fumaric-acid has been researched along with Salmonella-Infections--Animal* in 2 studies
2 other study(ies) available for fumaric-acid and Salmonella-Infections--Animal
Article | Year |
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Effect of organic acids and mannanoligosaccharide on excretion of Salmonella typhimurium in experimentally infected growing pigs.
The effect of organic acids and mannanoligosaccharide addition to the diet was assessed in pigs orally inoculated with Salmonella typhimurium. Forty-six growers were distributed among four treatments: Basal Diet (BD); BD+encapsulated organic acids; BD+free organic acids; BD+mannanoligosaccharide. Seroconversion was monitored, and feces and tissue samples were tested for Salmonella isolation. No treatment prevented the carrier state, but a tendency of lower fecal excretion was observed in the group treated with mannanoligosaccharide. Topics: Animals; Carrier State; Citric Acid; Diet; Dietary Supplements; Feces; Formates; Fumarates; Malates; Mannans; Oligosaccharides; Phosphoric Acids; Propionates; Salmonella Infections, Animal; Salmonella typhimurium; Swine; Swine Diseases | 2012 |
Genes responsible for anaerobic fumarate and arginine metabolism are involved in growth suppression in Salmonella enterica serovar Typhimurium in vitro, without influencing colonisation inhibition in the chicken in vivo.
From a collection of over 2800 Salmonella enterica subspecies Enterica serotype Typhimurium F98 Tn5-TC1 insertion mutants 14 were identified as expressing growth-non-suppressive phenotype under strict anaerobic conditions. Sequence analysis of regions flanking the Tn insertions revealed that most of the selected mutants were defective in genes contributing to the anaerobic fumarate uptake and generation (insertions in dcuA, dcuB and aspA), or to the anaerobic L-arginine utilisation pathway (insertions in STM4467 encoding a putative arginine deiminase, and in between speF encoding ornithine decarboxylase and kdpE coding a response regulator protein). Mutants defective in flagellum synthesis (flhA) were also identified. In contrast to the in vitro results, all the mutants colonised 1-day-old chicks efficiently and suppressed the super-infection of chicks by the parent strain. This clearly indicates that neither of the metabolic pathways mentioned above nor motility play essential roles in lower intestinal tract colonisation. Topics: Anaerobiosis; Animals; Arginine; Chickens; Colony Count, Microbial; Flagella; Fumarates; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genotype; Intestines; Male; Mutagenesis, Insertional; Poultry Diseases; Salmonella Infections, Animal; Salmonella typhimurium; Specific Pathogen-Free Organisms | 2003 |