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furosemide and Bronchial Hyperreactivity

furosemide has been researched along with Bronchial Hyperreactivity in 8 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research Excerpts

ExcerptRelevanceReference
"We determined whether chronic administration of furosemide aerosol would be beneficial for the treatment of asthma."9.08Effect of acute and chronic inhaled furosemide on bronchial hyperresponsiveness in mild asthma. ( Aikman, S; Barnes, PJ; Chung, KF; O'Connor, BJ; Worsdell, M; Yates, DH; Yilmaz, G, 1995)
" To investigate whether prostaglandin production could also modulate the bronchial antireactive activity of this diuretic drug, we investigated the effect of inhaled lysine acetylsalicylate (162 mg) and of furosemide (18 mg), alone and in combination, on the bronchial obstructive response to ultrasonically nebulized water in asthmatic patients."9.07Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate. ( Berni, F; Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1993)
"This study sought to investigate the cellular profile of NKCC1 expression in the lung and examine the effects of furosemide on several outcome measurements in a mouse model of allergic asthma."7.77Effects of furosemide on allergic asthmatic responses in mice. ( Ellis, R; Feng, M; Inman, MD; Lu, WY; Wang, S; Wattie, J; Xiang, YY, 2011)
"We studied the effects of inhaled furosemide (40 mg) on bronchial responsiveness to acetylcholine (ACh) in patients with chronic congestive heart failure who had been premedicated with indomethacin (75 mg/day) for five days."7.69[Effects of inhaled furosemide after indomethacin premedication on bronchial hyperresponsiveness in patients with chronic congestive heart failure]. ( Ishizaki, T; Kanamori, K; Mifune, J; Miyabo, S; Nakai, T; Saitoh, Y; Sakai, T; Sasaki, F, 1994)
"We studied the effects of inhaled and intravenous furosemide (40 mg) on bronchial responsiveness to acetylcholine (ACh) in patients with chronic congestive heart failure."7.68[Effects of inhaled and intravenous furosemide on bronchial hyperresponsiveness in patients with chronic congestive heart failure]. ( Fujimura, M; Hifumi, S; Ishizaki, T; Mifune, J; Miyabo, S; Nakai, T; Sakai, T; Sasaki, F; Takahashi, H, 1992)
"We determined whether chronic administration of furosemide aerosol would be beneficial for the treatment of asthma."5.08Effect of acute and chronic inhaled furosemide on bronchial hyperresponsiveness in mild asthma. ( Aikman, S; Barnes, PJ; Chung, KF; O'Connor, BJ; Worsdell, M; Yates, DH; Yilmaz, G, 1995)
" To investigate whether prostaglandin production could also modulate the bronchial antireactive activity of this diuretic drug, we investigated the effect of inhaled lysine acetylsalicylate (162 mg) and of furosemide (18 mg), alone and in combination, on the bronchial obstructive response to ultrasonically nebulized water in asthmatic patients."5.07Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate. ( Berni, F; Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1993)
"This study sought to investigate the cellular profile of NKCC1 expression in the lung and examine the effects of furosemide on several outcome measurements in a mouse model of allergic asthma."3.77Effects of furosemide on allergic asthmatic responses in mice. ( Ellis, R; Feng, M; Inman, MD; Lu, WY; Wang, S; Wattie, J; Xiang, YY, 2011)
" Airway responsiveness in patients with mild asthma correlated with the furosemide-insensitive influx of sodium into peripheral leukocytes stimulated by autologous serum, but there was no relation between this influx and 24-h urinary sodium excretion."3.69Dietary sodium intake, airway responsiveness, and cellular sodium transport. ( Barton, JR; Burney, PG; Poston, L; Tribe, RM, 1994)
"We studied the effects of inhaled furosemide (40 mg) on bronchial responsiveness to acetylcholine (ACh) in patients with chronic congestive heart failure who had been premedicated with indomethacin (75 mg/day) for five days."3.69[Effects of inhaled furosemide after indomethacin premedication on bronchial hyperresponsiveness in patients with chronic congestive heart failure]. ( Ishizaki, T; Kanamori, K; Mifune, J; Miyabo, S; Nakai, T; Saitoh, Y; Sakai, T; Sasaki, F, 1994)
"We studied the effects of inhaled and intravenous furosemide (40 mg) on bronchial responsiveness to acetylcholine (ACh) in patients with chronic congestive heart failure."3.68[Effects of inhaled and intravenous furosemide on bronchial hyperresponsiveness in patients with chronic congestive heart failure]. ( Fujimura, M; Hifumi, S; Ishizaki, T; Mifune, J; Miyabo, S; Nakai, T; Sakai, T; Sasaki, F; Takahashi, H, 1992)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, S1
Xiang, YY1
Ellis, R1
Wattie, J1
Feng, M1
Inman, MD1
Lu, WY1
Polosa, R2
Rajakulasingam, K1
Prosperini, G2
Magrì, S2
Mastruzzo, C2
Holgate, ST1
Tribe, RM1
Barton, JR1
Poston, L1
Burney, PG1
Saitoh, Y1
Sasaki, F2
Sakai, T2
Ishizaki, T2
Nakai, T2
Miyabo, S2
Kanamori, K1
Mifune, J2
Bianco, S1
Vaghi, A1
Pieroni, MG1
Robuschi, M1
Refini, RM1
Berni, F1
Sestini, P1
Yates, DH1
O'Connor, BJ1
Yilmaz, G1
Aikman, S1
Worsdell, M1
Barnes, PJ1
Chung, KF1
Crimi, N1
Ciamarra, I1
Takahashi, H1
Hifumi, S1
Fujimura, M1

Trials

4 trials available for furosemide and Bronchial Hyperreactivity

ArticleYear
Inhaled loop diuretics and basal airway responsiveness in man: evidence of a role for cyclo-oxygenase products.
    The European respiratory journal, 1995, Volume: 8, Issue:4

    Topics: Administration, Inhalation; Administration, Oral; Adult; Aerosols; Asthma; Bronchial Hyperreactivity

1995
Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate.
    Allergy, 1993, Volume: 48, Issue:8

    Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast

1993
Effect of acute and chronic inhaled furosemide on bronchial hyperresponsiveness in mild asthma.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:6 Pt 1

    Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; B

1995
Changes in neurokinin A (NKA) airway responsiveness with inhaled frusemide in asthma.
    Thorax, 1997, Volume: 52, Issue:9

    Topics: Administration, Inhalation; Adult; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Bronchia

1997

Other Studies

4 other studies available for furosemide and Bronchial Hyperreactivity

ArticleYear
Effects of furosemide on allergic asthmatic responses in mice.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:10

    Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage

2011
Dietary sodium intake, airway responsiveness, and cellular sodium transport.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:6

    Topics: Adolescent; Adult; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Te

1994
[Effects of inhaled furosemide after indomethacin premedication on bronchial hyperresponsiveness in patients with chronic congestive heart failure].
    Nihon Kyobu Shikkan Gakkai zasshi, 1994, Volume: 32, Issue:5

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Bronchial Hyperreactivity; Chronic Disease; Fem

1994
[Effects of inhaled and intravenous furosemide on bronchial hyperresponsiveness in patients with chronic congestive heart failure].
    Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:7

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Bronchial Hyperreactivity; Chronic Disea

1992