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furazolidone and Duodenal Ulcer

furazolidone has been researched along with Duodenal Ulcer in 26 studies

Furazolidone: A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone acts by gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
furazolidone : A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera.

Duodenal Ulcer: A PEPTIC ULCER located in the DUODENUM.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the furazolidone-based triple therapy in children with symptomatic H pylori gastritis."9.12Furazolidone-based triple therapy for H pylori gastritis in children. ( Bonucci, VC; Carelli, AP; Fukushima, E; Kawakami, E; Langner, M; Machado, RS; Ogata, SK; Patricio, FR, 2006)
"To evaluate the efficacy of omeprazole plus clarithromycin and furazolidone in Helicobacter pylori eradication and duodenal ulcer healing in Brazilian patients."9.09Omeprazole, clarithromycin and furazolidone for the eradication of Helicobacter pylori in patients with duodenal ulcer. ( Cabral, MM; Dani, R; De Castro, LP; Dias, MG; Franco, JM; Magalhães, LC; Mendes, GS; Moreira, LS; Queiroz, DM; Rocha, GA; Salles, PG; Toppa, NH, 1999)
"The histamine concentration of the oxyntic mucosa was determined in Helicobacter pylori-positive patients with duodenal ulcer before and after antimicrobial therapy and in H."7.68Histamine content of the oxyntic mucosa from duodenal ulcer patients: effect of Helicobacter pylori eradication. ( Coelho, LG; Cunha-Melo, JR; Lima Júnior, GF; Mendes, EN; Moura, SB; Oliveira, CA; Passos, MC; Queiroz, DM; Resende, LM; Rocha, GA, 1993)
"The present experiments examined the protective effect of the nitrofuran drugs, furazolidone (FZ) and nitrofurazone (NF), on duodenal ulceration induced by cysteamine or indometacin in rats."7.68Effect of nitrofurans on duodenal ulceration induced by cysteamine or indometacin. ( Ali, BH, 1991)
"Wei-Yan-Ning and Furazolidone were used separately in the treatment of 62 cases of gastritis and gastric ulcer caused by pyloric campylobacteria."7.67[Comparative study of the effect of wei-yan-ning and furazolidone in the treatment of gastritis and gastric ulcer caused by pyloric Campylobacter]. ( Song, XR; Zhang, BM, 1989)
"The effect of furazolidone, a monoamine oxidase (MAO) inhibitor, on cysteamine-induced duodenal ulcer and gut catecholamines was studied in rats, since previous reports have suggested protective effects of MAO inhibitors against other forms of experimental mucosal injury."7.67Effect of furazolidone on gut catecholamine in cysteamine-induced duodenal ulcer in the rat. ( Xing, LP; Zheng, ZT, 1988)
"Furazolidone was tried in several developing countries and showed good results in some trials."5.37To compare the efficacy of triple therapy with furazolidone, amoxicillin and omeprazole for two weeks and three weeks in the eradication of Helicobacter pylori in Bangladeshi duodenal ulcer patients. ( Hasan, M; Islam, N; Masud, H; Raihan, AS; Roy, PK; Saha, SK, 2011)
"To evaluate the furazolidone-based triple therapy in children with symptomatic H pylori gastritis."5.12Furazolidone-based triple therapy for H pylori gastritis in children. ( Bonucci, VC; Carelli, AP; Fukushima, E; Kawakami, E; Langner, M; Machado, RS; Ogata, SK; Patricio, FR, 2006)
"To evaluate the efficacy of omeprazole plus clarithromycin and furazolidone in Helicobacter pylori eradication and duodenal ulcer healing in Brazilian patients."5.09Omeprazole, clarithromycin and furazolidone for the eradication of Helicobacter pylori in patients with duodenal ulcer. ( Cabral, MM; Dani, R; De Castro, LP; Dias, MG; Franco, JM; Magalhães, LC; Mendes, GS; Moreira, LS; Queiroz, DM; Rocha, GA; Salles, PG; Toppa, NH, 1999)
"In order to explore the optimal regimens for the eradication of Helicobacter pylori (Hp), eighty-eight patients with duodenal ulcer (DU) or non-ulcer dyspepsia and Hp infection, defined by culture and histology, received the one-week triple therapy with clarithromycin (Cla), furazolidone (Fur) plus lansoprazole (Lan) or colloidal bismuth subcitrate (CBS)."5.08[Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection]. ( Liu, W; Lü, B; Xiao, S, 1996)
" Helicobacter pylori status and the histology of the antral and oxyntic mucosa were evaluated in 25 patients with duodenal ulcer treated with a triple schedule of furazolidone, metronidazole and amoxicillin, and in 16 patients treated only with cimetidine."3.68Histology of the mucosa of gastric antrum and body before and after eradication of Helicobacter pylori. ( Barbosa, AJ; Castro, LP; Coelho, LG; Lima Júnior, GF; Mendes, EN; Oliveira, CA; Passos, MC; Queiroz, DM; Resende, LM; Rocha, GA, 1993)
"The histamine concentration of the oxyntic mucosa was determined in Helicobacter pylori-positive patients with duodenal ulcer before and after antimicrobial therapy and in H."3.68Histamine content of the oxyntic mucosa from duodenal ulcer patients: effect of Helicobacter pylori eradication. ( Coelho, LG; Cunha-Melo, JR; Lima Júnior, GF; Mendes, EN; Moura, SB; Oliveira, CA; Passos, MC; Queiroz, DM; Resende, LM; Rocha, GA, 1993)
"Forty-eight patients with endoscopically proven duodenal ulcer (DU) and Helicobacter pylori infection detected by 14C-urea breath test (BT) were assigned to 5 days of treatment with furazolidone, metronidazole, and amoxicillin in addition to eventual classical anti-ulcer agents if necessary."3.68Duodenal ulcer and eradication of Helicobacter pylori in a developing country. An 18-month follow-up study. ( Brandao, MJ; Castro, LP; Chausson, Y; Coelho, LG; Costa, EL; Maia, AF; Passos, MC; Rodrigues, DC, 1992)
"The present experiments examined the protective effect of the nitrofuran drugs, furazolidone (FZ) and nitrofurazone (NF), on duodenal ulceration induced by cysteamine or indometacin in rats."3.68Effect of nitrofurans on duodenal ulceration induced by cysteamine or indometacin. ( Ali, BH, 1991)
"Wei-Yan-Ning and Furazolidone were used separately in the treatment of 62 cases of gastritis and gastric ulcer caused by pyloric campylobacteria."3.67[Comparative study of the effect of wei-yan-ning and furazolidone in the treatment of gastritis and gastric ulcer caused by pyloric Campylobacter]. ( Song, XR; Zhang, BM, 1989)
"The purpose of this study was to investigate the protective role of furazolidone against the formation of duodenal ulcer induced by cysteamine and the effect of furazolidone on NE, DA and 5-HT concentrations in various brain regions (telencephalon, diencephalon and brainstem)."3.67[Effects of furazolidone on brain monoamines in the treatment of peptic ulcer]. ( Huang, CW; Zheng, ZT, 1989)
"The effect of furazolidone, a monoamine oxidase (MAO) inhibitor, on cysteamine-induced duodenal ulcer and gut catecholamines was studied in rats, since previous reports have suggested protective effects of MAO inhibitors against other forms of experimental mucosal injury."3.67Effect of furazolidone on gut catecholamine in cysteamine-induced duodenal ulcer in the rat. ( Xing, LP; Zheng, ZT, 1988)
"Furazolidone has been effective against Helicobacter pylori in Iran, with no resistance, but with intolerable side effects in the second week."2.73Furazolidone-based, metronidazole-based, or a combination regimen for eradication of Helicobacter pylori in peptic ulcer disease. ( Agah, S; Ajvadi, Y; Ali-Asgari, A; Ebrahimi-Dariani, N; Khatibian, M; Malekzadeh, R; Massarrat, S; Mikaeli, J; Nasseri-Moghaddam, S; Pourshams, A; Sotoudehmanesh, R; Vahedi, H; Zendehdel, N, 2007)
"Duodenal ulcers were healed in nine of 10 (90%) patients in the BTF group and in all patients (12/12) (100%) in the OBTM group (P = N."2.70Furazolidone-based triple 'rescue therapy' vs. quadruple 'rescue therapy' for the eradication of Helicobacter pylori resistant to metronidazole. ( Domareva, I; Ganskaya, Z; Isakov, V; Koudryavtseva, L; Maev, I, 2002)
"Furazolidone was tried in several developing countries and showed good results in some trials."1.37To compare the efficacy of triple therapy with furazolidone, amoxicillin and omeprazole for two weeks and three weeks in the eradication of Helicobacter pylori in Bangladeshi duodenal ulcer patients. ( Hasan, M; Islam, N; Masud, H; Raihan, AS; Roy, PK; Saha, SK, 2011)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19904 (15.38)18.7374
1990's8 (30.77)18.2507
2000's11 (42.31)29.6817
2010's3 (11.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xie, Y1
Zhu, Y1
Zhou, H1
Lu, ZF1
Yang, Z1
Shu, X1
Guo, XB1
Fan, HZ1
Tang, JH1
Zeng, XP1
Wen, JB1
Li, XQ1
He, XX1
Ma, JH1
Liu, DS1
Huang, CB1
Xu, NJ1
Wang, NR1
Lu, NH1
Li, Y1
Wang, XY1
Shen, SR1
Fakheri, H2
Taghvaei, T1
Hosseini, V1
Bari, Z1
Saha, SK2
Masud, H1
Islam, N1
Raihan, AS1
Roy, PK1
Hasan, M1
Isakov, V1
Domareva, I1
Koudryavtseva, L1
Maev, I1
Ganskaya, Z1
Vasil'ev, IuV1
Zvenigorodskaia, LA1
Karateev, AE1
Nasonov, EL1
Radenska-Lopovok, SG1
Kawakami, E1
Machado, RS1
Ogata, SK1
Langner, M1
Fukushima, E1
Carelli, AP1
Bonucci, VC1
Patricio, FR1
Khatibian, M2
Ajvadi, Y1
Nasseri-Moghaddam, S1
Ebrahimi-Dariani, N1
Vahedi, H2
Zendehdel, N1
Sotoudehmanesh, R1
Agah, S1
Mikaeli, J1
Pourshams, A1
Ali-Asgari, A1
Malekzadeh, R3
Massarrat, S3
Tovey, FI1
Resende, LM2
Queiroz, DM3
Barbosa, AJ1
Mendes, EN2
Rocha, GA3
Coelho, LG4
Passos, MC4
Castro, LP2
Oliveira, CA2
Lima Júnior, GF2
Moura, SB1
Cunha-Melo, JR1
Liu, W1
Lü, B1
Xiao, S1
Liu, WZ2
Xiao, SD2
Shi, Y1
Wu, SM1
Zhang, DZ1
Xu, WW1
Tytgat, GN2
Dani, R1
Dias, MG1
Franco, JM1
Magalhães, LC1
Mendes, GS1
Moreira, LS1
De Castro, LP1
Toppa, NH1
Cabral, MM1
Salles, PG1
Ansari, R1
Siavoshi, F1
Alizadeh, BZ2
Eshraghian, MR1
Vakili, A1
Saghari, M1
Hu, PJ1
Lu, H1
Cui, Y1
Merat, S1
Fazel, A1
Mansour-Ghanaei, F1
Fallah, MS1
Shafaghi, A1
Chausson, Y2
Costa, EL1
Maia, AF1
Brandao, MJ1
Rodrigues, DC1
Castro, Lde P1
Ali, BH1
Zhang, BM1
Song, XR1
Huang, CW1
Zheng, ZT3
Xing, LP2

Trials

15 trials available for furazolidone and Duodenal Ulcer

ArticleYear
Furazolidone-based triple and quadruple eradication therapy for Helicobacter pylori infection.
    World journal of gastroenterology, 2014, Aug-28, Volume: 20, Issue:32

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; China; Drug Administration Schedule; Drug Therapy, Combin

2014
[Efficacy of 4 kinds of triple strategy for Helicobacter pylori eradication].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2008, Volume: 33, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer

2008
A comparison between sequential therapy and a modified bismuth-based quadruple therapy for Helicobacter pylori eradication in Iran: a randomized clinical trial.
    Helicobacter, 2012, Volume: 17, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Bismuth; Clarith

2012
Furazolidone-based triple 'rescue therapy' vs. quadruple 'rescue therapy' for the eradication of Helicobacter pylori resistant to metronidazole.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:7

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Resistance, Bacterial; Drug Therap

2002
[Fromilide (clarithromycin) in eradication of Helicobacter pylori in patients with duodenal ulcer].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Com

2002
[Efficacy of colloid bismuth subcitrate (De-Nol) in gastropathies induced by nonsteroid anti-inflammatory drugs: an open controlled 4-week trial].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:2

    Topics: Aged; Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arth

2005
Furazolidone-based triple therapy for H pylori gastritis in children.
    World journal of gastroenterology, 2006, Sep-14, Volume: 12, Issue:34

    Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Agents; Child; Child, Preschool

2006
Furazolidone-based, metronidazole-based, or a combination regimen for eradication of Helicobacter pylori in peptic ulcer disease.
    Archives of Iranian medicine, 2007, Volume: 10, Issue:2

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents, Local; Drug Therapy, Combination;

2007
[Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection].
    Zhonghua nei ke za zhi, 1996, Volume: 35, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithrom

1996
Furazolidone-containing short-term triple therapies are effective in the treatment of Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Infective Agents, Local;

1999
Omeprazole, clarithromycin and furazolidone for the eradication of Helicobacter pylori in patients with duodenal ulcer.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:12

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Brazil; Clarithromycin; Drug Therapy, C

1999
Furazolidone versus metronidazole in quadruple therapy for eradication of Helicobacter pylori in duodenal ulcer disease.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Drug Combinations; Duodenal Ulcer; Female; Furazolidone; Helicobacter

2000
A new quadruple therapy for Helicobacter pylori using tripotassium dicitrato bismuthate, furazolidone, josamycin and famotidine.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:11

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Ulcer Agents; Drug Therapy, C

2000
Clarithromycin vs. furazolidone in quadruple therapy regimens for the treatment of Helicobacter pylori in a population with a high metronidazole resistance rate.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:3

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Ulcer Agents; Clarithr

2001
Eradication of Helicobacter pylori in duodenal ulcer disease tetracycline & furazolidone vs. metronidazole & amoxicillin in omeprazole based triple therapy.
    Medical science monitor : international medical journal of experimental and clinical research, 2002, Volume: 8, Issue:3

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents, Local; Drug Therapy, Combination; Duodena

2002

Other Studies

11 other studies available for furazolidone and Duodenal Ulcer

ArticleYear
To compare the efficacy of triple therapy with furazolidone, amoxicillin and omeprazole for two weeks and three weeks in the eradication of Helicobacter pylori in Bangladeshi duodenal ulcer patients.
    Bangladesh Medical Research Council bulletin, 2011, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Bangladesh; Drug Therapy,

2011
Treatment of duodenal ulceration with Furazolidine in China preceded the discovery of its association with H pylori.
    World journal of gastroenterology, 2007, Jun-14, Volume: 13, Issue:22

    Topics: Anti-Infective Agents, Local; China; Duodenal Ulcer; Duodenum; Furazolidone; Helicobacter Infections

2007
Histology of the mucosa of gastric antrum and body before and after eradication of Helicobacter pylori.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1993, Volume: 26, Issue:12

    Topics: Adult; Amoxicillin; Drug Therapy, Combination; Duodenal Ulcer; Female; Furazolidone; Gastric Mucosa;

1993
Histamine content of the oxyntic mucosa from duodenal ulcer patients: effect of Helicobacter pylori eradication.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:8

    Topics: Adult; Amoxicillin; Drug Therapy, Combination; Duodenal Ulcer; Female; Furazolidone; Gastric Mucosa;

1993
Duodenal ulcer and eradication of Helicobacter pylori in a developing country. An 18-month follow-up study.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:5

    Topics: Amoxicillin; Brazil; Developing Countries; Drug Therapy, Combination; Duodenal Ulcer; Duodenoscopy;

1992
Five-day bismuth-free triple therapy for the eradication of Helicobacter pylori and reduction of duodenal ulcer relapse.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:8

    Topics: Adult; Amoxicillin; Breath Tests; Carbon Radioisotopes; Drug Administration Schedule; Drug Therapy,

1991
Effect of nitrofurans on duodenal ulceration induced by cysteamine or indometacin.
    Pharmacology, 1991, Volume: 42, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cysteamine; Duodenal Ulcer; Female; Furazolidone; Indomethacin; Nitrofur

1991
[Comparative study of the effect of wei-yan-ning and furazolidone in the treatment of gastritis and gastric ulcer caused by pyloric Campylobacter].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1989, Volume: 9, Issue:10

    Topics: Adolescent; Adult; Campylobacter Infections; Chronic Disease; Drugs, Chinese Herbal; Duodenal Ulcer;

1989
[Effects of furazolidone on brain monoamines in the treatment of peptic ulcer].
    Zhonghua yi xue za zhi, 1989, Volume: 69, Issue:4

    Topics: Animals; Biogenic Monoamines; Brain; Cysteamine; Duodenal Ulcer; Female; Furazolidone; Rats; Rats, I

1989
[Effect of furazolidone on gut catecholamine levels in cysteamine-induced duodenal ulcer in the rat].
    Zhonghua nei ke za zhi, 1988, Volume: 27, Issue:5

    Topics: Animals; Catecholamines; Cysteamine; Duodenal Ulcer; Female; Furazolidone; Intestines; Rats; Rats, I

1988
Effect of furazolidone on gut catecholamine in cysteamine-induced duodenal ulcer in the rat.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:8

    Topics: Animals; Cysteamine; Dopamine; Dose-Response Relationship, Drug; Duodenal Ulcer; Duodenum; Female; F

1988