furazolidone has been researched along with Cancer of Liver in 2 studies
Furazolidone: A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone acts by gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
furazolidone : A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Furazolidone (FZD), a synthetic nitrofuran with a broad spectrum of antimicrobial actions, is known to induce genotoxicity and potential carcinogenicity in several types of cells, but little is known about its p38 mitogen-activation protein kinase (p38 MAPK) and c-Jun N-terminal protein kinase (JNK) pathways in human hepatoblastoma cell line (HepG2)." | 7.79 | Opposite effects of JNK and p38 MAPK signaling pathways on furazolidone-stimulated S phase cell cycle arrest of human hepatoblastoma cell line. ( Jin, X; Sun, Y; Tang, S; Xiao, X; Zhang, C; Zhao, W, 2013) |
| "Furazolidone (FZD), a synthetic nitrofuran with a broad spectrum of antimicrobial actions, is known to induce genotoxicity and potential carcinogenicity in several types of cells, but little is known about its p38 mitogen-activation protein kinase (p38 MAPK) and c-Jun N-terminal protein kinase (JNK) pathways in human hepatoblastoma cell line (HepG2)." | 3.79 | Opposite effects of JNK and p38 MAPK signaling pathways on furazolidone-stimulated S phase cell cycle arrest of human hepatoblastoma cell line. ( Jin, X; Sun, Y; Tang, S; Xiao, X; Zhang, C; Zhao, W, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, Y | 1 |
| Tang, S | 1 |
| Jin, X | 1 |
| Zhang, C | 1 |
| Zhao, W | 1 |
| Xiao, X | 1 |
| Auro, A | 1 |
| Sumano, H | 1 |
| Ocampo, L | 1 |
| Barragán, A | 1 |
2 other studies available for furazolidone and Cancer of Liver
| Article | Year |
|---|---|
Opposite effects of JNK and p38 MAPK signaling pathways on furazolidone-stimulated S phase cell cycle arrest of human hepatoblastoma cell line.
Topics: Antitrichomonal Agents; Apoptosis; Blotting, Western; Cell Cycle Checkpoints; Cell Proliferation; Fu | 2013 |
Evaluation of the carcinogenic effects of furazolidone and its metabolites in two fish species.
Topics: Animals; Carcinogenicity Tests; Drug Evaluation, Preclinical; Female; Furazolidone; Kidney Neoplasms | 2004 |