Page last updated: 2024-10-27

furazolidone and Cardiomyopathies

furazolidone has been researched along with Cardiomyopathies in 19 studies

Furazolidone: A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone acts by gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
furazolidone : A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"Carvedilol is a non-selective beta-blocker with alpha-receptor blockade and antioxidant properties."5.32Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure. ( Doye, AA; Gwathmey, JK; Hajjar, RJ; Jabbour, G; Laste, N; Lebeche, D; Lee, MX; Okafor, CC; Perreault-Micale, C; Skiroman, K, 2003)
"We have previously demonstrated that in furazolidone-induced congestive heart failure in turkeys the specific Ca(2+)-ATPase activity of myocardial sarcoplasmic reticulum (SR) is 60% increased in compensation for a 50% depression in net Ca(2+)-sequestration activity."3.68Myocardial calcium cycling defect in furazolidone cardiomyopathy. ( Julian, RJ; Mirsalimi, SM; O'Brien, PJ; Shen, H; Weiler, JE, 1991)
"Carvedilol is a non-selective beta-blocker with alpha-receptor blockade and antioxidant properties."1.32Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure. ( Doye, AA; Gwathmey, JK; Hajjar, RJ; Jabbour, G; Laste, N; Lebeche, D; Lee, MX; Okafor, CC; Perreault-Micale, C; Skiroman, K, 2003)
"Newly hatched male White Pekin ducklings were fed furazolidone (FZ) at dosage of 750 mg/kg of feed for 4 weeks."1.27Furazolidone-induced congestive cardiomyopathy in ducklings: myocardial ultrastructural alterations. ( Ferrans, VJ; Van Vleet, JF, 1983)
"Furazolidone (700 ppm) was fed to turkey poults from 2 to 5 weeks of age."1.27Influence of thiamin supplements on furazolidone-induced cardiomyopathy in turkey poults. ( Ali, BH; Czarnecki, CM, 1987)
"1."1.26Role of taurine in furazolidone-induced cardiomyopathy. ( Czarnecki, CM; McClune, J; Schaffer, SW, 1982)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199017 (89.47)18.7374
1990's1 (5.26)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okafor, CC1
Perreault-Micale, C1
Hajjar, RJ1
Lebeche, D1
Skiroman, K1
Jabbour, G1
Doye, AA1
Lee, MX1
Laste, N1
Gwathmey, JK1
Schaffer, SW1
Czarnecki, CM10
McClune, J1
Evanson, OA3
Ali, BH3
Mustafa, AI1
Idris, SO1
Mahdi, BM1
Abu Elgasim, AI1
Powers, MD1
Good, AL1
Van Vleet, JF4
Ferrans, VJ4
Limas, CJ1
Einzig, S1
Noren, G1
Jegers, A1
Jankus, EF1
O'Brien, PJ1
Shen, H1
Weiler, JE1
Mirsalimi, SM1
Julian, RJ1

Reviews

3 reviews available for furazolidone and Cardiomyopathies

ArticleYear
Cardiomyopathy in turkeys.
    Comparative biochemistry and physiology. A, Comparative physiology, 1984, Volume: 77, Issue:4

    Topics: Aging; Animals; Blood Proteins; Calcium; Cardiomyopathies; Cortisone; Electrocardiography; Female; F

1984
Animal models of drug-induced cardiomyopathy.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:1

    Topics: Animals; Cardiomyopathies; Daunorubicin; Disease Models, Animal; Doxorubicin; Electrocardiography; E

1984
Some pharmacological and toxicological properties of furazolidone.
    Veterinary research communications, 1983, Volume: 6, Issue:1

    Topics: Adrenal Glands; Alcoholism; Animals; Anorexia; Brain; Cardiomyopathies; Cattle; Chick Embryo; Chicke

1983

Other Studies

16 other studies available for furazolidone and Cardiomyopathies

ArticleYear
Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure.
    BMC physiology, 2003, Jul-21, Volume: 3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Apoptosis; Carbazo

2003
Role of taurine in furazolidone-induced cardiomyopathy.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1982, Volume: 72, Issue:1

    Topics: Animals; Body Weight; Cardiomyopathies; Drinking; Electrocardiography; Furazolidone; Taurine; Turkey

1982
Myocardial calcium levels in furazolidone-induced cardiomyopathy in turkey poults.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 75, Issue:2

    Topics: Animals; Calcium; Cardiomyopathies; Furazolidone; Myocardium; Poultry Diseases; Turkeys

1983
Furazolidone poisoning associated with cardiomyopathy in chickens.
    The Veterinary record, 1984, Sep-08, Volume: 115, Issue:10

    Topics: Acute Disease; Animals; Cardiomyopathies; Chickens; Furazolidone; Poultry Diseases

1984
Monoamine oxidase inhibition and furazolidone-induced cardiomyopathy in turkey poults.
    Poultry science, 1983, Volume: 62, Issue:9

    Topics: Animals; Cardiomyopathies; Depression, Chemical; Diet; Electrocardiography; Furazolidone; Kidney; Li

1983
Congestive cardiomyopathy induced in ducklings fed graded amounts of furazolidone.
    American journal of veterinary research, 1983, Volume: 44, Issue:1

    Topics: Animals; Cardiomyopathies; Diet; Ducks; Food Additives; Furazolidone; Male; Myocardium; Poultry Dise

1983
Furazolidone-induced congestive cardiomyopathy in ducklings: regression of cardiac lesions after cessation of furazolidone ingestion.
    American journal of veterinary research, 1983, Volume: 44, Issue:6

    Topics: Animals; Cardiomyopathies; Disease Models, Animal; Ducks; Furazolidone; Heart Failure; Male; Myocard

1983
Furazolidone-induced congestive cardiomyopathy in ducklings: myocardial ultrastructural alterations.
    American journal of veterinary research, 1983, Volume: 44, Issue:6

    Topics: Animals; Cardiomyopathies; Ducks; Furazolidone; Heart Failure; Male; Myocardium; Myofibrils; Poultry

1983
Furazolidone-induced congestive cardiomyopathy in ducklings: lack of protection from selenium, vitamin E, and taurine supplements.
    American journal of veterinary research, 1983, Volume: 44, Issue:6

    Topics: Animals; Cardiomyopathies; Ducks; Furazolidone; Heart Failure; Male; Poultry Diseases; Selenium; Tau

1983
Contrasting effects of spontaneous and induced cardiomyopathy on the nucleoproteins of turkey hearts.
    Cardiovascular research, 1982, Volume: 16, Issue:5

    Topics: Animals; Cardiomyopathies; Cell Nucleus; Disease Models, Animal; Furazolidone; Hemodynamics; Myocard

1982
Distribution of myocardial glycogen in turkey poults during development of furazolidone-induced cardiomyopathy.
    Poultry science, 1980, Volume: 59, Issue:7

    Topics: Animals; Cardiomyopathies; Furazolidone; Glycogen; Myocardium; Poultry Diseases; Turkeys

1980
Characterization of glycogen in selected tissues of turkey poults with spontaneous round heart disease and furazolidone-induced cardiomyopathy.
    Acta anatomica, 1978, Volume: 102, Issue:1

    Topics: Animals; Cardiomyopathies; Furazolidone; Glucose; Glycogen; Glycogen Storage Disease; Glycogen Stora

1978
Myocardial calcium cycling defect in furazolidone cardiomyopathy.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:12

    Topics: Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cardiomyopathies; Disease Models,

1991
Influence of thiamin supplements on furazolidone-induced cardiomyopathy in turkey poults.
    Journal of comparative pathology, 1987, Volume: 97, Issue:4

    Topics: Animals; Body Weight; Cardiomyopathies; Eating; Electrocardiography; Furazolidone; Poultry Diseases;

1987
Quantitative morphological alterations during the development of furazolidone-induced cardiomyopathy in turkeys.
    Journal of comparative pathology, 1986, Volume: 96, Issue:1

    Topics: Age Factors; Animals; Body Weight; Cardiomyopathies; Cell Nucleus; Cytoplasm; Electrocardiography; F

1986
Changes in myocardial ultrastructure during development of furazolidone-induced cardiomyopathy in turkeys.
    Journal of comparative pathology, 1986, Volume: 96, Issue:1

    Topics: Age Factors; Animals; Cardiomyopathies; Furazolidone; Glycogen; Lipid Metabolism; Lysosomes; Microsc

1986