Page last updated: 2024-09-03

furamidine and Trypanosomiasis, African

furamidine has been researched along with Trypanosomiasis, African in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (5.88)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (58.82)	29.6817
2010's	6 (35.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boykin, DW; Brun, R; Easterbrook, JD; Ismail, MA; Tanious, FA; Wilson, WD	1
Anbazhagan, M; Ansede, JH; Boykin, DW; Brun, R; Easterbrook, JD; Hall, JE	1
Arafa, RK; Boykin, DW; Brun, R; Stephens, CE; Tanious, FA; Wenzler, T; Wilson, WD	1
Lanteri, CA; Meshnick, SR; Tidwell, RR	1
Bakunov, SA; Bakunova, SM; Barzcz, T; Brun, R; Chen, H; Jones, SK; Kumar, EV; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Boykin, DW; Brun, R; Hall, JE; Ismail, MA; Tidwell, RR; Wenzler, T	1
Arafa, RK; Boykin, DW; Brun, R; Hu, L; Ismail, MA; Munde, M; Patel, A; Wenzler, T; Wilson, WD	1
Boykin, DW; Branowska, D; Brun, R; Farahat, AA; Kumar, A; Liu, Y; Wenzler, T; Wilson, WD	1
Bialy, SA; Boykin, DW; Brun, R; Ismail, MA; Nanjunda, R; Wenzler, T; Wilson, WD	1
Bondada, L; Boykin, DW; Brun, R; Hu, L; Munde, M; Patel, A; Wang, MZ; Wenzler, T; Wilson, WD; Yang, S	1
Bakunov, SA; Bakunova, SM; Brun, R; Patrick, DA; Tidwell, RR; Wenzler, T	1
Boykin, DW; Brun, R; Miller, PN; Wang, MZ; Wenzler, T; Wu, H; Yang, S	1
Brun, R; Kagira, JM; Karanja, SM; Mdachi, RE; Ngotho, JM; Thuita, JK; Tidwell, R; Wenzler, T	1
Generaux, CN; Goldsmith, RB; Gray, DR; Reisner, HM; Tidwell, RR; Yan, Z	1
Bagnell, CR; Brock, JL; Hall, JE; Sturk, LM; Tidwell, RR	1
Werbovetz, K	1
Davidson, DE; Duxbury, RE; Johnson, AJ; Kinnamon, KE; Masters, RE; Steck, EA	1

Reviews

1 review(s) available for furamidine and Trypanosomiasis, African

Article	Year
Diamidines as antitrypanosomal, antileishmanial and antimalarial agents. Current opinion in investigational drugs (London, England : 2000), 2006, Volume: 7, Issue:2 Topics: Animals; Antimalarials; Antiprotozoal Agents; Benzamidines; Chagas Disease; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Leishmania; Leishmaniasis; Malaria, Falciparum; Pentamidine; Plasmodium falciparum; Prodrugs; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma cruzi; Trypanosomiasis, African	2006

Article

Year

Diamidines as antitrypanosomal, antileishmanial and antimalarial agents.

Current opinion in investigational drugs (London, England : 2000), 2006, Volume: 7, Issue:2

Topics: Animals; Antimalarials; Antiprotozoal Agents; Benzamidines; Chagas Disease; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Leishmania; Leishmaniasis; Malaria, Falciparum; Pentamidine; Plasmodium falciparum; Prodrugs; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma cruzi; Trypanosomiasis, African

2006

Other Studies

16 other study(ies) available for furamidine and Trypanosomiasis, African

Article	Year
Synthesis and antiprotozoal activity of aza-analogues of furamidine. Journal of medicinal chemistry, 2003, Oct-23, Volume: 46, Issue:22 Topics: Animals; Antimalarials; Antiprotozoal Agents; Aza Compounds; Benzamidines; Mice; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2003
O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection. Journal of medicinal chemistry, 2004, Aug-12, Volume: 47, Issue:17 Topics: Administration, Oral; Animals; Benzamidines; Biological Transport; Caco-2 Cells; Disease Models, Animal; Humans; In Vitro Techniques; Mice; Microsomes, Liver; Permeability; Prodrugs; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2004
Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs. Journal of medicinal chemistry, 2005, Aug-25, Volume: 48, Issue:17 Topics: Animals; Antiprotozoal Agents; Carbamates; Cations; Circular Dichroism; DNA; Fluorenes; Guanidines; Mice; Plasmodium falciparum; Poly dA-dT; Prodrugs; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2005
The mitochondrion is a site of trypanocidal action of the aromatic diamidine DB75 in bloodstream forms of Trypanosoma brucei. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Animals; Benzamidines; Blood; Flow Cytometry; Fluorescent Dyes; Membrane Potentials; Mice; Mitochondria; Oxygen Consumption; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Rhodamine 123; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2008
Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Animals; Antiprotozoal Agents; Benzene; Cell Survival; Leishmania donovani; Mice; Myoblasts; Naphthalenes; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
New treatment option for second-stage African sleeping sickness: in vitro and in vivo efficacy of aza analogs of DB289. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10 Topics: Animals; Benzamidines; Central Nervous System; Female; Furans; Mice; Molecular Structure; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum. Bioorganic & medicinal chemistry, 2009, Sep-15, Volume: 17, Issue:18 Topics: Animals; Antiprotozoal Agents; Inhibitory Concentration 50; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles. Bioorganic & medicinal chemistry, 2010, May-15, Volume: 18, Issue:10 Topics: Administration, Oral; Animals; Antimalarials; Antiprotozoal Agents; Disease Models, Animal; DNA, Protozoan; Drug Stability; Malaria, Falciparum; Mice; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Rats; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2010
Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents. Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2 Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Mice; Pentamidine; Plasmodium falciparum; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2011
Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues. Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21 Topics: Animals; Antiprotozoal Agents; Aza Compounds; Cations; Cell Line; Cell Survival; Disease Models, Animal; Mice; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Plasmodium falciparum; Poly dA-dT; Prodrugs; Pyrazines; Rats; Structure-Activity Relationship; Transition Temperature; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2013
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Animals; Antiprotozoal Agents; Isoxazoles; Mice; Molecular Structure; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Trypanosomiasis, African	2014
Pharmacokinetic comparison to determine the mechanisms underlying the differential efficacies of cationic diamidines against first- and second-stage human African trypanosomiasis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:7 Topics: Amidines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamidines; Blood-Brain Barrier; Cell Line; Dogs; Furans; Madin Darby Canine Kidney Cells; Male; Mice; Pentamidine; Protein Binding; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2014
Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis. Acta tropica, 2008, Volume: 108, Issue:1 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Benzamidines; Female; Humans; Mice; Molecular Structure; Pentamidine; Prodrugs; Trypanosoma brucei gambiense; Trypanosomiasis, African	2008
Application of monoclonal antibodies to measure metabolism of an anti-trypanosomal compound in vitro and in vivo. Journal of clinical laboratory analysis, 2010, Volume: 24, Issue:3 Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Benzamidines; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Female; Hepatocytes; Humans; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Pentamidine; Prodrugs; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tandem Mass Spectrometry; Trypanocidal Agents; Trypanosomiasis, African	2010
Distribution and quantitation of the anti-trypanosomal diamidine 2,5-bis(4-amidinophenyl)furan (DB75) and its N-methoxy prodrug DB289 in murine brain tissue. Acta tropica, 2004, Volume: 91, Issue:2 Topics: Administration, Oral; Animals; Benzamidines; Blood-Brain Barrier; Brain; Injections, Intravenous; Male; Mice; Microscopy, Fluorescence; Prodrugs; Tissue Distribution; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African	2004
Trypanosoma rhodesiense: evaluation of the antitrypanosomal action of 2,5-bis(4-guanylphenyl)furan dihydrochloride. Experimental parasitology, 1982, Volume: 53, Issue:1 Topics: Amidines; Animals; Benzamidines; Female; Macaca mulatta; Male; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1982