fucosyl-gm1-ganglioside and Cholera

fucosyl-gm1-ganglioside has been researched along with Cholera* in 1 studies

Other Studies

1 other study(ies) available for fucosyl-gm1-ganglioside and Cholera

ArticleYear
Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site.
    Scientific reports, 2019, 08-22, Volume: 9, Issue:1

    Cholera is a life-threatening diarrhoeal disease caused by the human pathogen Vibrio cholerae. Infection occurs after ingestion of the bacteria, which colonize the human small intestine and secrete their major virulence factor - the cholera toxin (CT). The GM1 ganglioside is considered the primary receptor of the CT, but recent studies suggest that also fucosylated receptors such as histo-blood group antigens are important for cellular uptake and toxicity. Recently, a special focus has been on the histo-blood group antigen Lewis

    Topics: Binding Sites; Blood Group Antigens; Cholera; Cholera Toxin; G(M1) Ganglioside; Glycosylation; Humans; Protein Binding; Vibrio cholerae

2019