fumarates and Erythema

For the first time in Argentina, we describe an outbreak of contact dermatitis. New pairs of shoes caused intense pruritus, pain, and eruption, followed by edema, blisters, and a severe negative impact on the epidermal barrier of the feet. We identify dimethylfumarate as the causal agent and suggest an analytical method for its fast identification.

Topics: Adult; Animals; Anti-Bacterial Agents; Argentina; Blister; Dermatitis, Contact; Dimethyl Fumarate; Epidemics; Erythema; Female; Foot; Fumarates; Fungicides, Industrial; Gentamicins; Humans; Hypersensitivity; Miconazole; Patch Tests; Pruritus; Rabbits; Shoes

Topics: Adult; Blister; Edema; Erythema; Fumarates; Humans; Irritants; Male; Nitriles; Pruritus; Skin Diseases; Water

Topics: Appetite Depressants; Blood Pressure; Central Nervous System; Chlorpromazine; Diazepam; Erythema; Fumarates; Gastric Lavage; Humans; Ipecac; Oxazoles; Phenobarbital; Psychomotor Disorders; Pupil; Respiration; Tachycardia