fructooligosaccharide and Colitis--Ulcerative

fructooligosaccharide has been researched along with Colitis--Ulcerative* in 5 studies

Other Studies

5 other study(ies) available for fructooligosaccharide and Colitis--Ulcerative

ArticleYear
Letter: 1-kestose, the smallest fructooligosaccharide component, protection for mild to moderate ulcerative colitis patients-authors' reply.
    Alimentary pharmacology & therapeutics, 2023, Volume: 57, Issue:11

    Topics: Colitis, Ulcerative; Humans; Oligosaccharides; Trisaccharides

2023
Letter: 1-kestose, the smallest fructooligosaccharide component, protection for mild to moderate ulcerative colitis patients.
    Alimentary pharmacology & therapeutics, 2023, Volume: 57, Issue:11

    Topics: Colitis, Ulcerative; Humans; Oligosaccharides; Trisaccharides

2023
Fermentation patterns of prebiotics fructooligosaccharides-SCFA esters inoculated with fecal microbiota from ulcerative colitis patients.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 180

    Ulcerative colitis (UC) is believed to arise from an imbalance between the intestinal microbiota and mucosal immunity, leading to excessive intestinal inflammation. Modulating the gut microbial community through dietary components presents a valuable strategy in aiding the treatment of UC. In this study, esters formed by binding of well-known prebiotics, fructooligosaccharides (FOS), with short chain fatty acids (SCFAs) via both enzymatic and chemical methods were evaluated for their impact on the gut microbiota of UC patients. An in vitro human colonic fermentation model was employed to monitor changes in total carbohydrates and SCFAs production during the fermentation of these esters by microbiota from patients with active and remission UC. The results showed that pronounced abundance of [Ruminococcus]_gnavus_group, Escherichia_Shigella, Lachnoclostridium, Klebsiella and other potential pathogens were detected in the fecal samples from UC patients, with a milder condition observed during the remission phase. Significant higher levels of corresponding SCFA were observed in the groups with addition of FOS-SCFAs esters during fermentation. Butyrylated fructooligosaccharides (B-FOS) and propionylated fructooligosaccharides (P-FOS) by enzymatic synthesis successfully promoted the proliferation of Bifidobacterium and inhibited Clostridium_sensu_stricto_1 and Klebsiella. Overall, B-FOS and P-FOS exhibit promising potential for restoring intestinal homeostasis and alleviating intestinal inflammation in individuals with UC.

    Topics: Colitis, Ulcerative; Fatty Acids, Volatile; Feces; Fermentation; Humans; Inflammation; Microbiota; Prebiotics

2023
Butyl-fructooligosaccharides modulate gut microbiota in healthy mice and ameliorate ulcerative colitis in a DSS-induced model.
    Food & function, 2022, Feb-21, Volume: 13, Issue:4

    Topics: Animals; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Mice; Oligosaccharides

2022
RETRACTED: Dietary oligosaccharides attenuate DSS-induced colitis in mice, induce PGlyRP3 expression, and inhibit NF-κB and MEK/ERK signaling.
    Cellular immunology, 2020, Volume: 354

    This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).\ \ This article has been retracted at the request of the Editors.\ \ The Editors of Cellular Immunology have been informed by Elsevier that the article had been submitted to another journal while under consideration at "Cellular Immunology", which is a case of double submission.\ \ Based on the above infringement and its deleterious impact on the mutual trust necessary for the evaluation of scientific work - the corresponding authors had stated that the article was not submitted to another journal - it was decided to retract this article.

    Topics: Animals; Anti-Inflammatory Agents; Caco-2 Cells; Carrier Proteins; Colitis; Colitis, Ulcerative; Dextran Sulfate; Diet; Disease Models, Animal; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Oligosaccharides; PPAR gamma; Up-Regulation

2020