Page last updated: 2024-08-18

furan and Acute Liver Injury, Drug-Induced

furan has been researched along with Acute Liver Injury, Drug-Induced in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Peng, Y; Tian, M; Zheng, J1
Jiang, Y; Li, HJ; Li, P; Li, ZQ; Shi, W; Wang, LL; Wu, ZT1
Ali, SA; Elbohi, KM; Emad, RM; Khalil, SR; Metwally, MMM; Salem, HFA1
Nan, B; Wang, M; Wang, Z; Xi, C; Yan, H; Yang, C; Ye, H; Yuan, Y; Zhang, Y1
Hong, Y; Wu, X; Yan, H; Yuan, Y; Zhang, X1
Liu, X; Wu, SJ; Yuan, Y; Zhang, LL1
Limbeck, E; Mally, A; Ramm, S1
Burnett, M; Foley, J; Goldsworthy, TL; Maronpot, R; Moser, GJ1
Chipman, JK; Evans, JG; Hammond, TG; Hickling, KC; Hitchcock, JM1
Barker, M; Becalski, A; Bondy, G; Cooke, GM; Gill, S; Hou, Y; Kavanagh, M; Lefebvre, DE; Turcotte, AM; Vavasour, E; Weld, M1
Dekant, W; Hamberger, C; Kellert, M; Mally, A; Schauer, UM1

Reviews

1 review(s) available for furan and Acute Liver Injury, Drug-Induced

ArticleYear
Metabolic Activation and Hepatotoxicity of Furan-Containing Compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2022, Volume: 50, Issue:5

    Topics: Activation, Metabolic; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Furans; Humans

2022

Other Studies

11 other study(ies) available for furan and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The crucial role of metabolic regulation in differential hepatotoxicity induced by furanoids in Dioscorea bulbifera.
    Chinese journal of natural medicines, 2020, Volume: 18, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cytochrome P-450 CYP3A; Dioscorea; Drugs, Chinese Herbal; Furans; Hep G2 Cells; Humans; Mass Spectrometry; Molecular Docking Simulation; Molecular Structure

2020
Protective effect of Spirulina platensis against physiological, ultrastructural and cell proliferation damage induced by furan in kidney and liver of rat.
    Ecotoxicology and environmental safety, 2020, Apr-01, Volume: 192

    Topics: Animals; Biomarkers; Cell Proliferation; Chemical and Drug Induced Liver Injury; Furans; Ki-67 Antigen; Kidney; Kidney Diseases; Liver; Male; Proliferating Cell Nuclear Antigen; Rats; Spirulina

2020
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress.
    Toxicology, 2021, Volume: 461

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Furans; Glucosides; Inflammation; Liver; Male; Metabolomics; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phenols

2021
Ameliorative effect of salidroside from Rhodiola Rosea L. on the gut microbiota subject to furan-induced liver injury in a mouse model.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 125

    Topics: Animals; Bacteria; Chemical and Drug Induced Liver Injury; Cytokines; DNA, Bacterial; DNA, Ribosomal; Dysbiosis; Furans; Gastrointestinal Microbiome; Glucosides; Inflammation; Lipopolysaccharides; Liver; Male; Mice, Inbred BALB C; Phenols; Proteobacteria; Rhodiola; Verrucomicrobia

2019
Antioxidant effect of salidroside and its protective effect against furan-induced hepatocyte damage in mice.
    Food & function, 2013, Apr-30, Volume: 4, Issue:5

    Topics: Alanine Transaminase; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Furans; Glucosides; Glutathione Transferase; Hepatocytes; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidative Stress; Phenols; Reactive Oxygen Species; Thiobarbiturates; Transaminases

2013
Functional and cellular consequences of covalent target protein modification by furan in rat liver.
    Toxicology, 2016, 06-15, Volume: 361-362

    Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Furans; Glycolysis; Liver; Male; Metabolic Networks and Pathways; Metabolomics; Protein Processing, Post-Translational; Proteins; Rats; Rats, Inbred F344; RNA, Messenger; Succinate Dehydrogenase

2016
Furan-induced dose-response relationships for liver cytotoxicity, cell proliferation, and tumorigenicity (furan-induced liver tumorigenicity).
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2009, Volume: 61, Issue:2

    Topics: Animals; Cell Proliferation; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Furans; Liver; Liver Function Tests; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Necrosis

2009
Induction and progression of cholangiofibrosis in rat liver injured by oral administration of furan.
    Toxicologic pathology, 2010, Volume: 38, Issue:2

    Topics: Administration, Oral; Animals; Bile Ducts; Carcinogens; Cell Proliferation; Chemical and Drug Induced Liver Injury; Disease Progression; Epithelial Cells; Furans; Hepatocytes; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley

2010
Subchronic oral toxicity study of furan in Fischer-344 rats.
    Toxicologic pathology, 2010, Volume: 38, Issue:4

    Topics: Analysis of Variance; Animals; Biomarkers; Blood Platelets; Body Weight; Chemical and Drug Induced Liver Injury; Diet; Female; Furans; Histocytochemistry; Incidence; Liver; Liver Function Tests; Male; No-Observed-Adverse-Effect Level; Organ Size; Rats; Rats, Inbred F344; T-Lymphocytes

2010
Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:10

    Topics: Aldehydes; Animals; Bile; Bile Ducts; Biliary Tract Diseases; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Furans; Glutathione; Glycine; Male; Rats; Rats, Inbred F344; Tandem Mass Spectrometry

2010