furosemide has been researched along with Acute Brain Injuries in 14 studies
Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Continuous infusion of 3% hypertonic saline + furosemide is effective and safe for intracranial pressure control." | 1.42 | Efficacy and Safety of Continuous Micro-Pump Infusion of 3% Hypertonic Saline combined with Furosemide to Control Elevated Intracranial Pressure. ( Cheng, H; Fang, W; Gao, G; Gao, L; Li, L; Li, M; Li, Y; Li, Z; Wang, B; Yang, Y; Zhang, X; Zhao, B, 2015) |
| "Seventeen had Glasgow Coma Scales of 3 to 4 and 23 scales of 5 to 7." | 1.27 | Early prediction of outcome after severe head injury in children. ( Pfenninger, J, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cragoe, EJ | 1 |
| Gould, NP | 1 |
| Woltersdorf, OW | 1 |
| Ziegler, C | 1 |
| Bourke, RS | 1 |
| Nelson, LR | 1 |
| Kimelberg, HK | 1 |
| Waldman, JB | 1 |
| Popp, AJ | 1 |
| Sedransk, N | 1 |
| Li, Y | 1 |
| Li, Z | 1 |
| Li, M | 1 |
| Yang, Y | 1 |
| Wang, B | 2 |
| Gao, L | 1 |
| Zhang, X | 1 |
| Cheng, H | 1 |
| Fang, W | 1 |
| Zhao, B | 1 |
| Gao, G | 1 |
| Li, L | 1 |
| Tang, ME | 1 |
| Lobel, DA | 1 |
| Mtchedlishvili, Z | 1 |
| Lepsveridze, E | 1 |
| Xu, H | 1 |
| Kharlamov, EA | 1 |
| Lu, B | 1 |
| Kelly, KM | 1 |
| Todd, MM | 1 |
| Cutkomp, J | 1 |
| Brian, JE | 1 |
| Millet, A | 1 |
| Pfenninger, J | 1 |
| McNamara, M | 1 |
| Quinn, C | 1 |
| Kirdan, KP | 1 |
| Kuberger, MB | 1 |
| Ivanov, LB | 1 |
| Dabrowska, E | 1 |
| Jagodziński, Z | 1 |
| Michalak, W | 1 |
| Baethmann, A | 1 |
| Lanksch, W | 1 |
| Schmiedek, P | 1 |
| Hayakawa, I | 1 |
| Cabrini, GP | 1 |
| Giovanelli, M | 1 |
| Infuso, L | 1 |
| Nicola, GC | 1 |
| Galle, P | 1 |
| Staudacher, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Mannitol Alone Versus Different Doses of Mannitol in Combination With Furosemide on Brain Relaxation in Supratentorial Mass Resection Surgery[NCT02712476] | 47 participants (Actual) | Interventional | 2013-07-31 | Completed | |||
| The Effect of Furosemide Versus Placebo on Brain Relaxation and Incidence of Significant Intravascular Volume Depletion in Human Subjects Receiving Mannitol[NCT01054404] | 23 participants (Actual) | Interventional | 2010-02-28 | Terminated (stopped due to Concern for volume depletion and electrolyte abnormalities in furosemide arm.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Rating of brain relaxation will be on a 4-point scale:~0 = brain very relaxed under dura, acceptable~= brain adequately relaxed under dura, acceptable~= brain slightly tense under dura, acceptable~= brain very tense under bulging dura, unacceptable" (NCT01054404)
Timeframe: just prior to dural opening for each subject
| Intervention | units on a scale 0-3 (Mean) |
|---|---|
| Furosemide | 1.5 |
| Placebo | 1.3 |
3 reviews available for furosemide and Acute Brain Injuries
| Article | Year |
|---|---|
Severe traumatic brain injury: maximizing outcomes.
Topics: Bacterial Infections; Brain Injuries; Cerebrovascular Circulation; Diuretics; Furosemide; Humans; Hy | 2009 |
[Effect of osmotic diuretics, enzyme-inhibiting diuretics and neuroleptics on cerebral perfusion pressure].
Topics: Acetazolamide; Adrenal Cortex Hormones; Animals; Antipsychotic Agents; Brain Edema; Brain Injuries; | 1983 |
Epidural intracranial pressure monitoring: theory and clinical application.
Topics: Barbiturates; Brain; Brain Diseases; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Epidu | 1981 |
1 trial available for furosemide and Acute Brain Injuries
| Article | Year |
|---|---|
[Effect of glucose and lasix on the functional state of the brain in craniocerebral injury in children].
Topics: Adolescent; Brain; Brain Injuries; Child; Clinical Trials as Topic; Drug Evaluation; Electroencephal | 1976 |
10 other studies available for furosemide and Acute Brain Injuries
| Article | Year |
|---|---|
Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids.
Topics: Animals; Astrocytes; Bicarbonates; Brain Injuries; Carboxylic Acids; Cats; Cerebral Cortex; Chemical | 1982 |
Efficacy and Safety of Continuous Micro-Pump Infusion of 3% Hypertonic Saline combined with Furosemide to Control Elevated Intracranial Pressure.
Topics: Aged; Brain Injuries; Female; Furosemide; Humans; Infusion Pumps; Intracranial Hypertension; Male; M | 2015 |
Increase of GABAA receptor-mediated tonic inhibition in dentate granule cells after traumatic brain injury.
Topics: Animals; Brain Injuries; Dentate Gyrus; Diazepam; Furosemide; GABA Agonists; GABA Modulators; GABA-A | 2010 |
Influence of mannitol and furosemide, alone and in combination, on brain water content after fluid percussion injury.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Water; Brain Chemistry; Brain Edema; Brain Injurie | 2006 |
Influence of mannitol and furosemide, alone and in combination, on brain water content after fluid percussion injury.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Water; Brain Chemistry; Brain Edema; Brain Injurie | 2006 |
Influence of mannitol and furosemide, alone and in combination, on brain water content after fluid percussion injury.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Water; Brain Chemistry; Brain Edema; Brain Injurie | 2006 |
Influence of mannitol and furosemide, alone and in combination, on brain water content after fluid percussion injury.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Water; Brain Chemistry; Brain Edema; Brain Injurie | 2006 |
Early prediction of outcome after severe head injury in children.
Topics: Adolescent; Blood Coagulation Tests; Brain Death; Brain Injuries; Child; Child, Preschool; Coma; Dex | 1984 |
[Remarks on conservative treatment of cerebral hematoma].
Topics: Accidental Falls; Accidents, Traffic; Adolescent; Adult; Aged; Brain Injuries; Cerebral Hemorrhage; | 1992 |
Formation and treatment of cerebral edema.
Topics: Aldosterone; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Dexamethasone; Ethacrynic Ac | 1974 |
[Clinical studies on a new intracranial pressure reducing agent].
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Diseases; Brain Injuries; Brain Neoplasms; Craniopharyng | 1967 |
[Changes in cerebrospinal fluid pressure in closed cranial injuries as related to drug therapy].
Topics: Brain Edema; Brain Injuries; Caffeine; Contusions; Dexamethasone; Furosemide; Hematoma, Subdural; In | 1967 |
[On the influence of dehydrated drug preparations on cerebrospinal fluid pressure in head-brain injuries].
Topics: Brain Injuries; Cerebrospinal Fluid; Furosemide; Humans; Phytotherapy; Plants, Medicinal; Pressure | 1967 |