furan has been researched along with Acute Liver Injury, Drug-Induced in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 4 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Peng, Y; Tian, M; Zheng, J | 1 |
| Jiang, Y; Li, HJ; Li, P; Li, ZQ; Shi, W; Wang, LL; Wu, ZT | 1 |
| Ali, SA; Elbohi, KM; Emad, RM; Khalil, SR; Metwally, MMM; Salem, HFA | 1 |
| Nan, B; Wang, M; Wang, Z; Xi, C; Yan, H; Yang, C; Ye, H; Yuan, Y; Zhang, Y | 1 |
| Hong, Y; Wu, X; Yan, H; Yuan, Y; Zhang, X | 1 |
| Liu, X; Wu, SJ; Yuan, Y; Zhang, LL | 1 |
| Limbeck, E; Mally, A; Ramm, S | 1 |
| Burnett, M; Foley, J; Goldsworthy, TL; Maronpot, R; Moser, GJ | 1 |
| Chipman, JK; Evans, JG; Hammond, TG; Hickling, KC; Hitchcock, JM | 1 |
| Barker, M; Becalski, A; Bondy, G; Cooke, GM; Gill, S; Hou, Y; Kavanagh, M; Lefebvre, DE; Turcotte, AM; Vavasour, E; Weld, M | 1 |
| Dekant, W; Hamberger, C; Kellert, M; Mally, A; Schauer, UM | 1 |
1 review(s) available for furan and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Metabolic Activation and Hepatotoxicity of Furan-Containing Compounds.
Topics: Activation, Metabolic; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Furans; Humans | 2022 |
11 other study(ies) available for furan and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The crucial role of metabolic regulation in differential hepatotoxicity induced by furanoids in Dioscorea bulbifera.
Topics: Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cytochrome P-450 CYP3A; Dioscorea; Drugs, Chinese Herbal; Furans; Hep G2 Cells; Humans; Mass Spectrometry; Molecular Docking Simulation; Molecular Structure | 2020 |
Protective effect of Spirulina platensis against physiological, ultrastructural and cell proliferation damage induced by furan in kidney and liver of rat.
Topics: Animals; Biomarkers; Cell Proliferation; Chemical and Drug Induced Liver Injury; Furans; Ki-67 Antigen; Kidney; Kidney Diseases; Liver; Male; Proliferating Cell Nuclear Antigen; Rats; Spirulina | 2020 |
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress.
Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Furans; Glucosides; Inflammation; Liver; Male; Metabolomics; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phenols | 2021 |
Ameliorative effect of salidroside from Rhodiola Rosea L. on the gut microbiota subject to furan-induced liver injury in a mouse model.
Topics: Animals; Bacteria; Chemical and Drug Induced Liver Injury; Cytokines; DNA, Bacterial; DNA, Ribosomal; Dysbiosis; Furans; Gastrointestinal Microbiome; Glucosides; Inflammation; Lipopolysaccharides; Liver; Male; Mice, Inbred BALB C; Phenols; Proteobacteria; Rhodiola; Verrucomicrobia | 2019 |
Antioxidant effect of salidroside and its protective effect against furan-induced hepatocyte damage in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Furans; Glucosides; Glutathione Transferase; Hepatocytes; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidative Stress; Phenols; Reactive Oxygen Species; Thiobarbiturates; Transaminases | 2013 |
Functional and cellular consequences of covalent target protein modification by furan in rat liver.
Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Furans; Glycolysis; Liver; Male; Metabolic Networks and Pathways; Metabolomics; Protein Processing, Post-Translational; Proteins; Rats; Rats, Inbred F344; RNA, Messenger; Succinate Dehydrogenase | 2016 |
Furan-induced dose-response relationships for liver cytotoxicity, cell proliferation, and tumorigenicity (furan-induced liver tumorigenicity).
Topics: Animals; Cell Proliferation; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Furans; Liver; Liver Function Tests; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Necrosis | 2009 |
Induction and progression of cholangiofibrosis in rat liver injured by oral administration of furan.
Topics: Administration, Oral; Animals; Bile Ducts; Carcinogens; Cell Proliferation; Chemical and Drug Induced Liver Injury; Disease Progression; Epithelial Cells; Furans; Hepatocytes; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley | 2010 |
Subchronic oral toxicity study of furan in Fischer-344 rats.
Topics: Analysis of Variance; Animals; Biomarkers; Blood Platelets; Body Weight; Chemical and Drug Induced Liver Injury; Diet; Female; Furans; Histocytochemistry; Incidence; Liver; Liver Function Tests; Male; No-Observed-Adverse-Effect Level; Organ Size; Rats; Rats, Inbred F344; T-Lymphocytes | 2010 |
Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats.
Topics: Aldehydes; Animals; Bile; Bile Ducts; Biliary Tract Diseases; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Furans; Glutathione; Glycine; Male; Rats; Rats, Inbred F344; Tandem Mass Spectrometry | 2010 |