Page last updated: 2024-10-27

furazolidone and Cholera

furazolidone has been researched along with Cholera in 23 studies

Furazolidone: A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone acts by gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
furazolidone : A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera.

Cholera: An acute diarrheal disease endemic in India and Southeast Asia whose causative agent is VIBRIO CHOLERAE. This condition can lead to severe dehydration in a matter of hours unless quickly treated.

Research Excerpts

ExcerptRelevanceReference
"To test the efficacy and safety of furazolidone given as a single dose for childhood cholera, a randomized double-blind placebo-controlled trial was carried out among 118 culture-positive dehydrated children with diarrhea."9.07Efficacy of a single dose of furazolidone for treatment of cholera in children. ( Butler, T; Islam, MR; Mazumdar, R; Rabbani, GH; Shahrier, M, 1991)
"To evaluate single doses of 400 mg of furazolidone and 1 g of tetracycline given orally to patients with diarrhea due to Vibrio cholerae, we studied 87 adults in a randomized, double-blind, placebo-controlled trial."9.06Single-dose treatment of cholera with furazolidone or tetracycline in a double-blind randomized trial. ( Alam, K; Butler, T; Islam, MR; Rabbani, GH; Shahrier, M, 1989)
"A controlled comparison of furazolidone and tetracycline in the treatment of cholera indicates that, in either dosage used, furazolidone reduced total stool volume by 50% and duration of diarrhoea by 40%."9.03Controlled comparison of tetracycline and furazolidone in cholera. ( Banwell, JG; Caranasos, GJ; Keimowitz, RI; Mitra, RC; Mondal, A; Pierce, NF; Thomas, J, 1968)
"Tetracycline continues to be an effective antimicrobial agent in the clinical control of cholera but because of its high cost, relatively short shelf-life and recent reports of increased resistance of vibrios to tetracycline in vitro, alternative antimicrobial agents have been tested."7.65Furazolidone in paediatric cholera. ( Curlin, GT; Hirschhorn, N; Huq, MI; Karchmer, AW, 1970)
" cholera were as follows 76% [67,84] to furazolidone, 65% [29,94] to nitrofurantoin, 55% [44,66] to nalidixic acid, 10% [2,23] to rifampicin, 4%(0, 12) to novobiocin, 4% [2,6] to norfloxacin, 3% [1,4] to ciprofloxacin, 1%(0, 3) to sparofloxacin, 0%(0, 3) to levofloxacin, 0%(0, 2) to ofloxacin, 0%(0, 0) to gatifloxacin."5.22Globally Vibrio cholera antibiotics resistance to RNA and DNA effective antibiotics: A systematic review and meta-analysis. ( Ebrahimzadeh, F; Gholami, S; Jafari-Sales, A; Rostami, A; Zadeh, FA, 2022)
"To test the efficacy and safety of furazolidone given as a single dose for childhood cholera, a randomized double-blind placebo-controlled trial was carried out among 118 culture-positive dehydrated children with diarrhea."5.07Efficacy of a single dose of furazolidone for treatment of cholera in children. ( Butler, T; Islam, MR; Mazumdar, R; Rabbani, GH; Shahrier, M, 1991)
"To evaluate single doses of 400 mg of furazolidone and 1 g of tetracycline given orally to patients with diarrhea due to Vibrio cholerae, we studied 87 adults in a randomized, double-blind, placebo-controlled trial."5.06Single-dose treatment of cholera with furazolidone or tetracycline in a double-blind randomized trial. ( Alam, K; Butler, T; Islam, MR; Rabbani, GH; Shahrier, M, 1989)
"A controlled comparison of furazolidone and tetracycline in the treatment of cholera indicates that, in either dosage used, furazolidone reduced total stool volume by 50% and duration of diarrhoea by 40%."5.03Controlled comparison of tetracycline and furazolidone in cholera. ( Banwell, JG; Caranasos, GJ; Keimowitz, RI; Mitra, RC; Mondal, A; Pierce, NF; Thomas, J, 1968)
" Furazolidone (Furoxone) has been used for 30 years for the specific and symptomatic treatment of bacterial or protozoal diarrhoea and enteritis caused by susceptible organisms."4.77The use of furoxone: a perspective. ( Hailey, FJ; Phillips, KF, 1986)
" cholerae especially towards ciprofloxacin may significantly influence the control strategies in future outbreaks."3.75Epidemiology & antibiograms of Vibrio cholerae isolates from a tertiary care hospital in Chandigarh, north India. ( Chander, J; Deep, A; Gupta, V; Kaistha, N; Mehta, M; Sarkar, BL; Singla, N, 2009)
"Tetracycline continues to be an effective antimicrobial agent in the clinical control of cholera but because of its high cost, relatively short shelf-life and recent reports of increased resistance of vibrios to tetracycline in vitro, alternative antimicrobial agents have been tested."3.65Furazolidone in paediatric cholera. ( Curlin, GT; Hirschhorn, N; Huq, MI; Karchmer, AW, 1970)
"cholerae were obtained from water sources used by cholera cases due to resistant V."1.27Epidemiological differences between cholera due to multiple antibiotic resistant and multiple antibiotic sensitive Vibrio cholerae infection. ( Barua, DK; Begum, T; Khan, MU; Shahidullah, M, 1986)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199015 (65.22)18.7374
1990's2 (8.70)18.2507
2000's3 (13.04)29.6817
2010's1 (4.35)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Rostami, A1
Zadeh, FA1
Ebrahimzadeh, F1
Jafari-Sales, A1
Gholami, S1
Parvin, I1
Shahunja, KM1
Khan, SH1
Alam, T1
Shahrin, L1
Ackhter, MM1
Sarmin, M1
Dash, S1
Rahman, MW1
Shahid, ASMSB1
Golam Faruque, AS1
Ahmed, T1
Chisti, MJ1
Kingston, JJ1
Zachariah, K1
Tuteja, U1
Kumar, S1
Batra, HV1
Chander, J1
Kaistha, N1
Gupta, V1
Mehta, M1
Singla, N1
Deep, A1
Sarkar, BL1
Rashed, SM1
Mannan, SB1
Johura, FT1
Islam, MT1
Sadique, A1
Watanabe, H1
Sack, RB1
Huq, A1
Colwell, RR1
Cravioto, A1
Alam, M1
DUTTA, NK1
PANSE, MV1
Black, RE1
Niyogi, SK2
Sengupta, PG2
Bhattacharya, SK2
Garg, S1
Mukhapadhayay, AK1
Nair, GB1
Mazumdar, DN1
De, S1
De, SP1
Sircar, BK1
Frost, WH1
Anishchuk, VP1
Rabbani, GH2
Butler, T2
Shahrier, M2
Mazumdar, R1
Islam, MR2
Alam, K1
Phillips, KF1
Hailey, FJ1
Khan, MU1
Shahidullah, M1
Barua, DK1
Begum, T1
Chaudhuri, RN1
Neogy, KN1
Sanyal, SN1
Gupta, RK1
Manji, P1
Pierce, NF3
Banwell, JG2
Mitra, RC3
Caranasos, GJ1
Keimowitz, RI1
Thomas, J1
Mondal, A3
Gorbach, SL2
Carpenter, CC1
Hirschhorn, N2
Karchmer, AW1
Curlin, GT1
Huq, MI1
Banwell, JC1
Manji, PM1

Reviews

4 reviews available for furazolidone and Cholera

ArticleYear
Globally Vibrio cholera antibiotics resistance to RNA and DNA effective antibiotics: A systematic review and meta-analysis.
    Microbial pathogenesis, 2022, Volume: 172

    Topics: Anti-Bacterial Agents; Cephalothin; Cholera; Cholera Toxin; Ciprofloxacin; Drug Resistance, Bacteria

2022
The prophylaxis and therapy of secretory diarrhea.
    The Medical clinics of North America, 1982, Volume: 66, Issue:3

    Topics: Anti-Infective Agents, Urinary; Antidiarrheals; Chloramphenicol; Chlorpromazine; Cholera; Diarrhea;

1982
[The clinical course and treatment of cholera in children (review of the foreign literature)].
    Voprosy okhrany materinstva i detstva, 1975, Volume: 20, Issue:1

    Topics: Acid-Base Equilibrium; Acute Disease; Age Factors; Bicarbonates; Body Temperature; Child; Child, Pre

1975
The use of furoxone: a perspective.
    The Journal of international medical research, 1986, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Bacterial Vaccines; Carrier St

1986

Trials

5 trials available for furazolidone and Cholera

ArticleYear
Minocycline, tetracycline and furazolidone in the treatment of cholera.
    The Indian journal of medical research, 1977, Volume: 66, Issue:6

    Topics: Adult; Cholera; Furazolidone; Humans; Minocycline; Tetracycline; Tetracyclines

1977
Efficacy of a single dose of furazolidone for treatment of cholera in children.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:9

    Topics: Adolescent; Child; Child, Preschool; Cholera; Double-Blind Method; Female; Furazolidone; Humans; Inf

1991
Single-dose treatment of cholera with furazolidone or tetracycline in a double-blind randomized trial.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:9

    Topics: Adult; Cholera; Diarrhea; Double-Blind Method; Feces; Furazolidone; Humans; Randomized Controlled Tr

1989
Furazolidone in the treatment of cholera.
    Lancet (London, England), 1968, Feb-17, Volume: 1, Issue:7538

    Topics: Adult; Cholera; Furazolidone; Humans; Male; Tetracycline

1968
Controlled comparison of tetracycline and furazolidone in cholera.
    British medical journal, 1968, Aug-03, Volume: 3, Issue:5613

    Topics: Adult; Cholera; Clinical Trials as Topic; Diarrhea; Feces; Furazolidone; Humans; Male; Middle Aged;

1968

Other Studies

14 other studies available for furazolidone and Cholera

ArticleYear
Changing Susceptibility Pattern of
    The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Azithromycin; Bangladesh; Child; Cholera; Ciprofloxacin; Drug Resistan

2020
Molecular characterization of Vibrio cholerae isolates from cholera outbreaks in North India.
    Journal of microbiology (Seoul, Korea), 2009, Volume: 47, Issue:1

    Topics: Anti-Bacterial Agents; Cholera; Cloxacillin; Disease Outbreaks; DNA Fingerprinting; Endopeptidases;

2009
Epidemiology & antibiograms of Vibrio cholerae isolates from a tertiary care hospital in Chandigarh, north India.
    The Indian journal of medical research, 2009, Volume: 129, Issue:5

    Topics: Age Factors; Amoxicillin; Anti-Bacterial Agents; Cefotaxime; Cholera; Ciprofloxacin; Drug Resistance

2009
Genetic characteristics of drug-resistant Vibrio cholerae O1 causing endemic cholera in Dhaka, 2006-2011.
    Journal of medical microbiology, 2012, Volume: 61, Issue:Pt 12

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Typing Techniques; Bangladesh; Base Sequence;

2012
PAROMOMYCIN, POLYMYXIN B AND FURAZOLIDONE IN EXPERIMENTAL CHOLERA.
    Indian journal of physiology and pharmacology, 1964, Volume: 8

    Topics: Animals; Cholera; Furazolidone; Paromomycin; Pharmacology; Polymyxin B; Polymyxins; Rabbits; Researc

1964
Emergence of furazolidone and cotrimoxazole resistant Vibrio cholerae 01 in eastern India.
    The Journal of infection, 1995, Volume: 30, Issue:3

    Topics: Anti-Bacterial Agents; Cholera; Drug Resistance, Microbial; Furazolidone; Humans; India; Infant; Tri

1995
An outbreak of Eltor cholera in Aizwal town of Mizoram, India.
    The Journal of communicable diseases, 2000, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Cholera; Diarrhea; Disease Outbre

2000
Cholera: synopsis of clinical aspects and principles of treatment.
    Canadian Medical Association journal, 1976, Sep-04, Volume: 115, Issue:5

    Topics: Adult; Bicarbonates; Child; Chloramphenicol; Cholera; Dehydration; Female; Furazolidone; Humans; Lac

1976
Epidemiological differences between cholera due to multiple antibiotic resistant and multiple antibiotic sensitive Vibrio cholerae infection.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:1

    Topics: Anti-Bacterial Agents; Bangladesh; Cholera; Drug Resistance, Microbial; Furazolidone; Humans; Vibrio

1986
Convalescent carriers of Vibrio cholerae. Detection and detailed investigation.
    Annals of internal medicine, 1970, Volume: 72, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Agglutination Tests; Antibodies; Bacteriological Techniques; C

1970
Pediatric cholera: current concepts of therapy.
    The Journal of pediatrics, 1972, Volume: 80, Issue:5

    Topics: Administration, Oral; Age Factors; Bicarbonates; Child; Child, Preschool; Chlorides; Cholera; Choler

1972
Furazolidone in paediatric cholera.
    Bulletin of the World Health Organization, 1970, Volume: 43, Issue:3

    Topics: Antibody Formation; Body Weight; Child; Child, Preschool; Cholera; Diarrhea; Feces; Female; Furazoli

1970
Bacteriological studies of convalescent carriers of cholera vibrios.
    The Indian journal of medical research, 1969, Volume: 57, Issue:4

    Topics: Adult; Carrier State; Cholera; Furazolidone; Humans; Male; Tetracycline; Vibrio

1969
Chemotherapy and control of cholera.
    Bulletin of the Calcutta School of Tropical Medicine, 1966, Volume: 14, Issue:1

    Topics: Anti-Bacterial Agents; Cholera; Furazolidone; Humans

1966