furaltadon and Hypersensitivity

Topics: Animals; Cell Degranulation; Cell Line; Cytokines; Gene Expression Regulation; Hypersensitivity; Immunoglobulin E; Male; Mast Cells; Mice; Mice, Inbred BALB C; Nitrofurans; Oxazolidinones; Passive Cutaneous Anaphylaxis; Signal Transduction; src-Family Kinases; Syk Kinase

Studies were carried out on the effect of furazolidon, spectam, Esb-3 and altabactin on the production of agglutinins and the initiation and development of an allergic response in chickens affected with pullorum disease. It was found that these preparations, when used three times at intervals of 20 days, in the course of 10 days each time at the respective therapeutic rates led to the decrease in the titer of agglutinins in the treated birds as early as the tenth day from the beginning of treatment. This trend remained unchanged during the whole period of treatment. Under the same experimental conditions no inhibition of the allergic reaction in the diseased birds against the lipopolysaccharide allergen of Salmonella gallinarum-pullorum was established.

Topics: Agglutination Tests; Animals; Antibodies, Bacterial; Chickens; Furazolidone; Hypersensitivity; Nitrofurans; Oxazolidinones; Poultry Diseases; Salmonella Infections, Animal; Spectinomycin; Sulfachlorpyridazine; Time Factors

Topics: Hypersensitivity; Immune System Diseases; Medical Records; Nitrofurans; Oxazolidinones