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furaldehyde and Anemia, Sickle Cell

furaldehyde has been researched along with Anemia, Sickle Cell in 8 studies

*Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S. [MeSH]

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdulmalik, O; Abraham, DJ; Asakura, T; Burnett, JC; Danso-Danquah, R; Joshi, GS; Musayev, FN; Nokuri, S; Safo, MK1
Abdulmalik, O; Alabbas, AB; Chen, Q; David, T; Gazi, A; Ghatge, MS; Musayev, FN; Pagare, PP; Safo, MK; Safo, RP; Venitz, J; Xu, GG; Zhang, Y1
Kato, GJ; Safo, MK1
Cytlak, UM; Gibson, JS; Hannemann, A; Rees, DC; Tewari, S1
Humphries, C1
Boutom, S; Cellmer, T; Christoph, GW; Dunkelberger, EB; Eaton, WA; Henry, ER; Hofrichter, J; Hsieh, MM; Jones-Straehle, S; Li, Q; Link, ME; Metaferia, BB; Miller, JL; Smith, JF; Staton, D; Tisdale, JF; Vass, ER; Wakefield, TH1
Abdulmalik, O; Abraham, DJ; Asakura, T; Brugnara, C; Chen, Q; Ohene-Frempong, K; Safo, MK; Yang, J1
Hsu, C; Itokawa, H; Lee, KH; Lin, AS; Lin, L; Morris-Natschke, SL; Qian, K; Usami, Y1

Reviews

1 review(s) available for furaldehyde and Anemia, Sickle Cell

ArticleYear
Therapeutic strategies to alter the oxygen affinity of sickle hemoglobin.
    Hematology/oncology clinics of North America, 2014, Volume: 28, Issue:2

    Topics: Anemia, Sickle Cell; Animals; Antisickling Agents; Binding, Competitive; Furaldehyde; Hemoglobin, Sickle; Humans; Mice; Oxygen; Protein Binding

2014

Other Studies

7 other study(ies) available for furaldehyde and Anemia, Sickle Cell

ArticleYear
Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds.
    Journal of medicinal chemistry, 2004, Sep-09, Volume: 47, Issue:19

    Topics: Aldehydes; Anemia, Sickle Cell; Antisickling Agents; Binding Sites; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Cyclization; Furans; Hemoglobin, Sickle; Homozygote; Humans; Models, Molecular; Molecular Structure; Oxygen; Protein Structure, Tertiary; Structure-Activity Relationship

2004
Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease.
    Molecular pharmaceutics, 2017, 10-02, Volume: 14, Issue:10

    Topics: Anemia, Sickle Cell; Antisickling Agents; Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Drug Design; Erythrocytes; Esters; Ethers; Furaldehyde; Healthy Volunteers; Hemoglobin, Sickle; Humans; Models, Molecular; Oxygen; Protein Binding; Structure-Activity Relationship; Time Factors; Treatment Outcome

2017
Effects of 5-hydroxymethyl-2-furfural on the volume and membrane permeability of red blood cells from patients with sickle cell disease.
    The Journal of physiology, 2014, Sep-15, Volume: 592, Issue:18

    Topics: Anemia, Sickle Cell; Calcium; Cell Membrane; Cell Size; Cells, Cultured; Erythrocytes; Furaldehyde; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; K Cl- Cotransporters; Permeability; Phosphatidylserines; Potassium; Symporters

2014
Drug development: a complicated path.
    Nature, 2014, Nov-13, Volume: 515, Issue:7526

    Topics: Anemia, Sickle Cell; Biomedical Research; Bone Marrow Transplantation; Drug Discovery; Drug Industry; Furaldehyde; Hemoglobin, Sickle; Humans; Poloxamer

2014
Kinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 01-31, Volume: 114, Issue:5

    Topics: Anemia, Sickle Cell; Antisickling Agents; Cell Size; Erythrocytes; Furaldehyde; Hemoglobin, Sickle; Humans; Kinetics; Oxygen

2017
5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells.
    British journal of haematology, 2005, Volume: 128, Issue:4

    Topics: Anemia, Sickle Cell; Animals; Antisickling Agents; Biological Availability; Cells, Cultured; Dose-Response Relationship, Drug; Erythrocytes; Furaldehyde; Hemoglobin, Sickle; Hypoxia; Ligands; Mice; Mice, Transgenic; Models, Molecular; Oxygen Consumption; Survival Analysis

2005
5-Hydroxymethyl-2-furfural, a clinical trials agent for sickle cell anemia, and its mono/di-glucosides from classically processed steamed Rehmanniae Radix.
    Journal of natural medicines, 2008, Volume: 62, Issue:2

    Topics: Anemia, Sickle Cell; Chromatography, High Pressure Liquid; Disaccharides; Drugs, Chinese Herbal; Furaldehyde; Furans; Glucosides; Hot Temperature; Humans; Plant Roots; Rehmannia

2008