Animals; Auditory Perception; Cochlear Implantation; Cochlear Nerve; Disease Models, Animal; Electri

2015
Establishment of a model of cochlear lesions in rats to study potential gene therapy for sensorineural hearing loss.
    International journal of pediatric otorhinolaryngology, 2015, Volume: 79, Issue:12

    Topics: Adenoviridae; Animals; Axons; Cell Death; Disease Models, Animal; Furosemide; Gene Transfer Techniqu

2015
Scar formation in mice deafened with kanamycin and furosemide.
    Microscopy research and technique, 2016, Volume: 79, Issue:8

    Topics: Animals; Disease Models, Animal; Furosemide; Hair Cells, Auditory; Hearing Loss, Sensorineural; Kana

2016
How are the inner hair cells and auditory nerve fibers activated without the mediation of the outer hair cells and the cochlear amplifier?
    Journal of basic and clinical physiology and pharmacology, 2010, Volume: 21, Issue:3

    Topics: Animals; Anion Transport Proteins; Cochlear Nerve; Disease Models, Animal; Evoked Potentials, Audito

2010
Co-administration of cisplatin and furosemide causes rapid and massive loss of cochlear hair cells in mice.
    Neurotoxicity research, 2011, Volume: 20, Issue:4

    Topics: Animals; Antineoplastic Agents; Auditory Threshold; Cell Death; Cisplatin; Disease Models, Animal; D

2011
Differential effects of salicylate, quinine, and furosemide on Guinea pig inner and outer hair cell function revealed by the input-output relation of the auditory brainstem response.
    Journal of the American Academy of Audiology, 2011, Volume: 22, Issue:2

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal;

2011
Bilateral sensory permanent hearing loss after palliative hypoplastic left heart syndrome operation.
    The Annals of thoracic surgery, 2012, Volume: 93, Issue:4

    Topics: Audiometry; Cardiac Surgical Procedures; Child, Preschool; Diuretics; Furosemide; Hearing Loss, Sens

2012
Hearing status in children with frequently relapsing and steroid resistant nephrotic syndrome.
    Pediatric nephrology (Berlin, Germany), 2013, Volume: 28, Issue:3

    Topics: Adolescent; Audiometry, Pure-Tone; Auditory Threshold; Biomarkers; Bone Conduction; Calcium; Case-Co

2013
Physiopathological significance of distortion-product otoacoustic emissions at 2f1-f2 produced by high- versus low-level stimuli.
    The Journal of the Acoustical Society of America, 2003, Volume: 113, Issue:1

    Topics: Acoustic Stimulation; Animals; Auditory Threshold; Brain Stem; Cochlea; Deafness; Disease Models, An

2003
Use of furosemide and hearing loss in neonatal intensive care survivors.
    American journal of perinatology, 2004, Volume: 21, Issue:6

    Topics: Auditory Threshold; Brain Stem; Deafness; District of Columbia; Diuretics; Female; Furosemide; Heari

2004
Noise-induced hearing loss as influenced by other agents and by some physical characteristics of the individual.
    The Journal of the Acoustical Society of America, 1984, Volume: 76, Issue:5

    Topics: Acoustic Stimulation; Age Factors; Animals; Ethacrynic Acid; Eye Color; Furosemide; Hearing Loss, No

1984
[Sensorineural hearing impairment by combined administration of aminoglycoside drugs, loop diuretics and an anticancer drug (cisplatin)--an experimental study].
    Nihon Jibiinkoka Gakkai kaiho, 1984, Volume: 87, Issue:2

    Topics: Animals; Cisplatin; Drug Therapy, Combination; Furosemide; Guinea Pigs; Hearing Loss, Sensorineural;

1984
A study of the effects of cardiopulmonary bypass surgery on auditory function.
    The Laryngoscope, 1981, Volume: 91, Issue:12

    Topics: Audiometry, Pure-Tone; Cardiopulmonary Bypass; Female; Furosemide; Hearing Loss, Sensorineural; Huma

1981
Neuroplasticity of the adult primate auditory cortex following cochlear hearing loss.
    The American journal of otology, 1993, Volume: 14, Issue:3

    Topics: Animals; Audiometry, Pure-Tone; Auditory Cortex; Ear, Inner; Evoked Potentials, Auditory, Brain Stem

1993
[Hearing loss resulting from purulent meningitis in the light of adjuvant dexamethasone therapy].
    Orvosi hetilap, 1993, Jan-31, Volume: 134, Issue:5

    Topics: Chemotherapy, Adjuvant; Child, Preschool; Dexamethasone; Female; Furosemide; Hearing Loss, Sensorine

1993
Risk factors of sensorineural hearing loss in preterm infants.
    Biology of the neonate, 1997, Volume: 71, Issue:1

    Topics: Aminoglycosides; Evoked Potentials, Auditory, Brain Stem; Furosemide; Gestational Age; Hearing Loss,

1997
Distinguishing cochlear pathophysiology in 4-aminopyridine and furosemide treated ears using a nonlinear systems identification technique.
    The Journal of the Acoustical Society of America, 2001, Volume: 109, Issue:2

    Topics: 4-Aminopyridine; Animals; Auditory Threshold; Cochlea; Diuretics; Furosemide; Gerbillinae; Hair Cell

2001
Ototoxicity induced by gentamicin and furosemide.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:3

    Topics: Anti-Bacterial Agents; Community-Acquired Infections; Diuretics; Drug Synergism; Female; Furosemide;

2002
Effects of prostaglandin E2 on the fluctuating hearing loss in Ménière's disease.
    Auris, nasus, larynx, 1992, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Audiometry, Pure-Tone; Auditory Threshold; Dinoprostone; Female; Fur

1992
Profile and stability of sensorineural hearing loss in persistent pulmonary hypertension of the newborn.
    Journal of speech and hearing research, 1991, Volume: 34, Issue:6

    Topics: Amikacin; Analysis of Variance; Follow-Up Studies; Furosemide; Hearing Loss, Sensorineural; Humans;

1991
The efficacy of Lasix-vitamin therapy (L-V therapy) for sudden deafness and other sensorineural hearing loss.
    Acta oto-laryngologica. Supplementum, 1991, Volume: 486

    Topics: Adult; Aged; Drug Combinations; Female; Furosemide; Hearing Loss, Sensorineural; Hearing Loss, Sudde

1991
Neonatal sensorineural hearing loss associated with furosemide: a case-control study.
    Developmental medicine and child neurology, 1991, Volume: 33, Issue:9

    Topics: Auditory Threshold; Brain Stem; Child, Preschool; Deafness; Evoked Potentials, Auditory, Brain Stem;

1991
Hearing loss in infants with persistent fetal circulation.
    Pediatrics, 1988, Volume: 81, Issue:5

    Topics: Developmental Disabilities; Furosemide; Hearing Aids; Hearing Loss, Sensorineural; Humans; Infant; I

1988
Neonatal status and hearing loss in high-risk infants.
    The Journal of pediatrics, 1989, Volume: 114, Issue:5

    Topics: Aminoglycosides; Anti-Bacterial Agents; Audiometry, Evoked Response; Bilirubin; Furosemide; Hearing

1989
[Hearing loss, a complication of antibiotic therapy in severely burned patients].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 1987, Volume: 19, Issue:3

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Burns; Creatinine; Female; Furosemide; Hearing Loss,

1987