Page last updated: 2024-10-27

furosemide and Aging

furosemide has been researched along with Aging in 74 studies

Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Furosemide (F)-induced nephrocalcinosis (NC) has been traditionally described in low birth weight premature infants."7.70Effect of age on furosemide-induced nephrocalcinosis in the rat. ( Alon, MM; Alon, US; Nichols, MA; Osorio, AV, 1998)
"Furosemide (F)-induced nephrocalcinosis (NC) has been traditionally described in low birth weight premature infants."3.70Effect of age on furosemide-induced nephrocalcinosis in the rat. ( Alon, MM; Alon, US; Nichols, MA; Osorio, AV, 1998)
"Measurements of dopamine (DA) and its metabolites in plasma (DA sulfate) and urine (homovanillic acid) as well as its urinary response to furosemide revealed two distinct patterns: a hyperdopaminergic state in borderline essential hypertension (EH) and a renal DA deficiency in stable EH."3.68Peripheral dopamine in essential hypertension. An early defense against hypertension failing during its progression? ( Kuchel, O, 1990)
"The effect of age on the levels of active and trypsin-activatable inactive plasma renin was examined in 41 normal subjects and 54 patients with essential hypertension, during recumbency and after stimulation with furosemide and ambulation."3.66Effect of age on active and inactive plasma renin in normal subjects and in patients with essential hypertension. ( Hata, T; Higaki, J; Iwanaga, K; Kumahara, Y; Maruyama, A; Mikami, H; Murakami, K; Naka, T; Nakamaru, M; Ogihara, T, 1981)
"The effect of age on active and cryoactivatable inactive plasma renin levels was examined in 58 normal subjects and 58 patients with essential hypertension during recumbency and after stimulation with furosemide and ambulation."3.66The effect of age on active and cryoactivatable inactive plasma renin in normal subjects and patients with essential hypertension. ( Hata, T; Iwanaga, K; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Nakamaru, M; Ogihara, T, 1981)
"SIADH is underdiagnosed, and hospitalization often worsens the clinical situation, due to an iatrogenic excess in the use of oral and i."2.46[Current considerations in syndrome of inappropriate secretion of antidiuretic hormone/syndrome of inappropriate antidiuresis]. ( Runkle de la Vega, I; Velasco Cano, MV, 2010)
"Treatment with furosemide or HCTZ did not have relevant effects on measured parameters."1.43The Effects of Early Postnatal Diuretics Treatment on Kidney Development and Long-Term Kidney Function in Wistar Rats. ( Bueters, RR; Florquin, S; Jeronimus-Klaasen, A; Maicas, N; Schreuder, MF; van den Heuvel, LP, 2016)
" Consequently, a knowledge gap exists with regard to pharmacokinetic (PK) and pharmacodynamic (PD) responses in elderly subjects, leaving the safety and efficacy of medicines for this population unclear."1.43Development of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly Individuals. ( Eissing, T; Jaehde, U; Krauss, M; Meyer, M; Schlender, JF; Thelen, K; Willmann, S, 2016)
"Primary aldosteronism (PA) is common in young or middle-aged hypertensive patients, but PA among the elderly has recently become more common."1.40The influence of aging on the diagnosis of primary aldosteronism. ( Hongyo, K; Ito, N; Kamide, K; Kawai, T; Nakama, C; Onishi, M; Rakugi, H; Sugimoto, K; Takeya, Y; Yamamoto, K, 2014)
"The cause for the hypertension is unknown."1.35Prenatal programming of rat thick ascending limb chloride transport by low-protein diet and dexamethasone. ( Baum, M; Dagan, A; Dwarakanath, V; Gattineni, J; Habib, S, 2009)
"Idiopathic nocturia is due to daytime volume expansion associated with the upright position."1.35Aging, circadian weight change, and nocturia. ( Kaye, M, 2008)
"Ibuprofen did not inhibit the action of furosemide to improve medullary pO2 in younger subjects."1.31Effects of furosemide on medullary oxygenation in younger and older subjects. ( Epstein, FH; Prasad, P, 2000)
" The changes in the ETK (erythrocyte transketolase activity in whole blood) and a-ETK (ETK activity coefficient) during the hospital stay correlated with the cumulative dosage of furosemide adjusted for the duration of the therapy (r = 0."1.31Diuretic use: a risk for subclinical thiamine deficiency in elderly patients. ( Haller, J; Hany, A; Suter, PM; Vetter, W, 2000)
"Furosemide (30 mg/kg) was given orally at 12:00 h (day trial) or 00:00 h (night trial) to rats at 3 months of age, and urine was collected for 8 h after dosage."1.29Decrease in the time-dependent difference in urinary excretion of furosemide with age. ( Ebihara, A; Fujimura, A; Sudoh, T, 1994)
"2 years, 1,594 (31%) had at least one interacting drug combination according to the Swedish National Formulary."1.29Potential drug--drug interactions in 5,125 mostly elderly out-patients in Gothenburg, Sweden. ( Bergendal, L; Friberg, A; Schaffrath, A, 1995)
"Furosemide was administered as either an i."1.28Pharmacokinetics and dynamics of furosemide in the newborn piglet. ( Chapron, DJ; Kramer, PA; Miceli, JJ; Raye, JR; Rosenkrantz, TS, 1990)
"Furosemide (5 mg/kg) was injected intra-arterially in young (10-11 week old) and aged (21-22 month old) Wistar rats at 1000 hrs or at 2200 hrs."1.28Chronopharmacological study of furosemide; (IV). Examination in aged rats. ( Ebihara, A; Fujimura, A, 1990)
"130 1 kg-1) but the elimination half-life was 70 +/- 20 min in the young and 102 +/- 33 min in the elderly (P less than 0."1.27The pharmacokinetics of frusemide are influenced by age. ( Andreasen, F; Hansen, U; Husted, SE; Jansen, JA, 1983)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199028 (37.84)18.7374
1990's22 (29.73)18.2507
2000's18 (24.32)29.6817
2010's6 (8.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nazmi, A1
Weatherall, M1
Wilkins, B1
Robinson, GM1
Nakama, C1
Kamide, K1
Kawai, T1
Hongyo, K1
Ito, N1
Onishi, M1
Takeya, Y1
Yamamoto, K1
Sugimoto, K1
Rakugi, H1
Bueters, RR1
Jeronimus-Klaasen, A1
Maicas, N1
Florquin, S1
van den Heuvel, LP1
Schreuder, MF1
Schlender, JF1
Meyer, M1
Thelen, K1
Krauss, M1
Willmann, S1
Eissing, T1
Jaehde, U1
Hartman, BH1
Basak, O1
Nelson, BR1
Taylor, V1
Bermingham-McDonogh, O1
Reh, TA1
Dagan, A1
Habib, S1
Gattineni, J1
Dwarakanath, V1
Baum, M1
Oesterle, EC1
Campbell, S1
Lang, H3
Jyothi, V1
Smythe, NM1
Dubno, JR1
Schulte, BA3
Schmiedt, RA3
Velasco Cano, MV1
Runkle de la Vega, I1
Thunhorst, RL1
Johnson, AK1
Okamura, HO1
Karam, M1
Feustel, PJ1
Goldfarb, CR1
Kogan, BA1
Cosgriff, PS1
Gordon, I1
Davidovic, M1
Trailov, D1
Milosevic, D1
Radosavljevic, B1
Milanovic, P1
Djurica, S1
Loncar-Stevanovic, H1
Stevic, R1
Ye, T1
Liu, ZQ1
Mu, JJ1
Fu, XH1
Yang, J1
Gao, BL1
Zhang, XH1
Kaye, M1
Kennes, BJ1
Moest, PF1
Neve, PE1
Andreasen, F3
Hansen, U2
Husted, SE2
Mogensen, CE1
Chaudhry, AY1
Bing, RF1
Castleden, CM1
Swales, JD1
Napier, CJ1
Jansen, JA1
Kelly, JG1
Copeland, S1
McDevitt, DG1
Kerremans, AL1
Tan, Y1
van Baars, H1
van Ginneken, CA1
Gribnau, FW1
Saruta, T1
Suzuki, A1
Hayashi, M1
Yasui, T1
Eguchi, T1
Kato, E1
Nakamaru, M3
Ogihara, T3
Hata, T3
Naka, T3
Mikami, H3
Maruyama, A3
Kumahara, Y3
Iwanaga, K3
Higaki, J1
Murakami, K1
Noordewier, B1
Bailie, MD1
Hook, JB1
Husted, S1
Bräunlich, H1
Boussairi, EH1
Sacquet, J1
Sassard, J1
Benzoni, D1
Fujimura, A3
Sudoh, T1
Ebihara, A3
Voelker, JR1
Cobb, SL1
Bowsher, RR1
Johanson, CE1
Preston, JE1
Worthington, MG1
Wendt, MC1
Opie, LH1
Bergendal, L1
Friberg, A1
Schaffrath, A1
Olde Rikkert, MG1
Deurenberg, P1
Jansen, RW1
van't Hof, MA1
Hoefnagels, WH1
Osorio, AV1
Alon, MM1
Nichols, MA1
Alon, US1
Gharaibeh, NS1
Ehrlich, I1
Lohrke, S1
Friauf, E1
Epstein, FH1
Prasad, P1
Suter, PM1
Haller, J1
Hany, A1
Vetter, W1
DeFazio, RA1
Keros, S1
Quick, MW1
Hablitz, JJ1
Fazio, M1
Bardelli, M1
Cominotto, F1
Fiammengo, F1
Fabris, B1
Fischetti, F1
Candido, R1
Pascazio, L1
Lapasin, R1
Carretta, R1
Hevers, W1
Lüddens, H1
Grim, CE2
Weinberger, MH2
Henry, DP1
Luft, FC2
Fineberg, NS2
Fineberg, N1
Weinberger, MC1
Miyamoto, Y1
Itoh, T1
Abe, K1
Irokawa, N1
Saito, K1
Yasujima, M1
Miyazaki, S1
Seino, M1
Kusaka, T1
Sakurai, Y1
Chiba, S1
Ritsu, K1
Yoshinaga, K1
Vetter, H1
Alasso, I1
Appenheimer, M1
Weiand, H1
Stelkens, H1
Lucas, R1
Glänzer, K1
Witassek, F1
Stumpe, KO1
Trübestein, G1
Krück, F1
Fishback, DB1
Ohira, H1
Shiga, T1
Ohashi, K1
Viani, A4
Pacifici, GM4
Zawada, ET1
Weiss, Y1
Chenard, A1
De Kermadec, JM1
Tertrain, F1
Abiteboul, M1
Melendez, E1
Reyes, JL1
Melendez, MA1
Cappiello, M1
Silvestri, D1
Kay, MM1
Zicha, J1
Duhm, J1
Kuchel, O1
Miceli, JJ1
Kramer, PA1
Chapron, DJ1
Rosenkrantz, TS1
Raye, JR1
Wilson, TW1
McCaulay, FA1
Waslen, TA1
Adamson, GM1
Harman, AW1
Wigham, CG1
Hodson, SA1
Taddeucci-Brunelli, G1
Martinez, JR1
Camden, J1
von Harnack, GA1
Eckart, D1
Doberauer, W2
Formanek, K2
Wick, G2
Dalin, P1
Björkman, C1
Nizard, C1
Noblesse, E1
Boisdé, C1
Moreau, M1
Faussat, AM1
Schnebert, S1
Mahé, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Salt-Sensitivity and Immunity Cell Activation[NCT03753204]Phase 1/Phase 220 participants (Anticipated)Interventional2021-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for furosemide and Aging

ArticleYear
[Current considerations in syndrome of inappropriate secretion of antidiuretic hormone/syndrome of inappropriate antidiuresis].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2010, Volume: 57 Suppl 2

    Topics: Aging; Aquaporin 2; Arginine Vasopressin; Blood Volume; Brain Edema; Combined Modality Therapy; Diag

2010
Drosophila to bacteriophage to erythrocyte: the erythrocyte as a model for molecular and membrane aging of terminally differentiated cells.
    Gerontology, 1991, Volume: 37, Issue:1-3

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1991

Trials

3 trials available for furosemide and Aging

ArticleYear
Diuretic renogram clearance half-times in the diagnosis of obstructive uropathy: effect of age and previous surgery.
    Nuclear medicine communications, 2003, Volume: 24, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Diuresis; D

2003
Validation of multifrequency bioelectrical impedance analysis in monitoring fluid balance in healthy elderly subjects.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1997, Volume: 52, Issue:3

    Topics: Aged; Aging; Body Fluids; Body Water; Body Weight; Diuretics; Electric Impedance; Evaluation Studies

1997
Maintenance of blood pressure control in elderly hypertensives on ketoprofen.
    Scandinavian journal of rheumatology. Supplement, 1991, Volume: 91

    Topics: Acebutolol; Aged; Aged, 80 and over; Aging; Atenolol; Blood Pressure; Double-Blind Method; Drug Ther

1991

Other Studies

69 other studies available for furosemide and Aging

ArticleYear
Thiamin concentration in geriatric hospitalized patients using frusemide.
    Journal of nutrition in gerontology and geriatrics, 2014, Volume: 33, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Diuretics; Female; Furosemide; Glomerular Filtration Rate; Heart Fai

2014
The influence of aging on the diagnosis of primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captop

2014
The Effects of Early Postnatal Diuretics Treatment on Kidney Development and Long-Term Kidney Function in Wistar Rats.
    Nephron, 2016, Volume: 132, Issue:2

    Topics: Acute-Phase Proteins; Aging; Animals; Apoptosis; Blood Pressure; Body Weight; Cell Proliferation; Di

2016
Development of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly Individuals.
    Clinical pharmacokinetics, 2016, Volume: 55, Issue:12

    Topics: Aging; Body Weights and Measures; Dose-Response Relationship, Drug; Drug Administration Routes; Drug

2016
Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea.
    Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:3

    Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Cochlea; Ear, Inner; Epithelium; Furos

2009
Prenatal programming of rat thick ascending limb chloride transport by low-protein diet and dexamethasone.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:1

    Topics: Aging; Animals; Antihypertensive Agents; Biological Transport; Blood Pressure; Chlorides; Dexamethas

2009
Supporting cell characteristics in long-deafened aged mouse ears.
    Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:4

    Topics: Aging; Animals; Biomarkers; Calcium-Binding Proteins; Cell Differentiation; Deafness; Diuretics; Fur

2009
Chronic reduction of endocochlear potential reduces auditory nerve activity: further confirmation of an animal model of metabolic presbyacusis.
    Journal of the Association for Research in Otolaryngology : JARO, 2010, Volume: 11, Issue:3

    Topics: Action Potentials; Adaptation, Physiological; Aging; Animals; Cochlear Nerve; Disease Models, Animal

2010
Thirst and salt appetite responses in young and old Brown Norway rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:2

    Topics: Aging; Animals; Antihypertensive Agents; Appetite; Body Fluids; Body Weight; Captopril; Drinking Beh

2003
Effects of furosemide applied chronically to the round window: a model of metabolic presbyacusis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Nov-01, Volume: 22, Issue:21

    Topics: Action Potentials; Aging; Animals; Auditory Threshold; Cochlea; Disease Models, Animal; Female; Furo

2002
Effects of chronic furosemide treatment and age on cell division in the adult gerbil inner ear.
    Journal of the Association for Research in Otolaryngology : JARO, 2003, Volume: 4, Issue:2

    Topics: Action Potentials; Aging; Animals; Bromodeoxyuridine; Cell Division; Cochlea; Differential Threshold

2003
Diuretic renogram clearance half-times in the diagnosis of obstructive uropathy: effect at age and previous surgery.
    Nuclear medicine communications, 2003, Volume: 24, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Diuresis; D

2003
Magnesium, aging, and the elderly patient.
    TheScientificWorldJournal, 2004, Jul-29, Volume: 4

    Topics: Aged; Aged, 80 and over; Aging; Autopsy; Bumetanide; Diuretics; Female; Furosemide; Humans; Longevit

2004
Blood pressure change with age in salt-sensitive teenagers.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2004, Volume: 19, Issue:4

    Topics: Adolescent; Aging; Blood Pressure; Blood Volume; Female; Furosemide; Humans; Infusions, Intravenous;

2004
Aging, circadian weight change, and nocturia.
    Nephron. Physiology, 2008, Volume: 109, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Bed Rest; Body Weight; Circadian Rhythm; Diureti

2008
Biochemical events associated with lymphocyte activation in aging. K+ transport and sensitivity of the Na+-K+ pump to digoxine.
    Experimental gerontology, 1982, Volume: 17, Issue:4

    Topics: Adult; Aged; Aging; Biological Transport; Cells, Cultured; Digoxin; Furosemide; Humans; Ion Channels

1982
The influence of intravenous furosemide on the renal excretion pattern of protein and protein degradation products.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:5

    Topics: Aged; Aging; Albuminuria; beta 2-Microglobulin; Creatine; Furosemide; Humans; Hydrogen-Ion Concentra

1984
The effect of ageing on the response to frusemide in normal subjects.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:3

    Topics: Adult; Aging; Blood Pressure; Female; Furosemide; Humans; Male; Potassium; Renin; Sodium

1984
The pharmacokinetics of frusemide are influenced by age.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:4

    Topics: Adult; Aged; Aging; Body Weight; Creatinine; Furosemide; Humans; Kinetics; Male; Middle Aged; Protei

1983
Erythrocyte cation transport and age: effects of digoxin and furosemide.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Binding Sites; Biological Transport, Active; Digoxin; Erythrocytes;

1983
Furosemide kinetics and dynamics in aged patients.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:2

    Topics: Adult; Aged; Aging; Creatinine; Female; Furosemide; Humans; Kinetics; Male

1983
Mechanism of age-related changes in renin and adrenocortical steroids.
    Journal of the American Geriatrics Society, 1980, Volume: 28, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aging; Aldosterone; Angiotensin II; Corticosterone; Desoxycort

1980
[Effect of age on active and inactive plasma renin levels in normal subjects and in patients with essential hypertension (author's transl)].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1980, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Furosemide; Humans; Hypertension; Middle Aged; Renin

1980
Effect of age on active and inactive plasma renin in normal subjects and in patients with essential hypertension.
    Journal of the American Geriatrics Society, 1981, Volume: 29, Issue:8

    Topics: Adult; Aged; Aging; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Physical Exertion;

1981
The effect of age on active and cryoactivatable inactive plasma renin in normal subjects and patients with essential hypertension.
    Japanese circulation journal, 1981, Volume: 45, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Furosemide; Humans; Hypertension; Middle Aged; Renin

1981
Effect of furosemide on renal function of the newborn piglet.
    Pediatric pharmacology (New York, N.Y.), 1980, Volume: 1, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Diuresis; Electrolytes; Furosemide; Glomerular Filtration Rate; In

1980
The binding of furosemide to serum proteins in elderly patients: displacing effect of phenprocoumon.
    Acta pharmacologica et toxicologica, 1980, Volume: 47, Issue:3

    Topics: 4-Hydroxycoumarins; Adult; Aged; Aging; Binding, Competitive; Blood Proteins; Female; Furosemide; Hu

1980
Renal pharmacokinetics of furosemide in young and adult rats.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 246, Issue:1

    Topics: Aging; Animals; Furosemide; Kidney; Kidney Cortex; Kinetics; Male; p-Aminohippuric Acid; Rabbits; Ra

1980
Thromboxane A2-prostaglandin H2 and renovascular hypertension in rats.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: Aging; Angiotensin II; Animals; Arginine Vasopressin; Baroreflex; Blood Pressure; Body Weight; Capry

1994
Decrease in the time-dependent difference in urinary excretion of furosemide with age.
    Chronobiology international, 1994, Volume: 11, Issue:2

    Topics: Administration, Oral; Aging; Animals; Circadian Rhythm; Drug Administration Schedule; Furosemide; Ma

1994
Improved HPLC-radioimmunoassay for quantifying angiotensin II in plasma.
    Clinical chemistry, 1994, Volume: 40, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aging; Angiotensin II; Chromatography, High Pressure Liquid; Diet; F

1994
Potassium efflux from infant and adult rat choroid plexuses: effects of CSF anion substitution, N-ethylmaleimide and Cl transport inhibitors.
    Neuroscience letters, 1994, Mar-14, Volume: 169, Issue:1-2

    Topics: Aging; Animals; Anions; Benzoates; Bumetanide; Chlorides; Choroid Plexus; Ethylmaleimide; Female; Fu

1994
Sodium transport in hypertension: assessment of membrane-associated defects in South African black and white hypertensives.
    Journal of human hypertension, 1993, Volume: 7, Issue:3

    Topics: Adenosine Triphosphate; Adult; Aging; Alcohol Drinking; Antihypertensive Agents; Black People; Carri

1993
Potential drug--drug interactions in 5,125 mostly elderly out-patients in Gothenburg, Sweden.
    Pharmacy world & science : PWS, 1995, Sep-22, Volume: 17, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Carbamazepine; Cohort Studies; Digoxin; Drug Interactions; Drug Pres

1995
Effect of age on furosemide-induced nephrocalcinosis in the rat.
    Biology of the neonate, 1998, Volume: 73, Issue:5

    Topics: Aging; Animals; Calcium; Diuresis; Drinking; Eating; Furosemide; Male; Nephrocalcinosis; Rats; Rats,

1998
N-ethylmaliemide (NEM)-stimulated passive potassium transport in camel erythrocytes: inhibitory effects of age, furosemide, sodium fluoride and okadaic acid.
    Veterinary journal (London, England : 1997), 1999, Volume: 157, Issue:1

    Topics: Aging; Animals; Biological Transport; Camelus; Carrier Proteins; Erythrocyte Aging; Erythrocytes; Et

1999
Shift from depolarizing to hyperpolarizing glycine action in rat auditory neurones is due to age-dependent Cl- regulation.
    The Journal of physiology, 1999, Oct-01, Volume: 520 Pt 1

    Topics: Aging; Animals; Animals, Newborn; Chloride Channels; Diuretics; Electrophysiology; Evoked Potentials

1999
Effects of furosemide on medullary oxygenation in younger and older subjects.
    Kidney international, 2000, Volume: 57, Issue:5

    Topics: Adult; Aging; Female; Furosemide; Humans; Ibuprofen; Kidney Medulla; Magnetic Resonance Imaging; Mal

2000
Diuretic use: a risk for subclinical thiamine deficiency in elderly patients.
    The journal of nutrition, health & aging, 2000, Volume: 4, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Diuretics; Dose-Response Relationship, Drug; Erythrocytes; Female; F

2000
Potassium-coupled chloride cotransport controls intracellular chloride in rat neocortical pyramidal neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Nov-01, Volume: 20, Issue:21

    Topics: Aging; Animals; Carrier Proteins; Chlorides; Diuretics; Dose-Response Relationship, Drug; Evoked Pot

2000
Haemoconcentration, shear-stress increase and carotid artery diameter regulation after furosemide administration in older hypertensives.
    Experimental gerontology, 2001, Volume: 36, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Pressure; Blood Viscosity; Carotid Artery, Com

2001
Pharmacological heterogeneity of gamma-aminobutyric acid receptors during development suggests distinct classes of rat cerebellar granule cells in situ.
    Neuropharmacology, 2002, Volume: 42, Issue:1

    Topics: Aging; Algorithms; Animals; Bicuculline; Carbolines; Cerebellum; Convulsants; Diazepam; Diuretics; E

2002
Biochemical correlates of the increase in blood pressure with age.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Aging; Aldosterone; Black People; Blood Pressure; Body Weight; Furosemide; Humans; Norepinephrine; R

1978
Effects of volume expansion and contraction in normotensive whites, blacks, and subjects of different ages.
    Circulation, 1979, Volume: 59, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Black People; Blood Pressure; Blood Volume; Female; Fur

1979
[Plasma renin activity in essential hypertension with respect to aging, hypertension severity and furosemide test (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1978, Oct-10, Volume: 67, Issue:10

    Topics: Adult; Aged; Aging; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Male; Middle

1978
[The influence of aging on renin release stimulated by furosemide and upright posture in essential hypertension (author's transl)].
    Nihon Jinzo Gakkai shi, 1978, Volume: 20, Issue:9

    Topics: Adolescent; Adult; Aged; Aging; Female; Furosemide; Humans; Hypertension; Injections, Intravenous; M

1978
[Plasma renin activity and plasma aldosterone in essential hypertension: effect of age and diastolic blood pressure].
    Schweizerische medizinische Wochenschrift, 1976, Dec-04, Volume: 106, Issue:49

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Creatinine; Furosemide; Humans; Hypertension; Middle Ag

1976
An approach to the treatment of hypertension in the aged.
    Angiology, 1976, Volume: 27, Issue:4

    Topics: Administration, Oral; Aged; Aging; Blood Pressure; Diet; Diuretics; Drug Combinations; Furosemide; H

1976
Chronopharmacology of furosemide in the elderly.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Drug Administration Schedule; Female; Furosemide; Humans; Injections

1992
Quantitative contribution of endogenous compounds and hypoalbuminemia in reducing the binding of furosemide in the plasma of newborn infants.
    Developmental pharmacology and therapeutics, 1992, Volume: 18, Issue:1-2

    Topics: Aging; Apazone; Dialysis; Dimethyl Sulfoxide; Furosemide; Humans; Infant, Newborn; Protein Binding;

1992
Geriatrics nephrology.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:4

    Topics: Aged; Aging; Captopril; Digoxin; Furosemide; Heart Failure; Humans; Hypertension; Kidney Diseases; L

1992
Effects of furosemide on the renal functions of the unanesthetized newborn rat.
    Developmental pharmacology and therapeutics, 1991, Volume: 17, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Consciousness; Diuresis; Electrolytes; Female; Furosemide; Glomeru

1991
Sodium and volume sensitivity of blood pressure. Age and pressure change over time.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:1

    Topics: Adult; Aged; Aging; Blood Pressure; Blood Volume; Cross-Sectional Studies; Diastole; Furosemide; Hum

1991
Binding of furosemide to albumin isolated from human fetal and adult serum.
    Developmental pharmacology and therapeutics, 1991, Volume: 16, Issue:1

    Topics: Adult; Aging; Binding Sites; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Fetal Blood; Fu

1991
Influence of chronic alterations of salt intake and aging on the kinetic of red cell Na+ and K+ transport in Sprague-Dawley rats.
    Physiologia Bohemoslovaca, 1990, Volume: 39, Issue:1

    Topics: Aging; Animals; Biological Transport; Blood Pressure; Carrier Proteins; Erythrocytes; Furosemide; Ki

1990
Peripheral dopamine in essential hypertension. An early defense against hypertension failing during its progression?
    American journal of hypertension, 1990, Volume: 3, Issue:6 Pt 2

    Topics: Aging; Dopamine; Furosemide; Homovanillic Acid; Humans; Hypertension; Longitudinal Studies; Renin

1990
Pharmacokinetics and dynamics of furosemide in the newborn piglet.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Furosemide; Glomerular Filtration Rate; Infusions, In

1990
Chronopharmacological study of furosemide; (IV). Examination in aged rats.
    Life sciences, 1990, Volume: 47, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Chronobiology Phenomena; Furosemide; Male; Rats; Rats, Inbred

1990
Bilirubin displaces furosemide from serum protein: the effect is greater in newborn infants than adult subjects.
    Developmental pharmacology and therapeutics, 1989, Volume: 14, Issue:2

    Topics: Adult; Aging; Bilirubin; Binding, Competitive; Blood Proteins; Female; Fetal Blood; Furosemide; Huma

1989
Effects of aging on responses to furosemide.
    Prostaglandins, 1989, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Body Weight; Diuresis; Female; Fu

1989
Comparison of the susceptibility of hepatocytes from postnatal and adult mice to hepatotoxins.
    Biochemical pharmacology, 1988, Nov-01, Volume: 37, Issue:21

    Topics: Acetaminophen; Aging; Animals; Animals, Newborn; Catalase; Furosemide; Glutathione; Glutathione Pero

1988
Physiological changes in the cornea of the ageing eye.
    Eye (London, England), 1987, Volume: 1 ( Pt 2)

    Topics: Aged; Aged, 80 and over; Aging; Bicarbonates; Biological Transport, Active; Cell Membrane Permeabili

1987
Serum protein binding of furosemide in newborn infants and children.
    Developmental pharmacology and therapeutics, 1987, Volume: 10, Issue:6

    Topics: Adolescent; Adult; Aging; Blood Proteins; Child; Child, Preschool; Female; Fetal Blood; Furosemide;

1987
42K spaces in submandibular gland of early postnatal rats: effects of carbachol and transport inhibitors.
    Experientia, 1986, Sep-15, Volume: 42, Issue:9

    Topics: Aging; Animals; Animals, Newborn; Biological Transport; Carbachol; Furosemide; Ouabain; Potassium; P

1986
[Age-specific dosage of the diuretic furosemide].
    Monatsschrift fur Kinderheilkunde, 1965, Volume: 113, Issue:8

    Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Diuretics; Furosemide; Humans; Infant

1965
[Differences in saluresis in old and young rats].
    Zeitschrift fur Alternsforschung, 1966, Volume: 19, Issue:3

    Topics: Age Factors; Aging; Animals; Chlorides; Diuresis; Electrolytes; Furosemide; Male; Natriuresis; Potas

1966
[The effect of water extraction on the water-electrolyte balance in old and young rats].
    Zeitschrift fur Alternsforschung, 1966, Volume: 19, Issue:3

    Topics: Aging; Animals; Blood Proteins; Chlorides; Dehydration; Diuresis; Electrolytes; Furosemide; Male; Ph

1966
Adult beetle grazing induces willow trichome defence against subsequent larval feeding.
    Oecologia, 2003, Volume: 134, Issue:1

    Topics: Adaptation, Physiological; Aging; Animals; Coleoptera; Eating; Larva; Plant Leaves; Salix

2003
Heat shock protein 47 expression in aged normal human fibroblasts: modulation by Salix alba extract.
    Annals of the New York Academy of Sciences, 2004, Volume: 1019

    Topics: Adult; Aged; Aging; Animals; Fibroblasts; Flow Cytometry; Free Radicals; Heat-Shock Proteins; HSP47

2004