fumarates and Dermatitis

fumarates has been researched along with Dermatitis* in 3 studies

Other Studies

3 other study(ies) available for fumarates and Dermatitis

ArticleYear
Off-label use of fumarate therapy for granulomatous and inflammatory skin diseases other than psoriasis vulgaris: a retrospective study.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2012, Volume: 26, Issue:11

    Fumarates are approved for the systemic treatment of moderate and severe psoriasis vulgaris in Germany. However, a number of studies and case reports indicate their efficacy in the treatment of further inflammatory skin disorders or granulomatous skin diseases.. To examine the efficacy and safety of fumarates for the treatment of granulomatous and inflammatory skin diseases other than psoriasis vulgaris.. The therapeutic efficacy and side-effects of fumarate therapy were analysed retrospectively in patients with granuloma annulare (GA, n = 4), cutaneous sarcoidosis (SA, n = 1), lichen planus (LP, n = 3), pityriasis rubra pilaris (PRP, n = 1) or chronic discoid lupus erythematosus (CDLE, n = 1).. Six patients (GA: 3/4; LP: 2/3; PRP: 1/1) showed complete clearance and two patients (GA: 1/3; SA: 1/1) had a partial response, and the CDLE patient showed stable disease under a combination therapy with hydroxychloroquine. Side-effects associated with fumarate therapy were seen in seven of ten patients and resolved spontaneously upon dose reduction or discontinuation of the therapy.. According to this data, fumarates may represent a new approach in the treatment of granulomatous and inflammatory skin diseases other than psoriasis vulgaris. For the first time, the successful treatment of LP and CDLE with fumarates is reported. Side-effects are not limiting in most cases, but can hamper a dose escalation.

    Topics: Adolescent; Adult; Aged; Dermatitis; Female; Fumarates; Granuloma; Humans; Male; Middle Aged; Off-Label Use; Psoriasis; Retrospective Studies; Treatment Outcome

2012
[Cutaneous and pulmonary sarcoidosis. Successful therapy with fumaric acid esters].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2012, Volume: 63, Issue:10

    A 43-year-old man with cutaneous and pulmonary sarcoidosis was treated with fumaric acid esters (Fumaderm®) for 11 months because of the cutaneous lesions. During the treatment the cutaneous lesions and pulmonary changes vanished completely. In addition, serum angiotensin converting enzyme (ACE) levels normalized after end of therapy. This case report is one of a few examples of the successful treatment of cutaneous and pulmonary sarcoidosis with fumaric acid esters (Fumaderm®).

    Topics: Adult; Dermatitis; Dimethyl Fumarate; Fumarates; Humans; Male; Sarcoidosis; Sarcoidosis, Pulmonary; Treatment Outcome

2012
[Lichenoid dermatitis resulting from sensitization to dimethylfumarate: atypical presentation of "Chinese sofa dermatitis"].
    Annales de dermatologie et de venereologie, 2009, Volume: 136, Issue:3

    Topics: Dermatitis; Dimethyl Fumarate; Fumarates; Immunization; Lichenoid Eruptions; Lichens

2009