furaltadon and Chronic-Disease

Prolonged administration of furazolidone to calves may give rise to chronic furazolidone poisoning: retardation of growth, thrombocytopenia and leucopenia, occasionally changing into haemorrhagic diathesis. In acute nitrofuran poisoning neurological signs are observed as a consequence of monoamine oxidase inhibition. Five incidents of acute nitrofuran poisoning on veal calf farms are reported in the present paper, each with a mortality rate varying frm 46.7 per cent ot 70 per cent. Ten times the recommended dose of furazolidone or furadoltone was administered in each case.

Topics: Acute Disease; Animals; Cattle; Cattle Diseases; Chronic Disease; Furazolidone; Nitrofurans; Oxazolidinones

A study was carried out on the influence of the treatment with furasolidon and altabactin, alone and in combination with spectam and Esb3, in naturally infected and chronically suffering from typhus-puporosis fowls. It was proved that the treatment leads to a clinical but not to a epizootological recovery. It was also proved that the treatment of fowls against typhus-pulorosis, did not have any effect on the sensitivity, the specificity and the detectability of the allergic reaction, whereas the diagnostic value of the serological reaction always diminished. With all the fowls treated, characteristic pathohistological changes were detected, typical of typhus-pulorosis, which make more complete the results of the serological, the allergic and the bacteriological studies, and contributed to the detection of chronically ill fowls.

Topics: Animal Feed; Animals; Chickens; Chronic Disease; Female; Furazolidone; Liver; Lung; Myocardium; Nitrofurans; Oxazoles; Oxazolidinones; Poultry Diseases; Salmonella Infections, Animal; Spectinomycin