Page last updated: 2024-08-26

fulvestrant and Local Neoplasm Recurrence

fulvestrant has been researched along with Local Neoplasm Recurrence in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (11.32)29.6817
2010's21 (39.62)24.3611
2020's26 (49.06)2.80

Authors

AuthorsStudies
Asakawa, H; Baba, N; Nakamura, A; Park, K; Shigekawa, T1
Abdulkareem, NM; Bae, L; Bhat, R; Cataldo, ML; De Angelis, C; Fu, X; Nanda, S; Schiff, R; Thangavel, H; Trivedi, MV; Vasaikar, S; Zhang, B1
Anan, K; Aogi, K; Fujisawa, T; Hasegawa, Y; Hattori, M; Ito, Y; Kawaguchi, H; Masuda, N; Morita, S; Nakamura, S; Nakayama, T; Ohno, S; Ohtani, S; Saji, S; Sato, N; Takano, T; Toi, M; Tokunaga, E; Yamaguchi, M; Yamamoto, Y; Yamashita, H; Yamashita, T; Yotsumoto, D2
Higashi, T; Mase, K; Mizutani, M; Moriya, T; Ozawa, K; Takagi, S; Takei, S; Takeshita, A; Yokoyama, M1
Aithal, KB; Albacker, LA; Banka, D; Bolduc, DM; Furman, C; Hao, MH; Irwin, S; Kim, A; Korpal, M; Larsen, N; Montesion, M; Moriarty, AD; Murugesan, K; Nguyen, TV; Prajapati, S; Puyang, X; Rimkunas, V; Sahmoud, T; Vaillancourt, FH; Wick, MJ; Wu, ZJ; Yao, S; Zeng, H; Zhang, X; Zhang, Z; Zheng, GZ; Zhu, P1
Bale, C; Bezecny, P; Butler, R; Carucci, M; Casbard, A; de Bruin, EC; Foxley, A; Howell, SJ; Ingarfield, K; Jones, RH; Meissner, M; Moon, S; Morgan, S; Schiavon, G; Twelves, C; Venkitaraman, R; Waters, S1
Lauchle, JO; Metcalfe, C1
Belka, GK; Chen, S; Chodosh, LA; DeMichele, A; Makhlin, I; Mesaros, C; Pan, TC; Pant, DK; Paul, MR; Sreekumar, A; Sterner, CJ; Wang, D; Xu, P1
Alexis, MN; Chatziioannou, A; Ganou, V; Gkotsi, EF; Meligova, AK; Mitsiou, DJ; Papadodima, O; Pilalis, E; Siakouli, D; Stasinopoulou, S; Xenopoulou, DS; Zoumpouli, M1
Cortes, J; Dalenc, F; de Bruin, EC; Foxley, A; Gomez Moreno, HL; Grinsted, L; Howell, SJ; Hu, X; Jhaveri, K; Krivorotko, P; Loibl, S; Morales Murillo, S; Okera, M; Oliveira, M; Park, YH; Rugo, HS; Schiavon, G; Sohn, J; Toi, M; Tokunaga, E; Turner, NC; Yousef, S; Zhukova, L1
Olufade, T; Schwartzberg, LS; Skinner, KE; Walker, MS1
Bun, A; Fujimoto, Y; Fukui, R; Higuchi, T; Imamura, M; Miyagawa, Y; Miyoshi, Y; Ozawa, H; Sata, A1
Almotlak, AA; Farooqui, M; Siegfried, JM1
Brufsky, AM; Nasrazadani, A1
Alchami, F; Bale, C; Bezecny, P; Butler, R; Carucci, M; Casbard, A; Cox, C; Foxley, A; Howell, SJ; Joffe, J; Jones, RH; Madden, TA; Moon, S; Twelves, C; Venkitaraman, R; Waters, S1
Jiang, YZ; Liu, XY; Shao, ZM; Wang, H1
Dekker, TJA1
Kim, DH; Ludmir, EB; McCaw, ZR; Tian, L; Wei, LJ1
Carucci, M; Casbard, A; Foxley, A; Howell, SJ; Jones, RH1
Cao, Y; Ding, J; Fu, W; Guo, Y; Jiang, X; Li, K1
Li, Z; Liu, Z; Shao, Z; Song, C; Wang, X; Xiao, Z; Yang, X; Zhang, K1
Cortés, J; Cui, N; De Laurentiis, M; Dent, S; Diéras, V; Drullinsky, P; Harbeck, N; He, J; Hsu, JY; Im, YH; Jacot, W; Krop, IE; Schimmoller, F; Sousa, S; Wilson, TR1
Aja, J; Brantley, E; Campbell, P; Davis, MB; Loaiza-Perez, A; Mavingire, N; Wooten, J1
Ortmann, O; Riedmeier, M; Schüler-Toprak, S; Skrzypczak, M; Treeck, O1
Akiyama, Y; Doi, S; Hagihara, K; Matsushita, K; Motoki, Y; Nakaguchi, K; Sakisaka, H1
Abe, M; Chiba, R; Ishiguro, A; Ito, K; Kato, H; Kubota, R; Matsunami, O; Narita, Y; Ohigashi, A; Tanimoto, A1
Anan, K; Aogi, K; Fujisawa, T; Hasegawa, Y; Hattori, M; Ito, Y; Kawaguchi, H; Masuda, N; Morita, S; Nakamura, S; Nakayama, T; Ohno, S; Ohtani, S; Saji, S; Sato, N; Toi, M; Tokunaga, E; Yamaguchi, M; Yamamoto, Y; Yamashita, T1
Akiyoshi, S; Ijichi, H; Ishida, M; Koga, C; Koi, Y; Masuda, T; Nakamura, Y; Ohno, S; Tokunaga, E1
Aktas, B; Barry, WT; Carey, LA; Carrasco, E; Casas, M; Cirrincione, CT; De la Haba-Rodríguez, J; Dickler, MN; Furlanetto, J; Garcia-Saenz, JA; Guerrero-Zotano, A; Hahn, O; Hudis, C; Hyslop, T; Loibl, S; Martín, M; Martinez-Jañez, N; Mehta, K; Morales, S; Partridge, A; Rodriguez-Martin, C; Winer, E1
E Nagai, S; Futsuhara, K; Hata, S; Inoue, K; Kaneko, S; Kimizuka, K; Kurosumi, M; Nakano, S; Saito, T; Sakurai, T; Yamada, H1
Breitbach, GP; Camara, O; Emons, G; Finas, D; Günthert, A; Kölbl, H; Reimer, T; Rensing, K; Strauss, HG; Thiel, FC1
Argenta, PA; Faratian, D; Geller, MA; Harrison, D; Kay, C; Langdon, SP; Sueblinvong, T; Um, I1
Bachelot, T; Duffy, S; Fleetwood, K; Glanville, J; Jerusalem, G; McCool, R; Varley, D; Zhang, J1
Black, EP; Elledge, R; Kadamyan-Melkumian, V; Massarweh, S; Romond, E; Shelton, B; Stevens, M; Van Meter, E1
Anzeneder, T; Benes, V; Burwinkel, B; Büttner, R; Deuschle, U; Heck, S; Lichter, P; Nicholson, RI; Sauter, G; Schlotter, M; Schneeweiss, A; Schroeter, P; Simon, R; Sinn, HP; Thewes, V; Zapatka, M1
Bak, M; Duun-Henriksen, AK; Kirkegaard, T; Laenkholm, AV; Larsen, SL; Lykkesfeldt, AE; Rasmussen, BB; Yde, CW1
Akiyama, F; Araki, K; Horii, R; Ishida, N; Ito, Y; Ohno, S; Takahashi, S1
Amir, E; Gordon, V; Graham, J; Grenier, D; Niraula, S; Pitz, M1
Bartlett, CH; Bondarenko, I; Colleoni, M; Cristofanilli, M; DeMichele, A; Harbeck, N; Im, SA; Iwata, H; Jiang, Y; Koehler, M; Loi, S; Masuda, N; Ro, J; Slamon, D; Theall, KP; Turner, NC; Verma, S; Zhang, K1
de Boer, R; Derynck, M; Dickler, M; Ellis, M; Forero-Torres, A; Ganju, V; Gendreau, S; He, J; Johnston, S; Krop, IE; Lackner, M; Lee, SC; Levy, G; Mayer, IA; Melichar, B; Morales, S; Perez, EA; Petrakova, K; Piccart, M; Qiu, J; Schmid, P; Vallentin, S; Winer, E; Yardley, DA1
Beyer, JM; Dittmer, A; Dittmer, J; Hellwig, V; Ignatov, A; Kalinski, T; Kirkegaard, T; Lange, T; Leyh, B; Lykkesfeldt, AE; Nass, N; Weiβenborn, C1
Arachchige-Don, AP; Donaldson, MS; Horne, MC; Patriarchi, T; Zimmermann, M1
Argenta, PA; Carson, LF; Downs, LS; Geller, MA; Ghebre, R; Jonson, AL; Judson, PL; Thomas, SG1
Borges, VF; Kabos, P1
Bonebrake, A; Covens, AL; Filiaci, V; Gersell, D; Lee, YC; Lutman, CV1
Crowder, RJ; Ellis, MJ; Gao, F; Guintoli, T; Lin, L; Ma, CX; Phommaly, C; Sanchez, CG1
Chen, L; Kamano, S; Sato, T; Yano, S1
Harwood, KV1
Jakesz, R1
Amant, F; Bines, J; Brufsky, A; Buzdar, A; Chia, S; Federico, M; Fein, L; Gradishar, W; Lowe, E; Mauriac, L; Piccart, M; Possinger, K; Rennie, P; Robertson, JF; Romieu, G; Sapunar, F1
Bliss, JM; Coombes, G; Dodwell, D; Johnston, S; Kilburn, LS1
Nomura, Y1

Reviews

6 review(s) available for fulvestrant and Local Neoplasm Recurrence

ArticleYear
Comparative efficacy of everolimus plus exemestane versus fulvestrant for hormone-receptor-positive advanced breast cancer following progression/recurrence after endocrine therapy: a network meta-analysis.
    Breast cancer research and treatment, 2014, Volume: 143, Issue:1

    Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Estradiol; Everolimus; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Treatment Outcome

2014
Clinical predictors of benefit from fulvestrant in advanced breast cancer: A Meta-analysis of randomized controlled trials.
    Cancer treatment reviews, 2016, Volume: 45

    Topics: Aged; Antineoplastic Agents, Hormonal; Breast Neoplasms; Comparative Effectiveness Research; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Randomized Controlled Trials as Topic

2016
Fulvestrant: a unique antiendocrine agent for estrogen-sensitive breast cancer.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:5

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Delivery Systems; Estradiol; Estrogen Antagonists; Fulvestrant; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local

2010
[Pharmacological and clinical profiles of Fulvestrant (Faslodex(®)) in the treatment of advanced or recurrenced breast cancer].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2012, Volume: 139, Issue:2

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase III as Topic; Down-Regulation; Estradiol; Female; Fulvestrant; Humans; Mice; Molecular Targeted Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Rats; Receptors, Estrogen

2012
Advances in endocrine therapy for breast cancer: considering efficacy, safety, and quality of life.
    Clinical journal of oncology nursing, 2004, Volume: 8, Issue:6

    Topics: Algorithms; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Decision Trees; Drug Administration Schedule; Drug Monitoring; Estradiol; Female; Fulvestrant; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Nurse's Role; Oncology Nursing; Patient Education as Topic; Patient Selection; Postmenopause; Quality of Life; Safety; Selective Estrogen Receptor Modulators; Social Support; Tamoxifen; Treatment Outcome; Triazoles

2004
[Pure antiestrogen for treatment of advanced breast cancers].
    Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58 Suppl

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Tamoxifen; Treatment Outcome

2000

Trials

14 trial(s) available for fulvestrant and Local Neoplasm Recurrence

ArticleYear
Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2-negative breast cancer (FAKTION): overall survival, updated progression-free survival, and expanded biomar
    The Lancet. Oncology, 2022, Volume: 23, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases; Progression-Free Survival; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, ErbB-2; Receptors, Estrogen

2022
Capivasertib in Hormone Receptor-Positive Advanced Breast Cancer.
    The New England journal of medicine, 2023, Jun-01, Volume: 388, Issue:22

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Female; Fulvestrant; Humans; Male; Neoplasm Recurrence, Local; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2

2023
A Single-centre, Retrospective, Observational Analysis of Fulvestrant for Recurrent/metastatic Breast Cancer According to Metastatic Site.
    Anticancer research, 2019, Volume: 39, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Progression-Free Survival; Receptor, ErbB-2; Receptors, Cell Surface; Retrospective Studies

2019
Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial.
    The Lancet. Oncology, 2020, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Double-Blind Method; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Fulvestrant; Humans; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Pyrimidines; Pyrroles; Receptors, Estrogen; Salvage Therapy; Survival Rate

2020
Phase III randomized study of taselisib or placebo with fulvestrant in estrogen receptor-positive, PIK3CA-mutant, HER2-negative, advanced breast cancer: the SANDPIPER trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2021, Volume: 32, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Imidazoles; Neoplasm Recurrence, Local; Oxazepines; Phosphatidylinositol 3-Kinases; Quality of Life; Receptor, ErbB-2; Receptors, Estrogen

2021
Evaluating the addition of bevacizumab to endocrine therapy as first-line treatment for hormone receptor-positive metastatic breast cancer: a pooled analysis from the LEA (GEICAM/2006-11_GBG51) and CALGB 40503 (Alliance) trials.
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 117

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Breast Neoplasms; Evaluation Studies as Topic; Female; Follow-Up Studies; Fulvestrant; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Soft Tissue Neoplasms; Survival Rate; Tamoxifen

2019
Phase II study of fulvestrant 250 mg/month in patients with recurrent or metastatic endometrial cancer: a study of the Arbeitsgemeinschaft Gynäkologische Onkologie.
    Gynecologic oncology, 2013, Volume: 129, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Drug Administration Schedule; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Injections, Intramuscular; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Receptors, Estrogen; Receptors, Progesterone

2013
Predicting response to the anti-estrogen fulvestrant in recurrent ovarian cancer.
    Gynecologic oncology, 2013, Volume: 131, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fluorescent Antibody Technique; Fulvestrant; Humans; Immunohistochemistry; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Tissue Array Analysis

2013
A phase II study of combined fulvestrant and everolimus in patients with metastatic estrogen receptor (ER)-positive breast cancer after aromatase inhibitor (AI) failure.
    Breast cancer research and treatment, 2014, Volume: 143, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Everolimus; Female; Fulvestrant; Humans; Immunosuppressive Agents; Middle Aged; Neoplasm Recurrence, Local; Receptors, Estrogen; Sirolimus; TOR Serine-Threonine Kinases; Treatment Failure

2014
Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phas
    The Lancet. Oncology, 2016, Volume: 17, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Disease-Free Survival; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Mutation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases; Piperazines; Pyridines; Receptor, ErbB-2; Treatment Outcome

2016
Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 trial.
    The Lancet. Oncology, 2016, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Antagonists; Female; Follow-Up Studies; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Salvage Therapy; Survival Rate

2016
A phase II study of fulvestrant in the treatment of multiply-recurrent epithelial ovarian cancer.
    Gynecologic oncology, 2009, Volume: 113, Issue:2

    Topics: Alkaline Phosphatase; Antineoplastic Agents, Hormonal; Bone and Bones; Collagen Type I; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Peptides

2009
Phase II study of fulvestrant in recurrent/metastatic endometrial carcinoma: a Gynecologic Oncology Group study.
    Gynecologic oncology, 2011, Volume: 120, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Disease-Free Survival; Endometrial Neoplasms; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Receptors, Estrogen; Receptors, Progesterone

2011
Double-blind, randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Apr-01, Volume: 26, Issue:10

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Kaplan-Meier Estimate; Neoplasm Recurrence, Local; Placebos; Postmenopause; Quality of Life; Receptors, Estrogen

2008

Other Studies

33 other study(ies) available for fulvestrant and Local Neoplasm Recurrence

ArticleYear
[Successful Treatment of Estrogen Receptor Positive, HER2 Negative Breast Cancer with Life-Threatening Multiple Bone Metastases Using the Combination of Fulvestrant and Palbociclib-A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2021, Volume: 48, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Piperazines; Pyridines; Quality of Life; Receptor, ErbB-2; Receptors, Estrogen

2021
NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer.
    Scientific reports, 2022, 02-04, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Endocrine Gland Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Mice; Neoplasm Recurrence, Local; Receptor, ErbB-2; Receptors, G-Protein-Coupled; Receptors, Neuropeptide Y; Tamoxifen

2022
Factors associated with overall survival after recurrence in patients with ER-positive/HER2-negative postmenopausal breast cancer: an ad hoc analysis of the JBCRG-C06 Safari study.
    Japanese journal of clinical oncology, 2022, May-31, Volume: 52, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies

2022
[A Case of Postoperative Pulmonary Metastasis of Breast Cancer with Complete Response by Abemaciclib plus Fulvestrant Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2022, Volume: 49, Issue:5

    Topics: Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Female; Fulvestrant; Humans; Lung Neoplasms; Mastectomy; Neoplasm Recurrence, Local

2022
Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast Cancer.
    Molecular cancer therapeutics, 2022, 06-01, Volume: 21, Issue:6

    Topics: Breast Neoplasms; Clinical Trials as Topic; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Indazoles; Neoplasm Recurrence, Local; Pyridines

2022
Clinical Translation: Targeting the Estrogen Receptor.
    Advances in experimental medicine and biology, 2022, Volume: 1390

    Topics: Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Receptors, Estrogen; Tamoxifen

2022
PAQR8 promotes breast cancer recurrence and confers resistance to multiple therapies.
    Breast cancer research : BCR, 2023, 01-03, Volume: 25, Issue:1

    Topics: Animals; Drug Resistance, Neoplasm; Estrogens; Fulvestrant; Lapatinib; Mice; Neoplasm Recurrence, Local; Receptor, ErbB-2; Receptors, Progesterone

2023
ERβ1 Sensitizes and ERβ2 Desensitizes ERα-Positive Breast Cancer Cells to the Inhibitory Effects of Tamoxifen, Fulvestrant and Their Combination with All-Trans Retinoic Acid.
    International journal of molecular sciences, 2023, Feb-13, Volume: 24, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Resistance, Neoplasm; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Protein Isoforms; Tamoxifen; Tretinoin

2023
Real-world effectiveness of fulvestrant monotherapy as first endocrine treatment in patients with metastatic breast cancer.
    The breast journal, 2020, Volume: 26, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Breast Neoplasms; Databases, Factual; Disease-Free Survival; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Progression-Free Survival; Receptor, ErbB-2; Retrospective Studies

2020
Inhibiting Pathways Predicted From a Steroid Hormone Gene Signature Yields Synergistic Antitumor Effects in NSCLC.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2020, Volume: 15, Issue:1

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Fulvestrant; Lung Neoplasms; Mice; Neoplasm Recurrence, Local; Signal Transduction; Xenograft Model Antitumor Assays

2020
Factors associated with prolonged overall survival in patients with postmenopausal estrogen receptor-positive advanced breast cancer using real-world data: a follow-up analysis of the JBCRG-C06 Safari study.
    Breast cancer (Tokyo, Japan), 2020, Volume: 27, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Female; Follow-Up Studies; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate

2020
Capivasertib inhibits a key pathway in metastatic breast cancer.
    The Lancet. Oncology, 2020, Volume: 21, Issue:3

    Topics: Aromatase; Breast Neoplasms; Estrogens; Fulvestrant; Humans; Neoplasm Recurrence, Local

2020
[Challenges and countermeasures in the treatment of luminal breast cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2020, Mar-23, Volume: 42, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Resistance, Neoplasm; Estrogen Receptor Modulators; Fulvestrant; Humans; Neoplasm Recurrence, Local; Receptors, Estrogen; Vascular Endothelial Growth Factor A

2020
Fulvestrant plus capivasertib for metastatic breast cancer.
    The Lancet. Oncology, 2020, Volume: 21, Issue:5

    Topics: Aromatase; Aromatase Inhibitors; Estrogens; Fulvestrant; Humans; Neoplasm Recurrence, Local

2020
Fulvestrant plus capivasertib for metastatic breast cancer.
    The Lancet. Oncology, 2020, Volume: 21, Issue:5

    Topics: Aromatase; Aromatase Inhibitors; Estrogens; Fulvestrant; Humans; Neoplasm Recurrence, Local

2020
Fulvestrant plus capivasertib for metastatic breast cancer - Authors' reply.
    The Lancet. Oncology, 2020, Volume: 21, Issue:5

    Topics: Aromatase; Aromatase Inhibitors; Estrogens; Fulvestrant; Humans; Neoplasm Recurrence, Local

2020
Concomitant fulvestrant with reirradiation for unresectable locoregional recurrent estrogen receptor positive (ER+) breast cancer: A case report and narrative review.
    Medicine, 2020, Jul-24, Volume: 99, Issue:30

    Topics: Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Lymphatic Metastasis; Mastectomy, Modified Radical; Middle Aged; Narrative Medicine; Neoplasm Recurrence, Local; Re-Irradiation; Receptors, Estrogen

2020
Estrogen receptor α/prolactin receptor bilateral crosstalk promotes bromocriptine resistance in prolactinomas.
    International journal of medical sciences, 2020, Volume: 17, Issue:18

    Topics: Adolescent; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Bromocriptine; Cell Line, Tumor; Cyclin D1; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Hypophysectomy; Male; MAP Kinase Signaling System; Middle Aged; Neoplasm Recurrence, Local; Pituitary Gland; Pituitary Neoplasms; Prolactin; Prolactinoma; Rats; Receptors, Prolactin; Young Adult

2020
Cancer stem cells: Culprits in endocrine resistance and racial disparities in breast cancer outcomes.
    Cancer letters, 2021, 03-01, Volume: 500

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Receptors, Estrogen; Signal Transduction

2021
Icb-1 expression inhibits growth and fulvestrant response of breast cancer cells and affects survival of breast cancer patients.
    Archives of gynecology and obstetrics, 2021, Volume: 304, Issue:1

    Topics: Adult; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Computational Biology; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Neoplasm Recurrence, Local; Reverse Transcriptase Polymerase Chain Reaction

2021
[Locally Advanced Breast Cancer Successfully Treated with Abemaciclib and Fulvestrant-A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:13

    Topics: Aged; Aminopyridines; Axilla; Benzimidazoles; Breast Neoplasms; Female; Fulvestrant; Humans; Lymph Node Excision; Lymph Nodes; Mastectomy; Neoplasm Recurrence, Local

2020
[A Case of Hormone Receptor‒Positive HER2‒Negative Advanced/Recurrent Breast Cancer with 1.5 Years Withdrawal Period of Palbociclib Showed a Good Response Treated by Abemaciclib and Fulvestrant].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2021, Volume: 48, Issue:5

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Piperazines; Protein Kinase Inhibitors; Pyridines

2021
Outcomes of fulvestrant therapy among japanese women with advanced breast cancer: a retrospective multicenter cohort study (JBCRG-C06; Safari).
    Breast cancer research and treatment, 2017, Volume: 163, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Japan; Kaplan-Meier Estimate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Retrospective Studies; Treatment Failure; Treatment Outcome

2017
Impact of Visceral Metastasis on Efficacy of Fulvestrant in Patients with Hormone Receptor-positive Recurrent Breast Cancer.
    Anticancer research, 2018, Volume: 38, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Receptors, Steroid; Treatment Outcome; Viscera

2018
Multicenter Observational Study of Fulvestrant 500 mg in Postmenopausal Japanese Women with Estrogen Receptor-Positive Advanced or Recurrent Breast Cancer after Prior Endocrine Treatment (SBCCSG29 Study).
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2019, Volume: 86, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Asian People; Breast Neoplasms; Cohort Studies; Combined Modality Therapy; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Prospective Studies; Receptors, Estrogen; Retrospective Studies; Time Factors; Treatment Outcome

2019
Reprogramming of the ERRα and ERα target gene landscape triggers tamoxifen resistance in breast cancer.
    Cancer research, 2015, Feb-15, Volume: 75, Issue:4

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ERRalpha Estrogen-Related Receptor; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoplasm Recurrence, Local; Nuclear Receptor Coactivator 3; Receptors, Estrogen; Tamoxifen

2015
Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer.
    BMC cancer, 2015, Apr-08, Volume: 15

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; Aurora Kinase B; Biomarkers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Mitosis; Neoplasm Recurrence, Local; Organophosphates; Phosphorylation; Prognosis; Protein Kinase Inhibitors; Proteolysis; Quinazolines; Survival Analysis; Tamoxifen

2015
Efficacy of fulvestrant 500 mg in Japanese postmenopausal advanced/recurrent breast cancer patients and factors associated with prolonged time-to-treatment failure.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Retrospective Studies; Time-to-Treatment

2015
Expression of transmembrane protein 26 (TMEM26) in breast cancer and its association with drug response.
    Oncotarget, 2016, Jun-21, Volume: 7, Issue:25

    Topics: Biomarkers, Pharmacological; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Integrin beta1; MCF-7 Cells; Membrane Proteins; Neoplasm Recurrence, Local; RNA

2016
Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival.
    Cell cycle (Georgetown, Tex.), 2016, Volume: 15, Issue:23

    Topics: Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Nucleus; Cyclin G2; Cyclin-Dependent Kinases; Disease-Free Survival; Estradiol; Estrogens; Extracellular Signal-Regulated MAP Kinases; Female; Fulvestrant; Gene Knockdown Techniques; Humans; Metformin; Mitogen-Activated Protein Kinase Kinases; Neoplasm Recurrence, Local; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-raf; Receptors, Estrogen; Retinoblastoma Protein; RNA Interference; Signal Transduction; Survival Analysis; Up-Regulation

2016
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer.
    Breast cancer research : BCR, 2011, Mar-01, Volume: 13, Issue:2

    Topics: Aminopyridines; Antineoplastic Agents, Hormonal; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Estradiol; Estrogens; Everolimus; Female; Fulvestrant; Humans; Imidazoles; Morpholines; Mutation; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Quinolines; Receptors, Estrogen; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2011
[New strategies against breast carcinoma. To outwit the resistance tendency of tumor cells].
    MMW Fortschritte der Medizin, 2005, Mar-10, Volume: 147, Issue:10

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Resistance, Neoplasm; Estradiol; Female; Fulvestrant; Humans; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Time Factors; Triazoles

2005
Combining fulvestrant (Faslodex) with continued oestrogen suppression in endocrine-sensitive advanced breast cancer: the SoFEA trial.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2008, Volume: 20, Issue:5

    Topics: Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Receptors, Estrogen

2008