Page last updated: 2024-10-27

furosemide and Cardiomegaly

furosemide has been researched along with Cardiomegaly in 34 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"The open, long-term antihypertensive, hemodynamic and metabolic effects of betaxolol in combination with furosemide and minoxidil were investigated on 30 male patients with moderate to severe essential hypertension."9.07Cardiac changes from beta-blocker, diuretic and minoxidil combination in hypertension. ( Berlin, L; Chrysant, C; Chrysant, SG; Sadeghi, M, 1991)
"The effect of long-term timolol treatment on heart size after myocardial infarction was evaluated by X-ray in a double-blind study including 241 patients (placebo 126, timolol 115)."9.05Changes in heart size during long-term timolol treatment after myocardial infarction. ( Abrahamsen, AM; Barstad, S; Gundersen, T; Rønnevik, P; Traetteberg, K; von Brandis, C, 1984)
"Minoxidil has been administered to 16 patients with severe hypertension and renal failure."9.04Minoxidil in severe hypertension. ( Mäkelä, M; Oka, M, 1978)
"Eleven patients with congestive heart failure class II-IV (NYHA) caused by ischemic heart disease were studied before and three months after adding enalapril to their treatment with furosemide."7.68Cardiac remodelling and myocardial contractility in patients with congestive heart failure treated with furosemide and enalapril. ( Bann, J; Baur, LH; Bruschke, AV; Buis, B; Manger Cats, V; Schipperheyn, JJ; van der Laarse, A; van der Wall, EE; van Dijk, AD, 1991)
"Hypertension is a major risk factor for atherogenesis and heart hypertrophy, both of which are associated with specific morphological and functional changes of the myocardium."5.43Furosemide modifies heart hypertrophy and glycosaminoglycan myocardium content in a rat model of neurogenic hypertension. ( Karakiulakis, G; Kouvelas, D; Manthou, ME; Papakonstantinou, E; Pourzitaki, C; Tsaousi, G, 2016)
"The open, long-term antihypertensive, hemodynamic and metabolic effects of betaxolol in combination with furosemide and minoxidil were investigated on 30 male patients with moderate to severe essential hypertension."5.07Cardiac changes from beta-blocker, diuretic and minoxidil combination in hypertension. ( Berlin, L; Chrysant, C; Chrysant, SG; Sadeghi, M, 1991)
"The effect of long-term timolol treatment on heart size after myocardial infarction was evaluated by X-ray in a double-blind study including 241 patients (placebo 126, timolol 115)."5.05Changes in heart size during long-term timolol treatment after myocardial infarction. ( Abrahamsen, AM; Barstad, S; Gundersen, T; Rønnevik, P; Traetteberg, K; von Brandis, C, 1984)
"Minoxidil has been administered to 16 patients with severe hypertension and renal failure."5.04Minoxidil in severe hypertension. ( Mäkelä, M; Oka, M, 1978)
"Eleven patients with congestive heart failure class II-IV (NYHA) caused by ischemic heart disease were studied before and three months after adding enalapril to their treatment with furosemide."3.68Cardiac remodelling and myocardial contractility in patients with congestive heart failure treated with furosemide and enalapril. ( Bann, J; Baur, LH; Bruschke, AV; Buis, B; Manger Cats, V; Schipperheyn, JJ; van der Laarse, A; van der Wall, EE; van Dijk, AD, 1991)
"During 12-week hydrochlorothiazide treatment 16 men suffering from uncomplicated essential hypertension were examined."3.66[Hemodynamic mechanism of the hypotensive action of diuretics and their effect on myocardial hypertrophy in the process of long-term treatment of hypertension]. ( D'iakonova, EG; Iurenev, AP, 1982)
"On echocardiography, the left ventricular hypertrophy, identified earlier, shoed partial regression."1.91Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism. ( Chae, Y; Kang, BT; Kim, H; Koo, Y; Lee, D; Lee, H; Park, J; Yang, MP; Yun, T, 2023)
"Lutembacher syndrome is characterized by a congenital ostium secundum atrial septal defect and an acquired mitral valve stenosis."1.48Lutembacher syndrome with mitral valve calcification in a 31-year old male. ( Adam, AM; Ali Mallick, MS; Godil, A; Khan, F; Makhdoom, IM; Rizvi, AH, 2018)
"Hypertension is a major risk factor for atherogenesis and heart hypertrophy, both of which are associated with specific morphological and functional changes of the myocardium."1.43Furosemide modifies heart hypertrophy and glycosaminoglycan myocardium content in a rat model of neurogenic hypertension. ( Karakiulakis, G; Kouvelas, D; Manthou, ME; Papakonstantinou, E; Pourzitaki, C; Tsaousi, G, 2016)
"Rosiglitazone treatment induced volume expansion and CH in wild-type and PPARγ heterozygous knockout (Pparg(+/-)) mice, but not in mice defective for ligand binding (Pparg(P465L/+))."1.40Diuretics prevent thiazolidinedione-induced cardiac hypertrophy without compromising insulin-sensitizing effects in mice. ( Chang, CS; Chen, JY; Ho, LC; Maeda, N; Pandya, K; Sung, JM; Tsai, PJ; Tsai, YS, 2014)
"Renal function and salt and water turnover were studied in SHR during acute and chronic administration of felodipine, which is an efficient antihypertensive vasodilating Ca2+ antagonist."1.27Renal and cardiovascular effects of acute and chronic administration of felodipine to SHR. ( Di Bona, GF; Ljung, B; Nordlander, M; Thorén, P; Yao, T, 1985)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199017 (50.00)18.7374
1990's9 (26.47)18.2507
2000's2 (5.88)29.6817
2010's5 (14.71)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Lee, H1
Lee, D1
Park, J1
Yun, T1
Koo, Y1
Chae, Y1
Kang, BT1
Yang, MP1
Kim, H1
Adam, AM1
Godil, A1
Ali Mallick, MS1
Khan, F1
Rizvi, AH1
Makhdoom, IM1
Grzeskowiak, MZ1
Ahmed, N1
Chang, CS1
Tsai, PJ1
Sung, JM1
Chen, JY1
Ho, LC1
Pandya, K1
Maeda, N2
Tsai, YS1
Pourzitaki, C1
Tsaousi, G1
Manthou, ME1
Karakiulakis, G1
Kouvelas, D1
Papakonstantinou, E1
Kujal, P1
Chábová, VČ1
Vernerová, Z1
Walkowska, A1
Kompanowska-Jezierska, E1
Sadowski, J1
Vaňourková, Z1
Husková, Z1
Opočenský, M1
Skaroupková, P1
Schejbalová, S1
Kramer, HJ1
Rakušan, D1
Malý, J1
Netuka, I1
Vaněčková, I1
Kopkan, L1
Cervenka, L1
Sohn, IS1
Jin, ES1
Cho, JM1
Kim, CJ1
Bae, JH1
Moon, JY1
Lee, SH1
Kim, MJ1
D'iakonova, EG1
Iurenev, AP1
Gundersen, T1
Traetteberg, K1
Rønnevik, P1
von Brandis, C1
Barstad, S1
Abrahamsen, AM1
Bart, BIa1
Pashkova, TL1
Stepanov, NG1
Orlova, TV1
Kalmanova, EN1
DePace, NL1
Burke, W1
Kotler, MN1
Glazier, EE1
Kim, S1
Hamaguchi, A1
Shinkawa, T1
Kato, Y1
Tsuchiya, N1
Miura, K1
Ohta, K1
Iwao, H1
Nakagawa, C1
Sakaguchi, Y1
Nakajima, T1
Kawamoto, A1
Uemura, S1
Fujimoto, S1
Hashimoto, T1
Dohi, K1
Shirai, T1
Gavaghan, BJ1
Kittleson, MD1
McAloose, D1
Knowles, JW1
Esposito, G1
Mao, L1
Hagaman, JR1
Fox, JE1
Smithies, O1
Rockman, HA1
Oka, M1
Mäkelä, M1
Falase, AO1
Markenson, JA1
Sherman, RL1
Brown, G1
O'Leary, M1
Douglas, I1
Herkes, R1
Chrysant, SG1
Chrysant, C1
Sadeghi, M1
Berlin, L1
Baur, LH1
Schipperheyn, JJ1
Bann, J1
van der Laarse, A1
van der Wall, EE1
van Dijk, AD1
Buis, B1
Manger Cats, V1
Bruschke, AV1
Angermann, CE1
Spes, CH1
Willems, S1
Dominiak, P1
Kemkes, BM1
Theisen, K1
Oviasu, E1
Freeman, O1
Sharpe, N1
Murphy, J1
Smith, H1
Hannan, S1
Hori, K1
Mirsky, I1
Fouad-Tarazi, FM1
Nordlander, M1
Di Bona, GF1
Ljung, B1
Yao, T1
Thorén, P1
Perlman, JM1
Moore, V1
Siegel, MJ1
Dawson, J1
Grassi, G1
Giannattasio, C1
Cléroux, J1
Cuspidi, C1
Sampieri, L1
Bolla, GB1
Mancia, G1
Modai, D1
Cohen, N1
Weissgarten, J1
Segal, B1
Pik, A1
Gruskin, AB1
Budow, J1
Natarajan, P1
Kroop, IG1
Steeg, CN1
Ellis, K1
Gersony, WM1
Arnold, K1
Matthews, AW1
Griffiths, ID1

Trials

4 trials available for furosemide and Cardiomegaly

ArticleYear
Changes in heart size during long-term timolol treatment after myocardial infarction.
    Acta medica Scandinavica, 1984, Volume: 215, Issue:1

    Topics: Adult; Aged; Cardiomegaly; Digitalis Glycosides; Double-Blind Method; Female; Follow-Up Studies; Fur

1984
Minoxidil in severe hypertension.
    Acta medica Scandinavica, 1978, Volume: 203, Issue:1-2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cardiac Output; Cardiomegaly; Clinical Trials as Top

1978
Cardiac changes from beta-blocker, diuretic and minoxidil combination in hypertension.
    Cardiology, 1991, Volume: 78, Issue:1

    Topics: Betaxolol; Cardiomegaly; Drug Therapy, Combination; Edema; Furosemide; Humans; Hypertension; Male; M

1991
Preventive treatment of asymptomatic left ventricular dysfunction following myocardial infarction.
    European heart journal, 1990, Volume: 11 Suppl B

    Topics: Adult; Aged; Blood Pressure; Captopril; Cardiac Volume; Cardiomegaly; Double-Blind Method; Female; F

1990

Other Studies

30 other studies available for furosemide and Cardiomegaly

ArticleYear
Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism.
    Acta veterinaria Hungarica, 2023, 10-17, Volume: 71, Issue:2

    Topics: Animals; Cardiomegaly; Cardiomyopathy, Hypertrophic; Cat Diseases; Cats; Furosemide; Heart Failure;

2023
Lutembacher syndrome with mitral valve calcification in a 31-year old male.
    JPMA. The Journal of the Pakistan Medical Association, 2018, Volume: 68, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Amiloride; Anticoagulants; Atrial Fibrillation; Bundle-Branch Bl

2018
Case of giant left atrium from congestive heart failure.
    BMJ case reports, 2018, Jun-27, Volume: 2018

    Topics: Aged; Atrial Fibrillation; Cardiac Output, Low; Cardiomegaly; Echocardiography; Female; Furosemide;

2018
Diuretics prevent thiazolidinedione-induced cardiac hypertrophy without compromising insulin-sensitizing effects in mice.
    The American journal of pathology, 2014, Volume: 184, Issue:2

    Topics: Animals; Cardiac Volume; Cardiomegaly; Diuretics; Extracellular Signal-Regulated MAP Kinases; Furose

2014
Furosemide modifies heart hypertrophy and glycosaminoglycan myocardium content in a rat model of neurogenic hypertension.
    European journal of pharmacology, 2016, Aug-05, Volume: 784

    Topics: Animals; Aorta; Cardiomegaly; Denervation; Disease Models, Animal; Epinephrine; Furosemide; Glycosam

2016
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:12

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2010
Bloodletting-induced cardiomyopathy: reversible cardiac hypertrophy in severe chronic anaemia from long-term bloodletting with cupping.
    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2008, Volume: 9, Issue:5

    Topics: Aged; Anemia, Iron-Deficiency; Angiotensin-Converting Enzyme Inhibitors; Cardiomegaly; Chronic Disea

2008
[Hemodynamic mechanism of the hypotensive action of diuretics and their effect on myocardial hypertrophy in the process of long-term treatment of hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1982, Volume: 5, Issue:1

    Topics: Adult; Antihypertensive Agents; Cardiomegaly; Diuretics; Drug Evaluation; Furosemide; Heart; Hemodyn

1982
[Dilatation (congestive) cardiomyopathy: clinical aspects, diagnosis and treatment].
    Kardiologiia, 1984, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Cardiomegaly; Cardiomyopathy, Dilated; Coronary Disease; Diagnosis, Differential;

1984
An unusual case of Bjork-Shiley mitral valve dysfunction corrected nonsurgically.
    Chest, 1981, Volume: 80, Issue:4

    Topics: Aspirin; Cardiomegaly; Dipyridamole; Echocardiography; Female; Furosemide; Heart Murmurs; Heart Valv

1981
Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Diuretics; Electrolytes; Furosemide; G

1996
A case of eosinophilic myocarditis complicated by Kimura's disease (eosinophilic hyperplastic lymphogranuloma) and erythroderma.
    Japanese circulation journal, 1999, Volume: 63, Issue:2

    Topics: Angiolymphoid Hyperplasia with Eosinophilia; Anti-Inflammatory Agents; Biopsy; Cardiomegaly; Dermati

1999
Persistent atrial standstill in a cat.
    Australian veterinary journal, 1999, Volume: 77, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arrhythmias, Cardiac; Asp

1999
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice.
    The Journal of clinical investigation, 2001, Volume: 107, Issue:8

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Enalapril; Furosemide; Guanylate Cyc

2001
Cardiomegaly of unknown origin among Nigerian adults: role of hypertension in its aetiology.
    British heart journal, 1977, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Alcoholic Beverages; Benzothiadiazines; Blood Pressure; Cardiomegaly; Cardi

1977
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:10

    Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide

1979
Perioperative management of a case of severe peripartum cardiomyopathy.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:1

    Topics: Adult; Captopril; Cardiomegaly; Cesarean Section; Critical Care; Digoxin; Dobutamine; Dopamine; Fema

1992
Cardiac remodelling and myocardial contractility in patients with congestive heart failure treated with furosemide and enalapril.
    Basic research in cardiology, 1991, Volume: 86 Suppl 1

    Topics: Aged; Angiotensin II; Cardiomegaly; Drug Therapy, Combination; Enalapril; Furosemide; Heart Failure;

1991
Regression of left ventricular hypertrophy in hypertensive heart transplant recipients treated with enalapril, furosemide, and verapamil.
    Circulation, 1991, Volume: 84, Issue:2

    Topics: Adult; Cardiomegaly; Echocardiography; Electrocardiography; Enalapril; Female; Furosemide; Heart Tra

1991
Marfan's syndrome: a case report.
    East African medical journal, 1991, Volume: 68, Issue:4

    Topics: Adult; Anthropometry; Cardiomegaly; Digoxin; Furosemide; Humans; Male; Marfan Syndrome

1991
Effects of chronic sodium depletion on function of isolated normal and hypertensive hypertrophied rat heart.
    Cardiovascular research, 1989, Volume: 23, Issue:5

    Topics: Animals; Cardiomegaly; Combined Modality Therapy; Diet, Sodium-Restricted; Elasticity; Furosemide; H

1989
Renal and cardiovascular effects of acute and chronic administration of felodipine to SHR.
    European journal of pharmacology, 1985, Jul-11, Volume: 113, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Felodipine; Furosemide; Heart Rate;

1985
Is chloride depletion an important contributing cause of death in infants with bronchopulmonary dysplasia?
    Pediatrics, 1986, Volume: 77, Issue:2

    Topics: Acid-Base Imbalance; Body Weight; Bronchopulmonary Dysplasia; Cardiomegaly; Chlorides; Furosemide; H

1986
Cardiopulmonary reflex before and after regression of left ventricular hypertrophy in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 12, Issue:3

    Topics: Adult; Arteries; Blood Pressure; Cardiomegaly; Central Venous Pressure; Cold Temperature; Female; Fu

1988
Symptomatic renal artery stenosis superimposed on chronic glomerulonephritis.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:4

    Topics: Antihypertensive Agents; Cardiomegaly; Chlorthalidone; Chronic Disease; Creatinine; Furosemide; Glom

1985
The adolescent with essential hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1985, Volume: 6, Issue:2

    Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Diet, Sodium-Restricted; Furosemi

1985
Pulmonary edema following direct current cardioversion for atrial arrhythmias.
    JAMA, 1971, Dec-20, Volume: 218, Issue:12

    Topics: Aged; Atrial Fibrillation; Cardiomegaly; Electric Countershock; Female; Furosemide; Heart Atria; Hea

1971
Total anomalous pulmonary venous drainage with ventricular septal defect.
    American heart journal, 1973, Volume: 86, Issue:3

    Topics: Angiocardiography; Cardiac Catheterization; Cardiomegaly; Digoxin; Electrocardiography; Extracorpore

1973
Typhoid fever with myocarditis.
    The American journal of tropical medicine and hygiene, 1974, Volume: 23, Issue:2

    Topics: Adult; Ampicillin; Cardiomegaly; Chloramphenicol; Digitalis Glycosides; Electrocardiography; Female;

1974
Post-vaccinial pericarditis and myocarditis.
    British heart journal, 1974, Volume: 36, Issue:10

    Topics: Adult; Body Temperature; Cardiomegaly; Digoxin; Electrocardiography; Furosemide; Humans; Hydrocortis

1974