fucosyl-gm1-ganglioside has been researched along with Cholera* in 1 studies
1 other study(ies) available for fucosyl-gm1-ganglioside and Cholera
Article | Year |
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Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site.
Cholera is a life-threatening diarrhoeal disease caused by the human pathogen Vibrio cholerae. Infection occurs after ingestion of the bacteria, which colonize the human small intestine and secrete their major virulence factor - the cholera toxin (CT). The GM1 ganglioside is considered the primary receptor of the CT, but recent studies suggest that also fucosylated receptors such as histo-blood group antigens are important for cellular uptake and toxicity. Recently, a special focus has been on the histo-blood group antigen Lewis Topics: Binding Sites; Blood Group Antigens; Cholera; Cholera Toxin; G(M1) Ganglioside; Glycosylation; Humans; Protein Binding; Vibrio cholerae | 2019 |